Background

Qualifications

M.B., B.Chir., M.A. (University of Cambridge)

Ph.D. (Imperial College London)

FRCP (Royal College of Physician, London)

CCT in Rheumatology (PMETB)

 Role and Responsibilities

- Professor of Rheumatology, Newcastle University

- Honorary Consultant Rheumatologist, Newcastle upon Tyne Hospitals NHS Foundation Trust

- Director, NIHR Newcastle Clinical Research Facility

- Deputy Lead, Musculoskeletal Theme, NIHR Newcastle Biomedical Research Centre

Memberships

- Royal College of Physicians, London

- British Society for Rheumatology

- British Society for Immunology

Honours and Awards

- Michael Mason Prize, British Society for Rheumatology (2015)

- Medical Research Council Clinician Scientist (2006-11, not taken up)

- Runner-up, Young Investigator Award, Medical Research Society

- Runner-up, Barbara Ansell Prize, Royal Society of Medicine

- Medawar Medal Finalist, British Society for Transplantation

- Wellcome Trust Training Fellowship

 

External Roles

- Coordinator, IDEA-FAST Consortium (www.idea-fast.eu)

- Chief investigator, UK primary Sjogren's syndrome registry (UKPSSR) (www.sjogrensregistry.org)

- Chief Investigator, Stratification in Sjogren's syndrome (SiSS) consortium 

- Expert panel, European League Against Rheumatism (EULAR) Sjogren's Syndrome Study Group

- Clinical Lead, NIHR BioResource for Rare Diseases for Sjogren's syndrome

- Trustee and Medical Council, British Sjogren's Syndrome Association 

- Steering Committee, Sjogren's syndrome clinical trial consortium, Sjogren's syndrome Foundation (US)

- Executive Project Management Team, NECESSITY consortium (www.necessity-h2020.eu)

- Steering Committee, EULAR Best Practice in the Management of Sjogren's Syndrome Group 

- Founding Co-convenor, European League Against Rheumatism (EULAR) Sjogren's Syndrome Study Group

- College of Experts, Arthritis Research UK 

- Steering Committee, HarmonicSS Consortium

Research

Research Interests

Stratified/Personalised Medicine in Sjogren's Syndrome

Fatigue 

Novel endpoint development including digital endpoints

Biomarker discovery (including digital biomarkers)

Bio-resource

Novel non-pharmacological therapeutics

Expertise

Sjogren's syndrome, Fatigue, Digital Medicine, Stratified Medicine

Current Work

1. I have established and continue to develop and maintain a world-leading bioresource for Sjogren's syndrome research - the UK primary Sjogren's syndrome registry, the UKPSSR (www.sjogrensregistry.org) - to promote and facilitate high quality research for the global research community in advancing the diagnosis and treatment of Sjogren's syndrome

2. I run a multi-disciplinary research programme with the aim to understand the pathophysiological mechanisms of fatigue and explore novel (including non-pharmacological) therapeutic strategies for this disabling symptom.

3. I lead a European consortium research programme to develop a stratified medicine approach to primary Sjogren's syndrome research and therapeutic development 

4. I am interested in novel endpoints development for disease assessment and therapeutic assessment (including the use of modern technologies such as wearables and other digital devices). Currently, I lead a €42 million European research programme to identify digital endpoints for fatigue, sleep disturbance and activities of daily living in neurodegenerative diseases and Immune-mediated inflammatory diseases. (www.idea-fast.eu)

Funding

EU Innovative Medicine Initiatives

Medical Research Council

FOREUM (European)

EU Horizon 2020

National Institute of Health Research

Arthritis Research UK / Versus Arthritis

British Sjogren's Syndrome Association

JGW Patterson Foundation Trust

Sir Jules Thorn Charitable Trust

Newcastle upon Tyne Hospitals NHS Foundation Trust

 

Teaching

Undergraduate Teaching

Musculoskeletal medicine - medical students

Sjogren's syndrome - Dental Students 

UG project students

Postgraduate Teaching

PG Cert/Dip/MRes in Clinical Research

- Co lead Module Designing a Research Proposal (MCR8013) 

Core Medical Trainees, NUTH 

Specialist trainees in Rheumatology

MRes/PhD/MD. supervisions

Publications

• Davies K, Ng W-F. Autonomic Nervous System Dysfunction in Primary Sjögren’s Syndrome. Frontiers in Immunology 2021, 12, 702505.
• Rayner F, Anderson AE, Baker KF, Buckley CD, Dyke B, Fenton S, Filer A, Goodyear CS, Hilkens CMU, Hiu S, Kerrigan S, Kurowska-Stolarska M, Matthews F, McInnes I, Ng W-F, Pratt AG, Prichard J, Raza K, Siebert S, Stocken D, Teare MD, Young S, Isaacs JD. BIOlogical Factors that Limit sustAined Remission in rhEumatoid arthritis (the BIO-FLARE study): protocol for a non-randomised longitudinal cohort study. BMC Rheumatology 2021, 5, 22.
• Davies K, Dures E, Ng W-F. Fatigue in inflammatory rheumatic diseases: current knowledge and areas for future research. Nature Reviews Rheumatology 2021, 17, 651-664.
• Posada J, Valadkhan S, Durge D, Davies K, Tarn J, Casement J, Jobling K, Gallagher P, Wilson D, Barone F, Fisher BA, Ng WF. Improvement of Severe Fatigue Following Nuclease Therapy in Patients With Primary Sjögren's Syndrome: A Randomized Clinical Trial. Arthritis and Rheumatology 2021, 73(1), 143-150.
• Posada J, Fisher BA, Ng W-F. Reply. Arthritis and Rheumatology 2021, 73(4), 718-719.
• Collins A, Lendrem D, Wason J, Tarn J, Howard-Tripp N, Bodewes I, Versnel MA, Gottenberg J-E, Seror R, Mariette X, Ng W-F. Revisiting the JOQUER trial: stratification of primary Sjögren’s syndrome and the clinical and interferon response to hydroxychloroquine. Rheumatology International 2021, 41, 1593-1600.
• Price E, Allen A, Rauz S, Tappuni A, Sutcliffe N, Bombardieri M, Carty S, Ciurtin C, Crampton B, Duncalfe L, Fisher B, Glennon P, Hackett KL, Larkin G, Ng W-F, Ramanan AV, Rassam S, Walsh SB, Bowman S. The management of Sjögren's syndrome: British Society for Rheumatology guideline scope. Rheumatology 2021, 60(5), 2122-2127.
• Cole M, Yap C, Buckley C, Ng WF, McInnes I, Filer A, Siebert S, Pratt A, Isaacs JD, Stocken DD. TRAFIC: statistical design and analysis plan for a pragmatic early phase 1/2 Bayesian adaptive dose escalation trial in rheumatoid arthritis. Trials 2021, 22(1), 433.
• Fisher BA, Szanto A, Ng WF, Bombardieri M, Posch MG, Papas AS, Farag AM, Daikeler T, Bannert B, Kyburz D, Kivitz AJ, Carsons SE, Isenberg DA, Barone F, Bowman SJ, Espie P, Floch D, Dupuy C, Ren X, Faerber PM, Wright AM, Hockey HU, Rotte M, Milojevic J, Avrameas A, Valentin MA, Rush JS, Gergely P. Assessment of the anti-CD40 antibody iscalimab in patients with primary Sjögren's syndrome: a multicentre, randomised, double-blind, placebo-controlled, proof-of-concept study. The Lancet Rheumatology 2020, 2(3), e142-e152.
• Ramos-Casals M, Brito-Zeron P, Bombardieri S, Bootsma H, De Vita S, Dorner T, Fisher BA, Gottenberg J-E, Hernandez-Molina G, Kocher A, Kostov B, Kruize AA, Mandl T, Ng W-F, Retamozo S, Seror R, Shoenfeld Y, Siso-Almirall A, Tzioufas AG, Vitali C, Bowman S, Mariette X. EULAR recommendations for the management of Sjögren's syndrome with topical and systemic therapies. Annals of the Rheumatic Diseases 2020, 79(1), 3-18.
• Davies K, Collins A, Charlton FG, Ng W-F. Nodular localized primary cutaneous amyloidosis and primary Sjögren’s syndrome. Scandinavian Journal of Rheumatology 2020, 49(2), 159-160.
• Traianos EY, Locke J, Lendrem D, Bowman S, Hargreaves B, Macrae V, Tarn JR, Ng W-F. Serum CXCL₁₃ levels are associated with lymphoma risk and lymphoma occurrence in primary Sjögren’s syndrome. Rheumatology International 2020, 40, 541-548.
• Acar-Denizli N, Horvath I-F, Mandl T, Priori R, Vissink A, Hernandez-Molina G, Armagan B, Praprotnik S, Sebastian A, Bartoloni E, Rischmueller M, Pasoto SG, Nordmark G, Nakamura H, Fernandes Moca Trevisani V, Retamozo S, Carsons SE, Maure-Noia B, Sanchez-Berna I, Lopez-Dupla M, Fonseca-Aizpuru E, Melchor Diaz S, Vazquez M, Diaz Cuiza PE, de Miguel Campo B, Ng W-F, Rasmussen A, Dong X, Li X, Baldini C, Seror R, Gottenberg J-E, Kruize AA, Sandhya P, Gandolfo S, Kwok S-K, Kvarnstrom M, Solans R, Sene D, Suzuki Y, Isenberg DA, Valim V, Hofauer B, Giacomelli R, Devauchelle-Pensec V, Atzeni F, Gheita TA, Morel J, Izzo R, Kalyoncu U, Szanto A, Olsson P, Bootsma H, Ramos-Casals M, Kostov B, Brito-Zeron P. Systemic phenotype related to primary Sjögren's syndrome in 279 patients carrying isolated anti-La/SSB antibodies. Clinical and Experimental Rheumatology 2020, 38(4), 85-94.
• Siebert S, Pratt AG, Stocken DD, Morton M, Cranston A, Cole M, Frame S, Buckley CD, Ng W-F, Filer A, McInnes IB, Isaacs JD. Targeting the rheumatoid arthritis synovial fibroblast via cyclin dependent kinase inhibition: An early phase trial. Medicine 2020, 99(26), e20458.
• Ng WF. Vagus nerve stimulation for autoimmune rheumatic diseases. The Lancet Rheumatology 2020, 2(9), e512-e513.
• Jousse-Joulin S, Gatineau F, Baldini C, Baer A, Barone F, Bootsma H, Bowman S, Brito-Zeron P, Cornec D, Dorner T, de Vita S, Fisher B, Hammenfors D, Jonsson M, Mariette X, Milic V, Nakamura H, Ng W-F, Nowak E, Ramos-Casals M, Rasmussen A, Seror R, Shiboski CH, Nakamura T, Vissink A, Saraux A, Devauchelle-Pensec V. Weight of salivary gland ultrasonography compared to other items of the 2016 ACR/EULAR classification criteria for Primary Sjögren’s syndrome. Journal of Internal Medicine 2020, 287(2), 180-188.
• Lewis I, Hackett KL, Ng W-F, Ellis J, Newton JL. A two-phase cohort study of the sleep phenotype within primary Sjögren's syndrome and its clinical correlates. Clinical and experimental rheumatology 2019, 37(3), 78-82.
• Lendrem BC, Lendrem DW, Pratt AG, Naamane N, McMeekin P, Ng W-F, Allen AJ, Power M, Isaacs JD. Between a ROC and a hard place: Teaching prevalence plots to understand real world biomarker performance in the clinic. Pharmaceutical Statistics 2019, 18(6), 632-635.
• Davies K, Mirza K, Tarn J, Howard-Tripp N, Bowman SJ, Lendrem D, UK Primary Sjögren’s Syndrome Registry, Ng W-F. Fatigue in primary Sjögren’s syndrome (pSS) is associated with lower levels of proinflammatory cytokines: a validation study. Rheumatology International 2019, 39, 1867-1873.
• Miyamoto SM, Lendrem DW, Ng WF, Hackett KL, Valim VL. Managing fatigue in patients with primary Sjögren’s syndrome: challenges and solutions. Open Access Rheumatology: Research and Reviews 2019, 11, 77-88.
• Miyamoto S, Lendrem DW, Ng W-F, Hackett K, Valim V. Managing fatigue in patients with primary Sjögren's syndrome. Open Access Rheumatology: Research and Reviews 2019, 11, 77-88.
• Venter M, Tomas C, Pienaar IS, Strassheim V, Erasmus E, Ng W-F, Howell N, Newton JL, Van der Westhuizen FH, Elson JL. MtDNA population variation in Myalgic encephalomyelitis/Chronic fatigue syndrome in two populations: a study of mildly deleterious variants. Scientific Reports 2019, 9(1), 2914.
• Clark JE, Ng W-F, Rushton S, Watson S, Newton JL. Network structure underpinning (dys) homeostasis in chronic fatigue syndrome; Preliminary findings. PLoS ONE 2019, 14(3), e0213724.
• Hackett KL, Davies K, Tarn J, Bragg R, Hargreaves B, Miyamoto S, McMeekin P, Mitchell S, Bowman S, Price EJ, Pease C, Emery P, Andrews J, Lanyon P, Hunter J, Gupta M, Bombardieri M, Sutcliffe N, Pitzalis C, McLaren J, Cooper A, Regan M, Giles I, Isenberg D, Vadivelu S, Coady D, Dasgupta B, McHugh N, Young-Min S, Moots R, Gendi N, Akil M, Griffiths B, Lendrem DW, Ng W-F. Pain and depression are associated with both physical and mental fatigue independently of comorbidities and medications in primary Sjögren's syndrome. RMD Open 2019, 5(1), e000885.
• Jobling K, Ledingham D, Ng WF, Guadagno J. Positive anti-MOG antibodies in a patient with Sjögren's syndrome and transverse myelitis. European Journal of Rheumatology 2019, 6(2), 102-104.
• Miyamoto ST, Valim V, Carletti L, Ng W-F, Perez AJ, Lendrem DW, Trennel M, Giovelli RA, Dias LH, Serrano EV, Subtil AM, Abreu VC, Natour J. Supervised walking improves cardiorespiratory fitness, exercise tolerance, and fatigue in women with primary Sjögren’s syndrome: a randomized-controlled trial. Rheumatology International 2019, 39(2), 227-238.
• Tarn J, Legg S, Mitchell S, Simon B, Ng WF. The Effects of Noninvasive Vagus Nerve Stimulation on Fatigue and Immune Responses in Patients With Primary Sjögren's Syndrome. Neuromodulation 2019, 22(5), 580-585.
• Jobling K, Rajabally H, Ng WF. Anti-Ro antibodies and complete heart block in adults with Sjögren’s syndrome. European Journal of Rheumatology 2018, 5(3), 194-196.
• James K, Chipeta C, Parker A, Harding S, Cockell SJ, Gillespie CS, Hallinan J, Barone F, Bowman SJ, Ng W-F, Fisher BA, for the UK Primary Sjögren's Syndrome Registry. B-cell activity markers are associated with different disease activity domains in primary Sjögren's syndrome. Rheumatology 2018, 57(7), 1222-1227.
• Jobling K, Ng WF. CD40 as a therapeutic target in Sjögren’s syndrome. Expert Review of Clinical Immunology 2018, 14(7), 535-537.
• Dumusc A, Ng W-F, James K, Griffiths B, Price E, Pease CT, Emery P, Lanyon P, Jones A, Bombardieri M, Sutcliffe N, Pitzalis C, Gupta M, McLaren J, Cooper A, Giles I, Isenberg D, Saravanan V, Coady D, Dasgupta B, McHugh N, Young-Min S, Moots RJ, Gendi N, Akil M, Barone F, Fisher BA, Rauz S, Richards A, Bowman SJ, Frankland H, Mediana A, Chadravarty K, Lamabadusuriya S, Adeniba R, Hamburger J, Higham J, Poveda-Galego A, Logan J, Mulherin D, Andrews J, McManus A, Booth A, Regan M, Dimitroulas T, Kadiki L, Kaur D, Kitas G, Lloyd M, Moore L, Gordon E, Lawson C, Hunter J, Stirton L, Ortiz G, Clunie G, Rose G, Cuckow S, Knight S, Symmons D, Jones B, Carr A, Edgar S, Carrozzo M, Figueiredo F, Foggo H, Gillespie C, Hindmarsh V, Lendrem D, Macleod I, Mitchell S, Tarn J, Muir A, White P, Pugmire S, Watkins M, Field A, Kaye S, Mewar D, Medcalf P, Tomlinson P, Whiteside D, Pauling J, James J, Olaitan N, McDermott J, Godia O, Kidd E, Palmer L, Katsande V, Long P, Chandra U, MacKay K, Fedele S, Ferenkeh-Koroma A, Marconnell H, Porter S, Brailsford S, Allcoat P. Comparison of ESSDAI and ClinESSDAI in potential optimisation of trial outcomes in primary Sjögren's syndrome: Examination of data from the UK Primary Sjögren's Syndrome Registry. Swiss Medical Weekly 2018, 148, w14588.
• Fisher BA, Everett CC, Rout J, O'Dwyer JL, Emery P, Pitzalis C, Ng WF, Carr A, Pease CT, Price EJ, Sutcliffe N, Makdissi J, Tappuni AR, Gendi NST, Hall FC, Ruddock SP, Fernandez C, Hulme CT, Davies KA, Edwards CJ, Lanyon PC, Moots RJ, Roussou E, Richards A, Sharples LD, Bombardieri M, Bowman SJ. Effect of rituximab on a salivary gland ultrasound score in primary Sjögren's syndrome: results of the TRACTISS randomised double-blind multicentre substudy. Annals of the Rheumatic Diseases 2018, 77(3), 412-416.
• Hackett KL, Deary V, Deane KHO, Newton JL, Ng W-F, Rapley T. Experience of sleep disruption in primary Sjögren’s syndrome: A focus group study. British Journal of Occupational Therapy 2018, 81(4), 218-226.
• Brito-Zeron P, Acar-Denizli N, Ng WF, Zeher M, Rasmussen A, Mandl T, Seror R, Li X, Baldini C, Gottenberg J-E, Danda D, Quartuccio L, Priori R, Hernandez-Molina G, Armagan B, Kruize AA, Kwok S-K, Kvarnstrom M, Praprotnik S, Sene D, Bartoloni E, Solans R, Rischmueller M, Suzuki Y, Isenberg DA, Valim V, Wiland P, Nordmark G, Fraile G, Bootsma H, Nakamura T, Giacomelli R, Devauchelle-Pensec V, Knopf A, Bombardieri M, Trevisani V-F, Hammenfors D, Pasoto SG, Retamozo S, Gheita TA, Atzeni F, Morel J, Vollenveider C, Horvath I-F, Sivils KL, Olsson P, De Vita S, Sanchez-Guerrero J, Kilic L, Wahren-Herlenius M, Mariette X, Ramos-Casals M, Brito-Zeron P, Morcillo C, Brito-Zeron P, Flores-Chavez A, Ramos-Casals M, Acar-Denizli N, Ng WF, Zeher M, Horvath I-F, Rasmussen A, Sivils K, Scofield H, Seror R, Mariette X, Mandl T, Olsson P, Li X, Baldini C, Gottenberg JE, Danda D, Sandhya P, Quartuccio L, Corazza L, De Vita S, Priori R, Hernandez-Molina G, Sanchez-Guerrero J, Kruize AA, Van Der Heijden E, Valim V, Kvarnstrom M, Wahren-Herlenius M, Sene D, Gerli R, Bartoloni E, Praprotnik S, Isenberg DA, Solans R, Rischmueller M, Downie-Doyle S, Kwok S-K, Park S-H, Nordmark G, Suzuki Y, Kawano M, Giacomelli R, Carubbi F, Devauchelle-Pensec V, Saraux A, Bombardieri M, Astorri E, Hofauer B, Knopf A, Bootsma H, Vissink A, Brun JG, Hammenfors D, Fraile G, Carsons SE, Gheita TA, Khalil HM, Morel J, Vollenveider C, Atzeni F, Retamozo S, Moca Trevisano V, Armagan B, Kilic L, Nakamura T, Sebastian A, Wiland P, Pasoto S, Kostov B, Siso-Almirall A, Sibilia J, Miceli-Richard C, Nocturne G, Benessiano J, Dieude P, Dubost J-J, Fauchais A-L, Goeb V, Hachulla E, Hatron PY, Larroche C, Le Guern V, Puechal X, Morel J, Perdriger A, Rist S, Vittecoq O, Ravaud P, Diaz-Lopez B, Feijoo C, Pallares L, Lopez-Dupla M, Perez-Alvarez R, Ripoll M, Pinilla B, Akasbi M, Maure B, Fonseca E, Canora J, De La Red G, Chamorro AJ, Jimenez-Heredia I, Fanlo P, Guisado-Vasco P, Zamora M. How immunological profile drives clinical phenotype of primary Sjögren's syndrome at diagnosis: Analysis of 10,500 patients (Sjögren Big Data Project). Clinical and Experimental Rheumatology 2018, 36, S102-S111.
• Hackett KL, Deane KHO, Newton JL, Deary V, Bowman SJ, Rapley T, Ng W-F. Mixed-Methods Study Identifying Key Intervention Targets to Improve Participation in Daily Living Activities in Primary Sjögren's Syndrome Patients. Arthritis Care and Research 2018, 70(7), 1064-1073.
• Lynn M, Maclachlan L, Finkelmeyer A, Clark J, Locke J, Todryk S, Ng W-F, Newton JL, Watson S. Reduction of Glucocorticoid Receptor Function in Chronic Fatigue Syndrome. Mediators of Inflammation 2018, 2018, 3972104.
• Bodewes ILA, Al-Ali S, vanHelden-Seeuwsen CG, Maria NI, Tarn JR, Lendrem DW, Schreurs MWJ, Steenwijk EC, vanDaele PLA, Both T, Bowman SJ, Griffiths B, Ng WF, Versnel MA. Systemic interferon type I and type II signatures in primary Sjögren’s syndrome reveal differences in biological disease activity. Rheumatology 2018, 57(5), 921-930.
• Carapito R, Gottenberg J-E, Kotova I, Untrau M, Michel S, Naegely L, Aouadi I, Kwemou M, Paul N, Pichot A, Locke J, Bowman SJ, Griffiths B, Sivils KL, Sibilia J, Inoko H, Micelli-Richard C, Nocturne G, Ota M, Ng W-F, Mariette X, Bahram S. A new MHC-linked susceptibility locus for primary Sjögren's syndrome: MICA. Human Molecular Genetics 2017, 26(13), 2565-2576.
• Hackett KL, Gotts ZM, Ellis J, Deary V, Rapley T, Ng W-F, Newton JL, Deane KHO. An investigation into the prevalence of sleep disturbances in primary Sjögren’s syndrome: a systematic review of the literature. Rheumatology 2017, 56(4), 570-580.
• Schoeman EM, Van Der Westhuizen FH, Erasmus E, van Dyk E, Knowles CVY, Al-Ali S, Ng W-F, Taylor RW, Newton JL, Elson JL. Clinically proven mtDNA mutations are not common in those with chronic fatigue syndrome. BMC Medical Genetics 2017, 18, 29.
• Ramos-Casals M, Brito-Zeron P, Seror R, Bootsma H, Bowman SJ, Dorner T, Gottenberg J-E, Mariette X, Theander E, Bombardieri S, De Vita S, Mandl T, Ng W-F, Kruize A, Tzioufas A, Vitali C. Corrigendum: Characterization of systemic disease in primary Sjögren's syndrome: EULAR-SS Task Force recommendations for articular, cutaneous, pulmonary and renal involvements [Rheumatology, 54, (2015) (2230-2238)] DOI: 10.1093/rheumatology/kev200. Rheumatology 2017, 56(7), 1245-1245.
• Oni C, Mitchell S, James K, Ng W-F, Griffiths B, Hindmarsh V, Price E, Pease CT, Emery P, Lanyon P, Jones A, Bombardieri M, Sutcliffe N, Pitzalis C, Hunter J, Gupta M, McLaren J, Cooper A, Regan M, Giles I, Isenberg D, Saravanan V, Coady D, Dasgupta B, McHugh N, Young-Min S, Moots R, Gendi N, Akil M, Barone F, Fisher B, Rauz S, Richards A, Bowman SJ. Corrigendum: Eligibility for clinical trials in primary Sjögren's syndrome: Lessons from the UK Primary Sjögren's Syndrome Registry [Rheumatology, 55, (2016) (544-552)] doi:10.1093/rheumatology/kev373. Rheumatology 2017, 56(12), 2255-2255.
• Li H, Reksten TR, Ice JA, Kelly JA, Adrianto I, Rasmussen A, Wang S, He B, Grundahl KM, Glenn SB, Miceli-Richard C, Bowman S, Lester S, Eriksson P, Eloranta M-L, Brun JG, Goransson LG, Harboe E, Guthridge JM, Kaufman KM, Kvarnstrom M, Cunninghame Graham DS, Patel K, Adler AJ, Farris AD, Brennan MT, Chodosh J, Gopalakrishnan R, Weisman MH, Venuturupalli S, Wallace DJ, Hefner KS, Houston GD, Huang AJW, Hughes PJ, Lewis DM, Radfar L, Vista ES, Edgar CE, Rohrer MD, Stone DU, Vyse TJ, Harley JB, Gaffney PM, James JA, Turner S, Alevizos I, Anaya J-M, Rhodus NL, Segal BM, Montgomery CG, Scofield RH, Kovats S, Mariette X, Ronnblom L, Witte T, Rischmueller M, Wahren-Herlenius M, Omdal R, Jonsson R, Ng W-F, Nordmark G, Lessard CJ, Sivils KL. Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons. PLoS Genetics 2017, 13(6), e1006820.
• Ng WF, Miller A, Bowman SJ, Price EJ, Kitas GD, Pease C, Emery P, Lanyon P, Hunter J, Gupta M, Giles I, Isenberg D, McLaren J, Regan M, Cooper A, Young-Min SA, McHugh N, Vadivelu S, Moots RJ, Coady D, MacKay K, Dasgupta B, Sutcliffe N, Bombardieri M, Pitzalis C, Griffiths B, Mitchell S, Tatiyama Miyamoto S, Trenell M, on behalf of the UK Primary Sjögren’s Syndrome Registry. Physical activity but not sedentary activity is reduced in primary Sjögren’s syndrome. Rheumatology International 2017, 37(4), 623-631.
• Battersby AC, Martin AJ, Tarn J, Ng WF, Cale CM, Goldblatt D, Gennery AR. Raised Serum IL-8 Levels Are Associated with Excessive Fatigue in Female Carriers of X-Linked Chronic Granulomatous Disease in the UK. Journal of Clinical Immunology 2017, 37(3), 279-281.
• Bowman SJ, Everett CC, O'Dwyer JL, Emery P, Pitzalis C, Ng W-F, Pease CT, Price EJ, Sutcliffe N, Gendi NST, Hall FC, Ruddock SP, Fernandez C, Reynolds C, Hulme CT, Davies KA, Edwards CJ, Lanyon PC, Moots RJ, Roussou E, Giles IP, Sharples LD, Bombardieri M. Randomized Controlled Trial of Rituximab and Cost-Effectiveness Analysis in Treating Fatigue and Oral Dryness in Primary Sjögren's Syndrome. Arthritis and Rheumatology 2017, 69(7), 1440-1450.
• Sharma R, Harris VM, Cavett J, Kurien BT, Liu K, Koelsch KA, Fayaaz A, Chaudhari KS, Radfar L, Lewis D, Stone DU, Kaufman CE, Li S, Segal B, Wallace DJ, Weisman MH, Venuturupalli S, Kelly JA, Pons-Estel B, Jonsson R, Lu X, Gottenberg J-E, Anaya J-M, Cunninghame-Graham DS, Huang AJW, Brennan MT, Hughes P, Alevizos I, Miceli-Richard C, Keystone EC, Bykerk VP, Hirschfield G, Nordmark G, Bucher SM, Eriksson P, Omdal R, Rhodus NL, Rischmueller M, Rohrer M, Wahren-Herlenius M, Witte T, Alarcon-Riquelme M, Mariette X, Lessard CJ, Harley JB, Ng W-F, Rasmussen A, Sivils KL, Scofield RH. Rare X Chromosome Abnormalities in Systemic Lupus Erythematosus and Sjögren's Syndrome. Arthritis and Rheumatology 2017, 69(11), 2187–2192.
• Jousse-Joulin S, Nowak E, Cornec D, Brown J, Carr A, Carotti M, Fisher B, Fradin J, Hocevar A, Jonsson MV, Luciano N, Milic V, Rout J, Theander E, Stel A, Bootsma H, Vissink A, Baldini C, Baer A, Ng WF, Bowman S, Alavi Z, Saraux A, Devauchelle-Pensec V. Salivary gland ultrasound abnormalities in primary Sjögren's syndrome: Consensual US-SG core items definition and reliability. RMD Open 2017, 3(1), e000364.
• Fisher BA, Jonsson R, Daniels T, Bombardieri M, Brown RM, Morgan P, Bombardieri S, Ng W-F, Tzioufas AG, Vitali C, Shirlaw P, Haacke E, Costa S, Bootsma H, Devauchelle-Pensec V, Radstake TR, Mariette X, Richards A, Stack R, Bowman SJ, Barone F. Standardisation of labial salivary gland histopathology in clinical trials in primary Sjögren's syndrome. Annals of the Rheumatic Diseases 2017, 76(7), 1161-1168.
• Bezzina OM, Gallagher P, Mitchell S, Bowman SJ, Griffiths B, Hindmarsh V, Hargreaves B, Price EJ, Pease CT, Emery P, Lanyon P, Bombardieri M, Sutcliffe N, Pitzalis C, Hunter J, Gupta M, McLaren J, Cooper AM, Regan M, Giles IP, Isenberg DA, Vadivelu S, Coady D, Dasgupta B, McHugh NJ, Young-Min SA, Moots RJ, Gendi N, Akil M, MacKay K, Ng WF, Robinson LJ. Subjective and Objective Measures of Dryness Symptoms in Primary Sjögren’s Syndrome – Capturing the discrepancy. Arthritis Care & Research 2017, 69(11), 1714-1723.
• Price EJ, Rauz S, Tappuni AR, Sutcliffe N, Hackett KL, Barone F, Granata G, Ng W-F, Fisher BA, Bombardieri M, Astorri E, Empson B, Larkin G, Crampton B, Bowman SJ. The British Society for Rheumatology guideline for the management of adults with primary Sjögren's Syndrome. Rheumatology 2017, 56(10), 1643-1647.
• Hart RI, Ng WF, Newton JL, Hackett KL, Lee RP, Thompson B. What impact does written information about fatigue have on patients with autoimmune rheumatic diseases? Findings from a qualitative study. Musculoskeletal Care 2017, 15(3), 230-237.
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• Collins K, Balasubramaniam K, Viswanathan G, Natasari A, Tarn J, Lendrem D, Mitchell S, Zaman A, Ng W-F. Assessment of blood clot formation and platelet receptor function ex vivo in patients with primary Sjögren’s syndrome. BMJ Open 2013, 3(5), e002739.
• Nordmark G, Wang C, Vasaitis L, Eriksson P, Theander E, Kvarnström M, Forsblad-d'Elia H, Jazebi H, Sjöwall C, Reksten TR, Brun JG, Jonsson MV, Johnsen SJ, Wahren-Herlenius M, Omdal R, Jonsson R, Bowman S, Ng WF, Eloranta ML, Syvänen AC, UK Primary Sjögren's Syndrome Registry, Carr A, Corbett I, Carrozzo M, Lendrem D, Macleod I, Mawson P, Stocks P. Association of genes in the NF-κB pathway with antibody-positive primary Sjögren's syndrome. Scandinavian Journal of Immunology 2013, 78(5), 447-454.
• Coulson E, Ng WF, Platt PN, Foster HE. Cardiovascular Risk In Adults With Juvenile Idiopathic Arthritis. In: Arthritis & Rheumatism 2013 Annual Meeting. 2013, San Diego, CA, USA: John Wiley & Sons, Inc.
• Coulson EJ, Ng W-F, Goff I, Foster HE. Cardiovascular risk in juvenile idiopathic arthritis. Rheumatology 2013, 52(7), 1163-1171.
• Elshahaly M, Wheater G, Naraghi K, Tuck SP, Datta HK, Ng WF, van Laar JM. Changes in bone density and bone turnover in patients with rheumatoid arthritis treated with rituximab, a B cell depleting monoclonal antibody (HORUS TRIAL). In: Abstracts from the Combined Northern and Yorkshire Deaneries Rheumatology Annual Conference 2012. 2013, York, UK: BioMed Central Ltd.
• Lessard CJ, Li H, Adrianto I, Ice JA, Dozmorov MG, Jonsson R, Rischmueller M, Nordmark G, Mariette X, Miceli-Richard C, Wahren-Herlenius M, Witte T, Brennan MT, Omdal R, Ronnblom L, Gaffney PM, Ng WF, Rhodus NL, Segal BM, Wren JD, Scofield RH, Anaya JM, Harley JB, Montgomery CG, Sivils KL. Complex Functional Effects Within The HLA Contribute To Sjogren's Syndrome Pathogenesis and May Influence Both Transcriptional Regulation and Peptide Binding. In: 77th Annual Meeting of the American College of Rheumatology/48th Annual Meeting of the Association of Rheumatology Health Professionals. 2013, San Diego, CA, USA: Wiley-Blackwell.
• Natasari AS, Tarn JR, Fischer R, Lendrem DW, Ng W-F. Exploring the biological basis of fatigue using primary Sjögren's syndrome as a disease model. BMC Musculoskeletal Disorders 2013, 14(S1), A1.
• Lessard CJ, Li H, Ice JA, Adrianto I, Jonsson R, Illei GG, Rischmueller M, Nordmark G, Mariette X, Miceli-Richard C, Herlenius MW, Witte T, Brennan M, Omdal R, Gaffney PM, Lessard JA, Ronnblom L, Ng WF, Rhodus N, Segal B, Scofield RH, James JA, Anaya JM, Montgomery CG, Harley JB, Sivils KM. Identification of Multiple Sjögren’s Syndrome Susceptibility Loci. In: Annual European Congress of Rheumatology EULAR. 2013, Madrid, Spain: BMJ Publishing Group.
• Ng WF, Miller A, Bowman S, Price E, Kitas G, Pease C, Emery P, Lanyon P, Hunter J, Gupta M, Giles I, Isenberg D, MaClaren J, Regan M, Cooper A, Young-Min S, Bombardieri M, Sutcliffe N, Pitzalis C, Vadivelu S, Coady D, MacKay K, Moots R, Mitchell S, Mchugh N, Dasgupta B, Trenell M, UKPS SR. Level of Physical Activity in Primary Sjögren's Syndrome and its Predictors. In: Annual European Congress of Rheumatology EULAR. 2013, Madrid, Spain: BMJ Publishing Group.
• Liu K, Kaufman KM, James JA, Jonsson R, Kurien BT, Mariette X, Merrill JT, Omdal R, Rischmueller M, Vyse TJ, Wahren-Herlenius M, Witte T, Lessard CJ, Zimmerman SL, Thompson SD, Hirschfield G, Xie G, Montgomery CG, Ng WF, Nordmark G, Gaffney PM, Siminovitch KA, Sivils KL, Scofield RH, Slegen Int Consortium Genetics SLE. Sex Bias In Autoimmune Diseases: Increased Risk Of 47,XXX In Systemic Lupus Erythematosus (SLE) and Sjogren's Syndrome (SS) Supports The Gene Dose Hypothesis. In: ACR/ARHP Annual Meeting 2013. 2013, San Diego, CA, USA: John Wiley & Sons Ltd.
• Cooles FAH, Pratt AG, Ng WF, Aspray TJ, Isaacs JD. The Effect Of Vitamin D On Early Rheumatoid Arthritis: A Retrospective Cohort Analysis. In: ACR/ARHP Annual Meeting 2013. 2013, San Diego, CA, USA: Wiley-Blackwell.
• Lessard CJ, Li H, Adrianto I, Ice JA, Rasmussen A, Grundahl KM, Kelly JA, Dozmorov MG, Miceli-Richard C, Bowman S, Lester S, Eriksson P, Eloranta ML, Brun JG, Gøransson LG, Harboe E, Guthridge JM, Kaufman KM, Kvarnström M, Jazebi H, Cunninghame Graham DS, Grandits ME, Nazmul-Hossain AN, Patel K, Adler AJ, Maier-Moore JS, Farris AD, Brennan MT, Lessard JA, Chodosh J, Gopalakrishnan R, Hefner KS, Houston GD, Huang AJ, Hughes PJ, Lewis DM, Radfar L, Rohrer MD, Stone DU, Wren JD, Vyse TJ, Gaffney PM, James JA, Omdal R, Wahren-Herlenius M, Illei GG, Witte T, Jonsson R, Rischmueller M, Rönnblom L, Nordmark G, Ng WF, Mariette X, Anaya JM, Rhodus NL, Segal BM, Scofield RH, Montgomery CG, Harley JB, Sivils KL. Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome. Nature Genetics 2013, 45(11), 1284-1292.
• Lessard CJ, Li H, Adrianto I, Ice JA, Jonsson R, Illei GG, Rischmueller M, Nordmark G, Mariette X, Miceli-Richard C, Wahren-Herlenius M, Witte T, Brennan MT, Omdal R, Gaffney PM, Lessard JA, Ng WF, Rhodus NL, Segal BM, Scofield RH, James JA, Anaya JM, Harley JB, Montgomery CG, Sivils KM. A Genome-Wide Association Study Establishes Muliple Susceptibility Loci for Sjogren's Syndrome. In: Annual Scientific Meeting of the American College of Rheumatology (ACR). 2012, Washington, DC, USA: John Wiley & Sons, Inc.
• Newton JL, Frith J, Powell D, Hackett K, Wilton K, Bowman S, Price E, Pease C, Andrews J, Emery P, Hunter J, Gupta M, Vadivelu S, Giles I, Isenberg D, Lanyon P, Jones A, Regan M, Cooper A, Moots R, Sutcliffe N, Bombardieri M, Pitzalis C, McLaren J, Young-Min S, Dasgupta B, Griffiths B, Lendrem D, Mitchell S, Ng WF. Autonomic symptoms are common and are associated with overall symptom burden and disease activity in primary Sjögren's syndrome. Annals of the Rheumatic Diseases 2012, 71(12), 1973-1979.
• Lendrem D, Mitchell S, Bowman S, Price E, Pease CT, Emery P, Andrews J, Bombardieri M, Sutcliffe N, Pitzalis C, Lanyon P, Hunter J, Gupta M, McLaren J, Regan M, Cooper A, Giles I, Isenberg D, Griffiths B, Foggo H, Edgar S, Vadivelu S, Coady D, McHugh N, Ng WF. Evaluating health status of 620 patients with primary sjögren’s syndrome using EQ-5D. In: Annual Meeting of the British Society for Rheumatology. 2012, Glasgow, UK: Oxford University Press.
• Ng WF, Lendrem D, Mitchell S, Bowman S, Price E, Pease C, Emery P, Andrews J, Bombardieri M, Sutcliffe N, Pitzalis C, Lanyon P, Hunter J, Gupta M, McLaren J, Regan M, Cooper A, Giles I, Isenberg D, Vadivelu S, Coady D, Griffiths B, United Kingdom Primary Sjogrens Syndrome. Evaluating health status of 620 patients with primary Sjögren's syndrome using EQ-5D. In: Annual European Congress of Rheumatology EULAR. 2012, Berlin, Germany: BMJ Publishing Group.
• Ng WF, Mitchell S, Lendrem D, Bowman S, Price E, Pease C, Emery P, Andrews J, Bombardieri M, Sutcliffe N, Pitzalis C, Lanyon P, Hunter J, Gupta M, McLaren J, Regan M, Cooper A, Giles I, Isenberg D, Vadivelu S, Coady D, Griffiths B, United Kingdom Primary Sjogren's. How good are the EULAR Sj ögren's syndrome disease activity index (ESSDAI), and EULAR Sj ögren's syndrome patients reported index (ESSPRI) in predicting health status in primary Sj ögren's syndrome? Normal 0 false false false EN-GB X-NONE X-NONE Normal 0 false false false EN-GB X-NONE X-NONE Normal 0 false false false EN-GB X-NONE X-NONE. In: Annual European Congress of Rheumatology EULAR. 2012, Berlin, Germany: BMJ Publishing Group.
• Lendrem D, Mitchell S, Bowman S, Price E, Pease CT, Emery P, Andrews J, Bombardieri M, Sutcliffe N, Pitzalis C, Lanyon P, Hunter J, Gupta M, McLaren J, Regan M, Cooper A, Giles I, Isenberg D, Vadivelu S, Coady D, McHugh N, Griffiths B, Foggo H, Edgar S, Ng WF. How good are the eular sjögren’s syndrome disease activity index, and eular sjögren’s syndrome patients reported index in predicting health status in primary sjögren’s syndrome?. In: Annual Meeting of the British Society for Rheumatology. 2012, Glasgow, UK: Oxford University Press.
• Hackett K, Newton J, Ng WF. Occupational therapy: a potentially valuable intervention for people with primary Sjogren's syndrome. British Journal of Occupational Therapy 2012, 75(5), 247-249.
• Collins K, Mitchell S, Griffiths B, Bowman SJ, Ng WF, on behalf of the United Kingdom Primary Sjogren's Syndrome Registry. Potential diagnostic utility of anti-centromere antibody in primary Sjogren's syndrome in the UK. Clinical Rheumatology 2012, 31(7), 1147-1148.
• Ng WF, Stangroom AJ, Davidson A, Wilton K, Mitchell S, Newton JL. Primary Sjogrens syndrome is associated with impaired autonomic response to orthostasis and sympathetic failure. QJM 2012, 105(12), 1191-1199.
• Ng WF. Primary Sjogren's Syndrome Research and Therapy: Has a New Dawn Arrived?. Current Pharmaceutical Biotechnology 2012, 13(10), 1987-1988.
• Tarn J, Mitchell S, Bowman S, Price E, Pease C, Sutcliffe N, Emery P, Andrews J, Bombardieri M, Pitzalis C, Lanyon P, Hunter J, Gupta M, Regan M, Cooper A, Giles I, Isenberg D, Young D, Lendrem D, McLaren J, Downie C, Foggo H, Stocks P, Edgar S, Ng WF, UK Primary Sjogrens Syndrome. Serum cytokine and chemokine profiling in primary Sj ögren's syndrome Normal 0 false false false EN-GB X-NONE X-NONE. In: Annual European Congress of Rheumatology EULAR. 2012, Berlin, Germany: BMJ Publishing Group.
• Carr AJ, Ng WF, Figueiredo F, Macleod RI, Greenwood M, Staines K. Sjogren's syndrome - an update for dental practitioners. British Dental Journal 2012, 213(7), 353-357.
• Tarn J, Natasari A, Mitchell S, Lendrem D, Downie C, Foggo H, Young D, Ng W, Bowman S. Soluble molecule profiling and network analysis of primary Sjogren's syndrome patient serum. In: European Congress of Immunology. 2012, Glasgow, UK: Wiley-Blackwell Publishing Ltd.
• Vila J, Mitchell S, Bowman S, Price E, Pease CT, Emery P, Andrews J, Bombardieri M, Sutcliffe N, Pitzalis C, Lanyon P, Hunter J, Gupta M, McLaren J, Regan M, Cooper A, Giles I, Isenberg D, Vadivelu S, Coady D, Griffiths B, Lendrem D, Foggo H, Tarn J, Ng WF. The clinical relevance of anti-RO52 and anti-RO60 in patients in the united kingdom primary sjögren’s syndrome registry (UKPSSR). In: Annual Meeting of the British Society for Rheumatology. 2012, Glasgow, UK: Oxford University Press.
• Carr A, Macleod I, Ng WF. The diagnostic utility of salivary gland ultrasound for the investigation of sjögren's syndrome. In: Annual Meeting of the British Society for Rheumatology. 2012, Glasgow, UK: Oxford University Press.
• Lessard CJ, Ice JA, Adrianto I, Kelly JA, Jonsson R, Illei GG, Rischmueller M, Nordmark G, Mariette X, Miceli-Richard C, Herlenius MW, Witte T, Brennan MT, Omdal R, Vyse TJ, Lessard JA, Ng WF, Rhodus NL, Segal BM, Scofield RH, Anaya JM, Harley JB, Montgomery CG, Moser KL, Benjamin A Rybicki ACCESS. A High-Density Genome-Wide Association Study by the Sjogren's Genetics Network Identifies Five Novel Susceptibility Loci for Primary Sjogren's Syndrome and Confirms Association with MHC, IRF5, and BLK. In: Arthritis & Rheumatism: 75th Annual Scientific Meeting of the American College of Rheumatology. 2011, Chicago, Illinois, USA: John Wiley & Sons, Inc.
• Ng WF, Bowman SJ. Biological therapies in primary Sjogren's syndrome. Expert Opinion on Biological Therapy 2011, 11(7), 921-936.
• Ng WF, Tudhope SJ, von Delwig A, Lilic D. Invariant natural killer T (iNKT) cell deficiency in chronic mucocutaneous candidiasis - A consequence or a cause?. Immunology Letters 2011, 135(1-2), 180-183.
• Lessard CJ, Adrianto I, Ice JA, Kelly JA, Jonsson R, Illei GG, Rischmueller M, Nordmark G, Mariette X, Miceli-Richard C, Herlenius MW, Witte T, Brennan MT, Omdal R, Gaffney PM, Lessard JA, Ng WF, Rhodus NL, Segal BM, Scofield RH, James JA, Anaya JM, Harley JB, Montgomery C, Moser KL. Large-Scale, High-Density Genotyping Performed by the Sjogren's Genetics Network Using the ImmunoChip Identifies PRKRA as a Novel Sjogren's Syndrome Susceptibility Locus and Confirms Associations with IRF5, BLK and MHC. In: Arthritis & Rheumatism: 75th Annual Scientific Meeting of the American College of Rheumatology. 2011, Chicago, Illinois, USA: John Wiley & Sons, Inc.
• Newton J, Powell D, Mitchell S, Griffiths B, Bowman S, Ng WF, UK Primary Sjogren's Syndrome. Potentially treatable symptoms in primary Sjogren's Syndrome - Associated fatigue. In: Rheumatology: Annual Meeting of the British Society for Rheumatology. 2011, Brighton, UK: Oxford University Press.
• Cooles FAH, Pratt AG, Wilson G, Isaacs JD, Ng WF. Prevalence and diagnostic outcome relating to vitamin D deficiency in new patients presenting to an early arthritis clinic over 12 months. Clinical Rheumatology 2011, 30(8), 1137-1138.
• Juarez MJ, Toms TE, Mitchell S, Bowman S, Ng WF, Price E, Kitas G, UKPRSSR. Prevalence of traditional cardiovascular risk factors in females with primary Sjogrens Syndrome. In: Rheumatology: Annual Meeting of the British Society for Rheumatology. 2011, Brighton, UK: Oxford University Press.
• Dillon SP, Kao L, Kaufman KM, Ice JA, Omdal R, Mariette X, Witte T, Illei GG, Rischmueller M, Nordmark G, Jonsson R, Herlenius MW, Vyse TJ, Brennan MT, Rybicki BA, Ng WF, Segal BM, Rhodus NL, Merrill JT, Montgomery CG, Lessard CJ, Harley JB, Moser KL, Gaffney PM, Scofield RH. Triple X Syndrome (47,XXX) Increases the Risk and Accelerates the Onset of Systemic Lupus Erythematosus and Sjogren's Syndrome: Support for a Gene-Dose Effect From the X Chromosome. In: Arthritis & Rheumatism: 75th Annual Scientific Meeting of the American College of Rheumatology. 2011, Chicago, Illinois, USA: John Wiley & Sons, Inc.
• Ng WF, Bowman SJ, Griffiths B, UKPSSR Study Group. United Kingdom Primary Sjogren's Syndrome Registry - a united effort to tackle an orphan rheumatic disease. Rheumatology 2011, 50(1), 32-39.
• Hassan B, Maxwell JR, Hyrich KL, Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate, Barton A, Worthington J, Isaacs JD, Morgan AW, Wilson AG. Genotype at the sIL-6R A358C polymorphism does not influence response to anti-TNF therapy in patients with rheumatoid arthritis. Rheumatology 2010, 49(1), 43-47.
• Ng WF, von Delwig A, Carmichael AJ, Arkwright PD, Abinun M, Cant AJ, Jolles S, Lilic D. Impaired T_H17 responses in patients with chronic mucocutaneous candidiasis with and without autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy. Journal of Allergy and Clinical Immunology 2010, 126(5), 1006-1015.
• Ng WF, Bowman SJ. Primary Sjogren's syndrome: too dry and too tired. Rheumatology 2010, 49(5), 844-853.
• Tudhope SJ, von Delwig A, Falconer J, Pratt A, Woolridge T, Wilson G, Isaacs JD, Ng WF. Profound invariant natural killer T-cell deficiency in inflammatory arthritis. Annals of the Rheumatic Diseases 2010, 69(10), 1873-1879.
• von Delwig A, Locke J, Robinson JH, Ng WF. Response of Th17 Cells to a Citrullinated Arthritogenic Aggrecan Peptide in Patients With Rheumatoid Arthritis. Arthritis & Rheumatism 2010, 62(1), 143-149.
• Bracewell C, Isaacs JD, Emery P, Ng WF. Atacicept, a novel B cell-targeting biological therapy for the treatment of rheumatoid arthritis. Expert Opinion on Biological Therapy 2009, 9(7), 909-919.
• Raychaudhuri S, Thomson BP, Remmers EF, Eyre S, Hinks A, Guiducci C, Catanese JJ, Xie G, Stahl EA, Chen R, Alfredsson L, Amos CI, Ardlie KG, BIRAC Consortium, Barton A, Bowes J, Burtt NP, Chang M, Coblyn J, Costenbader KH, Criswell LA, Crusius JB, Cui J, DeJager PL, Ding B, Emery P, Flynn E, Harrison P, Hocking LJ, Huizinga TW, Kastner DL, Ke X, Kurreeman FA, Lee AT, Liu X, Li Y, Martin P, Morgan AW, Padyukov L, Reid DM, Seielstad M, Seldin MF, Shadick NA, Steer S, Tak PP, Thomson W, vanderHelm-vanMil AH, vanderHorst-Bruinsma IE, Weinblatt ME, Wilson AG, Wolbink GJ, Wordsworth P, YEAR Consortium, Altshuler D, Karlson EW, Toes RE, deVries N, Begovich AB, Siminovitch KA, Worthington J, Klareskog L, Gregersen PK, Daly MJ, Plenge RM. Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk. Nature Genetics 2009, 41(12), 1313-1318.
• Godkin A, Ng WF, Gallagher K, Betts G, Thomas HC, Lechler RI. Expansion of hepatitis C-specific CD4⁺CD25⁺ regulatory T cells after viral clearance: A mechanism to limit collateral damage?. Journal of Allergy and Clinical Immunology 2008, 121(5), 1277-1284.
• Datta HK, Ng WF, Walker JA, Tuck SP, Varanasi SS. The cell biology of bone metabolism. Journal of Clinical Pathology 2008, 61(5), 577-587.
• Ng W-F, Naughton M. Fluoroquinolone-associated tendinopathy: A case report. Journal of Medical Case Reports 2007, 1(55).
• Ng WF, Isaacs JD. From mice to men: the challenges of developing tolerance-inducing biological drugs for the clinic. In: Graca, L, ed. The Immune Synapse as a Novel Target for Therapy. Basel-Boston-Berlin: Birkhauser Verlar AG, 2007, pp.169-185.
• Ng WF, Isaacs JD. From mice to men: the challenges of developing tolerance-inducing biological drugs for the clinic. In: Graca, L, ed. The Immune Synapse as a Novel Target for Therapy. Basel-Boston-Berlin: Birkhauser Verlag AG, 2007, pp.169-186.
• Hepburn AL, Lampert IA, Boyle JJ, Horncastle D, Ng WF, Layton M, Vyse TJ, Botto M, Mason JC. In vivo evidence for apoptosis in the bone marrow in systemic lupus erythematosus. Annals of the Rheumatic Diseases 2007, 66(8), 1106-1109.
• Ng WF, Fantin F, Ng C, Dockery F, Schiff R, Davies KA, Rajkumar C, Mason JC. Takayasu's arteritis: a cause of prolonged arterial stiffness. Rheumatology 2006, 45(6), 741-745.
• Ng WF, Cohen P, Hepburn A, Hamdulay S, Carpani M, Mason JC. A case of eosinophilic enteritis and rheumatoid arthritis. Rheumatology 2005, 44(12), 1585-1586.
• Bonnefoix T, Bonnefoix P, Perron P, Mi JQ, Ng WF, Lechler R, Bensa JC, Cahn JY, Leroux D. Quantitating Effector and Regulatory T Lymphocytes in Immune Responses by Limiting Dilution Analysis Modeling. Journal of Immunology 2005, 174(6), 3421-3431.
• Ng WF, Demetriadi F, Hall A, Steuer A. [abstract] Mesenteric Inflammatory veno-occlusive disease. Rheumatology 2003, 42(s1), 109.
• Schneider H, Mandelbrot DA, Greenwald RJ, Ng F, Lechler R, Sharpe AH, Rudd CE. Cutting Edge: CTLA-4 (CD152) Differentially Regulates Mitogen-Activated Protein Kinases (Extracellular Signal-Regulated Kinase and c-Jun N-Terminal Kinase) in CD4⁺ T Cells from Receptor/Ligand-Deficient Mice. The Journal of Immunology 2002, 169(7), 3475-3479.
• Camara NO, Ng WF, Hernandes-Fuentes M, Eren E, Lechler RI. Human CD4+ CD25+ T cells regulate CD8+ T-cell activation. Transplantation Proceedings 2002, 34(7), 2858-2860.
• Ng WF, Hernandez-Fuentes M, Baker R, Chaudhry A, Lechler RI. Reversibility with Interleukin-2 Suggests that T Cell Anergy Contributes to Donor-Specific Hyporesponsiveness in Renal Transplant Patients. Journal of the American Society of Nephrology 2002, 13(12), 2983-2989.
• Lechler R, Ng WF, Steinman RM. Dendritic cells in transplantation--friend or foe?. Immunity 2001, 14(4), 357-368.
• Ng WF, Duggan PJ, Ponchel F, Matarese G, Lombardi G, Edwards AD, Isaacs JD, Lechler RI. Human CD4⁺CD25⁺ cells: a naturally occurring population of regulatory T cells. Blood 2001, 98(9), 2736-2744.
• Lechler RI, Ng WF, Camara NO. Infectious tolerance? Mechanisms and implications. Transplantation 2001, 72(8 Suppl), S29-31.
• Ng WF, Hernandez-Fuentes MP, Lombardi G. Predictive value of in vitro assessment of direct alloresponses in transplant recipients? (Comment on Transplantation. 2001 Sep 15;72(5):873-80). Transplantation 2001, 72(5), 772-773.
• Ng WF, Baker RJ, Hernandez-Fuentes M, Chaudhry A, Lechler RI. The role of T-cell anergy in the maintenance of donor-specific hyporesponsiveness in renal transplant recipients. Transplantation Proceedings 2001, 33(1-2), 154-155.