BMS2012 : Clinical Immunology and Viral Pathogens

Semester 2 Credit Value: 20
ECTS Credits: 10.0


• To develop an appreciation of the part played by the immune system in a range of human diseases

•To build upon the students’ knowledge of basic virology and develop an understanding of the biology of pathogenic viruses

Outline Of Syllabus

Clinical Immunology Strand:
The module considers the role of the immune system in human disease. The first part of the module considers immunity in the context of infectious disease with particular reference to inflammation and immunodeficiency. The second part of the module considers how immune responses can cause disease with reference to allergic disease, autoimmunity, cancers of the immune system and transplantation. Finally the module describes the diagnostic techniques currently used in clinical immunology, immunosuppressive drugs and the potential of immunomodulation and immunotherapy in the treatment of a number of conditions.

Virology Strand:
Strand B (Viral Pathogens) considers the ways in which viruses cause disease. It examines the mechanisms by which viruses enter host cells, replicate within them and are finally released and transmitted from man to man and from animals to man. The host response to viral infection is described and the outcomes, including full recovery, acute infection, chronic infection, latent infection and death are considered. Specific examples, including measles virus, hepatitis B virus, herpes viruses and Ebola virus are described. The role of viruses in development of some cancers is discussed, examining the role of human papilloma virus in cervical cancer in particular. Finally retroviruses are discussed, including HIV and retroviruses used in gene therapy.

Teaching Methods

Teaching Activities
Category Activity Number Length Student Hours Comment
Scheduled Learning And Teaching ActivitiesLecture21:002:00Seminar - full module cohort in attendance
Scheduled Learning And Teaching ActivitiesLecture281:0028:00N/A
Scheduled Learning And Teaching ActivitiesSmall group teaching12:002:00Poster Presentation
Scheduled Learning And Teaching ActivitiesSmall group teaching12:002:00Scientific paper interpretation workshop
Guided Independent StudyIndependent study1166:00166:00N/A
Teaching Rationale And Relationship

Lectures will provide students with key information and guidance for additional reading.
Poster presentation and paper interpretation workshop develop interpersonal communication, increase understanding of lecture material and primary literature by discussion with peers and teachers and help prepare students for final exam. Private study will allow students to extend and reinforce their knowledge and understanding through reading of text books, journal articles and use of other recommended resources (eg online).

Assessment Methods

The format of resits will be determined by the Board of Examiners

Description Length Semester When Set Percentage Comment
Written Examination1202A80Unseen 50% EMI & 50% scientific paper interpretation exercise. Sister module at NuMed. Need timetabled at 9:30am - not on a Friday
Exam Pairings
Module Code Module Title Semester Comment
BMN2012Clinical Immunology and Viral Pathogens1Sister module delivered at NuMed. To be timetable at 9:30 am and not on a Friday.
Other Assessment
Description Semester When Set Percentage Comment
Prof skill assessmnt2M10Poster Presentation (10 mins) - team present a poster summarising experimental data from a scientific research paper
Prob solv exercises2M10Guided interpretation of a primary research paper (500-1000)
Assessment Rationale And Relationship

The EMI section of the examination will assess the students breadth of knowledge and understanding; the scientific paper interpretation section of the examination will assess the students ability to use their knowledge and understanding of the topics to data presented in a scientific research paper.

The poster presentation assesses information literacy, computer literacy, ability to interpret scientific papers, planning and organisation skills, group working skills and oral presentation skills. The scientific paper interpretation exercise assesses ability to interpret data presented in a scientific research paper and will prepare students for the scientific paper interpretation element of the examination.

Reading Lists