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Interdisciplinary Computing and Complex BioSystems

A computational biology group with its own microbiology and nanotechnology wet labs and an intelligent biofoundry.

Interdisciplinary expertise

We carry out ground-breaking research at the interface of computer science and complex biological systems.

We create the next generation of algorithms that provide innovative solutions to problems arising in natural complex systems (such as biology, chemistry, physics). We also create synthetic systems (such as biological engineering, software engineering and healthcare) and derive new knowledge from them.


To accomplish its mission, the group pursues collaborative activities across disciplines. It also leverages its interdisciplinary expertise in:

  • machine intelligence
  • complex systems
  • computational biology

Research impact

The Interdisciplinary Computing and Complex BioSystems (ICOS) environment generates outputs in high quality and highly interdisciplinary areas. These areas include:

  • stem cells and tissue engineering
  • computer-driven neurological interventions
  • synthetic biology biotechnology
  • bio-medical informatics
  • DNA/RNA nanotechnology

Through translational activity our members have established a number of spinouts, including:

  • CellRepo: a global repository for cell engineering
  • Workli: projects and collaboration platform for deep work

Several of our researchers have started their own companies in nano-biotech (e.g. Nanovery). Others are making digital pathology available in developing countries.

Recent research projects

AI-enabled RNA nanotechnology delivery system for information transfer into cells (DESTINATION)

Funding body: EU

Amount awarded: £3,381,888

Duration: 2021-2025 (48 months)

 

Therapeutics DNA/RNA nanostructures

Funding body: Innovate UK

Amount awarded: £64,000

Duration: 2021-2024 (36 months)

 

Engineering data structures organelles (EnDROIDS) - Chair in Emerging Technologies

Funding body: RAoE

Amount awarded: £2,738,988

Duration: 2020-2030 (120 months)

 

Design the Future 2: Thinking Soils - engineered bacteria as computational agents in the design and manufacture of new materials and structures

Funding body: EPSRC

Amount awarded: £598,309

Duration: 2017-2022 (60 months)

 

Synthetic Portabolomics: Leading the way at the crossroads of the digital and the bio economies

Funding body: EPSRC

Amount awarded: £4,353,851

Duration: 2016-2022 (71 months)

 

Personalised ultraviolet B (UVB) treatment of psoriasis through biomarker integration with computational modelling of psoriatic plaque resolution

Funding body: RT

Amount awarded: £248,566

Duration: 2016-2019 (36 months)

 

Critical: Combatting criminals in the cloud

Funding body: EPSRC

Amount awarded: £2,027,646

Duration: 2015-2022 (85 months)

Teaching

Our MSc in Bioinformatics is unique and interdisciplinary programme combining biology and computer science to analyse and interpret biological data.

It brings together highly rated teaching and research expertise from across the University. It'll equip you for a successful career in the bioinformatics industry or academia.

We've designed this programme for students from life science backgrounds, but we also welcome applications from students with other scientific backgrounds, including:

  • computing
  • mathematical
  • engineering

Collaborators

ICOS acts as an interdisciplinary collaboration hub. Our Portabolomics Programme Grant involved six different research groups across three NU faculties.

Our members conduct internationally leading research with a global network of collaborating institutions. 

List of our collaborators
  • Boston University
  • Utah University
  • Kobe University
  • NUS
  • BBN-Raytheon
  • Procter & Gamble
  • Prozomix
  • GSK
  • CERN
  • ECLT
  • Weizmann Institute
  • Tel Aviv University
  • Granada University
  • Centro Nacional de Biotechnologia
  • SRC
  • Huawei
  • Sixfold Bio
  • Nanovery
  • CPI
  • PROIMI