Research Publications and
Conference Papers

Diabetes

• Sattar N, Taheri S, Astling DP, Chadwick J, Hinterberg MA, Holmes MV, Troth EV, Welsh P, Zaghloul H, Chagoury O, Lean M, Taylor R, Williams S. Prediction of cardiometabolic health through changes in plasma proteins with intentional weight loss in the DiRECT and DIADEM-I randomised clinical trials of type 2 diabetes remission. Diabetes Care 2023; Sep 26:dc230602.  doi: 10.2337/dc23-0602. Online ahead of print.
• Corbin LJ, Hughes DA, Bull CJ, Vincent EE, SmithML, McConnachie A, Messow C, Welsh P, Taylor R, Lean MEJ, Sattar N, Timpson NJ. The metabolomic signature of weight loss and remission in the Diabetes Remission Clinical Trial (DiRECT). Diabetologia 2023 Online
• Taylor  R, Barnes AC,  Hollingsworth KG, Irvine KM, Solovyova A, Clark. L, Martin-Ruiz C, Romeres R, Koulman A, Meek,CM, Jenkins B, Cobelli C, Holman R. Aetiology of Type 2 diabetes in people with a ‘normal’ body mass index: testing the personal fat threshold hypothesis. Clin Sci (Lond)(2023)137: 1333–1346 doi.org/10.1042/CS20230586

Cardiovascular

• Jesuthasan, A., S. Zhyzhneuskaya, C. Peters, A. C. Barnes, K. G. Hollingsworth, N. Sattar, M. E. J. Lean, R. Taylor, and A. H. Al-Mrabeh. "Sex Differences in Intraorgan Fat Levels and Hepatic Lipid Metabolism: Implications for Cardiovascular Health and Remission of Type 2 Diabetes after Dietary Weight Loss." [In eng]. Diabetologia 65, no. 1 (Jan 2022): 226-33.

Diabetes

• Jesuthasan, Aaron, Sviatlana Zhyzhneuskaya, Carl Peters, Alison C. Barnes, Kieren G. Hollingsworth, Naveed Sattar, Michael E. J. Lean, Roy Taylor, and Ahmad H. Al-Mrabeh. "Sex Differences in Intraorgan Fat Levels and Hepatic Lipid Metabolism: Implications for Cardiovascular Health and Remission of Type 2 Diabetes after Dietary Weight Loss." Diabetologia 65, no. 1 (2022/01/01 2022): 226-33. https://dx.doi.org/10.1007/s00125-021-05583-4.
• Rehackova L, Rodrigues AM, Thom G, Brosnahan N, Barnes AC, McCombie L, Leslie WS, Zhyzhneuskaya S, Peters C, Adamson AJ, Lean MEJ, Taylor R, Sniehotta FF. Delivering the Diabetes Remission Clinical Trial (DiRECT) in primary care: A mixed-methods study of experiences of health care. Diabet Med 2022 39:e14952;  DOI: 10.1111/dme.14752
• Williams SA, Rachel Ostroff, Michael A. Hinterberg, Josef Coresh, Christie M. Ballantyne, Matsushita K, Mueller CE, Walter J, Jonasson C, Holman RR, Shah SH, Sattar N, Taylor R, et al. A proteomic surrogate for cardiovascular outcomes that is sensitive to multiple mechanisms of change in risk. Science Translational Reports 2022, 14, eabj9625.
• Cassidy S, Trenell M, Stefanetti RJ, Charman SJ, Barnes AC, Brosnahan N, McCombie L, Thom G, Peters C, Zhyzhneuskaya S, Leslie WS, Catt C, Catt M, McConnachie A, Sattar N, Sniehotta FF, Lean MEJ, Taylor R. Physical activity, inactivity and sleep during the Diabetes Remission Clinical Trial (DiRECT). Diabetic Medicine 2022 40:e15010.  doi: 10.1111/dme.15010
• Unwin D, Delon C, Unwin J, Tobin S, Taylor R. What predicts drug-free type 2 diabetes remission? Insights from an 8-year general practice service evaluation of a lower carbohydrate diet with weight loss BMJ Nutrition, Prevention and Health 2022 0:e000544. Doi:10.1136/bmjnph-2022-000544
• Taylor R. Type 2 Diabetes: The Problem and the Solution. Br J Diabetes 2022;22(Supp1):S55-S58 https://bjd-abcd.com/index.php/bjd/article/view/1055/1307
• Riddle MC, Cefalu WT, Evans PH, Gerstein HC, Nauck MA, Oh WK, Rothberg AE, le Roux CW, Rubino F, Schauer P, Taylor R, Twenefour D Consensus Report: Definition and Interpretation of Remission in Type 2 Diabetes Diabetes Care 2021;44(10):2438–2444 https://doi.org/10.2337/dci21-0034

Muscle

• Reyngoudt, H., F. E. Smith, E. Caldas de Almeida Araújo, I. Wilson, R. Fernández-Torrón, M. K. James, U. R. Moore, J. Díaz-Manera, B. Marty, N. Azzabou, H. Gordish, L. Rufibach, T. Hodgson, D. Wallace, L. Ward, J. M. Boisserie, J. Le Louër, H. Hilsden, H. Sutherland, A. Canal, J. Y. Hogrel, M. Jacobs, T. Stojkovic, K. Bushby, A. Mayhew, V. Straub, P. G. Carlier, and A. M. Blamire. "Three-Year Quantitative Magnetic Resonance Imaging and Phosphorus Magnetic Resonance Spectroscopy Study in Lower Limb Muscle in Dysferlinopathy." J Cachexia Sarcopenia Muscle 13, no. 3 (Jun 2022): 1850-63. https://dx.doi.org/10.1002/jcsm.12987.
• Heskamp, L., A. R. Miller, M. G. Birkbeck, J. Hall, I. S. Schofield, A. M. Blamire, and R. G. Whittaker. "In Vivo 3d Imaging of Human Motor Units in Upper and Lower Limb Muscles." Clin Neurophysiol 141 (Sep 2022): 91-100. https://dx.doi.org/10.1016/j.clinph.2022.05.018.

Neuroscience

• Cousins, D. A., Barnes, T. R. E., Young, A. H., Delgado, O., & Paton, C. (2022). Plus ca change? Switching lithium preparations. BJPsych Bull, 1-6. 
• Jayakody, K., Gallagher, P., Lloyd, A. J., & Cousins, D. A. (2022). A quantitative analysis of the relationship between affective state and personality ratings in inpatient depression (RAPID). Psychol Med, 1-10. 

Oncology

• Chan K-S, Cheung SM, Senn N, Husain E, Masannat Y, Heys S, He J. Peri-tumoural spatial distribution of lipid composition and tubule formation in breast cancer. BMC Cancer 2022, 22(1), 285.

Cardiovascular

• Wibowo, P. G., S. J. Charman, N. C. Okwose, L. Velicki, D. Popovic, K. G. Hollingsworth, G. A. MacGowan, and D. G. Jakovljevic. "Association between Cardiac High-Energy Phosphate Metabolism and Whole Body Metabolism in Healthy Female Adults." [In eng]. Physiol Res  (May 12 2021).
• Gbinigie, H., L. Coats, J. D. Parikh, K. G. Hollingsworth, and L. Gan. "A 4d Flow Cardiovascular Magnetic Resonance Study of Flow Asymmetry and Haemodynamic Quantity Correlations in the Pulmonary Artery." [In eng]. Physiol Meas 42, no. 2 (Mar 11 2021): 025005.

Diabetes

• Leslie, Wilma S., Eman Ali, Leanne Harris, C. Martina Messow, Naomi T. Brosnahan, George Thom, E. Louise McCombie, Alison C. Barnes, Naveed Sattar, Roy Taylor, and Michael E. J. Lean. "Antihypertensive Medication Needs and Blood Pressure Control with Weight Loss in the Diabetes Remission Clinical Trial (Direct)." Diabetologia 64, no. 9 (2021/09/01 2021): 1927-38. https://dx.doi.org/10.1007/s00125-021-05471-x.
• Riddle, Matthew C., William T. Cefalu, Philip H. Evans, Hertzel C. Gerstein, Michael A. Nauck, William K. Oh, Amy E. Rothberg, Carel W. le Roux, Francesco Rubino, Philip Schauer, Roy Taylor, and Douglas Twenefour. "Consensus Report: Definition and Interpretation of Remission in Type 2 Diabetes." Diabetologia 64, no. 11 (2021/11/01 2021): 2359-66. https://dx.doi.org/10.1007/s00125-021-05542-z.
• Al-Mrabeh A, Peters C, Hollingsworth KG, Taylor R. Measurement of intraorgan fat and hepatic output of triglycerides in human type 2 diabetes by magnetic resonance and intralipid infusion techniques. Star Protocols 2021; 2:1 https://doi.org/10.1016/j.xpro.2021.100355
• Brosnahan N, Leslie W, McCombie L, Barnes A, Thom G, McConnachie A, Messow C M, Sattar N, Taylor R, Lean M E J.  Brief formula low-energy-diet for relapse management during weight loss maintenance in the Diabetes Remission Clinical Trial (DiRECT). J Hum Nutr Diet. 2021;00:1-8  https://doi.org/10.1111/jhn.12839
• Rehackova L, Rodrigues AM, Thom G, Brosnahan N, Barnes AC, McCombie L, Leslie WS, Zhyzhneuskaya S, Peters C, Adamson AJ, Lean MEJ, Taylor R, Sniehotta FF. Participant experiences in the Diabetes REmission Clinical Trial (DiRECT). Diabet Med 2021;00:e14689 https://doi.org/10.1111/dme.14689
• Leslie WS, Ali E, Harris L, Martina Messow C, Brosnahan NT, Thom G, McCombie EL, Barnes AC, Sattar N, Taylor R, Lean MEJ. Antihypertensive medication needs and blood pressure control with weight loss in the Diabetes REmission Clinical Trial (DiRECT). Diabetologia (2021) 64:1927–1938 https//doi.org/10.1007/s00125-021-05471-x
• Taylor R. Type 2 diabetes and remission: practical management guided by pathophysiology. Journal of Internal Medicine 2021; 289: 754–770 http://dx.doi.org/10.1111/joim.13214
• Taylor R, Ramachandran A, Yancy Jr WS, Forouhi NG. Nutritional basis of type 2 diabetes remission. Brit Med J 2021; 373: n1449.
•  Petrov M, Taylor R. Intra-pancreatic fat deposition: Piecing the exocrine and endocrine pancreas together.   Nature Reviews Gastroenterology & Hepatology 2021 online https://doi.org/10.1038/s41575-021-00551-0. [View only https://rdcu.be/cCQzO]

Muscle

• Birkbeck, M. G., A. M. Blamire, R. G. Whittaker, A. A. Sayer, and R. M. Dodds. "The Role of Novel Motor Unit Magnetic Resonance Imaging to Investigate Motor Unit Activity in Ageing Skeletal Muscle." J Cachexia Sarcopenia Muscle 12, no. 1 (Feb 2021): 17-29. https://dx.doi.org/10.1002/jcsm.12655 
• Heskamp, L., M. G. Birkbeck, R. G. Whittaker, I. S. Schofield, and A. M. Blamire. "The Muscle Twitch Profile Assessed with Motor Unit Magnetic Resonance Imaging." NMR Biomed 34, no. 3 (Mar 2021): e4466. https://dx.doi.org/10.1002/nbm.4466.

Neuroscience

• Bellivier, F., Young, A. H., Scott, J., Etain, B., Cousins, D. A., & Consortium, R. L. (2021). Make lithium great again - Precisely! Bipolar Disord, 23(2), 209-210.
• Necus, J., Smith, F. E., Thelwall, P. E., Flowers, C. J., Sinha, N., Taylor, P. N., Blamire, A. M., Wang, Y., & Cousins, D. A. (2021). Quantification of brain proton longitudinal relaxation (T1 ) in lithium-treated and lithium-naive patients with bipolar disorder in comparison to healthy controls. Bipolar Disord, 23(1), 41-48. 
• Lucini-Paioni, S., Squarcina, L., Cousins, D. A., & Brambilla, P. (2021). Lithium effects on Hippocampus volumes in patients with bipolar disorder. J Affect Disord, 294, 521-526. 
• McAllister-Williams, R. H., Bulmer, S., Newton, K., Heath, K., Cousins, D. A., & Currie, A. (2021). Assessment for vagus nerve stimulation in patients with difficult-to-treat depression: a model from the Newcastle Regional Affective Disorders Service (RADS). J Affect Disord, 280(Pt A), 315-318. 

Oncology

• Cheung SM, Husain E, Mallikourti V, Masannat Y, Heys S, He J. Intra-tumoural lipid composition and lymphovascular invasion in breast cancer via non-invasive magnetic resonance spectroscopy. European Radiology 2021, 31(6), 3703-3711.

Cardiovascular

• Steele, H., A. Gomez-Duran, A. Pyle, S. Hopton, J. Newman, R. J. Stefanetti, S. J. Charman, et al. "Metabolic Effects of Bezafibrate in Mitochondrial Disease." [In eng]. EMBO Mol Med 12, no. 3 (Mar 6 2020): e11589. https://doi.org/10.15252/emmm.201911589. https://www.ncbi.nlm.nih.gov/pubmed/32107855.
• Dewhurst, P., L. Coats, J. D. Parikh, K. G. Hollingsworth, and L. Gan. "The Role of Flow Rotation in the Adult Right Atrium: A 4d Flow Cardiovascular Magnetic Resonance Study." [In eng]. Physiol Meas 41, no. 3 (Apr 16 2020): 035007.
  
• Jabbar, A., L. Ingoe, S. Junejo, P. Carey, C. Addison, H. Thomas, J. D. Parikh, et al. "Effect of Levothyroxine on Left Ventricular Ejection Fraction in Patients with Subclinical Hypothyroidism and Acute Myocardial Infarction: A Randomized Clinical Trial." [In eng]. Jama 324, no. 3 (Jul 21 2020): 249-58. https://doi.org/10.1001/jama.2020.9389.

Diabetes

• Al-Mrabeh A, Hollingsworth KG. Shaw JAM, McConnachie A, Sattar N; Lean MEJ, Taylor R. 2-year remission of type 2 diabetes and pancreas morphology: a post-hoc analysis of the DiRECT open-label, cluster-randomised trial. Lancet Diabetes Endocrinol 2020; 8: 939-948; doi: 10.1016/S2213-8587(20)30303-X
• Yiqiao X, Davies A, Briggs A, McCombie L, Martina Messow C, Grieve E, Leslie WM, Taylor R, Lean MEJ. Type 2 diabetes remission: 2 year within-trial and lifetime-horizon cost-effectiveness of the Diabetes Remission Clinical Trial (DiRECT)/Counterweight-Plus weight management programme. Diabetologia 2020; DOI: 10.1007/s00125-020-05220-6; In press.
• Kusinski LC, Murphy HR, De Lucia Rolfe E, Rennie KL, Oude Griep LM, Hughes D, Taylor R, Meek CL. Dietary Intervention in pregnant women with gestational diabetes; protocol for the DiGest randomised controlled trial. Nutrients 2020; April 22; doi: 10.3390/nu12041165.
• Preshaw PM, Taylor JJ, Jaedicke KM, De Jager M, Bikker JW, Selten W, Bissett SM, Whall KM, Van de Merwe R, Areibi A, Jitprasertwong P, Al-Shahwani R, Weaver J, Taylor R, Wassall RR. Treatment of periodontitis reduces systemic inflammation in type 2 diabetes. Journal of Clinical Periodontology 2020; February 27; doi: 10.111/jcpe.13274.
• Zhyzhneuskaya SV, Al-Mrabeh A, Peters C, Barnes AC, Aribasala B, Hollingsworth KG, McConnachie A, Sattar N, Lean MEJ, Taylor R. Time course of normalisation of functional beta cell capacity in DiRECT after weight loss in type 2 diabetes. Diabetes Care 2020; April; doi: 10.2337/dc19-0371.
• Al-Mrabeh A, Zhyzhneuskaya SV, Peters C, Barnes AC, Melhem S, Jesuthasan A, Aribisala B, Hollingsworth KG, Lietz G, Mather JC, Sattar N, Lean MEJ, Taylor R. Hepatic Lipoprotein Export and Remission of Human Type 2 Diabetes after Weight Loss. Cell Metabolism 2020 Feb 4;31(2):233-249.e4. doi: 10.1016/j.cmet.2019.11.018.
• Thom G, McIntosh A, Messow C-M, Leslie WS, Barnes A, Brosnahan N, McCombie L, Malkova D, Al-Mrabeh A, Zhyzhneuskaya S, Welsh P, Sattar N, Taylor R, Lean MEJ. Weight loss-induced increase in fasting ghrelin concentration is a predictor of weight regain: Evidence from the Diabetes Remission Clinical Trial (DiRECT). Diabetes Obes Metab 2020; Dec 2;DOI: 10.1111/dom.14274
• Thom G, Messow C‐M, Leslie WS,  Barnes AC,  Brosnahan N,  McCombie EL,  Al‐Mrabeh A,  Zhyzhneuskaya S,  Welsh P,  Sattar N, Taylor R, Lean MEJ. Predictors of type 2 diabetes remission in the Diabetes Remission Clinical Trial (DiRECT).  Diabetic Medicine  2020 https://doi.org/10.1111/dme.14395
• Shaden M, Steven S, Taylor R, Al-Mrabeh A. Effect of Weight Loss by Low-Calorie Diet on Cardiovascular Health in Type 2 Diabetes: An Interventional Cohort Study. Nutrients 2021, 13(5), 1465 doi: 10.3390/nu13051465
• Taylor R. Remission of type 2 diabetes – Latest Information for Health care Professionals. Practical Diabetes 2020 37:177-182

Muscle

• Birkbeck, M. G., L. Heskamp, I. S. Schofield, A. M. Blamire, and R. G. Whittaker. "Non-Invasive Imaging of Single Human Motor Units." Clin Neurophysiol 131, no. 6 (Jun 2020): 1399-406. https://dx.doi.org/10.1016/j.clinph.2020.02.004.
• Porcari, P., M. G. Hall, C. A. Clark, E. Greally, V. Straub, and A. M. Blamire. "Time-Dependent Diffusion Mri as a Probe of Microstructural Changes in a Mouse Model of Duchenne Muscular Dystrophy." NMR Biomed 33, no. 5 (May 2020): e4276. https://dx.doi.org/10.1002/nbm.4276.

Neuroscience

• Cousins, D. A., Squarcina, L., Boumezbeur, F., Young, A. H., & Bellivier, F. (2020). Lithium: past, present, and future. Lancet Psychiatry, 7(3), 222-224.

Oncology

• Cheung SM, Husain E, Masannat Y, Miller ID, Wahle K, Heys SD, He J. Lactate concentration in breast cancer using advanced magnetic resonance spectroscopy. British Journal of Cancer 2020, 123(2), 261-267.
• Mallikourti V, Cheung SM, Gagliardi T, Senn N, Masannat Y, McGoldrick T, Sharma R, Heys SD, He J. Phased-array combination of 2D MRS for lipid composition quantification in patients with breast cancer. Scientific Reports 2020, 10(1), 20041.

Cardiovascular

• Houghton, D., P. Zalewski, K. Hallsworth, S. Cassidy, C. Thoma, L. Avery, J. Slomko, et al. "The Degree of Hepatic Steatosis Associates with Impaired Cardiac and Autonomic Function." [In eng]. J Hepatol 70, no. 6 (Jun 2019): 1203-13. https://doi.org/10.1016/j.jhep.2019.01.035. https://www.ncbi.nlm.nih.gov/pubmed/30769007.

Diabetes

• Rehackova L, Araujo-Soares V, Steven S, Adamson AJ, Taylor R, Sniehotta FF. Behaviour change during dietary type 2 diabetes remission: A longitudinal qualitative evaluation of an intervention using a very low energy diet. Diabetic Med 2020 June;37(6):953-962. doi: 10.1111/dme.14066. Epub 2019 Aug 8.
• Xin Y, Davies A, McCombie L, Briggs A, Messow, C-M, Grieve E, Leslie WS, Taylor R, Lean MEJ.  Type 2 diabetes remission: economic evaluation of the DiRECT/Counterweight-Plus weight management programme within a primary care randomized controlled trial.  Diabetic Med 2019.  April 26 doi:10.1111/dme.13981.
• Lean MEJ, Leslie WS, Barnes AC, Brosnahan N, Thom G, McCombie L, Peters C, Zhyzhneuskaya S, Al-Mrabeh A, Hollingsworth KG, Rodrigues AM, Rehackova L, Adamson AJ, Sniehotta FF, Mathers JM, Ross HM, McIlvenna Y, Welsh, P, Kean, S, Ford I, McConnachie A, Messow, C-M Sattar N, Taylor R.  Durability of a primary care-led weight-management intervention for remission of type 2 diabetes: 2-year results of the DiRECT open-label, cluster-randomised trial.  Lancet 2019; 7: 344–55; doi:10.1016/s2213-8587(19)30068-3.
• Taylor R, Al-Mrabeh A, Sattar N.  Understanding the mechanisms of reversal of type 2 diabetes. Lancet Diabetes and Endocrinol. 2019; 7:726-736. doi: 10.1016/S2213-8587(19)30076-2

Muscle

• Whittaker, R. G., P. Porcari, L. Braz, T. L. Williams, I. S. Schofield, and A. M. Blamire. "Functional Magnetic Resonance Imaging of Human Motor Unit Fasciculation in Amyotrophic Lateral Sclerosis." Ann Neurol 85, no. 3 (Mar 2019): 455-59. https://dx.doi.org/10.1002/ana.25422.

Neuroscience

• Necus, J., Sinha, N., Smith, F. E., Thelwall, P. E., Flowers, C. J., Taylor, P. N., Blamire, A. M., Cousins, D. A., & Wang, Y. (2019). White matter microstructural properties in bipolar disorder in relationship to the spatial distribution of lithium in the brain. J Affect Disord, 253, 224-231. 
• Scott, J., Hidalgo-Mazzei, D., Strawbridge, R., Young, A., Resche-Rigon, M., Etain, B., Andreassen, O. A., Bauer, M., Bennabi, D., Blamire, A. M., Boumezbeur, F., Brambilla, P., Cattane, N., Cattaneo, A., Chupin, M., Coello, K., Cointepas, Y., Colom, F., Cousins, D. A., . . . Bellivier, F. (2019). Prospective cohort study of early biosignatures of response to lithium in bipolar-I-disorders: overview of the H2020-funded R-LiNK initiative. Int J Bipolar Disord, 7(1), 20.

Oncology

• Mallikourti V, Cheung SM, Gagliardi T, Masannat Y, Heys SD, He J. Optimal Phased-Array Signal Combination For Polyunsaturated Fatty Acids Measurement In Breast Cancer Using Multiple Quantum Coherence MR Spectroscopy At 3T. Scientific Reports 2019, 9(1), 9259.
• Senn N, Masannat Y, Husain E, Siow B, Heys SD, He J. Q-space imaging yields a higher effect gradient to assess cellularity than conventional diffusion-weighted imaging methods at 3.0 t: A pilot study with freshly excised whole-breast tumors. Radiology: Imaging Cancer 2019, 1(1), e190008.

Cardiovascular

• Parikh, J. D., K. G. Hollingsworth, D. Wallace, A. M. Blamire, and G. A. MacGowan. "Left Ventricular Functional, Structural and Energetic Effects of Normal Aging: Comparison with Hypertension." [In eng]. PLoS One 12, no. 5 (2017): e0177404.

Dementia

• Firbank MJ, O'Brien JT, Taylor JP. Long reaction times are associated with delayed brain activity in Lewy body dementia. Hum Brain Mapp 2018;39(2):633-643. doi: 10.1002/hbm.23866.
• Minett T, Su L, Mak E, Williams G, Firbank M, Lawson RA, Yarnall AJ, Duncan GW, Owen AM, Khoo TK, Brooks DJ, Rowe JB, Barker RA, Burn D, O'Brien JT.  Longitudinal diffusion tensor imaging changes in early Parkinson's disease: ICICLE-PD study. J Neurol. 2018. doi: 10.1007/s00415-018-8873-0.
• Donaghy PC, Firbank MJ, Thomas AJ, Lloyd J, Petrides G, Barnett N, Olsen K, O'Brien JT. Clinical and imaging correlates of amyloid deposition in dementia with Lewy bodies. Mov Disord 2018. doi: 10.1002/mds.27403.
• Schumacher J, Peraza LR, Firbank M, Thomas AJ, Kaiser M, Gallagher P, O'Brien JT, Blamire AM, Taylor JP. Functional connectivity in dementia with Lewy bodies: a within- and between-network analysis. Hum Brain Mapp 2018;39(3):1118-1129. doi: 10.1002/hbm.23901.
• Firbank MJ, Parikh J, Murphy N, Killen A, Allan CL, Collerton D, Blamire AM, Taylor JP. Reduced occipital GABA in Parkinson disease with visual hallucinations. Neurology 2018 (In press).

Diabetes

• Taylor R, Al-Mrabeh A, Zhyzhneuskaya S, Peters C, Barnes A, Aribisala B, Hollingsworth KG, Mathers JC, Sattar N, Lean MEJ. Remission of human type 2 diabetes requires decrease in liver and pancreas fat content but is dependent upon capacity for beta cell recovery. Cell Metab. 2018 Oct 2;28(4):547-556.e3. doi: 10.1016/j.cmet.2018.07.003.
• Taylor R, Barnes AC.  Translating aetiological insight into sustainable management into type 2 diabetes. Diabetologia 2018: 61 273-283 doi: 10.1007/s00125-017-4504.

Muscle

• Porcari, P., M. G. Hall, C. A. Clark, E. Greally, V. Straub, and A. M. Blamire. "The Effects of Ageing on Mouse Muscle Microstructure: A Comparative Study of Time-Dependent Diffusion Mri and Histological Assessment." NMR Biomed 31, no. 3 (Mar 2018). https://dx.doi.org/10.1002/nbm.3881.
• Díaz-Manera, Jordi, Roberto Fernandez-Torron, Jaume Llauger, Meredith James, Anna Mayhew, Fiona Elizabeth Smith, Ursula Moore, Andrew Blamire, Pierre Carlier, Laura Rufibach, Plavi Mittal, Michelle Eagle, Marni Jacobs, Tim Hodgson, Dorothy Wallace, Louise Ward, Mark Smith, Roberto Stramare, Alessandro Rampado, and Volker Straub. "Muscle Mri in Patients with Dysferlinopathy: Pattern Recognition and Implications for Clinical Trials." Journal of neurology, neurosurgery, and psychiatry 89 (05/07 2018). https://dx.doi.org/10.1136/jnnp-2017-317488.

Neuroscience

• Jeppesen, J., Otto, M., Frederiksen, Y., Hansen, A. K., Fedorova, T. D., Knudsen, K., Nahimi, A., Brooks, D. J., Borghammer, P., & Sommerauer, M. (2018). Observations on muscle activity in REM sleep behavior disorder assessed with a semi-automated scoring algorithm. Clin Neurophysiol, 129(3), 541-547. 
• Martin, D., Hurlbert, A., & Cousins, D. A. (2018). Sleep Disturbance and the Change from White to Red Lighting at Night on Old Age Psychiatry Wards: A Quality Improvement Project. Arch Psychiatr Nurs, 32(3), 379-383. 
• Reinbold, C. S., Forstner, A. J., Hecker, J., Fullerton, J. M., Hoffmann, P., Hou, L., Heilbronner, U., Degenhardt, F., Adli, M., Akiyama, K., Akula, N., Ardau, R., Arias, B., Backlund, L., Benabarre, A., Bengesser, S., Bhattacharjee, A. K., Biernacka, J. M., Birner, A., . . . Cichon, S. (2018). Analysis of the Influence of microRNAs in Lithium Response in Bipolar Disorder. Front Psychiatry, 9, 207. 
• Smart, C., McAllister-Williams, H., & Cousins, D. A. (2018). Acetylcholinesterase inhibitors in treatment-resistant psychotic depression. Ther Adv Psychopharmacol, 8(1), 59-61. 
• Smith, F. E., Thelwall, P. E., Necus, J., Flowers, C. J., Blamire, A. M., & Cousins, D. A. (2018). 3D (7)Li magnetic resonance imaging of brain lithium distribution in bipolar disorder. Mol Psychiatry, 23(11), 2184-2191. 

Cardiovascular

• Parikh JD, Kakarla J, Keavney B, O'Sullivan JJ, Ford GA, Blamire AM, Hollingsworth KG, Coats L. 4D flow MRI assessment of right atrial flow patterns in the normal heart - influence of caval vein arrangement and implications for the patent foramen ovale. PLoS One. 2017 Mar 10;12(3):e0173046. doi: 10.1371/journal.pone.0173046. eCollection 2017. 
• MacGowan GA, Parikh JD, Hollingsworth KG. Diffusion Tensor Magnetic Resonance Imaging of the Heart: Looking Into the Layers of the Myocardium.  J Am Coll Cardiol. 2017 Feb 14;69(6):677-678. doi: 10.1016/j.jacc.2016.10.080.
• Parikh, J. D., K. G. Hollingsworth, D. Wallace, A. M. Blamire, and G. A. MacGowan. "Left Ventricular Functional, Structural and Energetic Effects of Normal Aging: Comparison with Hypertension." [In eng]. PLoS One 12, no. 5 (2017): e0177404. https://doi.org/10.1371/journal.pone.0177404. https://www.ncbi.nlm.nih.gov/pubmed/28493996.

Dementia

• Kobeleva X, Firbank M, Peraza L, Gallagher P, Thomas A, Burn DJ, O’Brien J, Taylor JP. Divergent functional connectivity during attentional processing in Lewy body dementia and Alzheimer's disease. Cortex 2017. doi: 10.1016/j.cortex.2017.02.016.
• Mak E, Su L, Williams GB, Firbank MJ, Lawson RA, Yarnall AJ, Duncan GW, Mollenhauer B, Longitudinal whole-brain atrophy and ventricular enlargement in nondemented Parkinson's disease Neurobiol Aging. 2017; 55:78-90. doi: 10.1016/j.neurobiolaging.2017.03.012.

Diabetes

• Lean MEJ, Leslie WS, Barnes AC, Brosnahan N, Thom G, McCombie L, Peters C, Zhyzhneuskaya S, Al-Mrabeh A, Hollingsworth KG, Rodrigues AM, Rehackova L, Adamson AJ, Sniehotta FF, Mathers JM, Ross HM, McIlvenna Y, Stefanetti R, Trenell M, Welsh P, Kean S, Ford I, McConnachie A, Sattar N, Taylor R. Primary care weight-management for type 2 diabetes: the cluster-randomised Diabetes Remission Clinical Trial (DiRECT). Lancet 2017; 391:541-51 doi.org/10.1016/S0140-6736(17)33102-1 (IF 44)
• Taylor R, Leslie WS, Barnes AC, Brosnahan N, Thom G, McCombie L, Peters C, Zhyzhneuskaya S, Al-Mrabeh A, Hollingsworth KG, Rodrigues AM, Rehackova L, Adamson2 AJ, Sniehotta FF, Mathers JM, Ross HM, McIlvenna Y, Stefanetti R, Trenell M, Welsh P, Kean S, Ford I, McConnachie A, Sattar N, Lean MEJ. Clinical and metabolic features of the randomised controlled Diabetes Remission Clinical Trial (DiRECT) cohort. Diabetologia 2017; 61:589-98 https://doi.org/10.1007/s00125-017-4503-0 (IF 6.2)
• Rehackova L, Araujo-Soares V, Adamson AJ, Steven S, Taylor R, Sniehotta F. F. Acceptability of a very-low-energy diet in Type 2 diabetes: patient experiences and behaviour regulation Diabetic Med 2017; 34: 1554–1567
• Al-Mrabeh A, Hollingsworth KG, Steven S, Tiniakos D and Taylor R. Quantification of intrapancreatic fat in type 2 diabetes by MRI. PLOS One. April 3, 2017https://doi.org/10.1371/journal.pone.0174660.
• Hodson K, Dalla Man C, Smith FE, Barnes A, McParlin C, Cobelli C, Robson SC, Araujo-Soares V, Taylor R. Liver triacylglycerol content and gestational diabetes: Effects of moderate calorie restriction. Diabetologia. 2017 Feb;60(2):306-313. doi: 10.1007/s00125-016-4143-9. PMID: 27817155. 
• Leslie WS, Taylor R, Harris L, Lean M. Weight losses with low energy formula diets in obese patients with and without type 2 diabetes: Systematic review and meta-analysis. Int J Obes (Lond). 2017; 41:96-101. doi: 10.1038/ijo.2016.175.

Physics 

• Mann LW, Higgins DM, Peters CN, Cassidy S, Hodson KK, Coombs A, Taylor R, Hollingsworth KG. Accelerating MR Imaging Liver Steatosis Measurement Using Combined Compressed Sensing and Parallel Imaging: A Quantitative Evaluation. Radiology. 2016 Jan;278(1):247-56. doi: 10.1148/radiol.2015150320. Epub 2015 Jul 28.

Cardiovascular

• Parikh JD, Hollingsworth KG, Wallace D, Blamire AM, MacGowan GA. Normal age-related changes in left ventricular function: Role of afterload and subendocardial dysfunction. Int J Cardiol. 2016 Nov 15;223:306-312. doi: 10.1016/j.ijcard.2016.07.252. Epub 2016 Jul 30.
• Perkins RE, Hollingsworth KG, Eggett C, MacGowan GA, Bates MG, Trenell MI, Jakovljevic DG. Relationship between bioreactance and magnetic resonance imaging stroke volumes. Br J Anaesth. 2016 Jul;117(1):134-6. doi: 10.1093/bja/aew164.
• Parikh JD, Hollingsworth KG, Kunadian V, Blamire AM, MacGowan GA, Measurement of pulse wave velocity in normal ageing: comparison of Vicorder and magnetic resonance phase contrast imaging. BMC Cardiovascular Disorders, 2016 Feb 19;16(1):50. doi: 10.1186/s12872-016-0224-4.
• Cassidy S, Thoma C, Hallsworth K, Parikh JD, Hollingsworth KG, Taylor R, Jakovljevic DG, Trenell MI. High intensity intermittent exercise improves cardiac structure and function and reduces liver fat in patients with type 2 diabetes: a randomised controlled trial. Diabetologia. 2016 Jan;59(1):56-66. doi: 10.1007/s00125-015-3741-2. Epub 2015 Sep 9. 

Dementia

• Chen AQ, Akinyemi RO, Hase Y, Firbank MJ, Ndung'u MN, Foster V, Craggs LJL, Washida K, Okamoto Y, Thomas AJ, Polvikoski TM, Allan LM, Oakley AE, O'Brien JT, Horsburgh K, Ihara M, Kalaria RN. Frontal white matter hyperintensities, clasmatodendrosis and gliovascular abnormalities in ageing and post-stroke dementia. Brain 2016;139:242-258. doi: 10.1093/brain/awv328 PMID: 26667280.
• Firbank MJ, Watson R, Mak E, Aribisala B, Barber R, Colloby SJ, He JB, Blamire AM, O'Brien JT. Longitudinal diffusion tensor imaging in dementia with Lewy bodies and Alzheimer's disease. Parkinsonism Relat Disord. 2016;24:76-80. doi: 10.1016/j.parkreldis.2016.01.003 PMID: 26792342.
• Firbank M, Kobeleva X, Cherry G, Killen A, Gallagher P, Burn DJ, Thomas AJ, O'Brien JT, Taylor JP. Neural correlates of attention-executive dysfunction in lewy body dementia and Alzheimer's disease. Hum Brain Mapp. 2016;37(3):1254-1270. doi: 10.1002/hbm.23100 PMID: 26705763.
• Mak E, Su L, Williams GB, Watson R, Firbank M, Blamire A, O'Brien J. Differential Atrophy of Hippocampal Subfields: A Comparative Study of Dementia with Lewy Bodies and Alzheimer Disease. Am J Geriatr Psychiatry 2016;24(2):136-143. doi: 10.1016/j.jagp.2015.06.006 PMID: 26324541.
• Su L, Blamire AM, Watson R, He J, Aribisala B, O’Brien J. Cortical and subcortical changes in Alzheimer’s disease: a longitudinal and quantitative MRI study. Current Alz Res. 2016 2016;13(5):534-44 doi: 10.2174/1567205013666151116141416 PMID: 26567737.

Diabetes

• White MG, Shaw JAM, Taylor R. Type 2 diabetes: The pathologic basis of reversible beta-cell dysfunction. Diabetes Care 2016; 39:2080-88. doi 10.2337/dc16-0619. 
• Steven S, Hollingsworth KG, Small PK, Woodcock SA, Pucci A, Aribisala B, Al-Mrabeh A, Batterham RL, Taylor R. Calorie restriction and not glucagon-like peptide-1 explains the acute improvement in glucose control after gastric bypass in Type 2 diabetes. Diabet Med. 2016 Dec;33(12):1723-1731. doi: 10.1111/dme.13257. Epub 2016 Oct 8.
• Al-Mrabeh A, Hollingsworth KG, Steven S, Taylor R. Morphology of the pancreas in type 2 diabetes: effect of weight loss with or without normalisation of insulin secretory capacity. Diabetologia. 2016 Aug;59(8):1753-9. doi: 10.1007/s00125-016-3984-6. [Epub 2016 May 14].
• Avery  L, Charman  S, Taylor  L, Flynn  D, Mosely  K, Speight  J, Lievesley M, Taylor  R, Sniehotta  F, Trenell  M. Systematic development of a theory-informed multifaceted behavioural intervention to increase physical activity of adults with type 2 diabetes in routine primary care: Movement as Medicine for Type 2 Diabetes. Implementation Science. 2016 Jul 19;11:99. doi: 10.1186/s13012-016-0459-6.
• Steven S, Hollingsworth KG, Al-Mrabeh A, Avery L, Aribisal B, Caslake M and Taylor R. Very-Low-Calorie Diet and 6 Months of Weight Stability in Type 2 Diabetes: Pathophysiologic Changes in Responders and Nonresponders. Diabetes Care. 2016 May;39(5):808-15. doi: 10.2337/dc15-1942. Epub 2016 Mar 21. PMID: 27002059.
• Steven S, Hollingsworth KG, Small PK, Woodcock SA, Pucci A, Aribisala B, Al-Mrabeh A, Daly AK, Batterham RL, Taylor R. Weight Loss Decreases Excess Pancreatic Triacylglycerol Specifically in Type 2 Diabetes. Diabetes Care. 2016 Jan;39(1):158-65. doi: 10.2337/dc15-0750. Epub 2015 Dec 1. PMID: 26628414.
• Steven S, Hollingsworth KG, Small PK, Woodcock SA, Pucci A, Aribasala A, Al-Mrabeh A, Batterham RL and Taylor R. Increased GLP-1 at 7 days following RYGB does not translate into improved insulin secretion rates or glucose control compared to 7 days of VLCD.
• Wilma Leslie; Ian Ford; Naveed Sattar; Kieren Hollingsworth; Ashley Adamson; Falko Sniehotta; Louise McCombie; Naomi Brosnahan; Hazel Ross; John Mathers; Carl Peters; George Thom; Alison Barnes; Sharon Kean; Yvonne McIlvenna; Angela Rodrigues; Lucia Rehackova; Sviatlana Zhyzhneuskaya; Roy Taylor; Mike Lean. The Diabetes Remission Clinical Trial (DiRECT): protocol for a cluster randomised trial. BMC Family Practice. 2016 Feb 16;17:20. doi:10.1186/s12875-016-0406-2. PMID: 26879684.
• Cassidy S, Thoma C, Hallsworth K, Parikh J, Hollingsworth KG, Taylor R, Jakovljevic DG, Trenell MI. High intensity intermittent exercise improves cardiac structure and function and reduces liver fat in patients with type 2 diabetes: a randomised controlled trial. Diabetologia. 2016 Jan;59(1):56-66. doi: 10.1007/s00125-015-3741-2. Epub 2015 Sep 9.

Liver

• Fuchs CJ, Gonzalez JT, Beelen M, Cermak NM, Smith FE, Thelwall PE, Taylor R, Stevenson EJ, Trenell MI, van Loon LJ. Sucrose ingestion accelerates post-exercise liver, but not muscle glycogen repletion when compared to glucose ingestion. Med Sci Sports Exerc 2016 May;48(5 Suppl 1):820. doi: 10.1249/01.mss.0000487459.00030.d4. PMID: 27361493.
• Fuchs CJ, Gonzalez JT, Beelen M, Cermak NM, Smith FE, Thelwall PE, Taylor R, Trenell MI, Stevenson EJ, van Loon LJ. Sucrose ingestion after exhaustive exercise accelerates liver, but not muscle glycogen repletion compared with glucose ingestion in trained athletes. J Appl Physiol 2016 Jun 1;120(11):1328-34. doi: 10.1152/japplphysiol.01023.2015. Epub 2016 Mar 24. PMID: 27013608.
• Houghton D, Thoma C, Hallsworth K, Cassidy S, Hardy T, Burt AD, Tiniakos D, Hollingsworth KG, Taylor R, Day CP, McPherson S, Anstee QM, Trenell MI. Exercise Reduces Liver Lipids and Visceral Adiposity in Patients with Non-alcoholic Steatohepatitis in a Randomized Controlled Trial. Clin Gastroenterol Hepatol 2017 Jan;15(1):96-102.e3. doi: 10.1016/j.cgh.2016.07.031. Epub 2016 Aug 10. PMID: 27521509.

Neuroscience

• Hou, L., Heilbronner, U., Degenhardt, F., Adli, M., Akiyama, K., Akula, N., Ardau, R., Arias, B., Backlund, L., Banzato, C. E. M., Benabarre, A., Bengesser, S., Bhattacharjee, A. K., Biernacka, J. M., Birner, A., Brichant-Petitjean, C., Bui, E. T., Cervantes, P., Chen, G. B., . . . Schulze, T. G. (2016). Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study. Lancet, 387(10023), 1085-1093. 

Physics 

• Hollingsworth KG. Reducing acquisition time in clinical MRI by data undersampling and compressed sensing reconstruction. Phys Med Biol. 2015 Nov 7;60(21):R297-322. doi: 10.1088/0031-9155/60/21/R297. Epub 2015 Oct 8.
• Loughran T, Higgins DM, McCallum M, Coombs A, Straub V, Hollingsworth KG. Improving highly accelerated fat fraction measurements for clinical trials in muscular dystrophy: origin and quantitative effect of R2* changes. Radiology. 2015 May;275(2):570-8. doi: 10.1148/radiol.14141191. Epub 2015 Jan 7.

Brain Injury

• Blamire AM. Studying Stroke and Cerebral Ischemia by 1H MRS. eMagRes, 2015, Vol 4: 489–496. DOI 10.1002/9780470034590.emrstm1464.

Cardiovascular

• Jakovljevic DG, Papakonstantinou L, Blamire AM, MacGowan GA, Taylor R, Hollingsworth KG, Trenell MI. Effect of Physical Activity on Age-Related Changes in Cardiac Function and Performance in Women. Circ Cardiovasc Imaging 2015 doi:10.1161/CIRCIMAGING.114.002086.
• Madathil A, Hollingsworth KG, Blamire AM, Razvi S, Newton JL, Taylor R, Weaver JU. Levothyroxine improves abnormal cardiac bioenergetics in subclinical hypothyroidism: a cardiac magnetic resonance spectroscopic study. J Clin Endocrinol Metab. 2015 Apr;100(4):E607-10. doi: 10.1210/jc.2014-2942. Epub 2014 Dec 26. PMID: 25541742.
• Hallsworth K, Thoma C, Hollingsworth KG, Cassidy S, Anstee Q M, Day C P, Trenell M I. Modified high-intensity interval training reduces liver fat and improves cardiac function in non-alcoholic fatty liver disease: A randomised controlled trial. Clin Sci (Lond). 2015 Dec;129(12):1097-105. doi: 10.1042/CS20150308. Epub 2015 Aug 11.
• Cassidy S, Hallsworth K, Thoma C, MacGowan GA, Hollingsworth KG, Day CP, Taylor R, Jakovljevic DG, Trenell MI. Cardiac structure and function are altered in Type 2 diabetes and Non-alcoholic fatty liver disease and associate with glycemic control. Cardiovasc Diabetol. 2015 Feb 13;14:23. doi: 10.1186/s12933-015-0187-2.

Dementia

• Peraza LR, Taylor JP, Kaiser M. Divergent brain functional network alterations in dementia with Lewy bodies and Alzheimer's disease. Neurobiol Aging 2015;36(9):2458-2467. doi: 10.1016/j.neurobiolaging.2015.05.015 PMID: 26115566.
• Peraza LR, Colloby SJ, Firbank MJ, Greasy GS, McKeith IG, Kaiser M, O'Brien J, Taylor JP. Resting state in Parkinson's disease dementia and dementia with Lewy bodies: commonalities and differences. Int J Geriatr Psychiatry 2015;30(11):1135-1146. doi: 10.1002/gps.4342 PMID: 26270627.
• McAleese KE, Firbank M, Dey M, Colloby SJ, Walker L, Johnson M, Beverley JR, Taylor JP, Thomas AJ, O'Brien JT, Attems J. Cortical tau load is associated with white matter hyperintensities. Acta Neuropathol Commun. 2015;3. doi: 10.1186/s40478-015-0240-0 PMID: 26419828.
• Blanc F, Colloby SJ, Philippi N, de Petigny X, Jung B, Demuynck C, Phillipps C, Anthony P, Thomas A, Bing F, Lamy J, Martin-Hunyadi C, O'Brien JT, Cretin B, McKeith I, Armspach JP, Taylor JP. Cortical Thickness in Dementia with Lewy Bodies and Alzheimer's Disease: A Comparison of Prodromal and Dementia Stages. Plos One 2015;10(6). doi: 10.1371/journal.pone.0127396 PMID: 26061655.
• Mak E, Su L, Williams GB, Watson R, Firbank M, Blamire AM, O’Brien JT. Whole brain atrophy rates differentiate Alzheimer’s disease from dementia with Lewy bodies. In Press Neuroimage:Clinical (2015).
• Su L, Blamire AM, Watson R, He J, Aribisala B, O’Brien J. Cortical and subcortical changes in Alzheimer’s disease: a longitudinal and quantitative MRI study. In press, Current Alz Res. (2015).
• Mak E, Su L, Williams GB, Watson R, Firbank MJ, Blamire AM, O'Brien JT. Progressive cortical thinning and subcortical atrophy in dementia with Lewy bodies and Alzheimer's disease. Neurobiol Aging. 2015 Apr;36(4):1743-50. doi: 10.1016/j.neurobiolaging.2014.12.038. Epub 2015 Jan 8. PMID: 25649023.
• Watson R, Colloby SJ, Blamire AM, O'Brien JT. Assessment of regional gray matter loss in dementia with Lewy bodies: a surface-based MRI analysis. Am J Geriatr Psychiatry. 2015 Jan;23(1):38-46. doi: 10.1016/j.jagp.2014.07.005. Epub 2014 Jul 23. PMID: 25218360.
• Su L, Blamire AM, Watson R, He J, Aribisala B, O'Brien JT. Tissue microstructural changes in dementia with Lewy bodies revealed by quantitative MRI. J Neurol. 2015 Jan;262(1):165-72. doi: 10.1007/s00415-014-7541-2. Epub 2014 Oct 30. PMID: 25355453.

Diabetes

• Steven S, Taylor R. Restoring normoglycaemia by use of a very low calorie diet in long- and short-duration Type 2 diabetes. Diabet Med. 2015 Feb 12. doi: 10.1111/dme.12722. [Epub ahead of print]. PMID: 25683066.
• Macauley M, Hollingsworth KG, Smith FE, Thelwall PE, Al-Mrabeh A, Schweizer A, Foley JE, Taylor R. Effect of Vildagliptin on Hepatic Steatosis. J Clin Endocrinol Metab. 2015 Feb 12. doi: 10.1111/dme.12722. PMID: 25683066.
• Macauley M, Percival K, Thelwall PE, Hollingsworth KG, Taylor R. Altered volume, morphology and composition of the pancreas in type 2 diabetes. PLOS ONE. 2015. In Press.
• Steven S, Carey PE, Small PK, Taylor R. Reversal of Type 2 diabetes after bariatric surgery is determined by the degree of achieved weight loss in both short- and long-duration diabetes. Diabetic Medicine. 2015 Jan; 32(1):47-53. doi: 10.1111/dme.12567. Epub 2014 Sep 12. PMID: 25132043.
• Macauley M, Smith FE, Thelwall P, Taylor R. Diurnal variation in skeletal muscle and liver glycogen in humans with normal health and type 2 diabetes. Clinical Science. 2015 Jan 13. PMID: 25583442. In Press.
• Talks J, Manjunath V, Steel DHW, Peto T, Taylor R. New vessels detected on wide field imaging compared to 2-field and 7-field imaging: implications for diabetic retinopathy screening image analysis. Br J Ophthalmol 2015 doi:10.1136/bjophthalmol-2015-306719.
• Cassidy S, Hallsworth K, Thoma C, MacGowan GA, Hollingsworth KG, Day CP, Taylor R, Jakovljevic DG, Trenell MI. Cardiac structure and function are altered in Type 2 diabetes and Non-alcoholic fatty liver disease and associate with glycemic control. Cardiovasc Diabetol. 2015 Feb 13;14:23. doi: 10.1186/s12933-015-0187-2.

Liver

• Gonzalez J, Fuchs C, Smith F, Thelwall P, Taylor R, Stevenson E, Trenell M, Cermak N, and van Loon L. Ingestion of Glucose or Sucrose Prevents Liver but not Muscle Glycogen Depletion During Prolonged Endurance-type Exercise in Trained Cyclists. Am J Physiol Endocrinol Metab 2015 Oct 20. doi:10.1152/ajpendo.00376.2015. PMID: 26350611.
• Hallsworth K, Thoma C, Hollingsworth K G, Cassidy S, Anstee Q M, Day C P, Trenell M I. Modified high-intensity interval training reduces liver fat and improves cardiac function in non-alcoholic fatty liver disease: A randomised controlled trial. Clin Sci (Lond). 2015 Dec;129(12):1097-105. doi: 10.1042/CS20150308. Epub 2015 Aug 11.
• Jopson L, Newton JL, Palmer J, Trenell M, Blamire A, Howel D, Jones DE. RITPBC: B-Cell Depleting Therapy (Rituximab) as a Treatment for Fatigue in Primary Biliary Cirrhosis: study protocol for a randomised controlled trial. In press BMJ Open (2015).

Neuroscience

• Sedley W, Parikh J, Edden RA, Tait V, Blamire A, Griffiths TD. Human Auditory Cortex Neurochemistry Reflects the Presence and Severity of Tinnitus. J Neurosci. 2015 Nov 4;35(44):14822-8. doi: 10.1523/JNEUROSCI.2695-15.2015.
• Basu A, Taylor PN, Forsyth EO, Blamire AM, Forsyth R. Structural connectivity in a paediatric case of anarchic hand syndrome. BMC Neurol. 2015; 15: 234. Published online 2015 Nov 14. doi: 10.1186/s12883-015-0477-z. PMCID: PMC4647609.
• Keogh MJ, Aribisala BS, He J, Tulip E, Butteriss D, Morris C, Gorman G, Horvath R, Chinnery PF, Blamire AM. Voxel based analysis in neuroferritinopathy expands the phenotype and determines radiological correlates of disease severity. J Neurol. 2015 Oct;262(10):2232-40. doi: 10.1007/s00415-015-7832-2. Epub 2015 Jul 4. PMID: 26142024.
• Wilson B, Kikuchi Y, Sun L, Hunter D, Dick F, Smith K, Thiele A, Griffiths T, Marslen-Wilson W.D, & Petkov CI. Auditory sequence processing reveals evolutionarily conserved regions of frontal cortex in human and nonhuman primates. Nature Communications 2015, 6: 8901 doi:10.1038/ncomms9901.
• Perrodin C, Kayser C, Abel T, Logothetis NK & Petkov CI. Who is that? Neuronal networks and mechanisms for identifying individuals. Trends in Cognitive Sciences, Dec 2015; 19, 783-796.

Physics 

• Thrippleton M, Parikh J, Bridget Harris, Marshall I, Semple S, Andrews, P, Wardlaw J and Marshall I, Reliability of the MR Brian Temperature mapping at 1.5T and 3T, NMR Biomed. 2014 Feb 27(2):183-90.
• Hussain R, Vogt SJ, Honari A, Hollingsworth KG, Sederman AJ, Mitchell J, Johns ML. Interfacial tension measurements using MRI drop shape analysis. Langmuir. 2014 Feb 18;30(6):1566-72. doi: 10.1021/la404635x. Epub 2014 Feb 6.
• De Luca E, Harvey P, Chalmers KH, Mishra A, Senanayake PK, Wilson IJ, Botta M, Fekete M, Blamire AM, Parker D. Characterisation and evaluation of paramagnetic fluorine labelled glycol chitosan conjugates for 19F and 1H magnetic resonance imaging. J Biol Inorg Chem. 19:215-227, (2014).
• Payne BA, Hollingsworth KG, Baxter J, Wilkins E, Lee V, Price DA, Trenell M, Chinnery PF. In vivo mitochondrial function in HIV-infected persons treated with contemporary anti-retroviral therapy: a magnetic resonance spectroscopy study. PLoS One. 2014 Jan 7;9(1):e84678. doi: 10.1371/journal.pone.0084678. eCollection 2014.

Brain Injury

• Moore SA, Hallsworth K, Jakovljevic DG, Blamire AM, He J, Ford GA, Rochester L, Trenell MI. Effects of Community Exercise Therapy on Metabolic, Brain, Physical, and Cognitive Function Following Stroke: A Randomized Controlled Pilot Trial. Neurorehabil Neural Repair. 2014 Dec 23. pii: 1545968314562116. [Epub ahead of print]. PMID: 25538152.
• Aribisala BS, Cowie CJ, He J, Wood J, Mendelow DA, Mitchell P, Blamire AM. A histogram-based similarity measure for quantitative magnetic resonance imaging: application in acute mild traumatic brain injury. J Comput Assist Tomogr. 2014 Nov-Dec;38(6):915-23. doi: 10.1097/RCT.0000000000000143. PMID: 25162292.
• Croall ID, Cowie C, He J, Peel A, Wood J, Aribisala BS, Mitchell P, Mendelow AD, Smith F, Millar D, Kelly T, Blamire AM. White Matter Correlates of Cognitive Dysfunction following Mild Traumatic Brain Injury. Neurology, in press (2014).

Cardiovascular

• Moore SA, Hallsworth K, Jakovljevic DG, Blamire AM, He J, Ford GA, Rochester L, Trenell MI. Effects of Community Exercise Therapy on Metabolic, Brain, Physical, and Cognitive Function Following Stroke: A Randomized Controlled Pilot Trial. Neurorehabil Neural Repair. 2014 Dec 23. pii: 1545968314562116. [Epub ahead of print]. PMID: 25538152.

Dementia

• O'Donovan J, Watson R, Colloby SJ, Blamire AM, O'Brien JT. Assessment of regional MR diffusion changes in dementia with Lewy bodies and Alzheimer's disease. Int Psychogeriatr 2014;26(4):627-635. doi: 10.1017/s1041610213002317 PMID: 24331205.
• Colloby SJ, O'Brien JT, Taylor JP. Patterns of cerebellar volume loss in dementia with Lewy bodies and Alzheimer's disease: A VBM-DARTEL study. Psychiatry Research-Neuroimaging 2014;223(3):187-191. doi: 10.1016/j.pscychresns.2014.06.006 PMID: 25037902.
• Lowther ER, O'Brien JT, Firbank MJ, Blamire AM. Lewy body compared with Alzheimer dementia is associated with decreased functional connectivity in resting state networks. Psychiatry Res. 2014 Sep 30;223(3):192-201. doi: 10.1016/j.pscychresns.2014.06.004. Epub 2014 Jun 27. PMID: 25035300.
• Peraza LR, Kaiser M, Firbank M, Graziadio S, Bonanni L, Onofrj M, Colloby SJ, Blamire A, O'Brien J, Taylor JP. fMRI resting state networks and their association with cognitive fluctuations in dementia with Lewy bodies. Neuroimage Clin. 2014 Mar 28;4:558-65. doi: 10.1016/j.nicl.2014.03.013. eCollection 2014. PMID: 24818081.

Diabetes

• Hodson K, DellaMan C, Smith FE, Thelwall PE, Cobelli C, Robson SC, Taylor R. Mechanism of insulin resistance in normal pregnancy. Horm Metab Res. 2013 Aug;45(8):567-71. doi: 10.1055/s-0033-1337988. Epub 2013 Apr 2. PMID: 23549674.
• Avery L, Sniehotta FF, Denton SJ, Steen N, McColl E, Taylor R, Trenell MI. Movement as Medicine for Type 2 Diabetes: protocol for an open pilot study and external pilot clustered randomised controlled trial to assess acceptability, feasibility and fidelity of a multifaceted behavioural intervention targeting physical activity in primary care. Trials 2014 Feb 3; 15:46. doi: 10.1186/1745-6215-15-46. PubMed PMID: 24491134.

Liver

• Hallsworth K, Thoma C, Moore S, Ploetz T, Anstee QM, Taylor R, Day CP, Trenell MI. Non-alcoholic fatty liver disease is associated with higher levels of objectively measured sedentary behaviour and lower levels of physical activity than matched healthy controls. Frontline Gastroenterol 2015; 6:44-51. doi:10.1136/flgastro-2014-100432.
• Thelwall PE, Smith FE, Leavitt MC, Canty D, Hu W, Hollingsworth KG, Thoma C, Trenell MI, Taylor R, Rutkowski JV, Blamire AM, Quinn AG. Hepatic Cholesteryl Ester Accumulation in Lysosomal Acid Lipase Deficiency: Non-invasive Identification and Treatment Monitoring by Magnetic Resonance. J Hepatol. 2013 Sep;59(3):543-9. doi: 10.1016/j.jhep.2013.04.016. Epub 2013 Apr 25. PubMed PMID: 23624251.
• Hallsworth K, Hollingsworth KG, Thoma C, Jakovljevic D, Macgowan GA, Anstee QM, Taylor R, Day CP, Trenell MI. Cardiac structure and function are altered in adults with non-alcoholic fatty liver disease. J Hepatol. 2013 Apr;58(4):757-62. doi: 10.1016/j.jhep.2012.11.015. Epub 2012 Nov 22. PubMed PMID: 23178979.

Muscle

• Hollingsworth KG, Higgins DM, McCallum M, Ward L, Coombs A, Straub V. Investigating the quantitative fidelity of prospectively undersampled chemical shift imaging in muscular dystrophy with compressed sensing and parallel imaging reconstruction. Magn Reson Med. 2014 Dec;72(6):1610-9. doi: 10.1002/mrm.25072. Epub 2013 Dec 17.
• Hollingsworth KG. Quantitative MRI in muscular dystrophy: An indispensable trial endpoint? Neurology. 2014 Sep 9;83(11):956-7. doi: 10.1212/WNL.0000000000000785. Epub 2014 Aug 6.
• Willis TA, Hollingsworth KG, Coombs A, Sveen ML, Andersen S, Stojkovic T, Eagle M, Mayhew A, de Sousa PL, Dewar L, Morrow JM, Sinclair CD, Thornton JS, Bushby K, Lochmuller H, Hanna MG, Hogrel JY, Carlier PG, Vissing J, Straub V. Quantitative magnetic resonance imaging in limb-girdle muscular dystrophy 2I: a multinational cross-sectional study. PLoS One. 2014 Feb 28;9(2):e90377. doi: 10.1371/journal.pone.0090377. eCollection 2014.

Cardiovascular

• Hollingsworth KG, Willis TA, Bates MG, Dixon BJ, Lochmüller H, Bushby K, Bourke J, Macgowan GA, Straub V. Subepicardial dysfunction leads to global left ventricular systolic impairment in patients with limb girdle muscular dystrophy 2I. Eur J Heart Fail. 2013 Apr 10. [Epub ahead of print]
• Hallsworth K, Hollingsworth KG, Thoma C, Jakovljevic D, Macgowan GA, Anstee QM, Taylor R, Day CP, Trenell MI. Cardiac structure and function are altered in adults with non-alcoholic fatty liver disease. J Hepatol. 2012 Nov 22. pii: S0168-8278(12)00884-7. doi: 10.1016/j.jhep.2012.11.015. [Epub ahead of print]
• Bates, M. G., J. H. Newman, D. G. Jakovljevic, K. G. Hollingsworth, C. L. Alston, P. Zalewski, J. J. Klawe, et al. "Defining Cardiac Adaptations and Safety of Endurance Training in Patients with M.3243a>G-Related Mitochondrial Disease." [In eng]. Int J Cardiol 168, no. 4 (Oct 9 2013): 3599-608.
  
• Bates, M. G., K. G. Hollingsworth, J. H. Newman, D. G. Jakovljevic, A. M. Blamire, G. A. MacGowan, B. D. Keavney, et al. "Concentric Hypertrophic Remodelling and Subendocardial Dysfunction in Mitochondrial DNA Point Mutation Carriers." [In eng]. Eur Heart J Cardiovasc Imaging 14, no. 7 (Jul 2013): 650-8.

Dementia

• O'Donovan J, Watson R, Colloby SJ, Firbank MJ, Burton EJ, Barber R, Blamire AM, O'Brien JT. Does posterior cortical atrophy on MRI discriminate between Alzheimer's disease, dementia with Lewy bodies, and normal aging? Int Psychogeriatr. 2013 Jan;25(1):111-9. doi: 10.1017/S1041610212001214. PMID: 22809815.
• Kenny ER, O'Brien JT, Firbank MJ, Blamire AM. Subcortical connectivity in dementia with Lewy bodies and Alzheimer's disease. British Journal of Psychiatry 2013;203(3):209-214. doi: 10.1192/bjp.bp.112.108464 PMID: 23846997.
• Wood JS, Watson R, Firbank MJ, Mosimann UP, Barber R, Blamire AM, O’Brien JT. Longitudinal testing of visual perception in dementia with Lewy bodies and Alzheimer’s disease. International Journal of Geriatric Psychiatry. 2013, 28(6):567-572 doi: 10.1002/gps.3860 PMID: 22821711.

Diabetes

• Taylor R. Type 2 Diabetes: Etiology and Reversibility. Diabetes Care. 2013 Apr;36(4):1047-55. doi: 10.2337/dc12-1805. PubMed PMID: 23520370.
• Taylor R. Reversing the Twin Cycles of Type 2 Diabetes: The Banting Lecture 2012. Diabet Med. 2013 Mar;30(3):267-75. doi: 10.1111/dme.12039. PubMed PMID: 23075228.
• Steven S, Lim EL, Taylor R. Population response to information on reversibility of Type 2 diabetes. Diabet Med. 2013 Jan 15. doi: 10.1111/dme.12116. [Epub ahead of print].
• Knop F, Taylor R. Mechanism of metabolic advantage after bariatric surgery - it’s all gastrointestinal factors vs. it’s all food restriction. Diabetes Care. 2013 Aug;36 Suppl 2:S287-91. doi: 10.2337/dcS13-2032. PubMed PMID: 23882061.

Liver

• Thelwall PE, Smith FE, Leavitt MC, Canty D, Hu W, Hollingsworth KG, Thoma C, Trenell MI, Taylor R, Rutkowski JV, Blamire AM, Quinn AG. Hepatic Cholesteryl Ester Accumulation in Lysosomal Acid Lipase Deficiency: Non-invasive Identification and Treatment Monitoring by Magnetic Resonance. J Hepatol. 2013 Sep;59(3):543-9. doi: 10.1016/j.jhep.2013.04.016. Epub 2013 Apr 25. PubMed PMID: 23624251.
• Hallsworth K, Hollingsworth KG, Thoma C, Jakovljevic D, Macgowan GA, Anstee QM, Taylor R, Day CP, Trenell MI. Cardiac structure and function are altered in adults with non-alcoholic fatty liver disease. J Hepatol. 2013 Apr;58(4):757-62. doi: 10.1016/j.jhep.2012.11.015. Epub 2012 Nov 22. PubMed PMID: 23178979.

Muscle

• Hollingsworth KG, Garrood P, Eagle M, Bushby K, Straub V. Magnetic resonance imaging in duchenne muscular dystrophy: Longitudinal assessment of natural history over 18 months. Muscle Nerve. 2013 Oct;48(4):586-8. doi: 10.1002/mus.23879. Epub 2013 Aug 30. PubMed PMID: 23620230. 
• Willis TA, Hollingsworth KG, Coombs A, Sveen ML, Andersen S, Stojkovic T, Eagle M, Mayhew A, de Sousa PL, Dewar L, Morrow JM, Sinclair CD, Thornton JS, Bushby K, Lochmüller H, Hanna MG, Hogrel JY, Carlier PG, Vissing J, Straub V. Quantitative muscle MRI as an assessment tool for monitoring disease progression in LGMD2I: a multicentre longitudinal study. PLoS One. 2013 Aug 14;8(8):e70993. doi: 10.1371/journal.pone.0070993. eCollection 2013.
• Sinha A, Hollingsworth KG, Ball S, Cheetham T. Improving the vitamin d status of vitamin d deficient adults is associated with improved mitochondrial oxidative function in skeletal muscle.
  J Clin Endocrinol Metab. 2013 Mar;98(3):E509-13. doi: 10.1210/jc.2012-3592. Epub 2013 Feb 7.
• He J, Hollingsworth KG, Newton JL, Blamire AM. Cerebral vascular control is associated with skeletal muscle pH in chronic fatigue syndrome patients both at rest and during dynamic stimulation. NeuroImage 2013 Jan 5;2:168-73. doi: 10.1016/j.nicl.2012.12.006. PubMed PMID: 24179772.
• Ford AH, Duncan GW, Firbank MJ, Yarnall AJ, Khoo TK, Burn DJ, O'Brien JT.Rapid eye movement sleep behavior disorder in Parkinson's disease: Magnetic resonance imaging study. Mov Disord. 2013 Feb 28. doi: 10.1002/mds.25367. [Epubahead of print] PubMed PMID: 23450684.

Neuroscience

• Cousins DA, Aribisala BS, Ferrier IN, Blamire AM. Lithium, grey matter and the magnetic resonance signal. Biological Psychiatry. 2013 Apr 1;73(7):652-7. doi: 10.1016/j.biopsych.2012.09.029. Epub 2012 Nov 16. PubMed PMID: 23158114.
• Petkov CI & Vuong Q. Neuronal coding: The value in having an average voice. Curr Biol. 2013 Jun 17;23(12):R521-3. doi: 10.1016/j.cub.2013.04.077. PMID: 23787046.
• Petkov CI & Belin P. Silent reading: Does the brain ‘hear’ speech and voices? Curr Biol. 2013 Feb 18;23(4):R155-6. doi: 10.1016/j.cub.2013.01.002. PMID: 23428326.

Brain Injury

• Blamire AM. Seeing into the traumatically injured brain: Diffuse tissue damage and cognition. Neurology 2012 Mar 20;78(12):844-5. (*Invited review). Epub 2012 Feb 15. PMID:22345220

Cardiovascular

• Hollingsworth KG, Hodgson T, MacGowan GA, Blamire AM, Newton JL. Impaired cardiac function in chronic fatigue syndrome measured using magnetic resonance cardiac tagging. Journal of Internal Medicine. 2012 Mar;271(3):264-70.
• Hollingsworth KG, Gorman GS, Trenell MI, McFarland R, Taylor RW, Turnbull DM, Macgowan GA, Blamire AM, Chinnery PF. Cardiomyopathy is common in patients with the mitochondrial DNA m.3243A>G mutation and correlates with mutation load. Neuromuscul Disord. 2012 Jul;22(7):592-6. Epub 2012 Apr 17. PMID:22513320
• Hollingsworth KG, Macgowan GA, Morris L, Bates MG, Taylor R, Jones DE, Newton JL, Blamire AM. Cardiac torsion-strain relationships in fatigued Primary Biliary Cirrhosis patients show accelerated ageing: a pilot cross-sectional study. J Appl Physiol. 2012 Jun;112(12):2043-8. Epub 2012 Mar 29.
• Hollingsworth KG, Blamire AM, Keavney BD, Macgowan GA. Left ventricular torsion, energetics, and diastolic function in normal human aging. Am J Physiol Heart Circ Physiol. 2012 Feb;302(4):H885-92. Epub 2011 Dec 16. PMID: 22180656 
• Bates MG, Hollingsworth KG, Newman JH, Jakovljevic DG, Blamire AM, Macgowan GA, Keavney BD, Chinnery PF, Turnbull DM, Taylor RW, Trenell MI, Gorman GS. Concentric hypertrophic remodelling and subendocardial dysfunction in mitochondrial DNA point mutation carriers. Eur Heart J Cardiovasc Imaging. 2012 Nov 4. [Epub ahead of print]
• Hollingsworth KG, de Sousa PL, Straub V, Carlier PG. Towards harmonization of protocols for MRI outcome measures in skeletal muscle studies: consensus recommendations from two TREAT-NMD NMR workshops, 2 May 2010, Stockholm, Sweden, 1-2 October 2009, Paris, France. Neuromuscul Disord. 2012 Oct 1;22 Suppl 2:S54-67. doi: 10.1016/j.nmd.2012.06.005.PMID:22980769

Dementia

• Kenny ER, Blamire AM, Firbank MJ, O'Brien JT. Functional connectivity in cortical regions in dementia with Lewy bodies and Alzheimer's disease. Brain. 2012 Feb;135:569-81. doi: 10.1093/brain/awr327 PMID: 22189566.
• Taylor JP, Firbank MJ, He J, Barnett N, Pearce S, Livingstone A, Vuong Q, McKeith IG, O'Brien JT. Visual cortex in dementia with Lewy bodies: magnetic resonance imaging study. Br J Psychiatry. 2012 200(6):491-498. doi: 10.1192/bjp.bp.111.099432 PubMed PMID: 22500014.
• Lopes MA, Firbank MJ, Widdrington M, Blamire AM, Kalaria RN and O'Brien JT. Post-stroke dementia: the contribution of thalamus and basal ganglia changes, International Psychogeriatrics, 2012, 24(4), pp. 568-576.
• Firbank MJ, Teodorczuk A, van der Flier WM, Gouw AA, Wallin A, Erkinjuntti T, Inzitari D, Wahlund LO, Pantoni L, Poggesi A, Pracucci G, Langhorne P, O'BrienJT; the LADIS group. Relationship between progression of brain white matter changes and late-life depression: 3-year results from the LADIS study. Br J Psychiatry. 2012 201(1):40-45. doi: 10.1192/bjp.bp.111.098897 PubMed PMID: 22626634.
• Vasudev A, Saxby BK, OʼBrien JT, Colloby SJ, Firbank MJ, Brooker H, Wesnes K, Thomas AJ. Relationship Between Cognition, Magnetic Resonance White MatterHyperintensities, and Cardiovascular Autonomic Changes in Late-Life Depression.Am J Geriatr Psychiatry. 2012 20(8):691-699. doi: 10.1097/JGP.0b013e31824c0435 PubMed PMID: 22609766.
• Watson R, O'Brien JT, Barber R and Blamire AM. Patterns of gray matter atrophy in dementia with Lewy bodies: a voxel-based morphometry study', International Psychogeriatrics, 2012 24(4), pp. 532-540.
• Taylor JP and O'Brien JT. Neuroimaging of Dementia with Lewy Bodies, Neuroimaging Clinics of North America, 2012, 22(1), pp. 67-81.
• Colloby SJ, Firbank MJ, He J, Thomas AJ, Vasudev A, Parry SW and O'Brien, JT. Regional cerebral blood flow in late-life depression: arterial spin labelling magnetic resonance study , Br J Psychiatry. 2012 Feb;200(2):150-5. Epub 2011 Dec 22. PubMed PMID: 22194184.
• Watson R, Blamire AM, Colloby SJ, Wood JS, Barber R, He J and O’Brien JT. (2012) Characterising dementia with Lewy bodies by means of diffusion tensor imaging. Neurology 79(9): 906-14.

Diabetes

• Taylor R. Insulin resistance and type 2 diabetes. Diabetes. 2012 Apr;61(4):778-9. doi: 10.2337/db12-0073. PubMed PMID: 22442298.

Liver

• Jones DEJ, Hollingsworth KG, Jakovljevic DG, Fattakhova G, Pairman J, Blamire AM, et al. Loss of capacity to recover from acidosis on repeat exercise in chronic fatigue syndrome: a case-control study. European Journal of Clinical Investigation. 2012 Feb;42(2):186-94.
• Smith FE, Mardini H, Record CO and Blamire AM. Reply to: "Ammonia and cerebral water. Importance of structural analysis of the brain in hepatic encephalopathy"', Journal of Hepatology, 2012, 56(2), pp. 506-507.

Neuroscience

• Cousins DA, Grunze H. Interpreting magnetic resonance imaging findings in bipolar disorder. CNS Neurosci. Ther. 2012 Mar;18(3):201-7. PMID:22449107.
• Blamire AM. The Yale experience in first advancing fMRI. Neuroimage. 2012 Aug 15;62(2):637-40. Epub 2011 Oct 18.
• Smith FE, Mardini H, Record CO and Blamire AM. Reply to: "Ammonia and cerebral water. Importance of structural analysis of the brain in hepatic encephalopathy"', Journal of Hepatology, 2012, 56(2), pp. 506-507.
• McNeill A, Gorman G, Khan A, Horvath R, Blamire AM, Chinnery PF. Progressive Brain Iron Accumulation in Neuroferritinopathy Measured by the Thalamic T2* Relaxation Rate. AJNR Am J Neuroradiol. 2012 Apr 12. [Epub ahead of print]
• McAleese KE, Firbank M, Hunter D, Sun L, Hall R, Neal JW, Mann DM, Esiri M, Jellinger KA, O'Brien JT, Attems J. Magnetic resonance imaging of fixed post mortem brains reliably reflects subcortical vascular pathology of frontal, parietal and occipital white matter. Neuropathol Appl Neurobiol. 2012 Oct 17. doi: 10.1111/j.1365-2990.2012.01310.x. [Epub ahead of print] PubMed PMID: 23075072.

Physics 

• Smith FE, Cousins DA, Thelwall PE, Ferrier IN, Blamire AM. Quantitative Lithium Magnetic Resonance Spectroscopy in the Normal Human Brain on a 3T Clinical Scanner. Magnetic Resonance in Medicine. 2011; 66(4):945-9
• Chalmers KH, Kenwright AM, Parker D, Blamire AM. 19F-lanthanide complexes with increased sensitivity for 19F-MRI: Optimization of the MR acquisition. Magn Reson Med. 2011; 66(4):931-6
• Aribisala BS, He J, Blamire AM. Comparative Study of Standard Space and Real Space Analysis of Quantitative MR Brain Data. Journal of Magnetic Resonance in Imaging. 2011;33(6):1503-9
• Smart SD, Firbank MJ, O'Brien JT. Validation of automated white matter hyperintensity segmentation. J Aging Res. 2011;2011:391783. Epub 2011 Sep 6. PubMed PMID: 21904678; PubMed Central PMCID: PMC3167190.

Dementia

• Wood JS, Firbank MJ, Mosimann UP, Barber R, Watson R, Blamire AM, O’Brien JT. Testing visual perception in dementia with Lewy bodies and Alzheimer’s disease. American Journal of Geriatric Psychiatry 2011; 24:73-83
• Wood J, Firbank MJ, Mosimann UP, Taylor J-P, O’Brien JT. Development of a novel fMRI compatible visual perception prototype battery to test older people with and without dementia. Journal of Geriatric Psychiatry and Neurology 2011; 24(2) 73-83.
• Firbank MJ, He Jiabao, Blamire AM, Singh B, Danson P, Rajesh N. Kalaria, et al. Cerebral blood flow by arterial spin labelling in post stroke dementia. Neurology 2011; 76: 1478-1484
• Firbank MJ, Blamire AM, Teodorczuk A, Teper E, Mitra D, O'Brien JT. Diffusion tensor imaging in Alzheimer's disease and dementia with Lewy bodies. Psychiatry Res. 2011 194(2):176-83
• Marcos AL, Firbank MJ Widdrington M, Blamire AM, Kalaria RN, O’Brien JT. Post-stroke dementia: the contribution of thalamus and basal ganglia changes. Int Pyschogeriatrics, in press (2011).

Diabetes

• Lim EL, Hollingsworth KG, Aribisala BS, Chen MJ, Mathers JC, Taylor R. Reversal of type 2 diabetes: normalisation of beta cell function in association with decreased pancreas and liver triacylglycerol. Diabetologia. 2011 Jun 9.
• Lim EL, Hollingsworth KG, Smith F, Thelwall PE, Taylor R. Inhibition of lipolysis in type 2 diabetes normalizes glucose disposal without change in muscle glycogen synthesis rates. Clin. Sci. 2011; 121: 169-177.
• Lim EL, Hollingsworth KG, Smith F, Thelwall PE, Taylor R. Effects of raising muscle glycogen synthesis on skeletal muscle ATP turnover rate in type 2 diabetes. American J Physiology 2011 PMID 21917633.
• Thelwall PE, Taylor R, Marshall SM. Non-invasive investigation of kidney disease in Type 1 diabetes by magnetic resonance imaging. Diabetologia 2011; 54(9):2421-9.
• Taylor R. Reversing Type 2 diabetes. Practical Diabetes 2011; 28: 377-378.

Liver

• Hollingsworth KG, Lim EL, Coombs A, Taylor R. Reproducibility of liver and pancreatic fat measurement in type 2 diabetes and normal subjects using the 3 point Dixon technique. Submitted 2011.
• Hallsworth K, Fattakhova G, Hollingsworth KG, Thoma C, Moore S, Taylor R ,Day CP, Trenell MI. Resistance exercise reduces liver fat and its mediators in non-alcoholic fatty liver disease independent of weight loss. Hepatology Gut 2011;60:1278e1283. doi:10.1136/gut.2011.242073
• Mardini H, Smith FE, Record C, Blamire AM. Magnetic resonance quantification of water and metabolites in the brain of cirrhotics following induced hyperammonaemia. J Hepatol. 2011; 54: 1154-1160

Muscle

• Kinali M, Arechavala-Gomeza V, Cirak S, Glover A, Guglieri M, Feng L, Hollingsworth KG, Hunt D, Junbluth H, Roper HP, Quinlivin RM, Gosalakkal JA, Jayawant S, Nadeau A, Hughes-Carre L, Manzur AY, Mercuri E, Morgan JE, Straub V, Bushby K, Sewry C, Rutherford M, Muntoni F. Muscle histology va MRI in Duchenne muscular dystrophy. Neurology. 2011 Jan 25;76(4):346-53.
• Hallsworth K, Fattakhova G, Hollingsworth KG, Thoma C, Moore S, Taylor R ,Day CP, Trenell MI. Resistance exercise reduces liver fat and its mediators in non-alcoholic fatty liver disease independent of weight loss. Hepatology Gut 2011;60:1278e1283. doi:10.1136/gut.2011.242073.
• Yu-Wai-Man P, Trenell MI, Hollingsworth KG, Griffiths PG, PF. C. OPA1 mutations impair mitochondrial function in both pure and complicated dominant optic atrophy Brain. 2011; Apr;134(Pt 4):e164.Epub 2010 Oct 14.
• Klein A, Jungbluth H, Clement E, Lillis S, Abbs S, Munot P, Pane M, Wraige E, Schara U, Straub V, Mercuri E and Muntoni F. Muscle Magnetic Resonance Imaging in Congenital Myopathies Due to Ryanodine Receptor Type 1 Gene Mutations, Archives of Neurology, 2011, 68(9), pp. 1171-1179.

Neuroscience

• Mardini H, Smith FE, Record C, Blamire AM. Magnetic resonance quantification of water and metabolites in the brain of cirrhotics following induced hyperammonaemia. J Hepatol. 2011; 54: 1154-1160

Physics 

• He J, Blamire AM. Application of variable-rate selective excitation pulses for spin labelling in perfusion MRI. Magn Reson Med. 2010 Vol.63:842-84 7
• Chalmers KH, De Luca E, Hogg NHM, Kenwright AM, Kuprov I, Parker D, Botta M, Wilson JI, Blamire, AM. Design Principles and Theory of Paramagnetic Fluorine Labelled Lanthanide Complexes as Probes for 19F Magnetic Resonance: a Proof of Concept Study. Eur J Chem 2010. Vol. 16: 134-148.

Brain Injury

• Aribisala BA, Cowie CJA, He J, Wood J, Mendelow AD, Mitchell P, et al. Multi-parametric Classification of Traumatic Brain Injury Patients Using Automatic Analysis of Quantitative MRI Scans. Lecture Notes in Computer Science. 2010;6326:51-9.

Dementia

• Firbank MJ, Blamire AM, Teodorczuk A, Teper E, Burton EJ, Mitra D, O’Brien JT. High resolution imaging of the medial temporal lobe in Alzheimer’s disease and dementia with Lewy bodies. J Alz Disease 2010; 21: 1129-1140.
• Kenny ER, O’Brien JT, Cousins D, Richardson J, Thomas A, Firbank MJ, Blamire AM. Functional Connectivity in Late-life Depression using Resting-state Functional Magnetic Resonance Imaging. Am J Geriatric Psychiatry 2010 Jul;18(7):643-51.

Diabetes

• Lim EL, Hollingsworth KG, Thelwall P, Taylor R. Measuring the acute effect of insulin infusion on ATP turnover rate in human skeletal muscle using phosphorus-31 magnetic resonance saturation transfer spectroscopy. NMR in Biomedicine 2010; 23:952-7.
• Chen MJ, Jovanovic A, Taylor R. Utilizing the Second-Meal Effect in Type 2 Diabetes: Practical Use of a Soya-Yogurt Snack. Diabetes Care 2010; 2552-54.
• Steven S, Lim EL, Taylor R. Reversal of type 2 diabetes. Diabetic Medicine 2010; 27: 724-725.
• Balasubramanian R, Gerrard J, Dalla Man C, Firbank MJ, Lane A, English PT, Cobelli C, Taylor R. Combination peroxisome proliferator-activated receptor gamma and alpha agonist treatment in type 2 diabetes prevents the beneficial pioglitazone effect on liver fat content. Diabetic Medicine 2010; 27:150-156.
• Hayes L, Pearce MS, Firbank MJ, Walker M, Taylor R, Unwin N. Do obese but metabolically normal women differ in intra-abdominal fat and physical activity levels from those with the expected metabolic abnormalities? A cross-sectional study. BMC Public Health. 2010; 10:723.

Liver

• Hollingsworth KG, Jones DEJ, Taylor R, Blamire AM, Newton JL. Impaired cardiovascular response to standing in chronic fatigue syndrome. European Journal of Clinical Investigation. 2010; 40(7):608-15.
• Hollingsworth KG, Jones DEJ, Taylor R, Frith J, Blamire AM, Newton JL. Impaired cerebral autoregulation in primary biliary cirrhosis: implications for the pathogenesis of cognitive decline. Liver International. 2010; 30:878-85.
• Hollingsworth KG, Newton JL, Robinson L, Taylor R, Blamire AM, Jones DE. Loss of capacity to recover from acidosis in repeat exercise is strongly associated with fatigue in Primary Biliary Cirrhosis J Hepatol 2010;53:155-161
• Jones D, Hollingsworth K, Taylor R, Blamire A, Newton J. Abnormalities in pH Handling by Peripheral Muscle and Potential Regulation by the Autonomic Nervous System in Chronic Fatigue Syndrome. Journal of Internal Medicine. 2010; Apr 267(4):394-401.
• Jones DE, Hollingsworth KG, Fattakhova G, MacGowan GA, Taylor R, Blamire AM, et al. Impaired cardiovascular function in Primary Biliary Cirrhosis. Am J Physiol Gastrointest Liver Physiol 2010 May; Vol.298(5):PG764-773.
• Newton J, Hollingsworth K, Taylor R, Blamire A, DE J. Loss of capacity to recover from acidosis in repeat exercise is strongly associated with fatigue in primary biliary cirrhosis. J Hepatol 2010; 53(1):155-61.

Muscle

• Jones D, Hollingsworth K, Taylor R, Blamire A, Newton J. Abnormalities in pH Handling by Peripheral Muscle and Potential Regulation by the Autonomic Nervous System in Chronic Fatigue Syndrome. Journal of Internal Medicine 2010; 267(4):394-401.
• Hollingsworth KG, Newton JL, Robinson L, Taylor R, Blamire AM, Jones DE. Loss of capacity to recover from acidosis in repeat exercise is strongly associated with fatigue in Primary Biliary Cirrhosis J Hepatol 2010;53:155-161.
• Yu-Wai-Man P, Trenell MI, Hollingsworth KG, Griffiths PG, PF. C. OPA1 mutations impair mitochondrial function in both pure and complicated dominant optic atrophy Brain. 2010(Oct. 14).

Neuroscience

• Palaniyappan L, Cousins DA. Brain Networks: Foundations and Futures in Bipolar Disorder Journal of Mental Health. 2010;19(2):157-67.
• Cousins DA, Brian Moore P, Watson S, Harrison L, Nicol Ferrier I, Young AH, et al. Pituitary volume and third ventricle width in euthymic patients with bipolar disorder. Psychoneuroendocrinology 2010; 35(7):1074-81. Epub 2010 Feb 19.

Physics

• Shepherd TM, Thelwall PE, Stanisz GJ, Blackband SJ. Aldehyde fixative solutions alter the water relaxation and diffusion properties of nervous tissue. Magnetic Resonance in Medicine. 2009; 62: 26-34.

Dementia

• Blamire AM, O’Brien JT. Magnetic resonance imaging in Lewy body dementias. Dementia and Geriatric Cognitive Disorders 2009; 28:493-506.

Diabetes

• Jovanovic A, Leverton E, Solanky B, Snaar JEM, Morris PEG, Taylor, R. The second meal phenomenon is associated with enhanced muscle glycogen storage. Clin. Sci. 2009 Jul 2;117(3):119-27.
• Jovanovic A, Gerrard, J., Taylor, R. The second meal phenomenon in type 2 diabetes. Diabetes Care 2009 Jul;32(7):1199-201.

Liver

• Hollingsworth KG, Jones DE, Aribisala BS, Thelwall PE, Taylor R, Newton JL, Blamire AM . Globus pallidus magnetization transfer ratio, T(1) and T(2) in primary biliary cirrhosis: relationship with disease stage and age. J Magn Reson Imaging. 2009 Apr;29(4):780-4.
• Hollingsworth KG, Newton JL, Blamire A, Taylor R, Jones DE. Loss of capacity to recover from acidosis on repeat exercise is strongly associated with fatigue in primary biliary cirrhosis (PBC) Hepatology. 2009;50(4):1504.
• Woodward JM, Priest AN, Hollingsworth KG, Lomas DJ. Clinical application of magnetic resonance spectroscopy of the liver in patients receiving long-term parenteral nutrition. J Parenter Enteral Nutr. 2009; 33:669-76.

Muscle

• Garrood P, Hollingsworth K, Eagle M, Aribisala B, Birchall D, Bushby K, et al. MR imaging in Duchenne muscular dystrophy: quantification of T1-weighted signal, contrast uptake and the effects of exercise. Journal of Magnetic Resonance Imaging. 2009 Nov;30(5):1130-8.
• Stevenson EJ TP, Thomas K, Smith F, Brand-Miller J, Trenell MI. Dietary glycemic index influences lipid oxidation but not muscle or liver glycogen oxidation during exercise. Am J Physiol Endocrinol Metab 2009; 296(5):E1140-7. Epub 2009 Feb 17.

Neuroscience

• Cousins DA, Butts K, Young AH. The role of dopamine in bipolar disorder. Bipolar Disord 2009; 11: 787-806. 2009.
• Shepherd TM, Thelwall PE, Stanisz GJ, Blackband SJ. Aldehyde fixative solutions alter the water relaxation and diffusion properties of nervous tissue. Magnetic Resonance in Medicine, 62: 26-34 (2009).

Physics

• Blamire AM. The technology of MRI - the next 10 years? British Journal of Radiology. 2008;81(968):601-17
• Firbank MJ, Barber R, Burton EJ, O’Brien, JT. 2008. Validation of a fully automated hippocampal segmentation method on patients with dementia. Human Brain Mapping. 29(12), 1442-1449. http://dx.doi.org/10.1002/hbm.20480

Dementia

• Firbank MJ, Barber, R., Burton, E.J., O’Brien, J.T., 2008. Validation of a fully automated hippocampal segmentation method on patients with dementia. Human Brain Mapping 29(12), 1442-1449.

Diabetes

• Taylor R. Pathogenesis of type 2 diabetes: tracing the reverse route from cure to cause. Diabetologia. 2008;51(10):1781-9.
• Trenell MI, Hollingsworth KG, Lim EL, Taylor R. Increased daily walking improves lipid oxidation without changes in mitochondrial function in type 2 diabetes. Diabetes Care. 2008 Aug;31(8):1644-9.
• Sorensen L, Siddall PJ, Trenell MI, Yue DK. Differences in Metabolites in Pain-Processing Brain Regions in Patients With Diabetes and Painful Neuropathy. Diabetes Care. 2008 May 1, 2008;31(5):980-1.
• Lim, E; Trenell, MI; Hollingsworth, KG; Smith, FE; Thelwell, PE; Taylor, R. Is the sub-normal insulin stimulation of muscle ATP synthesis in type 2 diabetes always a consequence of low rates of muscle glycogen synthesis? Diabetologia 51: 766 (2008).
• Trenell, MI; Thelwall, P; Thomas, K; Stevenson, E. Effect of high and low glycaemic index diets on skeletal muscle and liver substrate storage and utilisation during exercise. Diabetologia 51: 248 (2008).
• Ravikumar B, Gerrard J, Man CD, Firbank MJ, Lane A, English PT, et al. Poglitazone decreases fasting and postprandial endogenous glucose production in proportion to decrease in hepatic triglyceride content. Diabetes 2008; 57(9):2288-95.

Liver

• Hollingsworth KG, Newton JL, Taylor R, McDonald C, Palmer JM, Blamire AM, et al. Pilot study of peripheral muscle function in primary biliary cirrhosis: potential implications for fatigue pathogenesis. Clin Gastroenterol Hepatol. 2008 Sep;6(9):1041-8.
• Newton JL, Hollingsworth KG, Taylor R, El-Sharkawy AM, Khan ZU, Pearce R, et al. Cognitive impairment in primary biliary cirrhosis: symptom impact and potential etiology. Hepatology. 2008 Aug;48(2):541-9.
• van der Poorten D, Milner K, Hui J, Hodge A, Trenell MI, Kench JG, et al. Visceral fat: a key mediator of steatohepatitis in metabolic liver disease. Hepatology. 2008;48(2):449-57.

Muscle

• Trenell MI, Thelwall P, Thomas K, Stevenson E. Effect of high and low glycaemic index diets on skeletal muscle and liver substrate storage and utilisation during exercise. Diabetologia 2008;51 248.
• Hollingsworth KG, Newton JL, Taylor R, McDonald C, Palmer JM, Blamire AM, et al. Pilot study of peripheral muscle function in primary biliary cirrhosis: potential implications for fatigue pathogenesis. Clin Gastroenterol Hepatol. 2008 Sep;6(9):1041-8.
• Trenell MI, Stevenson E, Stockmann K, Brand-Miller J. Effect of high and low glycaemic index recovery diets on intramuscular lipid oxidation during aerobic exercise. British Journal of Nutrition. 2008 Feb;99(2):326-32. Epub 2007 Aug 15.

Neuroscience

• Sibson NR, Lowe JP, Blamire AM, Martin MJ, Obrenovitch TP, Anthony DC. Acute astrocyte activation in brain detected by MRI: new insights into T-1 hypointensity (vol 28, pg 621, 2008). Journal of Cerebral Blood Flow and Metabolism. 2008;28(3):653.

Physics

• Thelwall PE. Detection of 17O-tagged phosphate by (31)P MRS: a method with potential for in vivo studies of phosphorus metabolism. Magnetic Resonance in Medicine. 2007; Jun;57(6):1168-72.
• Imaging lung ventilation by MRI of fluorocarbon gases
  Project Leader(s): Dr Peter Thelwall

Brain Injury

• Blamire AM, Cader S, Lee M, Palace J, Matthews PM. Axonal damage in the spinal cord of multiple sclerosis patients detected by magnetic resonance spectroscopy. Magnetic Resonance in Medicine 2007; 58:880-5.

Dementia

• Firbank MJ, Blamire AM, Krishnan MS, Teodorczuk A, English P, Gholkar A, et al. Atrophy is associated with posterior cingulate white matter disruption in dementia with Lewy bodies and Alzheimer's disease. Neuroimage. 2007;36(1):1-7.
• Firbank MJ, Blamire AM, Krishnan MS, Teodorczuk A, English P, Gholkar A, et al. Diffusion tensor imaging in dementia with Lewy bodies and Alzheimer's disease. Psychiatry Research-Neuroimaging. 2007;155(2):135-45.

Muscle

• Garrood P, Hollingsworth K, Thelwall P, Birchall D, Eagle M, Bushby K, et al. MRI in Duchenne muscular dystrophy: Quantification of fat infiltration and gadolinium uptake using whole-muscle regions of interest. Neuromuscular Disorders 2007; 17(9-10):816-7.

Neuroscience

• Cousins DA, Young AH. The armamentarium of treatments for bipolar disorder: a review of the literature. Int J Neuropsychopharmacol. 2007 Jun;10(3):411-31. Epub 2006 Dec 19. PubMed PMID: 17176493.
• Garrood P, Hollingsworth K, Thelwall P, Birchall D, Eagle M, Bushby K, et al. MRI in Duchenne muscular dystrophy: Quantification of fat infiltration and gadolinium uptake using whole-muscle regions of interest. Neuromuscular Disorders. 2007;17(9-10):816-7.
• Blamire AM, Cader S, Lee M, Palace J, Matthews PM. Axonal damage in the spinal cord of multiple sclerosis patients detected by magnetic resonance spectroscopy. Magnetic Resonance in Medicine. 2007;58:880-5.

Oncology

• Zahra MA, Hollingsworth KG, Sala E, Lomas DJ, Tan LT. Dynamic contrast-enhanced MRI as a predictor of tumour response to radiotherapy. Lancet Oncology 2007; 8(1), 63-74.

Neuroscience

• El-Badri SM, Cousins DA , Parker S, Ashton HC. McAllister VL, Ferrier IN, Moore PB. Magnetic resonance imaging abnormalities in young euthymic patients with bipolar affective disorder. [Journal Article. Multicenter Study. Research Support, Non-U.S. Gov't] British Journal of Psychiatry. July 2006 189:81-2. UI: 16816311

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