Publications
The following list of papers shows the range of research carried out by users of the Bio Screening Facility
Acknowledging the Facility
If you've used our Facility, please recognise and acknowledge it in your publications and grant applications. Although you pay to use the Facility, the full cost of any scientific core facility is not passed on to the end user.
The Faculty of Medical Sciences look at the quantity and quality of publications from the University research themes containing data with direct links to the BioScreening usage. This is used as a metric of facility performance (alongside the number of usage hours and cost recovery).
Acknowledging the BioScreening Facility in your papers, posters and talks will help to ensure we continue to receive faculty subsidy and continue to offer excellent access rates.
Using data generated within the BioScreening Facility
In a publication that includes data (main figures or supplemental) generated within the BioScreening Facility, please state:
“We acknowledge the Newcastle University BioScreening Facility for assistance with the generation of data”.
Working closely with BioScreening staff members
If a member of the BioScreening team has worked closely with you on a project, you should acknowledge this.
It is good practice to include their name in the acknowledgement section at least.
In situations where they have made substantial intellectual input, you can offer them a co-authorship. This should be discussed at the earliest opportunity.
Published in 2026
- Islam, I., Wilson, J., Clegg, A., Hancock, H., Martin-Ruiz, C., McDonald, C., Sayer, A., Steves, C., von Zglinicki, T. and Witham, M. (2026) '3778 Effects of metformin on biomarkers in older people with sarcopenia: analysis from the MET-PREVENT randomised controlled trial', Age and Ageing, 55(Sup).
Published in 2025
- Mlakar, V., Di Forti, M., Halff, E. F., Srivastava, D. P., Akkouh, I., Djurovic, S., Martin-Ruiz, C., Quintana, D. S., Birkenæs, V. and Steen, N. E. (2025) 'Coffee intake is associated with telomere length in severe mental disorders', BMJ Mental Health, 28(1).
- Perri, G., French, C., Agostinis-Sobrinho, C., Anand, A., Antarianto, R. D., Arai, Y., Baur, J. A., Cauli, O., Clivaz-Duc, M. and Colloca, G. (2025) 'An expert consensus statement on biomarkers of aging for use in intervention studies', The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences, 80(5), pp. glae297.
- Spray, L., Mcintosh, A., Mccartney, P., Martin-Ruiz, C., White, S., Berry, C. and Spyridopoulos, I. (2025) 'Cigarette smoking and release of the inflammatory chemokine CXCL10 (IP-10) after ST-elevation myocardial infarction', European Heart Journal, 46(Supplement_1), pp. ehaf784. 1890.
- Mlakar, V., Di Forti, M., Halff, E., Srivastava, D., Djurovic, S., Martin-Ruiz, C., Quintana, D., Birkenæs, V., Steen, N. E. and Ormerod, M. (2025) 'Health behaviours and telomere length in severe mental disorders'.
Published in 2024
- Camacho-Encina, M., Booth, L. K., Redgrave, R., Honkanen-Scott, M., Scott III, W. E., Martin-Ruiz, C., MacGowan, G., Richardson, S., Dark, J. and Tual-Chalot, S. (2024) 'Identifying optimal reference genes for real-time quantitative polymerase chain reaction in human myocardial tissues', Cardiovascular Research, 120(17), pp. 2163–2165.
- Dirjayanto, V. J., Martin-Ruiz, C., Pompei, G., Rubino, F. and Kunadian, V. (2024) 'The association of inflammatory biomarkers and long-term clinical outcomes in older adults with non-ST elevation acute coronary syndrome', International Journal of Cardiology, 409, pp. 132177.
- Perri, G., Mathers, J., Martin-Ruiz, C., Parker, C., Demircan, K., Chillon, T., Schomburg, L., Robinson, L., Stevenson, E. and Terrera, G. (2024a) 'The association between selenium status and cognitive decline in very old adults: The Newcastle 85+ Study', Proceedings of the Nutrition Society, 83(OCE2), pp. E200.
- Perri, G., Mathers, J. C., Martin-Ruiz, C., Parker, C., Demircan, K., Chillon, T. S., Schomburg, L., Robinson, L., Stevenson, E. J. and Shannon, O. M. (2024b) 'The association between selenium status and global and attention-specific cognition in very old adults in the Newcastle 85+ Study: Cross-sectional and longitudinal analyses', The American Journal of Clinical Nutrition, 120(5), pp. 1019–1028.
Published in 2023
- Taylor R, Barnes AC, Hollingsworth KG, Irvine KM, Solovyova AS, Clark L, et al. Aetiology of Type 2 diabetes in people with a 'normal' body mass index: testing the personal fat threshold hypothesis. Clin Sci (Lond). 2023;137(16):1333-46.
- Perri G, Mathers JC, Martin-Ruiz C, Walsh JS, Eastell R, Schomburg L, et al. Selenium status in very old adults: Insights from the Newcastle 85+Study. P Nutr Soc. 2023;82(Oce3).
- Perri G, Mathers JC, Martin-Ruiz C, Parker C, Walsh JS, Eastell R, et al. Selenium status and its determinants in very old adults: insights from the Newcastle 85+ Study. Br J Nutr. 2023:1-10.
- Mlakar V, Birkenaes V, Elvsaashagen T, Ormerod M, Quintana DS, Ueland T, et al. Telomere length and verbal learning in bipolar disorders. J Affect Disord. 2023;339:555-60.
- Booth L, Redgrave R, Camacho Encina M, Tual-Chalot S, Folaranmi O, Martin-Ruiz C, et al. The senescence-associated secretory phenotype as
Published in 2022
- Wright JR, Deen QFE, Stevenson A, Telford-Cooke LL, Parker C, Martin-Ruiz C, et al. Plasma Myeloperoxidase as a Potential Biomarker of Patient Response to Anti-Dementia Treatment in Alzheimer's Disease. J Alzheimers Dis. 2022;89(4):1483-92.
- Tinlin-Mackenzie A, Ellis CD, Lodola A, Martin-Ruiz C, Stevens JR, Fitzsimmons C. New kid on the block: first record of juvenile American lobster, H. Milne Edwards, 1837, in European waters. Bioinvasions Rec. 2022;11(4):991-1000.
- Taylor R, Barnes AC, Irvine KM, Clark L, Al-Mrabeh A, Solovyova A, et al. Diabetes remission by weight loss in 'normal' weight people with type 2 diabetes: the ReTUNE study. Diabetologia. 2022;65(Suppl 1):S135-S.
- Hoffmann J, Tabata N, Mas-Peiro S, Spyridopoulos I, Sinning JM, Berkowitsch A, et al. Longer leukocyte telomere length is associated with myeloid inflammation and increased mortality after transcatheter aortic valve replacement. Eur Heart J Open. 2022;2(4):oeac045.
- Granic A, Martin-Ruiz C, Rimmer L, Dodds RM, Robinson LA, Spyridopoulos I, et al. Immunosenescence profiles of lymphocyte compartments and multiple long-term conditions (multimorbidity) in very old adults: The Newcastle 85+ Study. Mech Ageing Dev. 2022;208:111739.
- Granic A, Martin-Ruiz C, Rimmer L, Dodds RM, Robinson L, Spyridopoulos I, et al. Immunosenescence Profiles and Multiple Long-Term Conditions in Very Old Adults: The Newcastle 85+Study. Age and Ageing. 2022;51(Suppl 2).
- Donaghy PC, Cockell SJ, Martin-Ruiz C, Coxhead J, Kane J, Erskine D, et al. Blood mRNA Expression in Alzheimer's Disease and Dementia With Lewy Bodies. Am J Geriatr Psychiatry. 2022;30(9):964-75.
- Amin HA, Cordell HJ, Martin-Ruiz C, Robinson L, Kirkwood T, Blakemore AI, et al. No Evidence That Genetic Variation at the Klotho Locus Is Associated With Longevity in Caucasians from the Newcastle 85+ Study and the UK Biobank. J Gerontol A Biol Sci Med Sci. 2022;77(3):457-61.
Published in 2021
- Oliver M. Shannon, Ammar W. Ashor, Filippo Scialo, Gabriele Saretzki, Carmen Martin-Ruiz, Jose Lara, Jamie Matu,Alex Griffiths,Natassia Robinson,Lionetti Lillà, Emma Stevenson, Blossom C. M. Stephan, Anne Marie Minihane, Mario Siervo, John C. Mathers Mediterranean diet and the hallmarks of ageing, Eur J Clin Nut., Jan 2021.
- Anaemia and physical and mental health in the very old: An individual participant data meta-analysis of four longitudinal studies of ageing Age Ageing. Jan 2021
Published in 2020
- D. Chan, C. Martin-Ruiz, G. Saretzki, D. Neely, W. Qiu, and V. Kunadian. The association of telomere length and telomerase activity with adverse outcomes in older patients with non-ST-elevation acute coronary syndrome (in eng) PLoS One Jan 2020
- Prospective Longitudinal Evaluation of Cytokines in mild cognitive impairment due to AD and Lewy Body Disease (in eng) Int J Geriatr Psychiatry. Jun 19 2020.
- Martin-Ruiz, Carmena, Williams-Gray, Caroline H. Yarnall, Alison J Boucher, John J. Lawson, Rachael A. Wijeyekoon, Ruwani S. Barker, Roger A. Kolenda, Claire Parker, Craig, Burn, David, Von Zglinicki, Thomase, Saretzki Gabriel, Senescence and Inflammatory Markers for Predicting Clinical Progression in Parkinson's Disease: The ICICLE-PD Study (in eng) J Parkinsons Dis, Jan 2020
- CMV-independent increase in CD27-CD28+ CD8+ EMRA T cells is inversely related to mortality in octogenarians (in eng), NPJ Aging Mech Dis Jan 2020
- Immunosenescence profiles are not associated with muscle strength, physical performance and sarcopenia risk in very old adults: The Newcastle 85+ Study Mech Ageing Dev, Sept 2020
Published in 2019
- Plasma Vitamin B12, Supplementation and Mortality, J Gerontol A Biol Sci Med Sci. Jan 2019
- Peripheral inflammation in mild cognitive impairment with possible and probable Lewy body disease and Alzheimer's disease (in eng), Int Psychogeriatr April 2019
- Inflammation in mild cognitive impairment due to Parkinson's disease, Lewy body disease, and Alzheimer's disease (in eng), Int J Geriatr Psychiatry. April 2019
- J. Deelen et al., A meta-analysis of genome-wide association studies identifies multiple longevity genes, (in eng), Nat Commun, Aug 2019.
- S. Boag, E. Andreano, C. Martin-Ruiz, and I. Spyridopoulos, Role of Immunosenescence in Coronary Artery Disease, in Handbook of Immunosenescence: Basic Understanding and Clinical Implications. May 2019
- Smoking does not accelerate leucocyte telomere attrition: a meta-analysis of 18 longitudinal cohorts (in eng), R Soc Open Sci, Jun 2019.
- M. Aas et al., Telomere Length is associated with childhood trauma in patients with severe mental disorders. Schizophrenia Bulletin, March 2019.
Published in 2018
- N. Mendonca et al., Elevated Total Homocysteine in All Participants and Plasma Vitamin B12 Concentrations in Women Are Associated With All-Cause and Cardiovascular Mortality in the Very Old: The Newcastle 85+ Study, J Gerontol A Biol Sci Med Sci. Aug 2018
- R. E. Marioni et al., The epigenetic clock and telomere length are independently associated with chronological age and mortality, Int J Epidemiol. Feb 1 2018.
- E. King et al., Peripheral inflammation in prodromal Alzheimer's and Lewy body dementias, J Neurol Neurosurg Psychiatry, Apr 2018.
Published in 2017
- D. Nettle et al., Early-life adversity accelerates cellular ageing and affects adult inflammation: Experimental evidence from the European starling, Sci Rep. Jan 17 2017.
- N. Mendonca et al., One-Carbon Metabolism Biomarkers and Cognitive Decline in the Very Old: The Newcastle 85+ Study, J Am Med Dir Assoc. Sep 2017
- N. Mendonca et al., Homocysteine, Tryptophan, and Cognition in the Very Old, J Am Med Dir Assoc, Oct 2017.
- K. E. McAleese et al., Parietal white matter lesions in Alzheimer's disease are associated with cortical neurodegenerative pathology, but not with small vessel disease, Acta Neuropathol, Sep 2017.
- S. E. Harris et al., Age-related gene expression changes, and transcriptome wide association study of physical and cognitive aging traits, in the Lothian Birth Cohort 1936, Aging (Albany NY), Dec 1 2017.
- A. Granic et al., Grip strength and inflammatory biomarker profiles in very old adults, Age Ageing, Nov 1 2017.
Published in 2016
- I. Spyridopoulos et al., CMV seropositivity and T-cell senescence predict increased cardiovascular mortality in octogenarians: results from the Newcastle 85+ study, Aging Cell, April 2016
- S. H. Pearce et al., Serum Thyroid Function, Mortality and Disability in Advanced Old Age: The Newcastle 85+ Study, J Clin Endocrinol Metab, Nov 2016.
- D. Nettle et al., Brood size moderates associations between relative size, telomere length, and immune development in European starling nestlings Ecol Evol, Nov 2016
- N. Mendonca et al., Intakes of Folate and Vitamin B12 and Biomarkers of Status in the Very Old: The Newcastle 85+ Study, Nutrients, Sep 28 2016.
- R. E. Marioni et al., The epigenetic clock and telomere length are independently associated with chronological age and mortality, Int J Epidemiol, Apr 13 2016.
- T. R. Hill et al., Serum 25-hydroxyvitamin D concentration and its determinants in the very old: the Newcastle 85+ Study, Osteoporos Int, March 2016.
- S. E. Harris et al., Longitudinal telomere length shortening and cognitive and physical decline in later life: The Lothian Birth Cohorts 1936 and 1921 Mech Ageing Dev. March 2016
- Ikeh MA et al., Pho4 mediates phosphate acquisition in Candida albicans and is vital for stress resistance and metal homeostasis. Molecular Biology of the Cell 2016
Published in 2015
- L. Walker et al., Neuropathologically mixed Alzheimer's and Lewy body disease: burden of pathological protein aggregates differs between clinical phenotypes Acta Neuropathol, May 2015.
- A. Mitnitski et al., Age-related frailty and its association with biological markers of ageing BMC Med, Jul 13 2015.
- N. G. Masca et al., RIPOSTE: a framework for improving the design and analysis of laboratory-based research, Elife May 7 2015.
- C. M. Martin-Ruiz et al., Reproducibility of telomere length assessment: an international collaborative study, Int J Epidemiol, Oct 2015.
- C. M. Martin-Ruiz et al., Reproducibility of Telomere Length Assessment--An International Collaborative Study, Int J Epidemiol, Oct 2015.
- C. M. Martin-Ruiz et al., Reproducibility of telomere length assessment: Authors' Response to Damjan Krstajic and Ljubomir Buturovic Int J Epidemiol, Oct 2015.
- A. Granic et al., Serum 25-hydroxyvitamin D and cognitive decline in the very old: the Newcastle 85+ Study, Eur J Neurol, Jan 2015.
- A. Granic et al., 25-hydroxyvitamin D and increased all-cause mortality in very old women: the Newcastle 85+ study, J Intern Med, Apr 2015.
- Y. Arai et al., Inflammation, But Not Telomere Length, Predicts Successful Ageing at Extreme Old Age: A Longitudinal Study of Semi-supercentenarians, EBioMedicine, July 2015
- Dubarry M, Lawless C, Banks AP, Cockell S, Lydall D. Genetic Networks Required to Coordinate Chromosome Replication by DNA Polymerases α, δ, and ε in Saccharomyces cerevisiae. G3: Genes, Genomes, Genetics August 2015.
- Narayanan S, Dubarry M, Lawless C, Banks AP, Wilkinson DJ, Whitehall SK, Lydall D. Quantitative Fitness Analysis Identifies exo1∆ and Other Suppressors or Enhancers of Telomere Defects in Schizosaccharomyces pombe. PloS ONE July 2015
Published in 2014
- L. Wiley et al., Reactive oxygen species production and mitochondrial dysfunction in white blood cells are not valid biomarkers of ageing in the very old, PLoS One, March 2014
- S. Masi et al., Rate of telomere shortening and cardiovascular damage: a longitudinal study in the 1946 British Birth Cohort, Eur Heart J, Dec 7 2014.
- C. Martin-Ruiz and T. von Zglinicki, Biomarkers of healthy ageing: expectations and validation, Proc Nutr Soc. Aug 2014.
- M. Gardner et al., Gender and telomere length: systematic review and meta-analysis, Exp Gerontol, Mar 2014.
- J. Deelen et al., Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age, Hum Mol Genet, August 2014.
- J. Collerton et al., Utility of NT-proBNP as a rule-out test for left ventricular dysfunction in very old people with limiting dyspnoea: the Newcastle 85+ Study, BMC Cardiovasc Disord, Sept 2014.
- J. Collerton et al., Acquisition of aberrant DNA methylation is associated with frailty in the very old: findings from the Newcastle 85+ Study, Biogerontology, August 2014.
- D. Baylis et al., Inflammation, telomere length, and grip strength: a 10-year longitudinal study, Calcif Tissue Int, Jul 2014.