BIO1020 : Genetics and Evolution
- Offered for Year: 2019/20
- Module Leader(s): Dr Tahar Taybi
- Lecturer: Dr Colin Tosh, Dr Ankush Prashar, Dr Emmi Hall, Dr Maxim Kapralov
- Owning School: Natural and Environmental Sciences
- Teaching Location: Newcastle City Campus
|Semester 2 Credit Value:||20|
To develop a basic understanding of genetic principles and their application in biology.
To give an introduction to the concepts and principles of inheritance of genetic characters, their recombination and linkages.
To give a basic understanding of the genetic code and the replication of DNA.
To outline how genes are expressed into proteins, via transcription and translation.
To review the methods used to study the genetic material and how these methods are used in different applications.
To review the evidence for evolution from the fossil record, earth history, and comparisons of living organisms in terms of structure, function and genetic constitution.
To outline mechanisms for evolution, especially in terms of artificial and natural selection and genetic drift.
To explore the observational and experimental evidence for the role of these mechanisms in causing evolution.
This module provides the basis for other modules.
Outline Of Syllabus
• Introduction to the module: key elements of genetics and evolution.
• Mitosis and meiosis: Cell cycle and chromosome replication.
• Recombination and segregation, the basis of variability.
• Transmission (Mendelian) Genetics: Key concepts and vocabulary.
• Molecular genetics: Introduction to molecular genetics, DNA structure, Genomes, packaging of DNA, DNA replication.
• DNA-RNA-Protein: The process of protein synthesis, transcription, structure of RNA, RNA processing in eukaryotes, Architecture of eukaryotic genes, functional importance of processing events.
• Translation: Ribosome structure, RNA molecules, mechanism of protein synthesis.
• Regulation of gene expression, Eukaryotic regulation.
• Analytical techniques in molecular genetics and Polymerase Chain Reaction (PCR).
• Recombinant DNA technology: Components of the technology and applications.
• Genome size and evolution.
• The origin and evolutionary characteristics of chloroplasts and mitochondria..
• Molecular clocks and molecular evolution.
• Molecular evolution and phylogeny.
• Phylogenetic trees.
• Mass extinctions, Earth history.
• Human evolution.
• Evolution by selection and drift.
• Natural selection.
• Causes of evolution, adaptive radiation, rates of evolution.
• The nature of variation and evolution without selection.
• Special types of selection and constraints on adaptation
• Speciation mechanisms.
• Sympatric speciation.
|Scheduled Learning And Teaching Activities||Lecture||30||1:00||30:00||N/A|
|Guided Independent Study||Assessment preparation and completion||1||6:00||6:00||Completion of workshop problem solving exercise (Blackboard)|
|Guided Independent Study||Assessment preparation and completion||1||6:00||6:00||Completion of computer test (Blackboard) Evolution test|
|Guided Independent Study||Assessment preparation and completion||2||6:00||12:00||Completion of Lab report worksheets and computer test|
|Guided Independent Study||Assessment preparation and completion||1||2:00||2:00||Final exam|
|Guided Independent Study||Assessment preparation and completion||30||0:30||15:00||Revision for final exam|
|Guided Independent Study||Directed research and reading||30||1:00||30:00||Post-lecture directed reading|
|Scheduled Learning And Teaching Activities||Practical||4||3:00||12:00||N/A|
|Guided Independent Study||Independent study||30||1:00||30:00||Lecture follow- up|
|Guided Independent Study||Independent study||2||3:00||6:00||Data analysis /problem solving|
|Guided Independent Study||Independent study||1||21:00||21:00||Consolidation of knowledge and skills|
|Guided Independent Study||Independent study||30||1:00||30:00||Study of ReCap, Blackboard etc. to enhance understanding|
Teaching Rationale And Relationship
The lectures introduce the vocabulary of genetics and describe the principles and practices involved in cytogenetics, transmission genetics, molecular genetics and explain the key mechanisms of evolution and how to study them. The workshop sessions encourages students to apply their knowledge of transmission genetics in solving genetics problems and understanding the basic mechanisms of evolution. Students are encouraged to use the Life website to benefit from the support material provided including tests and animated tutorials. Students are steered towards readings centred on and around the Life textbook (Purves et al.). The practical sessions will help students to understand the concepts, techniques and methods of molecular genetics in greater detail and learn how to implement some of them by allowing them to complete practical tasks and watch demonstrations; the evolution lab which uses the museum resources aims at demonstrating the results of key evolutionary processes.
The format of resits will be determined by the Board of Examiners
|Practical/lab report||2||M||15||Lab Assessment - Report (max. 2000 words)|
|Computer assessment||2||M||15||Computer Test|
|Computer assessment||2||M||Computer test (Blackboard) Evolution test|
|Prob solv exercises||2||M||Workshop Problem solving exercise (Blackboard)|
Assessment Rationale And Relationship
The formative workshop exercise gives students a chance to test their problem solving skills during the semester. The examination and computer tests (both formative and summative) test the knowledge and understanding of information delivered in the lectures, workshop and practicals. The lab report assesses the skills of data collection, analysis and reporting.