Faculty of Science, Agriculture & Engineering

Mass Spectrometry

Mass Spectrometry



 Mass-Spectrometry is a powerful analytical technique used to determine the molecular mass, elemental composition, and structure of a range of chemical compounds.

The SAgE Mass-Spectrometry Facility at Newcastle University, opened in 2018, is comprised of the Chemistry Mass-Spectrometry and Environmental Mass-Spectrometry laboratories. Focussing on the analysis of ‘Small Molecules’ (50-4000 Da), we can provide internal and external customers with Quantitative and Qualitative information for both isolated molecules or those present in a complex mixture. We are proud to offer a broad range of Mass-Spectrometry techniques including:

  • Separation – UPLC, HPLC, and GC
  • Ionisation - Electrospray Ionisation (ESI), Atmospheric Pressure Chemical Ionisation (APCI), Atmospheric Pressure Photo-Ionisation (APPI), Electron Ionisation (EI), Chemical Ionisation (CI), Rapid Evaporative Ionisation (REI-MS)
  • Mass Analysis – Triple Quadrupole (QqQ), Single Quadrupole, Ion Trap
  • High Resolution Mass Analysis - Quadrupole Time-of-Flight (QToF)

We have establised methods for a wide range of small molecule samples, such as:

  • Biological Samples – Small Metabolites, Microbial Lipids, and Natural Products
  • Chemical Samples – Small Organic and Inorganic Molecules, Drugs and Drug Precursors, Chemical Reaction Monitoring

If you have questions about the SAgE Analytical Facility or would like to request a quote, contact us.