|Semester 1 Credit Value:||15|
This module aims to introduce the molecular basis of cellular processes and the principles that underlie many biological events. Consideration is given to the implications in relation to health and disease.
The series of lectures describes the structure of proteins and their building blocks, the amino acids. Proteins are considered in relation to diseases such as BSE (mad cow disease), cancer, and Alzheimers disease. The role of proteins as enzymes is also discussed. The course then moves on to look at the molecules that contain the secrets of life itself: the nucleic acids, and at how the expression of genes is regulated.
An understanding of metabolism is crucial to make sense of health and disease, and students learn about the fate of the various nutrients within the body. We look at how glucose metabolism is controlled and what goes wrong in diabetes, and how cells produce the energy they need to carry out their various activities.
Lectures and seminars cover the following topics:
Proteins: Proteins and their building blocks; Proteins in health and disease; Enzymes; Protein purification.
Carbohydrates: The structure of sugars; Role of sugars in biology.
Nucleic acids: Phosphorus in biology; Relationship between DNA, RNA and proteins; Structure of DNA;
How structure of DNA explains its function in replication; DNA Sequencing and the human genome; Control of gene expression: RNA synthesis-Transcription; Protein synthesis-Translation.
Energy and cellular metabolism: glycolysis; TCA cycle; oxidative phosphorylation; gluconeogenesis; glycogen metabolism; fat metabolism; basic amino acid metabolism; alcohol metabolism.
At the end of the module students should be able to:
1. Describe the structures of proteins and nucleic acids and relate structure to function and discuss examples of disease states e.g. sickle cell anaemia, BSE and Alzheimer's.
2. Describe carbohydrate structure and function.
3. Explain how enzymes catalyse cellular processes and their role as targets for drugs and in diagnosis.
4. Explain the processes and control of gene expression.
5. Explain how glucose metabolism is controlled and what goes wrong in diabetes.
6. Explain how cells produce the energy required for cellular processes.
At the end of the module students should be able to:
1. Independently locate information about Biochemistry via the library, Blackboard and the internet, to support and reinforce material taught in lectures (information literacy)
2. Work with peers in small groups to solve Biochemistry related problems in seminars (problem solving & collaboration)
3. Effectively communicate knowledge of Biochemistry, obtained from lectures and private study, to peers and staff during seminars (oral and interpersonal communication skills)
|Graduate Skills Framework Applicable:||Yes|
|Guided Independent Study||Assessment preparation and completion||1||1:00||1:00||Formative class tests|
|Scheduled Learning And Teaching Activities||Lecture||31||1:00||31:00|
|Scheduled Learning And Teaching Activities||Small group teaching||4||1:00||4:00||Seminars|
|Guided Independent Study||Independent study||1||114:00||114:00|
1. Lectures will define the scope of the course and communicate basic knowledge as a basis for further study.
2. Seminars will encourage students to develop their understanding of the subject and interpersonal communication skills. They provide an opportunity for students to ask questions and exchange ideas in a small group setting. Skills practiced include critical thinking, numeracy, communication & team working.
3. Private study is used for self-directed learning and includes: reading lecture notes and texts; preparation for seminars; using learning resources on the Web. Skills practiced include critical thinking, active learning, numeracy, planning and organisation and independence.
The format of resits will be determined by the Board of Examiners
|Written Examination||90||1||A||100||EMI format 25-30 questions|
|Computer assessment||1||M||A mid-semester EMI (formative), 25-30 questions will be provided to students under exam conditions.|
The end of semester examination assesses knowledge and understanding of the course material. The formative EMI questions will help students assess their knowledge and understanding of course material as well as familiarise students with the format of an EMI exam.
FMS Schools offering Semester One modules available as ‘Study Abroad’ will, where required, provide an alternative assessment time for examinations that take place after the Christmas vacation. Coursework with submissions dates after the Christmas vacation will either be submitted at an earlier date or at the same time remotely.
The form of assessment will not vary from the original.
Disclaimer: The information contained within the Module Catalogue relates to the 2016/17 academic year. In accordance with University Terms and Conditions, the University makes all reasonable efforts to deliver the modules as described. Modules may be amended on an annual basis to take account of changing staff expertise, developments in the discipline, the requirements of external bodies and partners, and student feedback. Module information for the 2017/18 entry will be published here in early-April 2017. Queries about information in the Module Catalogue should in the first instance be addressed to your School Office.