CHY8828 : Bioactive Natural Products

Semester 2 Credit Value: 10
ECTS Credits: 5.0


To equip students with a knowledge of natural products obtained from a range of sources including plants and marine organisms with the emphasis on the medicinal properties of substances; to describe extraction techniques and how these influence the chemical composition of the extract; to define compound classes of active constituents; to delineate the biosynthesis of selected compound classes; to show how selected compounds can be synthesised including a description of some industrial syntheses; to equip students with a basic understanding of how bioactive natural products are believed to work; to place natural products in the wider context of bioactive compounds.

Outline Of Syllabus


1-2 Introduction - Classes of natural products; isolation of natural products
3-4 Isolation, structure determination and synthesis of selected natural products
5-6 The alkaloids morphine, quinine and cocaine
7 Colchicine, galanthamine
8 Marine natural products
9-10 Aromatic natural products; fatty acid biosynthesis; polyketides;
11-12 Shikimic acid; terpenes
13-14 Steroids, prostaglandins and thromboxanes
+ plus 6 workshops

Teaching Methods

Teaching Activities
Category Activity Number Length Student Hours Comment
Scheduled Learning And Teaching ActivitiesLecture211:0021:00N/A
Guided Independent StudyAssessment preparation and completion115:0015:00Preparation and completion of computer assessment
Guided Independent StudyAssessment preparation and completion210:3010:30Revision for end of semester examination
Guided Independent StudyAssessment preparation and completion12:002:00End of semester examination
Guided Independent StudyIndependent study151:3051:30Study course handouts and background reading
Jointly Taught With
Code Title
CHY2102Bioactive Natural Products
Teaching Rationale And Relationship

Lectures convey the key concepts and factual data and introduce problem solving skills. Seminars allow application of the concepts introduced in the lectures.

Assessment Methods

The format of resits will be determined by the Board of Examiners

Description Length Semester When Set Percentage Comment
PC Examination1202A75N/A
Exam Pairings
Module Code Module Title Semester Comment
CHY2102Bioactive Natural Products2N/A
Other Assessment
Description Semester When Set Percentage Comment
Computer assessment2M25N/A
Assessment Rationale And Relationship

The formal exam allows the understanding of the concepts; application/problem solving based on the concepts to be assessed.
The assignment will allow students to retrieve information, whilst using initiative and gaining computer literacy skills.

Reading Lists