Faculty of Science, Agriculture & Engineering

Chemistry Mass-Spectrometry

Chemistry Mass-Spectrometry

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Overview

The Chemistry Mass-Spectrometry Laboratory was established in 2018, following investment of over £300k, to consolidate chemistry and chemical biology mass-spectrometry capability into a single facility. We provide Mass-Spectrometry analysis for isolated small organic and inorganic molecules (e.g. synthetic molecules, natural products, small peptides, drugs and drug precursors) as well as mixtures (e.g. reaction monitoring, biological metabolites).

Isolated small molecules can be studied directly by a range of Mass-Spectrometry techniques. We have a suite of mass analysers that can provide rapid low resolution mass, high resolution accurate mass, elemental composition and structural information via fragmentation analysis (MSn).

Small molecule mixtures are typically analysed using Liquid Chromatography Mass-Spectrometry (LC-MS), one of the most widespread and efficient analytical techniques for the separation and analysis of chemical mixtures. The Chemistry Mass-Spectrometry Laboratory employs modern UPLC-MS methods for the separation and detection of compounds in a wide range complex chemical and biological samples.

Additional liquid chromatography instrumentation is also available capable of normal and reverse phase separations (analytical and semi-preparative) with UV/vis, diode array and fluorescence detectors.

Drawing on our expert Mass-Spectrometry knowledge and access to a wide range of HPLC techniques, we are confident that we can develop small molecule analysis methods to fit your needs.

If you have questions about the SAgE Analytical Facility or would like to request a quote, contact us.

Services

Chemistry MS Facility

Applications

Staff

Dr Alex Charlton
Senior Analytical Technician

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Contact us

If you have questions about the SAgE Analytical Facility or would like to request a quote, contact us.