Clinical studies arising from the Imaging Programme and from collaborations with the Northern Institute for Cancer Research are performed at the Centre.

Members of the Centre are involved in developing pre-clinical contrast media for work on our small bore MRI system.

Oncology projects

Publications

• Chan K-S, Cheung SM, Senn N, Husain E, Masannat Y, Heys S, He J. Peri-tumoural spatial distribution of lipid composition and tubule formation in breast cancer. BMC Cancer 2022, 22(1), 285.

• Cheung SM, Husain E, Mallikourti V, Masannat Y, Heys S, He J. Intra-tumoural lipid composition and lymphovascular invasion in breast cancer via non-invasive magnetic resonance spectroscopy. European Radiology 2021, 31(6), 3703-3711.

• Cheung SM, Husain E, Masannat Y, Miller ID, Wahle K, Heys SD, He J. Lactate concentration in breast cancer using advanced magnetic resonance spectroscopy. British Journal of Cancer 2020, 123(2), 261-267.

• Mallikourti V, Cheung SM, Gagliardi T, Senn N, Masannat Y, McGoldrick T, Sharma R, Heys SD, He J. Phased-array combination of 2D MRS for lipid composition quantification in patients with breast cancer. Scientific Reports 2020, 10(1), 20041.

• Mallikourti V, Cheung SM, Gagliardi T, Masannat Y, Heys SD, He J. Optimal Phased-Array Signal Combination For Polyunsaturated Fatty Acids Measurement In Breast Cancer Using Multiple Quantum Coherence MR Spectroscopy At 3T. Scientific Reports 2019, 9(1), 9259.

• Senn N, Masannat Y, Husain E, Siow B, Heys SD, He J. Q-space imaging yields a higher effect gradient to assess cellularity than conventional diffusion-weighted imaging methods at 3.0 t: A pilot study with freshly excised whole-breast tumors. Radiology: Imaging Cancer 2019, 1(1), e190008.

• Zahra MA, Hollingsworth KG, Sala E, Lomas DJ, Tan LT. Dynamic contrast-enhanced MRI as a predictor of tumour response to radiotherapy. Lancet Oncology 2007; 8(1), 63-74.