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Genomics Core Facility

State of the art next-generation sequencing, specialising in single cell.

About us

Located at the International Centre for Life, within Newcastle University’s Biosciences Institute, the Genomics Core Facility (GCF) is a state of the art next-generation sequencing (NGS) service provider specialising in single-cell applications.

Our team has extensive experience in project management and service delivery. This comes from a background working with customers in the academic, commercial, and healthcare sectors. 

Established by Dr Jonathan Coxhead in 2015, the GCF's role is to ensure that Newcastle University remains at the forefront of genomics research. This is at both the macro and single-cell level.

Our genomics research is supported by the fabulous work of the NU Genomics Core. We love to work with them as the quality of their service is of the highest standards and they are very open to plan the work with us and implement novel approaches.

Joris Veltman, Professor of Personalized Medicine, Dean of Biosciences Institute, Newcastle University

Single-Cell and Spatial Transcriptomics

Our single-cell applications are focussed around the 10X Genomics Chromium platform, plate-based methods, and enrichment using laser capture micro-dissection (LMD). As one of the first groups in the UK to adopt spatial gene expression profiling, we offer 'Spatially Resolved Transcriptomics At Newcastle' (SpaRTAN) as a 'first in Europe' 10X Genomics Certified Service Provider.

Scalable Technologies and Applications

All of our platforms offer scalable solutions, providing the flexibility to work with us on everything from small proof-of-principle experiments through to large discovery research projects or programme scale studies. Our instruments include next-generation sequencing, real-time PCR, and droplet digital PCR.

Commitment to Excellence

Every project begins with a clear plan following consultation with th team, ensuring optimal experimental design relevant to the biological questions being investigated, and budget availability. Our commitment to clear communication is assured throughout the lifespan of a project and at every stage of sample processing, from QC through to data delivery.