Staff Profile
Dr Jake McClements
NUAcT Fellow: Ageing and Health
- Address: Bedson Building
School of Engineering
Newcastle University
Newcastle upon Tyne, NE1 7RU
United Kingdom
Background
I was awarded a degree in Physics from the University of Leeds and subsequently pursued a PhD at the University of Edinburgh in conjunction with the Soft Matter and Functional Interfaces CDT. My doctoral research project focused on characterising the interactions between polymers and nanomaterials at different length scales. Upon completion of my PhD, I remained at the University of Edinburgh as a Research Associate for one year. My project involved working closely with Michelin to investigate the interactions between carbon nanoparticles and latex thin films, which has fundamental importance, as well as being highly relevant to the composite materials industry. In 2020, I began a Research Associate position at Newcastle University, where I used my expertise in soft materials to develop polymer-based biosensors for the diagnosis of various conditions and illnesses, including cardiovascular diseases, foodborne diseases, and SARS-CoV-2.
In 2023, I was awarded a Newcastle University Academic Track (NUAcT) Fellowship. My research group develops polymeric recognition elements and associated sensors for a range of diagnostic and industrial applications, with a particular focus on next-generation wearable and point-of-care devices that use minimally invasive sampling methods, such as interstitial fluid extraction. Beyond research, I also serve as an Editor for the Elsevier journal Sustainable Materials and Technologies.
To find out more about my research, please see the links below:
Research Focus
My primary research focus is developing next-generation biosensors for various health and industrial applications. To achieve this, I often utilise synthetic receptors such as molecularly imprinted polymers, as well as low-cost screen-printed electrodes and 3D-printed measurement cells. I explore electrochemical, thermal, and optical detection methods and use multiple analytical techniques for characterisation, including surface plasmon resonance and atomic force microscopy. My ultimate objective is to create non-invasive wearable or point-of-care sensors for closely monitoring serious health conditions.
Research Interests
- Biosensors for health and industrial applications
- Wearable sensors for the diagnosis and tracking of health conditions
- Atomic force microscopy of soft materials
- Interfacial behaviour in soft matter systems
- Additive manufacturing
Research Funding
2025 EPSRC: Impact Acceleration Account, £10K, PI
2025 NIHR Newcastle BRC: Interdisciplinary Research Project, £10K, Co-I
2024 EPSRC NortHFutures, £50K, PI
2024 RSC Sustainable Laboratories Grant, £10K, PI
2023 Northern Accelerator: Feasibility Grant, £10K, PI
2023 EPSRC Innovation to Impact, £45K, Co-I
2023 Translational Explorer Scheme, Newcastle WTTP, £10K, Co-I
2021 Nanotechnology Scheme, United States Department of Agriculture, £545K, Co-I
2021 EPSRC Impact Acceleration Account, £20K, Co-I
2021 RSC Analytical Chemistry Summer Studentships, £2K, PI
Professional Memberships
- Royal Society of Chemistry
- Institution of Chemical Engineers
Media Appearances
- Want to be a Successful Scientist? The McClements Family has some Tips, Scienmag, 31 May 2024
- How to Build-a-Bear out of Recycled Plastic, Royal Academy of Engineering, 17 Apr 2023
- Scientists Develop Portable Sensor Technology to Detect Foodborne Contaminants Outside the Lab, AZO Sensors, 6 Jun 2022
- Portable Sensor Technology Aims to Quickly Detect Foodborne Contaminants Outside the Lab, UMass Amherst, 3 Jun 2022
- MIP Diagnostics see COVID-19 Molecularly Imprinted Polymers as ‘Showcase’ for Company’s Future, 360Dx, 13 May 2022
- Tyneside Scientists Develop ‘More Accurate’ Rapid COVID-19 Tests, Chronicle Live, 14 Apr, 2022
- New COVID-19 Rapid Test Said to Be More Sensitive Than Any Other, Newsweek, 13 Apr 2022
- This Could Be Our Fastest, Most Sensitive COVID Test Yet, Yahoo News, 13 Apr 2022
Citizenship
- Editor for the Elsevier journal Sustainable Materials and Technologies
- Open Research Champion, School of Engineering, Newcastle University
- Research Associate Champion, School of Engineering, Newcastle University
- Associate Editor for the Journal of Nanomaterials, Nanoengineering and Nanosystems (Sage). 2023 - 2025
Public Engagement
- Dream Big for Engineering Scheme, The National Literacy Trust
- Build-a-Bear 2.0 at the Life Science Centre, RAEng Ingenious Grant
- Pint of Science Public Talk, Can we Diagnose Heart Attacks with a Thermometer?
- Meet the Scientist, Dr Jake McClements
Current Teaching
- CME1029 - Chemistry for Chemical Engineers
- CME8097 - Chemical Engineering Dissertation
- CME8128 - MEng Research Project
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Articles
- Saczek J, Dann A, Crapnell RD, Banks CE, Johnson RE, Canfarotta F, Czulak J, Thomson A, Zaman A, Spyridopoulos I, Novakovic K, Peeters M, McClements J. Unlocking interstitial fluid for acute coronary syndrome diagnosis: ultrasensitive troponin I detection using imprinted polymer nanoparticles. Nanoscale Horizons 2026, 11(3), 803-816.
- Jamieson O, Dann A, Liu X, Oliveira Abib T, Novakovic K, McClements J, Seyedin S, Gruber J, Crapnell RD, Snyder H, Banks CE, Dawson JA, Peeters M. Label-free electrochemical levodopa detection via dummy imprinted polymers for advanced disease monitoring. Analytica Chimica Acta 2026, 1393, 345174.
- Lee R, Hall EK, Aljohani BA, McClements J, Peeters M, Geoghegan M. Elastic modulus of hyaluronic acid hydrogels by compression testing. Journal of Materials Science: Materials in Medicine 2025, 36(1), 59.
- Dann A, Singla P, McClements J, Kim M, Stoufer S, Crapnell RD, Banks CE, Seyedin S, Geoghegan M, Blanford CF, Moore MD, Peeters M. Dual strain detection of norovirus GI.1 and GII.4 in food samples using epitope-imprinted polymers. Analytica Chimica Acta 2025, 1368, 344331.
- Prabhu A, Crapnell R, Eersels K, van Grinsven B, Kunhiraman A, Singla P, McClements J, Banks C, Novakovic K, Peeters M. Reviewing the use of chitosan and polydopamine for electrochemical sensing. Current Opinion in Electrochemistry 2022, 32, 100885.
- Noguchi H, Kaur S, Krettli L, Singla P, McClements J, Snyder H, Crapnell R, Banks C, Novakovic K, Kaur I, Gruber J, Dawson J, Peeters M. Rapid electrochemical detection of levodopa using polyaniline-modified screen-printed electrodes for the improved management of Parkinson’s disease. Physics in Medicine 2022, 14, 100052.
- McClements J, Bar L, Singla P, Canfarotta F, Thomson A, Czulak J, Johnson R, Crapnell R, Banks C, Payne B, Seyedin S, Losada-Perez P, Peeters M. Molecularly Imprinted Polymer Nanoparticles Enable Rapid, Reliable, and Robust Point-of-Care Thermal Detection of SARS-CoV-2. ACS Sensors 2022, 7(4), 1122-1131.
- Seumo Tchekwagep P, Crapnell D, Banks CE, Betlem K, Rinner U, Canfarotta F, Lowdon JW, Eersels K, van Grinsven B, Peeters M, McClements J. A Critical Review on the Use of Molecular Imprinting for Trace Heavy Metal and Micropollutant Detection. Chemosensors 2022, 10(8), 296.
- Saubade F, Pilkington L, Liauw C, Gomes L, McClements J, Peeters M, Mohtadi M, Mergulhão F, Whitehead K. Principal Component Analysis to Determine the Surface Properties That Influence the Self-Cleaning Action of Hydrophobic Plant Leaves. Langmuir 2021, 37(27), 8177–8189.
- McClements J, Seumo P, Vilalela Strapazon A, Canfarotta F, Thomson A, Czulak J, Johnson R, Novakovic K, Losada-Perez P, Zaman A, Spyridopoulos I, Crapnell R, Banks C, Peeters M. Immobilization of Molecularly Imprinted Polymer Nanoparticles onto Surfaces using Different Strategies: Evaluating the Influence of the Functionalised Interface on the Performance of a Thermal Assay for the Detection of Cardiac Biomarker Troponin I. ACS Applied Materials and Interfaces 2021, 13(24), 27868-27879.
- McClements J, Gomes L, Spall J, Saubade F, Akhidime D, Peeters M, Mergulhao F, Whitehead K. Celebrating the centenary in polymer science: drawing inspiration from nature to develop anti-fouling coatings. The development of biomimetic polymer surfaces and their effect on bacterial fouling. Pure and Applied Chemistry 2021.
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Book Chapter
- Dann A, Kaur S, Stoufer S, Kim M, Kaur I, Moore M, Peeters M, McClements J. Molecularly Imprinted Polymers for Detection of Chemical and Microbial Contaminants in Foods. In: Reference Module in Food Science. Elsevier, 2023.
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Conference Proceedings (inc. Abstracts)
- McClements J, Dann A, Kaur S, Stoufer S, Kim M, Moore M, Peeters M. Molecularly Imprinted Polymer Nanoparticles for Norovirus Detection. In: BioFutures Symposium 2023. 2023, Newcastle upon Tyne: Northumbria University.
- Kaur S, Singla P, McClements J, Moore M, Kaur I, Peeters M. Development and evaluation of low-cost, easily deployable molecularly imprinted polymer technologies for norovirus detection. In: 17th Pacific Polymer Conference (PPC17). 2022, Brisbane Convention Centre, Australia: PPC.
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Reviews
- Singla P, Garg S, McClements J, Jamieson O, Peeters M, Mahajan R. Advances in the therapeutic delivery and applications of functionalized Pluronics: A critical review. Advances in Colloid and Interface Science 2022, 299, 102563.