Sir Joseph Swan Centre for Energy Research

Staff Profile

Dr Eimer Tuite

Senior Lecturer in Biophysical Chemistry

Background

The Tuite Lab works at the interface of life and physical sciences, applying chemical and physical tools to biological, materials, and environmental problems.
We have particular interests in the chemistry, dynamics, and recognition of DNA in the context of nano-assembly, synthetic biology, molecular diagnostics, and photodynamic therapy. Another research line involves optical spectroscopy, photophysics, photochemistry, and photobiology.

Together with the Pike Group, we form the Bioinspired Molecular Engineering Group.
In April 2021, assisted by Innovate UK, we jointly spun out
NunaBio Ltd to provide provide DNA solutions for microbial detection and biochemical research.

Background

My undergraduate and postgraduate studies were at Trinity College Dublin. In 1992, I completed my PhD in the School of Chemistry with Prof John Kelly on photosensitized damage of DNA. I then moved to Gothenburg on the Swedish west coast for postdoctoral work with Prof Bengt Norden at Chalmers University of Technology in the field of biomolecular recognition, and subsequently accepted an Assistant Professorship there. In 2000 I moved to a lectureship at Newcastle where I have continued to expand my research in Biophysical Chemistry.

Qualifications and Previous Positions

1987: BA (4 yrs) in Natural Sciences (Chemistry with Physics and Maths), Trinity College Dublin (Cocker Medal)
1992: PhD in Chemistry with John Kelly, Trinity College Dublin
1990-1991: President, Trinity College Dublin (DU) Graduate Students' Union.

1993-1995: Wenner-Gren/SI Research Fellow with Bengt Norden, Chalmers University of Technology, Göteborg
1995-1996: EU Marie Curie Research Fellow with Bengt Norden, Chalmers University of Technology, Göteborg
1996-2000: Assistant Professor in Biophysical Chemistry, Chalmers University of Technology, Göteborg
1998:          Docent in Biophysical Chemistry, Chalmers University of Technology, Göteborg

External Scientific Service

EPSRC Peer Review College (2002-2005, 2006-2009, 2010-2016, 2016- )
BBSRC Pool of Experts (2009-2013)
     – TRDF, Committee C, and ALERT panels (2009-2017)
EU Evaluation Expert (2010- ; FP7 & H2020)
     – Life Science and Chemistry: MSCA IF/ITN/RISE/WIDESPREAD; COST
ERC Evaluation Expert (2014-2020)
     – Life Science Starter Grants panel (LS7 - Diagnostics, Therapies, Public Health)
FCT (Portugal) Evaluation Expert (2017- )
    – Life Science Panels

Other

Taekwondo, tennis, pilates, yoga, SUP

 

Teaching

Undergraduate Modules

CHY1200 General Chemistry: module leader, lecturer
CHY1510 General Chemistry: labs
CHY1510 Introductory Physical Chemistry: labs
CHY2201 Physical Chemistry - Kinetics: module leader, lecturer
CHY2510 Physical Chemistry: labs
CHY8428 Energy and Materials - Biophysical Chemistry: module leader and lecturer

Stage 3 Literature project

I offer projects on topics in nanoscience, imaging, diagnostics, and biomedicine.

MChem and MSc Projects

I offer projects to masters students on biophysics, photophysics and photochemistry of DNA/probe systems, and on DNA diagnostics.

Research

Research Grants

EU MSCA Research & Innovation Staff Exchange (RISE) Grant (#778001) 2018-2023
DNASURF: MOLECULAR DIAGNOSTICS THROUGH DNA MODIFICATION AND INTERFACIAL ENGINEERING

DNASURF Project Website
Looking forward to working with excellent colleagues in Dublin, Birmingham, Vitoria-Gasteiz (Basque Country), Jerusalem, Singapore, Sapporo, Sydney, Melbourne, and Provo (Utah).

Research Topics

  • Spectroscopic and biophysical studies of drug interactions with DNA and analogues (especially phenothiazines, cyanines, acridines, ruthenium complexes) including chiral, sequence, and structural recognition.
  • Mechanisms of photocleavage of DNA, including metal complex and cyanine photosensitizers.
  • Electron and energy transfer mediated by DNA and PNA for structural and dynamic studies of nucleic acids, especially with metal complexes, light harvesting, and conductivity investigations.
  • Nucleic acid-based assembly of nanoscopic architectures.
  • Quantum dots, SERS, and near-field microscopy.
  • Enzymatic extension methods for synthesis of modified DNA.

Chemical Nanoscience Labs Research

Publications (Scopus)

47 : Peer-Reviewed Papers and Reviews
27 : h-index
3 : patent applications

Google Scholar: Eimer M Tuite
ResearcherID:
A-4356-2012
ORCID:
0000-0002-2805-4858

Publications