Module Catalogue 2014/15

CMB2004 : Cell and Molecular Biology of the Immune System

  • Offered for Year: 2014/15
  • Module Leader(s): Dr Vanessa Armstrong
  • Owning School: Biomedical Sciences
Semesters
Semester 1 Credit Value: 10
ECTS Credits: 5.0
Pre Requisites
Code Title
CMB1003Microbiology and Immunology
Pre Requisite Comment

N/A

Co Requisites
Co Requisite Comment

N/A

Aims

- To develop knowledge and understanding of the molecular and cell biology underlying a specific immune response, and to describe how such responses can protect against infection.

Outline Of Syllabus

Antibodies, T cell receptors and MHC molecules
Genetics of antigen recognition systems
Lymphocyte development
Lymphocyte activation
Regulation of immune responses
Immunity against infection

Learning Outcomes

Intended Knowledge Outcomes

•       Describe the molecular structure of antibodies, T cell receptors and MHC class I and class II molecules

•       Explain the part played by each of these molecules in antigen-recognition by T and B lymphocytes

•       Describe the genetics of each of these types of molecule

•       Discuss how the diverse repertoire of antibodies and T cell receptors is generated

•       Explain how T cells are activated by antigens, and the consequences of this activation

•       Explain what is meant by T-dependent and T-independent antigens and describe how these activate B cells

•       Describe the stages in T and B cell maturation from pluripotent haematopoietic stem cells to virgin lymphocytes

•       Explain the need for immunological tolerance to self antigens and discuss how this is achieved

•       Discuss how immune responses can be regulated, and the significance of qualitative regulation of immune responses

•       Describe how specific immune responses can lead to the activation of effector mechanisms against infections with bacteria, viruses and eukaryotic parasites

Intended Skill Outcomes

- To be able to interpret scientific information, in this instance immunological data relating to case studies

Graduate Skills Framework

Graduate Skills Framework Applicable: Yes
  • Cognitive/Intellectual Skills
    • Critical Thinking : Present
    • Active Learning : Present
  • Interaction
    • Communication
      • Oral : Present
      • Interpersonal : Present
    • Team Working
      • Collaboration : Present

Teaching Methods

Teaching Activities
Category Activity Number Length Student Hours Comment
Scheduled Learning And Teaching ActivitiesLecture101:0010:00N/A
Scheduled Learning And Teaching ActivitiesSmall group teaching11:301:30Seminars
Guided Independent StudyIndependent study188:3088:30N/A
Total100:00
Teaching Rationale And Relationship

Lectures are used to impart information in a concise manner, to highlight areas of importance and to interrelate with directed reading and self-directed study. The seminar is used for developing higher level skills of data interpretation and problem-solving as well as information retrieval. Private study is used for self-directed learning including further reading and preparation for examinations.

Reading Lists

Assessment Methods

The format of resits will be determined by the Board of Examiners

Exams
Description Length Semester When Set Percentage Comment
Written Examination601A100EMI
Assessment Rationale And Relationship

Knowledge and understanding is assessed through a summative examination.

Timetable

Past Exam Papers

General Notes

N/A

Note: The Module Catalogue now reflects module information relating to academic year 14/15. Please contact your School Office if you require module information for a previous academic year.

Disclaimer: The University will use all reasonable endeavours to deliver modules in accordance with the descriptions set out in this catalogue. Every effort has been made to ensure the accuracy of the information, however, the University reserves the right to introduce changes to the information given including the addition, withdrawal or restructuring of modules if it considers such action to be necessary.