CMB2003 : Molecular Medicine

Semester 1 Credit Value: 20
ECTS Credits: 10.0


To provide basic information on:
•Recombinant DNA technology
•The applications of recombinant DNA technology to medicine
•Experimental methods of studying gene products (proteins)

To provide basic information on the transport processes that are found in cell and epithelial membranes.
To discuss the physiological role of these processes in cell function.
To discuss how malfunction of transport processes causes disease states.

Outline Of Syllabus

The Biomedical Sciences are underpinned by a knowledge base and a range of technologies in cell and molecular biology. This module will describe the way in which the molecular information that underpins many developments in the diagnosis and treatment of disease is produced and used. The strand “Approaches to Molecular Medicine” aims to prepare you for a future in the biosciences that will be increasingly built on knowledge gained from the availability of genome sequences. The transport of ions, molecules and water across cell membranes is a fundamental process that is essential for life. The strand “Cell and Membrane Transport” aims to develop your understanding of the molecular structure of cell membranes and of the diverse nature of their transport processes. You will also learn how disruption of membrane transport processes, such as occurs in cystic fibrosis and multi-drug resistance, may give rise to serious diseases in humans.

Content and teaching

The Molecular Medicine Module contains two strands

•       Approaches to Molecular Medicine
•       Cell and Membrane Transport

In addition to the lecture programme, the module will include a practical class, group CAL session and seminar work.

Teaching Methods

Teaching Activities
Category Activity Number Length Student Hours Comment
Guided Independent StudyAssessment preparation and completion1162:00162:00
Scheduled Learning And Teaching ActivitiesLecture311:0031:00
Scheduled Learning And Teaching ActivitiesPractical13:003:00
Scheduled Learning And Teaching ActivitiesSmall group teaching12:002:00
Scheduled Learning And Teaching ActivitiesSmall group teaching21:002:00One seminar for each strand.
Teaching Rationale And Relationship

Lectures will provide students with key information, highlight areas of importance and interrelate with directed reading and self directed learning.

The seminars and problem solving exercises will encourage increased understanding of the material delivered in lectures through discussion, and will develop skills of data interpretation, problem solving and information retrieval.

The practical will develop skills of data interpretation, problem solving and numeracy.
Private study will allow students to extend their knowledge through further reading and preparation for examinations.

Assessment Methods

The format of resits will be determined by the Board of Examiners

Description Length Semester When Set Percentage Comment
Written Examination1201A8030 minute Essay (25%), EMI: 20 five-part questions (75%)
Other Assessment
Description Semester When Set Percentage Comment
Practical/lab report1M5
Computer assessment1M10Online EMI
Prob solv exercises1M5
Assessment Rationale And Relationship

The end of the module examination tests knowledge and understanding (EMI and essay).
The in-course assessments are both formative and summative. The in-course EMI tests knowledge and understanding, and provides students with information about their progression of study. The problem solving exercise and practical tests the ability to apply knowledge and understanding to solve problems. The problem solving exercise also measures the skills of information retrieval and data interpretation.

Reading Lists