BMS2002 : Cell Biology and Disease

Semester 1 Credit Value: 20
ECTS Credits: 10.0


Through this module the student will gain greater understanding of aspects of Cell Biology focusing on post-translational events and how cellular events lead to normal tissue function or disease development. Lectures, small groups and practical work will be used to develop a greater understanding of how the mechanisms within individual cells and between cells impact on tissues and therefore the organism. The module will employ a case study approach looking at the impact of mechanistic dysfunction on various conditions such as diabetes, heart disease and cancer.

Outline Of Syllabus

The students will study the following cellular processes:
•       Proteins: post-translational processing and trafficking,
•       Membrane transport and ion channels,
•       Extracellular matrix,
•       Cell Signalling,
•       Cell cycle.
Disease case studies will be used to illustrate the effect of dysfunction in each of these processes.

Teaching Methods

Teaching Activities
Category Activity Number Length Student Hours Comment
Scheduled Learning And Teaching ActivitiesLecture241:0024:00N/A
Scheduled Learning And Teaching ActivitiesPractical14:004:00N/A
Scheduled Learning And Teaching ActivitiesSmall group teaching11:001:00Students will present posters in powerpoint form to the group, supported by peer assessment
Scheduled Learning And Teaching ActivitiesSmall group teaching51:005:00Seminars
Guided Independent StudyIndependent study1166:00166:00N/A
Teaching Rationale And Relationship

Lectures will be used to provide new detailed information and illustrate the significance of normal and abnormal mechanisms using examples of common diseases (LO K1-3).
A case study approach will be used in seminars to enable students to discuss and gain a deeper understanding of the lecture material (LO K4, S2).
A laboratory-based practical will enhance the students competence in the laboratory and generate a suitable set of data that can be used for assessment purposes (LO S3)
Before and following the practical, two of the seminars will be used to introduce the students to academic posters and then form peer support groups to discuss poster design and their construction to help prepare the student for the assessment.
Students will be expected to use independent study time to read around the subject to gain a greater understanding of the topic (LO S1).

Assessment Methods

The format of resits will be determined by the Board of Examiners

Description Length Semester When Set Percentage Comment
Written Examination1201A70MCQ 50%. Essay 50% - 1 question from a choice of 2
Other Assessment
Description Semester When Set Percentage Comment
Practical/lab report1M15The students will construct an academic poster based on the practical they carry out in the module, equivalent word count <1000
Essay1M15Timed Essay 45 minutes
Formative Assessments
Description Semester When Set Comment
Computer assessment1MThe students will carry out a formative online activity to assess their understanding of the flow cytometry practical
Assessment Rationale And Relationship

There will be three assessments - a practical report, a timed essay and an exam.

The exam will have 70% weighting which will assess the students' knowledge and understanding. It will be made up of an MCQ and an essay question (one essay from a choice of two).

Practical Report
For the practical report (15%) the students will construct an academic poster to present the methodologies, findings and data analysis of the practical carried out

Timed Essay
The timed essay (15%) will be set to assess whether the students have made the link between the chosen case study and the theory, particularly addressing intended knowledge outcomes 3 and 4.

Reading Lists