CHY8824 : Methods and Techniques for Drug Chemistry

Semester 1 Credit Value: 10
Semester 2 Credit Value: 10
ECTS Credits: 10.0


To increase understanding of key synthetic organic transformations; to develop knowledge of spectroscopic techniques for the study of organic molecules; to use spectroscopic data for structure determination of organic molecules; to recognise practical constraints in the design of synthetic procedures; to develop skills in key experimental techniques, including chromatography.

Outline Of Syllabus

• Lectures on analytical techniques (1H, 13C NMR, MS, IR, chromatography
• Lectures and workshops on synthetic transformations
• Laboratory course on experimental techniques and multi-step syntheses
• Structure determination using spectroscopic data

Teaching Methods

Teaching Activities
Category Activity Number Length Student Hours Comment
Guided Independent StudyAssessment preparation and completion46:0024:00Writing practical report (4 experiments)
Guided Independent StudyAssessment preparation and completion110:0010:00Coursework exercises
Scheduled Learning And Teaching ActivitiesLecture581:0058:00Lectures on chemical structure, synthetic transformations and mechanisms
Scheduled Learning And Teaching ActivitiesPractical401:0040:0010h over 2 days per week for 4 weeks
Scheduled Learning And Teaching ActivitiesSmall group teaching122:0022:001 and 2h workshops, organic assessments
Guided Independent StudyIndependent study146:0046:00Background reading and practice past examination questions
Jointly Taught With
Code Title
CHY1101Basic Organic Chemistry
Teaching Rationale And Relationship

Lectures convey the key concepts and factual data. Seminars allow focussed discussion and expansion of material from the lectures and from BSc. Group learning allows individual and team application of the knowledge gained through the lectures and seminars
Laboratory classes allow multiple experimental techniques to be practised and understand how this relates to the lecture/seminar material

Assessment Methods

The format of resits will be determined by the Board of Examiners

Other Assessment
Description Semester When Set Percentage Comment
Practical/lab report2M40Laboratory Report (covering 4 individual experiments) approx. 12 pages including appendices
Essay2M30Spectroscopy assignment - approx. 3 pages including appendices
Written exercise1M30Organic tests (3x 10% each)
Formative Assessments
Description Semester When Set Comment
Prob solv exercises1MPractice problem sheets are used in the tutorials (7) and the lectures (12)
Assessment Rationale And Relationship

Individual knowledge is assessed through coursework in semesters 1 and 2, the reduced time constraints of coursework allows more diverse and hence realistic synthetic problems to be undertaken.
Laboratory work and problem solving skills are assessed through the coursework in semester 2, coursework allows a more realistic problem to be set as industry would not place rigorous time constraints.
Assessment of proficiency in safety, experimental techniques and report writing is through the laboratory report, which comprises of the write-up of 4 individual experiments.

Reading Lists