Newcastle University Medicine Malaysia

Staff Profile

Dr Moe Kyaw Thu

Associate Professor (Non-Clinical)

Background

Current Position

 

Aug 2014  -- Associate Professor (Non-clinical), Newcastle University Medicine Malaysia

  

Honorary appointments

 

Mar 2013 -- Honorary Academic Fellow, Baker IDI Heart and Diabetes Institute, Melbourne, Australia

Mar 2014 -- Visiting Scientist, National Neuroscience Institute, SingHealth, Singapore

  

Academic Qualifications

 

PGCert (2015) -- Newcastle University, UK (Medical Education)

FAHA (2011)  -- American Heart Association (Basic Sciences in Cardiology)

M.Sc (2005)   -- The University of Manchester, UK (Bioinformatics)

Ph.D (1999)   -- National University of Singapore (NUS), Singapore (Microbiology)

MBBS (1986) -- Institute of Medicine (1), Rangoon, Burma (Medicine/ Surgery)

 

Background

I am a trained medical doctor and researcher with nearly 30 years experience. I spent my last twenty-five years doing research in cellular and molecular biology.

I secured and managed more than 4.2 million Singapore dollars grants from Singapore Biomedical Research Council (BMRC), Singapore National Research Council (NMRC), SingHealth Research, Duke-NUS-Goh Foundation, Economic Development Board (Singapore), and Bayer Schering Pharma (Germany) as a principal investigator, co-principal investigator, or collaborator during my term as a principal research scientist at National Heart Centre Singapore (NHCS) during October 2003 to July 2014.

These research grants include reverse epigenetics of hyperhomocysteinemia in cerebrovascular diseases, searching for novel biomarkers of ischaemic heart failure, molecular mechanism of statin-induced diabetes in rodent models, obesity-induced vascular remodeling in vivo and in vitro systems, molecular switch-on switch-off mechanism of vascular Nox4 by tumor necrosis factor-alpha, and investigation of cardioprotective mechanism of a novel compound.


Awards and Honors

Science

  • Best Poster Award – Basic Sciences (Finalist) (Senior Author) – 21st  SGH Annual Scientific Meeting, 10-11 April 2015, Singapore General Hospital, Singapore
  • Best Oral Presenter (Senior Author) - 20th ASEAN Federation Of Cardiology Congress 2014, 12-15 June 2014, Kuala Lumpur City Centre (KLCC), Malaysia
  • Best Poster Award – Basic Sciences (Finalist) (Senior Author) – 20th SGH Annual Scientific Meeting, 4-6 April 2013, Singapore General Hospital, Singapore
  • Honorary Academic Fellow, Baker IDI Heart and Diabetes Institute, Melbourne, Australia (March 2013)
  • Fellow of American Heart Association (FAHA) – Basic Sciences in Cardiology – American Heart Association (Oct 2011)
  • Adjunct Investigator (Singapore Eye Research Institute, SingHealth, Singapore) (March 2010)
  • Honorary Academic Fellow, Baker IDI Heart and Diabetes Institute, Melbourne, Australia (March 2009)
  • SingHealth Sabbatical Fellowship Award (February 2009)
  • Best oral presentation-Basic Sciences (finalist) (Senior Author) –Singapore General Hospital 19th Annual Scientific Meeting 2011, 19-20 April 2011, Singapore General Hospital, Singapore

  • Best Poster Award – Clinical Research (Finalist) (Senior Author) – SingHealth Duke-NUS Scientific Congress 2010, 15-16 October 2010, Suntec International Convention & Exhibition Centre, Singapore
  • Best Oral Presentation (Senior Author) – 22nd Annual Scientific Meeting, Singapore Cardiac Society, 27-28 March 2010, Grand Copthorne Waterfront Hotel, Singapore
  • Young Investigator Award (YIA)-Second runner-up (Senior Author) 21st  Annual Scientific Meeting, Singapore Cardiac Society, 21-22 March 2009, Grand Copthorne Waterfront Hotel, Singapore
  • Young Investigator Award (YIA)-First runner-up (Senior Author) 20th Annual Scientific Meeting, Singapore Cardiac Society, 22-23 March 2008, Grand Copthorne Waterfront Hotel, Singapore
  • Young Investigator Award (YIA)-Second runner-up (Senior Author) 20th Annual Scientific Meeting, Singapore Cardiac Society, 22-23 March 2008, Grand Copthorne Waterfront Hotel, Singapore
  • Best Poster Award (Scientist) 16th Singapore General Hospital Scientific Meeting, 27-28 April 2007, Singapore.
  • Best Oral Paper (Scientist) Finalist. 15th Annual Scientific Meeting, 21-22 April 2006, Singapore General Hospital, Singapore
  • Best Oral Paper Finalist (Senior Author). ICBPE 2006 (International conference on biomedical, pharmaceutical engineering, 11-14 December, Orchard Hotel, Singapore
  • Young Scientist - 32nd Annual Scientific Seminar, Malaysian Society of Parasitology and Tropical Medicine. 29-30th March 1996, Perdanasiswa, University Malaya, Kuala Lumpur, Malaysia

Social

  • President (Elected, 1995-1996), Postgraduate Society, National University of Singapore (NUS),  Singapore



Teaching

Biomedical Sciences Course @ NUMed

Module Leader:       BMN2003 (Molecular Medicine)

                                BMN2004 (Cell and Molecular Biology of the Immune System)

                                BMN1005 (Microbiology and Immunology)

 

Lecturer:                  BMN2003 (Molecular Medicine)

                                BMN2004 (Cell and Molecular Biology of the Immune System)

                                BMN2002 (Cell and Molecular Biosciences)

                                BMN2011 (The Nervous System and Respiratory Diseases)

                                BMN2012 (Clinical Immunology and Viral Pathogens)

                                BMN1005 (Microbiology and Immunology)

                                BMN1006 (Pharmacology)

 

MBBS Programme @ NUMed

            Lecturer:                      Stage 1 (Cardiovascular,  Renal & Respiratory Medicine 1 & 2)

                                                Stage 1 (Life Cycle 1 &2)

                                                Stage 1 (Molecules to Disease)

                                                Stage 1 (Induction and Student Support)

                                                Stage 1 (Clinical Skills and Communication)

                                                Stage 1 (Nutrition, Metabolism & Endocrinology 1&2)

                                                Stage 2 (Clinical Sciences & Investigative Medicine 1)

                                                Stage 4 (Clinical Sciences & Investigative Medicine 2)

 

Publications

  • Moe KT, Yin NO, NayLynn TM, Khairunnisa K, Wong MC, Chin-Dusting J, Wong P. Tumor Necrosis Factor (TNF)-alpha-induced Nuclear Factor (NF)-kB activation in human cardiomyocytes is mediated by NADPH Oxidase. Journal of Physiology and Biochemistry 2014, 70(3), 769-779.
  • Moe KT, Naylynn TM, Yin NO, Khairunnisa K, Allen JC, Wong MC, Chin-Dusting J, Wong P. Tumor necrosis factor-α induces aortic intima-media thickening via perivascular adipose tissue inflammation. Journal of Vascular Research 2013, 50(3), 228-237.
  • Liew R, Khairunnisa K, Gu Y, Tee N, Yin NO, Naylynn TM, Moe KT. Role of tumor necrosis factor-α in the pathogenesis of atrial fibrosis and development of an arrhythmogenic substrate. Circ J;77(5):1171-9. 2013.
  • Khong S, Andrews K, Huynh N, Venardos K, Aprico A, Michell D, Zarei M, Moe KT, Dusting G, Kaye D, Chin-Dusting J. Arginase II inhibition prevents nitrate tolerance.Br J Pharmacol.166(7):2015-23. 2012.
  • Robinson R, Ho CE, Tan QS, Luu CD, Moe KT, Cheung CY, Wong TY, Barathi VA. Fluvastatin down regulates VEGF-A expression in TNF-{alpha} induced retinal vessel tortuosity. Invest Ophthalmol Vis Sci. 27;52(10):7423-31. 2011.
  • Moe KT, Yin NO, Naylynn TM, Khairunnisa K, Wutyi MA, Gu Y, Atan MS, Wong MC, Koh TH, Wong P. Nox2 and Nox4 mediate tumor necrosis factor-alpha-induced ventricular remodeling in mice. J Cell Mol Med. 2011 15(12): 2601-13. 2011.
  • Moe KT, Wong P. Current trends in diagnostic biomarkers of acute coronary syndrome.Ann Acad Med Singapore. 2010 Mar;39(3):210-5. 2010.
  • Ng SY, Reboud J, Wang KY, Tang KC, Zhang L, Wong P, Moe KT, Shim W, Chen Y. Label-free impedance detection of low levels of circulating endothelial progenitor cells for point-of-care diagnosis. Biosens Bioelectron. 2010 Jan 15;25(5):1095-101. 2010.
  • Moe KT, Woon FP, DeSilva DA, Wong P, Koh TH, Kingwell B, Chin-Dusting J, Wong MC. Association of acute ischemic stroke with the MTHFR polymorphism but not with NOS3 gene polymorphisms in a Singapore population. Eur J Neurol. 15: 1309-1314. 2008.
  • DeSilva DA, Woon FP, Moe KT, Chen CL, Chang HM, Wong MC. Concomitant coronary artery disease among asian ischaemic stroke patients. Ann Acad Med Singapore. Jul;37(7):573-5. 2008.
  • Moe KT, Lim ST, Wong P, Chua T, DeSilva DA, Koh TH, Wong MC, Chin-Dusting J. Association analysis of endothelial nitric oxide synthase gene polymorphism with primary hypertension in a Singapore population. J Hum Hypertens 2006 Dec;20(12):956-63. 2006.
  • Moe KT, Aulia S, Jiang F, Chua YL, Koh TH, Wong MC, Dusting GJ. Differential upregulation of Nox homologues of NADPH oxidase by tumor necrosis factor-alpha in human aortic smooth muscle and embryonic kidney cells. J Cell Mol Med. 2006 Jan-Mar;10(1):231-9. 2006.
  • Tan EK, Yew K, Chua E, Puvan K, Shen H, Lee E, Puong KY, Zhao Y, Pavanni R, Wong MC, Jamora D, DeSilva D, Moe KT, Woon FP, Yuen Y, Tan L. PINK1 mutations in sporadic early-onset Parkinson's disease. Mov Disord. 2006 Jun;21(6):789-93. 2006.
  • Goh ALH, Moe KT, Chen XQ, Tan KSW. Identification and characterization of an MRE11 homologue in Plasmodium falciparum. Experimental Parasitology Volume 105 (1): 42. 2003.
  • Moe KT, Zhiliang J, Barathi A, Beuerman RW. Expression of collagen genes in the postnatal rabbit sclera. Hong Kong Journal of Ophthalmology;6(1): 7-12. 2002.
  • Barathi A, Moe KT, Beuerman RW. Dimensional growth of the rabbit eye. Cells Tissues Organs;171(4): 276-85. 2002.
  • Moe KT, Zhiliang J, Barathi A, Beuerman RW. Differential expression of glyceraldehyde-3-phosphate dehydrogenase (GAPDH), b actin and hypoxanthine phosphoribosyltransferase (HPRT) in postnatal rabbit sclera. Curr Eye Res;23(1): 44-50. 2001.
  • Moe KT, Singh M, Howe J, Ho LC, Tan SW, Chen XQ, Yap EH. Development of Blastocystis hominis cysts into vacuolar forms in vitro. Parasitol Res. 85(2):103-8. 1999.
  • Moe KT, Singh M, Gopalakrishnakone P, Ho LC, Tan SW, Chen XQ, Yap EH. Cytopathic effect of Blastocystis hominis after intramuscular inoculation into laboratory mice. Parasitol Res. 84(6):450-4. 1998.
  • Tan SW, Singh M, Ho LC, Howe J, Moe KT, Chen XQ, Ng GC, Yap EH. Survival of Blastocystis hominis clones after exposure to a cytotoxic monoclonal antibody. Int J Parasitol. 27(8):947-54. 1997.
  • Chen XQ, Singh M, Ho LC, Moe KT, Tan SW, Yap EH. A survey of Blastocystis sp. in rodents. Lab Anim Sci. 47(1):91-4. Review. 1997.
  • Moe KT, Singh M, Howe J, Ho LC, Tan SW, Chen XQ, Ng GC, Yap EH. Experimental Blastocystis hominis infection in laboratory mice. Parasitol Res. 83(4):319-25. 1997.
  • Chen XQ, Singh M, Ho LC, Tan SW, Ng GC, Moe KT, Yap EH. Description of a blastocystis species from Rattus norvegicus. Parasitol Res. 83(4):313-8. 1997.
  • Tan SW, Ho LC, Moe KT, Chen XQ, Ng GC, Yap EH, Singh M. Production and characterization of murine monoclonal antibodies to Blastocystis hominis. Int J Parasitol. 26(4):375-81. 1996.
  • Tan SW, Singh M, Thong KT, Ho LC, Moe KT, Chen XQ, Ng GC, Yap EH. Clonal growth of Blastocystis hominis in soft agar with sodium thioglycollate. Parasitol Res. 82(8):737-9. 1996.
  • Singh M, Ho LC, Yap AL, Ng GC, Tan SW, Moe KT, Yap EH. Axenic culture of reptilian Blastocystis isolates in monophasic medium and speciation by karyotypic typing. Parasitol Res. 82(2):165-9. 1996.
  • Tan SW, Singh M, Yap EH, Ho LC, Moe KT, Howe J, Ng GC. Colony formation of Blastocystis hominis in soft agar. Parasitol Res. 82(4):375-7. 1996.
  • Moe KT, Singh M, Howe J, Ho LC, Tan SW, Ng GC, Chen XQ, Yap EH. Observations on the ultrastructure and viability of the cystic stage of Blastocystis hominis from human feces. Parasitol Res. 82(5):439-44. 1996.
  • Thu MK, Beuerman RW, Liang JZ. AF308570 (http://www.ncbi.nlm.nih.gov/)Oryctolagus cuniculus putative muscarinic receptor M4 mRNA, partial cdsgi|12240082|gb|AF308570.1|AF308570[12240082]15-JAN-2001. 2011.
  • Thu MK, Beuerman RW, Liang JZ. AF309819 (http://www.ncbi.nlm.nih.gov/)Oryctolagus cuniculus beta-actin mRNA, partial cdsgi|12240085|gb|AF309819.1|AF309819[12240085]15-JAN-2001. 2011.
  • Thu MK, Beuerman RW. AF243516 (http://www.ncbi.nlm.nih.gov/)Oryctolagus cuniculus putative epidermal growth factor receptor mRNA, partial cdsgi|7649162|gb|AF243516.1|AF243516[7649162]26-APR-2000. 2000.
  • Thu MK, Beuerman RW. AF295598 (http://www.ncbi.nlm.nih.gov/)Oryctolagus cuniculus putative collagen XI mRNA, partial cdsgi|9945023|gb|AF295598.1|AF295598[9945023]30-AUG-2000. 2000.
  • Thu MK, Beuerman RW. AF309685 (http://www.ncbi.nlm.nih.gov/)Oryctolagus cuniculus integrin beta 3 mRNA, partial cdsgi|10954086|gb|AF309685.1|AF309685[10954086]24-OCT-2000. 2000.
  • Tripathi M, Zhang CW, Singh BK, Lim SY, Sinha RA, Zhou J, Moe KT, De Silva D, Angeli V, Yen P. Caffeine inhibits aortic smooth muscles cell’s proliferation by modulation in autophagy –Wnt signaling. In: New Advances in Metabolism Research Symposium. 2016, Duke-NUS Medical School, Singapore.
  • Tripathi M, Zhang CW, Singh BK, Sinha RA, Moe KT, Lim KL, De Silva D, Yen P. Vitamin therapy reverses induction of ER stress, autophagic block and PP2A-mTORC1 activation by hyperhomocysteinemia in brain. In: NNI - Research Day Symposium. 2016, Tan Tock Seng hospital campus, Singapore.
  • Tripathi M, Zhang CW, Singh BK, Sinha RA, Moe KT, DeSilva D, Yen P. Hyperhomocysteinemia increases ER stress and Impairs autophagic flux in murine therapy brain that is reversible with vitamin therapy. In: Society for Neuroscience (SFN). 2015, McCormick Convention Centre, Chicago, USA.
  • Tripathi M, Zhang CW, Singh BK, Sinha RA, Moe KT, DeSilva D, Yen P. Vitamin B12, B6 and Folate Supplementation Rescues Hyperhomocysteinemia-Induced Endoplasmic Reticulum Stress and Autophagy Inhibition in Mouse Brain. In: Asia Pacific Stroke Conference. 2015, Kuala Lumpur, Malaysia.
  • Tripathi M, Kwek XY, Sinha RA, Singh BK, Yiu YW, Moe KT, DeSilva DA, Yen P. Vitamin B12 and folate supplementation rescues Hyperhomcysteinemia-induced Endoplasmic Reticulum Stress and autophagy inhibition in mouse brain. 2015, Singapore, Southeast Asia.
  • Khairunnisa K, Kwek XY, Moe KT. A mechanistic study of statin-induced diabetes mellitus in a mouse model. In: SGH 21st Annual Scientific Meeting. 2015, Singapore, Southeast Asia.
  • Kwek XY, Khairunnisa K, Ghosh S, Moe KT, Sim D. Identification of a sensitive and specific biomarker protein profile of acute decompensated heart failure. In: 27th Annual Scientific Meeting, Singapore Cardiac Society. 2015, Singapore, Southeast Asia.
  • Khairunnisa K, Kwek XY, Lim SQ, Moe KT. (2014) Fluvastatin attenuates obesity-induced vascular remodeling via mediation of NADPH oxidase4 (Nox4), 12-15 June 2014, , Kuala Lumpur City Centre (KLCC), Malaysia. In: 20th ASEAN Federation Of Cardiology Congress 2014. 2014, Kuala Lumpur, Malaysia.
  • Lim SQ, Khairunnisa K, Kwek XY, Yin NO, Moe KT. (2013) Protein Phosphatase 2C Regulates AMP-Activated Protein Kinase in Obese Heart. 5-6 April SGH 20th Annual Scientific Meeting, Singapore. 2013.
  • Kwek XY, Khairunnisa K, Lim SQ, Yin NO, Moe KT. (2013) Increased Arterial Stiffness Is Observed In Ascending Aorta of High Fat Diet-Induced Hypertensive Obese Mice. 5-6 April SGH 20th Annual Scientific Meeting, Singapore. 2013.
  • Khairunnisa K, Kwek XY, Lim SQ, Yin NO, Moe KT. (2013) High Fat Diet-Induced Vascular Remodeling in Abdominal Aorta of Obese Mice. 5-6 April SGH 20th Annual Scientific Meeting, Singapore. 2013.
  • Ziemann MD, Kaipananickal H, Kaspi A, DeSilva DA, Moe KT, El-Osta A. (2012) Patterns of genome-wide DNA methylation regulated by homocysteine. Australian Epigenetic Alliance Scientific Conference. 7-9 May, Adelaide, Australia. 2012.
  • Moe KT, Wong MC, Wong P. (2012) Fluvastatin attenuates high fat diet-induced increased intima-media thickness and smooth muscle cell proliferation in the abdominal aorta via mediation of TGF-beta and Nox4. Scientific Sections 2012, American Heart Associations. 4-6 Nov 2012 Los Angeles, USA. 2012.
  • Yin NO, Kwek XY, Naylynn TM, Khairunnisa K, Moe KT. (2012) Nuclear factor (NF)-kappaB is regulated by NADPH oxidase-mediated reactive oxygen species in human cardiomyocytes. SingHealth Duke-NUS Scientific Congress 2012, 3-4 Aug 2012, Raffles City Convention Centre, Singapore. 2012.
  • Naylynn TM, Khairunnisa K, Yin NO, Kwek XY, Moe KT. (2012) Differential expression of adipocytokines in perivascular adipose tissue and subcutaneous adipose tissue of diet-induced obese mice (DIO) model. SingHealth Duke-NUS Scientific Congress 2012, 3-4 Aug 2012, Raffles City Convention Centre, Singapore. 2012.
  • Khairunnisa K, Naylynn TM, Yin NO, Kwek XY, Moe KT. (2012) In vivo and in vitro molecular mechanism of statin in attenuation of chronic inflammation-induced cardiac dysfunction and fibrosis. SingHealth Duke-NUS Scientific Congress 2012, 3-4 Aug 2012, Raffles City Convention Centre, Singapore. 2012.
  • Naylynn TM, Khairunnisa K, Yin NO, Kwek XY, Moe KT. (2012) A-769662, a novel AMP-activated protein kinase activator, attenuates TNF-a-induced ventricular remodelling. SingHealth Duke-NUS Scientific Congress 2012, 3-4 Aug 2012, Raffles City Convention Centre, Singapore. 2012.
  • Yin NO, Wutyi MA, Khairunnisa K, Naylynn TM, Moe KT. (2011) Chronic inflammation in perivascularadipose tissue induce vascular remodeling. Singapore General Hospital Annual Scientific Meeting, 8-9 April 2011, Singapore General Hospital, Singapore. 2011.
  • Wutyi MA, Khairunnisa K, Yin NO, Naylynn TM, Moe KT. (2011) Tumor necrosis factor-alpha-induced chronic inflammation in the heart leads to cardiac fibrosis. Singapore General Hospital Annual Scientific Meeting, 8-9 April 2011, Singapore General Hospital, Singapore. 2011.
  • Naylynn TM, Yin NO, Wutyi MA, Khairunnisa K, Moe KT. (2011) Association of NADPH oxidasep22phox C242T and A-930G polymorphisms with plasma nitrotyrosine, a biomarkerof oxidative stress, and hypertension. Singapore General Hospital Annual Scientific Meeting, 8-9 April 2011, Singapore General Hospital, Singapore. 2011.
  • Khairunnisa K, Naylynn TM, Wutyi MA, Yin NO, Moe KT. (2011) Fluvastatin attenuates chronic inflammation-associated cardiac fibrosis via downregulation of NADPH oxidase4. Singapore General Hospital Annual Scientific Meeting, 8-9 April 2011, Singapore General Hospital, Singapore. 2011.
  • Khairunnisa K, Yacui G, Atan MS, Moe KT, Liew R. (2011) Omega-3 polyunsaturated fattyacids counteract the effects of tumor necrosis factor alpha induced atrial fibrosis and alter connexion-40 expression in mice. European Heart Rhythm Association EHRA, EUROPACE, 2011, 26-29 June 2011, Madrid, Spain. 2011.
  • Moe KT, Wong P, Koh TH, Wong MC. (2010). An activation mechanism of nuclear factor-kappaB by NADPH oxidase. Arteriosclerosis, Thrombosis, and Vascular Biology, American Heart Association Annual Scientific Meeting. 8-10 April 2010, Hilton Union Square, San Francisco, California, USA. 2010.
  • Yin NO, Naylynn TM, Wong P, Koh TH, Wong MC, Moe KT. (2010). Tumor necrosis factor--induced upregulation of IL-1β and IL-6 is mediated by NADPH oxidase. Singapore Cardiac Society Annual Scientific Meeting 2010, 27-28 March 2010, Grand Copthorne Waterfront Hotel, Singapore. 2010.
  • Naylynn TM, DeSilva DA, Yin NO, Woon FP, Chang HM, Chen C, Moe KT, Wong MC. (2010). Endothelial Nitric Oxide synthase gene polymorphisms, haplotypes and risks of acute ischemic stroke. SingHealth Duke-NUS Scientific Congress 2010, Singapore, 15-16 Oct 2010, Suntec City, Singapore. 2010.
  • Khairunnisa K, Naylynn TM, Yin NO, WutYi MA, Wong P, Wong MC, Moe KT. (2010) Fluvastatin Ameliorates Tumor Necrosis Factor (TNF) α-Induced Cardiac Remodeling via Activation of AMP-Activated Protein Kinase. SingHealth Duke-NUS Scientific Congress 2010, Singapore, 15-16 Oct 2010, Suntec City, Singapore. 2010.
  • WutYi MA, Naylynn TM, Khairunnisa K, Yin NO, Wong P, Wong MC, Moe KT. (2010). NADPH (NOX) 4 Mediates Tumor Necrosis Factor ( TNF )-α-Induced Renal Fibrosis. SingHealth Duke-NUS Scientific Congress 2010, Singapore, 15-16 Oct 2010, Suntec City, Singapore. 2010.
  • Yin NO, Naylynn TM, Khairunnisa K, Wutyi MA, Wong P, Wong MC, Moe KT. (2010). Tumor Necrosis Factor (TNF)-α-Induced Nuclear Factor (NF)-κB Activation By NADPH Oxidase. SingHealth Duke-NUS Scientific Congress 2010, Singapore, 15-16 Oct 2010, Suntec City, Singapore. 2010.
  • Moe KT, Wong P, Koh TH, Wong MC. (2009) Nox2 and Nox4 mediate tumor necrosis factor--induced ventricular remodeling. Basic Cardiovascular Sciences Conference (BCVS 2009), 20-23 July, The Ritz-Carlton, Lake Las Vegas, Nevada, USA. 2009.
  • Gu Y, Le TT, Atan MSBM, Lim KK, Shim W, Wong P, Moe KT. (2009) Heterogeneity of left ventricular regional radial and circumferential strains in a baseline mice heart model. 17th Annual Scientific Meeting, Asia Pacific Cardiology Conference (APCC 2009), 20-23 May, Kyoto International Conference Center, Kyoto, Japan. 2009.
  • Atan MSBM, Gu Y, Khoo KK, Iskandar MFB, Lim S, Yin NO, Shim SN, Wong EH, Moe KT. (2009) Hydrogen sulphide is pro-inflammatory in cardiac contractility. 18th Annual Scientific Meeting, Singapore General Hospital, Singapore. 2009.
  • Gu Y, Le TT, Atan MSBM, Shim W, Tan RS, Wong P, Moe KT. (2009) Heterogeneity of left ventricular regional radial and circumferential strains in a mouse heart model. 18th Annual Scientific Meeting, Singapore General Hospital, Singapore. 2009.
  • Gu Y, Le TT, Atan MSBM, Lim KK, Shim W, Tan RS, Wong P, Moe KT. (2009) Normal echocardiographic ranges of left ventricular functional parameters in healthy adult male mouse models. 20th Annual Scientific Meeting, Singapore Cardiac Society, 21-22 March 2009, Grand Copthorne Waterfront Hotel, Singapore. 2009.
  • Yin N, Lim S, Mohamed SA, Gu Y, NayLynn TM, Wong P, Koh T, Wong MC, Moe KT. (2009) Tumor necrosis factor-alpha induced cardiac remodeling is mediated by NADPH oxidase. 20th Annual Scientific Meeting, Singapore Cardiac Society, 21-22 March 2009, Grand Copthorne Waterfront Hotel, Singapore. 2009.
  • Lim S, Yin NO, Wong P, Koh TH, Wong MC, Moe KT. (2009) Novel transcription regulatory mechanism of human Nox4 gene in human aortic smooth muscle cells. 20th Annual Scientific Meeting, Singapore Cardiac Society, 21-22 March 2009, Grand Copthorne Waterfront Hotel, Singapore. 2009.
  • Moe KT, Wong P, Koh TH, Wong MC. (2008) Inhibition of PPAR- agonists on TNF--induced oxidative stress in human aortic smooth muscle cells by PPAR- dependent mechanism. Arteriosclerosis, Thrombosis and Vascular Biology Annual Conference (ATVB 2008), 16-18 April, Atlanta, GA, USA. 2008.
  • Lim S, Wong P, Koh TH, Wong MC, Moe KT. (2008) Inhibition of PPAR- agonists on TNF- induced oxidative stress in human aortic smooth muscle cells by PPAR- dependent mechanism, 20th Annual Scientific Meeting, Singapore Cardiac Society, 22-23 March 2008, Grand Copthorne Waterfront Hotel, Singapore. 2008.
  • Saw MS, Wong P, Koh TH, Wong MC, Moe KT. (2008) Seropositivity of Chlamydia pneumoniae is associated with acute ischemic stroke, 20th Annual Scientific Meeting, Singapore Cardiac Society, 22-23 March 2008, Grand Copthorne Waterfront Hotel, Singapore. 2008.
  • NyeinNyein TD, Wong P, Koh TH, Wong MC, Moe KT. (2008) Significant Association of Plasma homocysteine and C667T MTHFR polymorphism with Acute Ischemic Stroke, 20th Annual Scientific Meeting, Singapore Cardiac Society, 22-23 March 2008, Grand Copthorne Waterfront Hotel, Singapore. 2008.
  • Yin NO, Wong P, Koh TH, Wong MC, Moe KT. (2008) NADPH oxidase p22phox and plasma nitrotyrosine, a biomarker of oxidative stress are associated with hypertension, 20th Annual Scientific Meeting, Singapore Cardiac Society, 22-23 March 2008, Grand Copthorne Waterfront Hotel, Singapore. 2008.
  • Moe KT, Sor LM, Woon FP, DeSilva DA, Chen CP, Wong P, Koh TH, Kingwell B, Wong MC, Chin-Dusting J. (2007) Positive Association of C667T Methylenetetrahydrofolate Reductase Gene Polymorphism with Acute Ischemic Stroke. Arteriosclerosis, Thrombosis and Vascular Biology Annual Conference (ATVB 2007), 19-21 April, The Palmer House Hilton, Chicago, IL, USA. 2007.
  • Moe KT, Sor LM, Wong P, Koh TH, Wong MC, Dusting G. (2007) JNK signaling mediates TNF- induced oxidative stress and Nox4 upregulation in human aortic vascular smooth muscle cells. 16th Singapore General Hospital Scientific Meeting, 27-28 April 2007, Singapore. 2007.
  • Min MM, Moe KT, Wong P, Koh TH, Wong MC. (2007) Lipopolysaccharide induced oxidative stress is mediated by NADPH oxidase in human vascular endothelial cells. Singapore General Hospital 16th Annual Scientific Meeting, 27-28 April 2007, Singapore. 2007.
  • Sor LM, Wong MC, Moe KT. (2007). Association of endothelial nitric oxide synthase gene polymorphisms with acute ischemic stroke in a Singapore population. Singapore General Hospital 16th Annual Scientific Meeting, 27-28 April 2007, Singapore. 2007.
  • Sor LM, Wong P, Moe KT, Koh TH, Wong MC. (2007) Association of Polymorphisms in MTHFR and NOS3 genes with Acute Ischemic Stroke. Singapore Cardiac Society 19th Annual Scientific Meeting, 17-18 March, Raffles City Conventional Centre, Singapore. 2007.
  • Moe KT, Sor LM, Wong P, Koh TH, Wong MC, Dusting G. (2007) JNK signaling mediates TNF-α induced oxidative stress and Nox4 upregulation in human aortic vascular smooth muscle cells. Singapore Cardiac Society 19th Annual Scientific Meeting, 17-18 March, Raffles City Conventional Centre, Singapore. 2007.
  • Woon FP, DeSilva DA, Chen CPLH, Chang HM, Moe KT, Wong MC. The profile of metabolic syndrome among ethnic indian ischemic stroke patients and comparison with ethnic chinese patients. Int’l J of Stroke 2006;Vol. 1(Suppl 1):104. 2006.
  • Moe KT, Susanto AP, Firdhaosh M, Wang DA. (2006) Superoxide detection by chemiluminescence, fluroscence and sepectrophotometry mehods. ICBPE 2006 (International conference on biomedical, pharmaceutical engineering, 11-14 December, Orchard Hotel, Singapore. 2006.
  • Susanto AP, Firdhaosh M, Wang DA, Moe KT. (2006) Superoxide detection by chemiluminescence, fluroscence and sepectrophotometry mehods. NTU-SGH Graduate Student Symposium. 8 December, Singapore General Hospital Postgraduate Medical Institute. 2006.
  • Moe KT, Sor LM, Koh TH, Wong MC. (2006) TNF-alpha induces oxidative stress in human vascular smooth muscle via Nox4 isoform of NADPH oxidase Singapore General Hospital 15th Annual Scientific Meeting, 21-22 April, Singapore General Hospital, Singapore. 2006.
  • Sor LM, Moe KT, Wong MC. (2006) Endothelial nitric oxide synthase genotype association study in a Singapore population. 18th Annual Scientific Meeting, Singapore Cardiac Society, 26 March, Grand Corpthone Hotel, Singapore. 2006.
  • Moe KT, Jiang F, Wong MC, Dusting GJ. (2005) TNF-a induces oxidative stress in human vascular smooth muscle via Nox4 isoform of NADPH oxidase. High Blood Pressure Research Council Australia (HBPRCA) Annual Scientific Meeting. 7-9 Dec. Bio21 Molecular Science & Biotechnology Institute, Parkville, Melbourne, Australia. 2005.
  • Moe KT, Wong MC, Chin-Dusting J. (2005) Association of a variable number of tandem repeats in endothelial nitric oxide synthase gene with essential hypertension in Singaporeans. High Blood Pressure Research Council Australia (HBPRCA) Annual Scientific Meeting. 7-9 Dec. Bio21 Molecular Science & Biotechnology Institute, Parkville, Melbourne, Australia. 2005.
  • Moe KT, Lim ST, Wong P, Chua T, Koh TH, Wong MC, Chin-Dusting J. (2005) Essential hypertension in Singaporeans: endothelial nitric oxide synthase genotype association. Combined Scientific Meeting (CSM2005), 4-6 Nov, Raffles City Convention Centre, Singapore. 2005.
  • Moe KT, Chee R, Chin-Dusting J. (2005) The role of VEGF in the development of oedema caused by PPAR-gamma agonists. 17 Annual Scientific Meeting, Singapore Cardiac Society, 26-27 March, The Regent, Singapore. 2005.
  • Moe KT, Aulia S, Chua YL, Koh TH, Wong MC, Dusting G. (2005) NADPH oxidase Nox4 mediates TNF-a-induced oxidative stress in vascular smooth muscle cells. 17 Annual Scientific Meeting, Singapore Cardiac Society, 26-27 March, The Regent, Singapore. 2005.
  • Moe KT, Aulia S, Chua YL, Koh TH, Wong MC, Dusting G. (2005) Isoform specific NADPH oxidase mediated oxidative stress in response to tumor necrosis factor-alpha. International congress on complementary and alternative medicine (ICCAM). 26-28 February. Raffles City Convention Centre, Singapore. 2005.
  • Moe KT, Chua HH, Chan EC, Tan YL, Koh TH, Wong MC, Dusting G. (2004) Tumor necrosis factor-alpha-induced human embryonic kidney cells-oxidative stress is mediated by NADPH oxidase. SingHealth Scientific Meeting 2004, 15-17 Oct 2004, Shangri-La Singapore. 2004.
  • Moe KT, Chee R, Chin-Dusting J. (2004) The role of VEGF in the development of oedema caused by PPAR-gamma agonists. SingHealth Scientific Meeting 2004, 15-17 Oct 2004, Shangri-La Singapore. 2004.
  • Goh ALH, Moe KT, Chen XQ, Tan KSW. (2004) Characterization and DNA damage induced expression of MRE11 recombination protein in Plasmodium falciparum. In Life Sciences in Singapore: Health and Disease. 5th Combined Annual Scientific Meeting, 12-14 May, National University of Singapore, Singapore. 2004.
  • Goh ALH, Moe KT, Chen XQ, Tan KSW. (2004) Identification and Characterization of an MRE11 homologue in Plasmodium falciparum. Molecular Approaches to Malaria, 1-5 February, Lorne, Australia. 2004.
  • Choo KW, Tham L, Tan TS, Kong WM, Moe KT, Tan P, Wong K. (2003) Microarray Analysis Tools, Singapore Microarray Meeting (SSM), 11-18 January, National University of Singapore, Singapore. 2003.
  • Beuerman RW, Cha L, Moe KT. (2001) Understanding how atropine inhibits the development of myopia. BioMedical Asia 2001, 19-21 September, Singapore International Convention and Exhibition Centre, Singapore. 2001.
  • Beuerman RW, Moe KT, Tan D. (2001) Molecular analysis of atropine inhibition of myopia. First Singapore Eye Research Institute International Meeting & 3rd Singapore National Eye Research Meeting, 27-30 September, Singapore. 2001.
  • Beuerman RW, Tan D, Moe KT. (2001). Microarray analysis of gene expression in primary pterygia. First Singapore Eye Research Institute International Meeting & 3rd Singapore National Eye Research Meeting, Singapore. 27-30 September. 2001.
  • Barathi A, Zhiliang J, Chew J, Moe KT, Beuerman RW. (2001) Multiple gene expression examined by Real-time PCR following an anterior keratectomy wound. First Singapore Eye Research Institute International Meeting & 3rd Singapore National Eye Research Meeting, Singapore. 27-30 September. 2001.
  • Liu Y, Lew Q, Moe KT, Beuerman RW, Yap EP. (2001) One-step PCR amplification and sequence analysis of entire rhesus monkey mitochondrial genomes, First Singapore Eye Research Institute International Meeting & 3rd Singapore National Eye Research Meeting, Singapore. 27-30 September. 2001.
  • Moe KT, Beuerman RW, Ji ZI, Zhou L, Barathi A. (2001) Topical atropine modulates the regulation of message for muscarinic receptors in mouse ocular tissue. The Association for Research in Vision and Ophthalmology, 29th April–4th May, Fort Lauderdale, FL. 2001.
  • Moe KT, Beuerman RW, Barathi A. (2001) Patterns of gene expression associated with normal scleral growth in the rabbit. Singapore National Eye Research Meeting, 2000, 4th August Singapore International and Exhibition Centre. 2001.
  • Ji ZL, Moe KT, Barathi A, Beuerman RW. (2000) Variation in scleral housekeeping genes expression in postnatal rabbits. Singapore National Eye Research Meeting, 4th August Singapore International and Exhibition Centre. 2000.
  • Barathi A, Tong L, Chan B, Carkeet A, Moe KT, Beuerman RW. (2000) The Onset of cycloplegia in Albino rabbits. Singapore National Eye Research Meeting, 4th August Singapore International and Exhibition Centre. 2000.
  • Barathi A, Tong L, Chan B, Carkeet A, Moe KT, Beuerman RW. (2000) Autorefraction and retinoscopy in Albino rabbits. . Singapore National Eye Research Meeting, 4th August Singapore International and Exhibition Centre. 2000.
  • Barathi A, Moe KT, Beuerman RW. (2000) Dimensional growth of the rabbit eye. Singapore National Eye Research Meeting, 4th August Singapore International and Exhibition Centre. 2000.
  • Moe KT, Beuerman RW, Barathi A. (2000) Patterns of gene expression associated with normal scleral growth in the rabbit. Conference on Myopia, 7th –9th July, Boston, Massachusetts. 2000.
  • Moe KT, Beuerman RW, Barathi A. (2000) Gene expression and scleral growth in the rabbit The Association for Research in Vision and Ophthalmology, 30th April–5th May, Fort Lauderdale, FL. 2000.
  • Moe KT, Chew SJ. (1999) Effect of transforming growth factor-beta2 (TGF-2) on albumin synthesis in rabbit vitreous humor The Association for Research in Vision and Ophthalmology, 9th –14th May, Fort Lauderdale, FL. 1999.
  • Moe KT, Chew SJ, Cheng HM. (1998) Proteinase activity in ocular tissue of New Zealand White albino rabbits 2nd Annual Research Meeting in Ophthalmology and Visual Sciences, Department of Ophthalmology, Tan Tock Seng Hospital, 4th April. 1998.
  • Moe KT, Singh M, Ho LC, Tan SW, Chen XQ, Yap EH. (1997) Immune response in experimental Blastocystis hominis infection in rats. 33rd Annual Scientific Seminar, Malaysian Society of Parasitology and Tropical Medicine, 14-15th March, Vistana Hotel, Kuala Lumpur, Malaysia. 1997.
  • Moe KT, Singh M, Ho LC, Tan SW, Chen XQ, Yap EH. (1997) Experimental Blastocystis hominis infection in laboratory mice. Annual Scientific Meeting, Singapore Society for Microbiology and Biotechnology, York Hotel, 25th January, Singapore. 1997.
  • Tan SW, Singh M, Ho LC, Moe KT, Chen XQ, Yap EH. (1997) Emerging Protozoan Diseases. In Microbiology in Singapore: From the past into the future; Singapore Society for Microbiology and Biotechnology. Annual Scientific Meeting, 25th January 1997, Singapore. 1997.
  • Singh M, Ho LC, Moe KT, Tan SW, Yap EH. (1996) Blastocystis: A peep into the Pandora's box. In Proceedings of the Forth International Congress of Tropical pediatrics, 7-11 July, Shangri-La Hotel, Kuala Lumpur, Malaysia. 1996.
  • Tan SW, Singh M, Yap EH, Ho LC, Moe KT, Chen XQ. (1996) Studies on Blastocystis hominis using monoclonal antibodies. 32nd Annual Scientific Seminar, Malaysian Society of Parasitology and Tropical Medicine. 29-30th March, Perdanasiswa, University Malaya, Kuala Lumpur, Malaysia. 1996.
  • Chen XQ, Singh M, Ho LC, Moe KT, Tan SW, Yap EH. (1996) A report on Blastocystis in rodents. 32nd Annual Scientific Seminar, Malaysian Society of Parasitology and Tropical Medicine. 29-30th March, Perdanasiswa, University Malaya, Kuala Lumpur, Malaysia. 1996.
  • Moe KT, Singh M, Howe J, Ho LC, Tan SW, Chen XQ, Yap EH. (1996) Structure, viability and infectivity of faecal cysts of Blastocystis hominis. 32nd Annual Scientific Seminar, Malaysian Society of Parasitology and Tropical Medicine. 29-30th March, Perdanasiswa, University Malaya, Kuala Lumpur, Malaysia. 1996.
  • Tripathi M, Zhang C, Singh BK, Sinha RA, Thu MK, De Silva DA, Yen PM. Vitamin B12 and Folate Ameliorates Hyperhomocysteinemia Induced ER Stress via Restoration of Autophagic Flux. In: Asia Pacific Stroke Conference 2015. 2015, Kuala Lumpur, Malaysia: Karger.