Postgraduate

Modules

Modules

MMB8031 : Developmental Genetics

Semesters
Semester 1 Credit Value: 20
ECTS Credits: 10.0

Aims

The primary aims of this module are to:

1. introduce students to the genetic mechanisms controlling developmental processes, and to illustrate their importance for identifying and evaluating inherited disorders in humans.

2. provide the students with a comprehensive knowledge about the latest research technologies applied to the analysis and understanding of gene functions in the developing mammalian embryo.

Outline Of Syllabus

This module will teach fundamental principles of Developmental Genetics and will explain how they impact on medically relevant research areas. The lectures will include several elements (“Research Focus”) of topical research projects currently carried out by group leaders involved in teaching on this module.

Specifically, the module will consider:

•       The early developmental processes that regulate the establishment of the body plan.

•       How gene activities control the formation of “patterns.”

•       The genetic control regulating the development of major organ systems.

•       Key signalling pathways in development.

•       Human tissue-specific gene expression analysis and digital atlases.

•       Syndromes associated with disrupted functions of key developmental control genes.

•       Practical approaches to investigate gene function in vivo and their application in medical genetics.

•       The importance of developmental processes to the therapeutic potential of embryonic and somatic stem cells.

Teaching Methods

Module leaders are revising this content in light of the Covid 19 restrictions.
Revised and approved detail information will be available by 17 August.

Assessment Methods

Module leaders are revising this content in light of the Covid 19 restrictions.
Revised and approved detail information will be available by 17 August.

Reading Lists

Timetable