NES8009 : Fundamentals of Cell and Molecular Biology
- Offered for Year: 2019/20
- Module Leader(s): Dr Ethan Hack
- Other Staff: Dr Martin Edwards
- Owning School: Natural and Environmental Sciences
- Teaching Location: Newcastle City Campus
|Semester 1 Credit Value:||10|
To survey the fundamentals of cell and molecular biology and introduce key methods used in research on these subjects. This module is intended for students taking Masters-level courses in biological subjects who have not undertaken degree-level study of cell and molecular biology or who need to refamiliarise themselves with these topics.
Outline Of Syllabus
Introduction: genes and cells.
Proteins: composition and structure.
Organisation of prokaryotic and eukaryotic cells.
Protein synthesis: transcription and translation mechanisms.
Principles of regulation of gene expression.
Genomes: prokaryotic, eukaryotic nuclear, mitochondrial, and plastid.
Essential techniques in molecular biology: DNA cloning, library screening, PCR, detection and measurement of gene expression, DNA sequencing.
Lab: fundamentals of recombinant DNA technology.
|Scheduled Learning And Teaching Activities||Lecture||17||1:00||17:00||Lecture follow-up|
|Guided Independent Study||Assessment preparation and completion||1||1:30||1:30||Final exam|
|Guided Independent Study||Assessment preparation and completion||17||0:30||8:30||Revision for final exam|
|Guided Independent Study||Assessment preparation and completion||6||1:00||6:00||Structured questions|
|Scheduled Learning And Teaching Activities||Lecture||17||1:00||17:00||N/A|
|Guided Independent Study||Directed research and reading||12||1:00||12:00||Directed reading|
|Scheduled Learning And Teaching Activities||Practical||3||4:00||12:00||N/A|
|Guided Independent Study||Independent study||1||26:00||26:00||Study of lectures; ReCap, Blackboard etc.|
Teaching Rationale And Relationship
The lectures review background, explain key concepts and outline illustrative examples. The final lecture is a revision session. The practicals give students hands-on experience, with supervision and guidance, with recombinant DNA technology and the use of computers to analyse DNA and protein sequences. Private study is necessary for students to absorb information presented in lectures, to deepen their knowledge and understanding through reading supporting material, and to complete the analysis of data from the practicals.
The format of resits will be determined by the Board of Examiners
|Written Examination||90||1||A||70||3 Multipart questions from 6, equal weighting|
|Practical/lab report||1||M||28||Structured questions|
|Written exercise||1||M||2||Practice exam|
Assessment Rationale And Relationship
The exam, assesses knowledge and understanding of the relevant subject material and the ability to integrate information from lectures and additional reading. A structured set of questions (deadline week 8) assesses students’ ability to produce, record and interpret data from experiments involving recombinant DNA technology. The exam practice (week 9) assesses students' progress in developing command of the course material and gives students the opportunity and incentive to develop their exam technique.
Study Abroad students may request to take their exam before the semester 1 exam period, in which case the format of the paper may differ from that shown in the MOF. Study Abroad students should contact the school to discuss this.