PED2005 : Systems Pharmacology (Inactive)

Semester 2 Credit Value: 20
ECTS Credits: 15.0


The module aims to provide you with:

• a knowledge and understanding of the physiological control of several major body systems
• a knowledge and understanding of the mechanisms by which drugs can modify the function of such systems
• an opportunity to further develop practical skills specific to pharmacological research
• an opportunity to research an area of drug treatment in further detail

Outline Of Syllabus

The module covers five major systems (themes) including the central nervous system, respiratory, gastrointestinal, endocrine system and inflammation/infection. Each theme describes the cellular and physiological control of that system in both health and disease states. The mechanism of action of drug classes used in the treatment of each disease state are then described as well as possible side effects and their causes. CNS and Endocrine themes are supported by a revision seminar and the gastrointestinal theme is supported by one computer aided learning (CAL) programme and three in vitro practicals.

Teaching Methods

Teaching Activities
Category Activity Number Length Student Hours Comment
Scheduled Learning And Teaching ActivitiesLecture221:0022:00N/A
Guided Independent StudyAssessment preparation and completion11:001:00CAL session - test
Guided Independent StudyAssessment preparation and completion11:001:00Essay
Scheduled Learning And Teaching ActivitiesPractical33:009:00Laboratory sessions
Scheduled Learning And Teaching ActivitiesPractical13:003:00CAL session
Scheduled Learning And Teaching ActivitiesSmall group teaching21:002:00CNS and Endocrine seminars
Guided Independent StudyIndependent study1162:00162:00Private study
Teaching Rationale And Relationship

Lectures are used to impart new information and to support students integrating their knowledge from other stages and modules of the course. The seminar sessions are designed to reinforce the taught material and provide an opportunity for students to clarify concepts or challenge their learning further through peer and staff discussions.

The CAL session introduces students to the specific in vivo techniques used in the practicals allowing students to have a trial an error approach which is not appropriate when using live tissue. The CAL also encourages students to consider the ethical issues associated with in vivo research. Practicals then provide a personal experience of essential practices, equipment and safety procedures in the laboratory. The practicals link directly with the GI theme of the module so provide contextual learning for the students.

Assessment Methods

The format of resits will be determined by the Board of Examiners

Description Length Semester When Set Percentage Comment
Written Examination1802A80N/A
Exam Pairings
Module Code Module Title Semester Comment
BMS2012Clinical Immunology and Viral Pathogens2N/A
MIC2025Bacterial interactions with human hosts and the immune system in human disease2N/A
Other Assessment
Description Semester When Set Percentage Comment
Practical/lab report2M15N/A
Assessment Rationale And Relationship

CAL test:
The short multiple choice style test assess student’s understanding of the practical equipment set up and the design of organ bath experiments prior to their laboratory sessions so ensures students have a good understanding of the techniques they will use. The test also assess students basic laboratory calculation skills which links directly with tasks set in the practical and more generally in all laboratory practice.
Practical reports:
These reports challenge the students to concisely summarise their experiment design and results in a manner they will have seen before in the literature but have never written themselves without a pro-forma. The reports assess the students’ theoretical knowledge of the GI system as well as their ability to use an evidence-based approach in their scientific writing. This is also useful training before the stage 3 dissertation projects.
The essay assess the students’ ability to review the scientific literature and integrate this with their taught material on the same general theme to produce a summary of the therapeutic area. This supports students in the development of their written communication skills and additional reading skills.

Reading Lists