CHY8828 : Bioactive Natural Products
- Offered for Year: 2019/20
- Module Leader(s): Professor Bernard Golding
- Lecturer: Dr Cristina Navarro Reguero, Dr Agnieszka Bronowska
- Owning School: Natural and Environmental Sciences
- Teaching Location: Newcastle City Campus
Semester 2 Credit Value:
To equip students with a knowledge of natural products obtained from a range of sources including plants and marine organisms with the emphasis on the medicinal properties of substances; to describe extraction techniques and how these influence the chemical composition of the extract; to define compound classes of active constituents; to delineate the biosynthesis of selected compound classes; to show how selected compounds can be synthesised including a description of some industrial syntheses; to equip students with a basic understanding of how bioactive natural products are believed to work; to place natural products in the wider context of bioactive compounds.
Outline Of Syllabus
1-2 Introduction - Classes of natural products; isolation of natural products
3-4 Isolation, structure determination and synthesis of selected natural products
5-6 The alkaloids morphine, quinine and cocaine
7 Colchicine, galanthamine
8 Marine natural products
9-10 Aromatic natural products; fatty acid biosynthesis; polyketides;
11-12 Shikimic acid; terpenes
13-14 Steroids, prostaglandins and thromboxanes
+ plus 6 workshops
|Scheduled Learning And Teaching Activities||Lecture||21||1:00||21:00||N/A|
|Guided Independent Study||Assessment preparation and completion||1||15:00||15:00||Preparation and completion of computer assessment|
|Guided Independent Study||Assessment preparation and completion||21||0:30||10:30||Revision for end of semester examination|
|Guided Independent Study||Assessment preparation and completion||1||2:00||2:00||End of semester examination|
|Guided Independent Study||Independent study||1||51:30||51:30||Study course handouts and background reading|
Jointly Taught With
|CHY2102||Bioactive Natural Products|
Teaching Rationale And Relationship
Lectures convey the key concepts and factual data and introduce problem solving skills. Seminars allow application of the concepts introduced in the lectures.
The format of resits will be determined by the Board of Examiners
|CHY2102||Bioactive Natural Products||2||N/A|
Assessment Rationale And Relationship
The formal exam allows the understanding of the concepts; application/problem solving based on the concepts to be assessed.
The assignment will allow students to retrieve information, whilst using initiative and gaining computer literacy skills.