Study Abroad and Exchanges



PED3005 : Advanced Pharmacogenetics

Semester 1 Credit Value: 10
ECTS Credits: 5.0


To provide information on how genetic factors affect the methabolism of foregin compounds and drug-receptor interactions, an appreciation of current views on the relationship between pharmacogenetic polymorphisms and disease suseptiability, potential approaches to drug design using pharmacogenics and introduction to molecular epidemiology

Original Summary:
This module will cover aspects of genetic factors that affect the metabolism of foreign compounds and drug-receptor interactions. Lectures address current views on the relationship between pharmacogenetic polymorphisms and disease susceptibility and potential approaches to drug design using pharmacogenomics and provide an introduction to molecular epidemiology. You will develop a knowledge and understanding of the molecular basis of polymorphisms in drug metabolizing enzymes, including the cytochromes P450, the glutathione S-transferases and N-acetyltransferases, the importance of inter-individual variability in drug metabolism in the drug development process and in therapeutics, polymorphisms in drug receptors and other drug targets and the relationship between genetic polymorphisms and disease susceptibility.

The module comprises of Lectures and seminars and practicals.
Assessment is based on in-course assessment (20%) and written examination (80%).

Outline Of Syllabus

See above.

Teaching Methods

Teaching Activities
Category Activity Number Length Student Hours Comment
Guided Independent StudyAssessment preparation and completion11:001:00EMI
Scheduled Learning And Teaching ActivitiesLecture13:003:00Group learning
Scheduled Learning And Teaching ActivitiesLecture141:0014:00N/A
Scheduled Learning And Teaching ActivitiesSmall group teaching21:002:00Seminars
Guided Independent StudyIndependent study180:0080:00Private study
Teaching Rationale And Relationship


Assessment Methods

The format of resits will be determined by the Board of Examiners

Description Length Semester When Set Percentage Comment
Written Examination902A80N/A
Other Assessment
Description Semester When Set Percentage Comment
Prob solv exercises1M10EMI
Prof skill assessmnt1M10Oral presentation
Assessment Rationale And Relationship

This is an advanced course involving reading of research as well as advanced textbooks. A presentation on a relevant paper is used to assess understanding and advanced reading with the unseen examination ensuring that students have a knowledge of the basic principles

FMS Schools offering Semester One modules available as ‘Study Abroad’ will, where required, provide an alternative assessment time for examinations that take place after the Christmas vacation. Coursework with submissions dates after the Christmas vacation will either be submitted at an earlier date or at the same time remotely.

The form of assessment will not vary from the original.

Reading Lists