Bio-Imaging Unit

VisiTech iSIM

VisiTech iSIM


The VisiTech iSIM confocal is an array-scanning confocal microscope based around a fully motorized, inverted Nikon TiE body.

The system has two Hamamatsu Orca Flash 4 sCMOS monochrome cameras for simultaneous two colour fluorescence imaging.

The system is run through Nikon’s versatile Elements software package and incorporates wizards to perform common imaging tasks.


Here you can find the specifications for this microscope.

Example objectives

LensImmersionNA (mm)
100x Oil 1.49
40x Air 0.95
20x Air 0.75

Imaging modes

  • multi point x,y (2D) with tiling
  • volume x,y,z (3D)
  • time lapse x,y,z,t (4D)
  • super resolution

Laser lines

  • 488nm
  • 561nm
  • 647nm


This microscope is located in the Central Unit, on campus.

The Central Unit is based in the Bioimaging Unit in the William Leech Building. Room M2.47a.

Newcastle University
William Leech Building
Medical School
Framlington Place 
Newcastle upon Tyne

Here, you can get directions to the building.

Enter your postcode or address to find directions


Find out how to book this microscope.

The minimal booking time for this equipment is 30 minutes. Time increments of 15 minutes are permitted.

Bookings can be cancelled with no charge up to an hour before scheduled use.

Before booking this equipment, please ensure the following:

  • any users are fully trained, and approved by a member of BioImaging facility staff
  • microscopes are left in a good state of tidiness (lenses/stage should be cleaned of any oil)
  • filters and lenses must not be removed or switched between systems without authorisation from Bioimaging facility staff

If you work at Newcastle University, you can book this microscope online by using iLab.

If you're a commercial company or an academic at another institution, just contact us to discuss your requirements.