Newcastle University Protein and Proteome Analysis
NUPPA
Who we are
This core facility was set up to support researchers' protein and proteome analysis needs within and outside of the University.
Our main focus is protein science: protein purification, protein identification and quantification, mass, size, shape, and the interactions of proteins.
We are also experienced in a wider range of biomolecules (such as carbohydrates or nucleic acids).
We provide support to internal researchers as well as external academic and commercial organisations.
How to submit a sample
To start a new project or submit a sample for analysis with NUPPA, or request accurate pricing, please contact us via email and be sure to include a contact for the appropriate unit to ensure most efficient response. Sample submission forms can be found here.
Key grants
Key Grants which underpin the facility:
- 2014-present: Taggart Group MRC, Cardiac Research (£728k) (_Proteomics_)
- 2018-2022: James Guest CoralAssist (>£1M) (_Proteomics_)
- 2017-2022: Grant Burgess Hereus NucB (£400K) (_ProteinProduction_)
- 2016-2019: John Issacs Rheumatoid Arthritis (£400K)(_Proteomics_)
- 2016-2020: Phil Brown Methotrexate Quantification (_Proteomics_)
Recent Publications
Tinning H, Taylor A, Wang D, Constantinides B, Sutton R, Oikonomou G, Velazquez MA, Thompson P, Treumann A, O'Connell MJ, Forde N. The role of CAPG in molecular communication between the embryo and the uterine endometrium: Is its function conserved in species with different implantation strategies? FASEB J. 2020 Jul 3. doi: 10.1096/fj.202000882RR. (Epub ahead of print) PMID: 32619075.
Lence E, Maneiro M, Sanz-Gaitero M, van Raaij MJ, Thompson P, Hawkins AR, González-Bello C. Self-Immolation of a Bacterial Dehydratase Enzyme by its Epoxide Product. Chemistry. 2020 Jun 26;26(36):8035-8044. doi: 10.1002/chem.202000759. Epub 2020 Jun 8. PMID: 32259333
Verheul, J. Yau H. LLodge A, Liu X., Solovyova AS, Typas A, Banzhaf M., Vollmer W, den Blaauwen T..Midcell localization of PBP4 of Escherichia coli is essential for the timing of the divisome (2020) submitted