Centre for In Vivo Imaging

Staff Profiles

Dr Christopher Morris

Senior Lecturer



I am a member of the Translational and Clinical Research Institute at the Medical Toxicology Centre, Wolfson Building where I am also a member of the NIHR HPRU in Chemical and Radiation Threats and Hazards.

At the Campus for Ageing and Vitality I am Scientific Director of the Newcastle Brain Tissue Resource and also a member of the Dementia and Neurodegenerative Diseases Group as part of the Mental Health, Dementia and Neurodegeneration theme.

Roles and Responsibilities

Designated Individual, Newcastle University Human Tissue Authority Research Licence

Chair, Translational and Clinical Research Institute GM Safety Committee

Advisory Committee on Pesticides, Member (2012-2015)

Expert Committee on Pesticides (2016-date)

Member of the Advisory Committee on Pesticides Medical and Toxicology Panel (2012-2015)

Chair, Peer Review Panel, Parkinson's UK and MS Society Brain Bank, Imperial College, London (2012-date)



Previous Positions

Medical Research Council Staff Scientist, MRC Neurochemical Pathology Unit, 1987-1999
Medical Research Council External Staff Scientist, MRC/University of Newcastle Centre Development in Clinical Brain Ageing, 2000-2005

Visiting Researcher, National Institutes of Genome Research/National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland USA, 2004

Health Protection Agency, Scientist, Chemical Hazards and Poisons Division, 2005-2006 


British Toxicology Society

Areas of expertiseNeuroscience, Neurtoxicology, Neurodegeneration, Alzheimer’s disease, Parkinson’s Disease, Dementia with Lewy Bodies

ORCID record at http://orcid.org/0000-0002-3749-0993

Google Scholar: Click here. 


My research focuses on the mechanisms that cause specific symptoms experienced by patients with different neurodegenerative disorders such as Alzheimer's disease, Dementia with Lewy Bodies and Parkinson's disease. We use brain tissue from well characterised donors and a variety of experimental approaches to investigate symptoms such as visual hallucinations, depression, anxiety, and memory problems. Our approach involves quantitative neuropathological investigation to determine if specific cell loss or pathology underpins symptoms and also molecular approaches including RNAseq, protein methods and genetic analysis to build an understanding of the different disorders to identify specific treatments.

My research also looks at how specific toxins might affect the nervous system and how they might contribute to late onset neurodegeneration. We are interested in how environmental chemicals, man made or natural, contribute to specific disorders such as Parkinson's disease. Understanding the mode of action of these chemicals may provide us with evidence of how the different neurodegenerative disorders occur.

We have a specific interest in the role of carbon monoxide as a contributor to long term motor and memory problems. Carbon monoxide is a major preventable cause of illness globally and can lead to chronic health problems following exposure even at low levels. We aim to identify new ways of detecting if people are exposed to carbon monoxide, and also to find ways to understand how carbon monoxide causes certain symptoms in exposed people.


"Molecular Mechanisms Underlying Visual Hallucinations in Dementia with Lewy Bodies" funding from the Alzheimer's Society June 2013-December 2015.

"Utility of Mitochondrial Complex IV Analysis as a Biomarker of Carbon Monoxide Exposure" funding from the Gas Safety Trust June 2016-March 2017

"Identification of protein biomarkers in peripheral blood lymphocytes following carbon monoxide exposure" funding from the Gas Safety Trust January 2018- November 2018. 

"NIHR Newcastle BioResource" funding from the National Institutes of Health Research, April 2018-March 2022.

"Developing Biochemical Methods to detect Dementia with Lewy bodies" funded by the Lewy Body Society, January 2019-May 2020.



Undergraduate Teaching

Biomedical Sciences BMS3013 Diseases of the Nervous System

Biomedical Science BMS3017 Clinical Ageing and Health

Postgraduate Teaching

MRCPsych Course

MRes in Medical and Molecular Biosciences  Research Skills and Principles for the Biosciences MMB8100

MRes in Medical and Molecular Biosciences, Genetic Basis of Common (Complex) Disease MMB8014

MRes in Medical and Molecular Biosciences, Toxicology  MMB8032