MMB8046 : Drug Delivery and Nanomedicine
MMB8046 : Drug Delivery and Nanomedicine
- Offered for Year: 2024/25
- Module Leader(s): Dr Wing Man Lau
- Lecturer: Dr Oisín Kavanagh, Dr Tatiane Machado, Professor Moein Moghimi, Dr Keng Wooi Ng
- Owning School: Biomedical, Nutritional and Sports Scien
- Teaching Location: Newcastle City Campus
Semesters
Your programme is made up of credits, the total differs on programme to programme.
| Semester 1 Credit Value: | 20 |
| ECTS Credits: | 10.0 |
| European Credit Transfer System | |
Pre-requisite
Modules you must have done previously to study this module
Pre Requisite Comment
Programme admission criteria only
Co-Requisite
Modules you need to take at the same time
Co Requisite Comment
N/A
Aims
The module aims to develop the student's knowledge and understanding of the scientific principles of medicine design, development and manufacture. Students will develop the ability to formulate potential novel therapeutic compounds into world-class medicine to address current market needs and propose a sound strategy to do so. It covers the technologies to design, develop and analyse micro and nano-scale materials, systems and devices. Industrial expertise will offer students an insight into pharmaceutical product development.
Outline Of Syllabus
The module covers the following areas, delivered through a series of lectures and interactive face-to-face seminars.
-Biological barriers for drug delivery
-Routes of drug administration
-Drug formulation design and development
-Targeted drug delivery systems and carriers
-Medicines manufacturing and quality control
-Latest advances in drug delivery and targeting
-Personalised medicine
-Pharmaceutical nanotechnology and nanomedicines
-Delivery of biopharmaceuticals
Learning Outcomes
Intended Knowledge Outcomes
By the end of this module the students should be able to:
• Discuss the scientific principles underpinning drug formulation.
• Outline the design and development of different drug delivery systems.
• Identify and discuss different routes of drug administration and the challenges encountered in those formulations.
• Display up-to-date knowledge of the major developments in formulation science and advanced drug delivery.
• Display an appropriate knowledge of the manufacture and quality control of pharmaceutical dosage forms.
• Display an appropriate understanding of the drug development process.
Intended Skill Outcomes
By the end of this module the students should be able to:
• Be proficient in the use of appropriate databases and critically assess primary and secondary literature.
• Critically evaluate the current developments in advanced formulation science and drug delivery.
• Apply advanced skills in interpretation and discussion of data and extrapolate the significance of the results to the pharmaceutical community at large.
• Critically appraise conventional drug delivery systems and review the rationale for advanced approaches to drug delivery.
Teaching Methods
Teaching Activities
| Category | Activity | Number | Length | Student Hours | Comment |
|---|---|---|---|---|---|
| Guided Independent Study | Assessment preparation and completion | 1 | 75:00 | 75:00 | Preparation and submission for in-course assessment |
| Scheduled Learning And Teaching Activities | Lecture | 11 | 1:00 | 11:00 | Present in person (PIP); Lectures |
| Guided Independent Study | Directed research and reading | 1 | 50:00 | 50:00 | Notes from lectures and reading |
| Scheduled Learning And Teaching Activities | Small group teaching | 1 | 3:00 | 3:00 | Present in person (PIP): Seminars |
| Scheduled Learning And Teaching Activities | Small group teaching | 2 | 2:00 | 4:00 | Present in person (PIP): Surgery |
| Scheduled Learning And Teaching Activities | Small group teaching | 5 | 2:00 | 10:00 | Present in person (PIP): Tutorials |
| Scheduled Learning And Teaching Activities | Small group teaching | 1 | 3:00 | 3:00 | Present in person (PIP): Presentation |
| Guided Independent Study | Student-led group activity | 4 | 3:00 | 12:00 | Student-led seminars and meetings |
| Guided Independent Study | Independent study | 1 | 31:00 | 31:00 | Independent Study |
| Scheduled Learning And Teaching Activities | Module talk | 1 | 1:00 | 1:00 | PIP - Introduction to the module |
| Total | 200:00 |
Teaching Rationale And Relationship
Theoretical content will be provided by lectures and provide a framework on which to construct further guided independent learning. Weekly interactive seminars will involve collaborative problem based activities that will encourage students to apply and build on the previous week’s learning and facilitate deeper learning on current research and development of advanced drug formulation and delivery through social interaction. Tutorial, seminars and student-lead activities also provide an opportunity to develop other skills including interpersonal skill, oral communication, collaboration, critical appraisal and information literacy. Surgery sessions provide extra opportunities for individual learning support that tailor to more specific individual learning needs.
Reading Lists
Assessment Methods
The format of resits will be determined by the Board of Examiners
Other Assessment
| Description | Semester | When Set | Percentage | Comment |
|---|---|---|---|---|
| Case study | 1 | M | 65 | Scientific literature review and prepare a formulation design proposal (max 2500 words) |
| Report | 1 | M | 35 | Complete an individual report describing case study formulation design (max 1000 words) |
Formative Assessments
Formative Assessment is an assessment which develops your skills in being assessed, allows for you to receive feedback, and prepares you for being assessed. However, it does not count to your final mark.
| Description | Semester | When Set | Comment |
|---|---|---|---|
| Oral Presentation | 1 | M | Present in person Oral presentation in small groups (15 minutes) |
Assessment Rationale And Relationship
The coursework will allow the students to show that they have fully understood all of the elements required in order to formulate an enhanced drug delivery system. Coursework is preferred as it provides a mechanism for the students to show that they are able to integrate the separate elements together to develop a specific drug formulation design.
Each student will be given a case based on a currently unmet pharmaceutical formulation need. Students will be expected to carry out a literature review to present the current knowledge and, based on that, to derive a proposal to meet the formulation need. Knowledge and skills will also be formatively assessed by small group presentation of a strategy relating to a new formulation development, followed by a question and answer session. This formative assessment will provide an opportunity for further feedback on their formulation design proposal. Each student will then submit a summative written plan to describe their chosen formulation design and how the chosen designed be tested. These tasks have been designed to prepare students for a typical working environment where team work and diplomacy are as important as knowledge.
Timetable
- Timetable Website: www.ncl.ac.uk/timetable/
- MMB8046's Timetable
Past Exam Papers
- Exam Papers Online : www.ncl.ac.uk/exam.papers/
- MMB8046's past Exam Papers
General Notes
N/A
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