Global Opportunities

BMN2006 : Cell Biology and Disease

Semesters
Semester 1 Credit Value: 20
ECTS Credits: 10.0

Aims

Through this module the student will gain greater understanding of aspects of Cell Biology focusing on post-translational events and how cellular events lead to normal tissue function or disease development. Lectures, small groups and practical work will be used to develop a greater understanding of how the mechanisms within individual cells and between cells impact on tissues and therefore the organism. The module will employ a case study approach looking at the impact of mechanistic dysfunction on various conditions such as diabetes, heart disease and cancer.

Outline Of Syllabus

The students will study the following cellular processes:
•       Proteins: post-translational processing and trafficking,
•       Membrane transport and ion channels,
•       Extracellular matrix,
•       Cell Signalling,
•       Cell cycle.
Disease case studies will be used to illustrate the effect of dysfunction in each of these processes.

Teaching Methods

Teaching Activities
Category Activity Number Length Student Hours Comment
Scheduled Learning And Teaching ActivitiesLecture71:007:00Synchronous online (30%)
Guided Independent StudyAssessment preparation and completion11:001:00PIP - Feedback session on poster preparation from the material gathered in the practical
Scheduled Learning And Teaching ActivitiesLecture11:001:00PIP - introduction to the module
Scheduled Learning And Teaching ActivitiesLecture171:0017:00PIP lectures (70%)
Scheduled Learning And Teaching ActivitiesPractical11:301:30PIP - Lab-based practical
Scheduled Learning And Teaching ActivitiesSmall group teaching51:005:00PIP seminars
Guided Independent StudyIndependent study1167:30167:30Writing up lecture notes, revision and general reading.
Total200:00
Teaching Rationale And Relationship

Lectures will be used to provide new detailed information and illustrate the significance of normal and abnormal mechanisms using examples of common diseases (LO K1-3).

A case study approach will be used in seminars to enable students to discuss and gain a deeper understanding of the lecture material (LO K4, S2).

A laboratory-based practical will enhance the students competence in the laboratory and generate a suitable set of data that can be used for assessment purposes (LO S3).

Before and following the practical, two of the seminars will be used to introduce the students to academic posters and then form peer support groups to discuss poster design and their construction to help prepare the student for the assessment.

Students will be expected to use independent study time to read around the subject to gain a greater understanding of the topic (LO S1).

Assessment Methods

The format of resits will be determined by the Board of Examiners

Exams
Description Length Semester When Set Percentage Comment
Written Examination601A40Remote 2hour time-tabled open book essay - 1 question from a choice of 2, 800 words.
Digital Examination601A40PIP Inspera Invigilated: quiz format - max 60 questions
Other Assessment
Description Semester When Set Percentage Comment
Practical/lab report1M20The students will construct an academic poster based on the practical they carry out in the module, equivalent word count <1000
Assessment Rationale And Relationship

There will be two assessments - a practical report and an exam.

Exam:
The quiz format and written examination will assess the students' knowledge and understanding of taught material and additional reading.

Practical Report:
Students will construct an academic poster to present the methodologies, findings and data analysis of the practical carried out during the module.

Reading Lists

Timetable