Staff profiles

Experienced Senior Trial Manager with leadership across CTIMPs, device, surgical and other interventional studies in a wide range of therapeutic areas, including mental health. Particular expertise includes delivery of complex methodological trials in rare diseases and I am a member of the LifeArc Centre for the Acceleration of Rare Disease Trials team. I provide methodology advice to funding applications via the RSS North East and North Cumbria. Academic contributions include co‑leading the Newcastle University postgraduate Integrity, Infrastructure and Information Governance in Healthcare Research module and co-supervision of a PhD student. Additional roles include serving on the Newcastle University Faculty of Medical Sciences Research Ethics Committee and the UKTMN Professional Development Group.

Co-lead MCR8009: Integrity, Infrastructure & Information Governance in Healthcare Research (E-learning)

• Articles

  • Dunn S, Evans L, Kennedy C, Wafer R, Moody S, Wolstenhulme F, Burton E, Konkoth AB, Fisher H, Chadwick T, Banham A, Hale F, Christie M, Barclay ST, Dyson J, Smith R, Aithal G, Culver E, Aspinall R, Thorburn D, Heneghan M, Hancock HC, Trivedi P, Mells G, Wason J, Jones DEJ. Optimising Primary thErapy in pRimAry biliary cholangitis (OPERA): protocol for a randomised, double-blind, placebo-controlled trial of enhanced primary therapy with obeticholic acid. BMJ Open 2026, 16(3), e113812.
  • Wolstenhulme F, Bibby I, Cole M, Grixti L, McGregor N, Bradley P, Maier RH, Walker J, Pearce SH, Wason J. Graves-PCD: protocol for a randomised, dose-finding, adaptive trial of the plasma cell-depleting agent daratumumab in severe Graves' disease. BMJ Open 2024, 14(6), e079158.
  • Azim L, Hindmarch P, Browne G, Chadwick T, Clare E, Courtney P, Dixon L, Duffelen N, Fouweather T, Geddes JR, Goudie N, Harvey S, Helter T, Holstein EM, Martin G, Mawson P, McCaffery J, Morriss R, Simon J, Smith D, Stokes P, Walker J, Weetman C, Wolstenhulme F, Young AH, Watson S, McAllister-Williams H. Study protocol for a randomised placebo-controlled trial of pramipexole in addition to mood stabilisers for patients with treatment resistant bipolar depression (the PAX-BD study). BMC Psychiatry 2021, 21(21), 334.
  • Grahame V, Dixon L, Fletcher-Watson S, Garland D, Glod M, Goodwin J, Grayson Z, Heron S, Honey E, Iversen R, Kasim AS, Kernohan A, Kharatikoopaei E, Le Couteur A, Mackie L, Mathias A, Probert H, Riby D, Rob P, Rogan L, Thompson S, Vale L, Walls E, Webb EI, Weetman C, Wolstenhulme F, Wood R, Rodgers J. A clinical and cost-effectiveness trial of a parent group intervention to manage challenging restricted and repetitive behaviours in young children with autism spectrum disorder: study protocol for a randomised controlled trial. Trials 2021, 22(1), 240.
  • Buckingham F, Gouverneur V. Asymmetric ¹⁸F-Fluorination for Applications in Positron Emission Tomography. Chemical Science 2016, 7(3), 1645-1652.
  • Buckingham F, Calderwood S, Checa B, Keller T, Tredwell M, Collier TL, Newington IM, Bhalla R, Glaser M, Gouverneur V. Oxidative Fluorination of N-Arylsulfonamides. Journal of Fluorine Chemistry 2015, 180, 33-39.
  • Buckingham F, Kirjavainen AK, Forsback S, Krzyczmonik A, Keller T, Newington IM, Glaser M, Luthra SK, Solin O, Gouverneur V. Organomediated Enantioselective ¹⁸F Fluorination for PET Applications. Angewandte Chemie International Edition 2015, 54(45), 13366–13369.
  • Cowell J, Abualnaja M, Morton S, Linder R, Buckingham F, Waddell PG, Probert MR, Hall MJ. Diastereoselective synthesis of functionalised carbazoles via a sequential Diels-Alder/ene reaction strategy. RSC Advances 2015, 5(21), 16125-16152.

• Note

  • Mitchell EJ, Arundel C, Babalis D, Connolly S, Constable L, Goodman K, Stylianou L, Taylor J, Wakefield N, Williams S, Wolstenhulme F. Supporting the professional development of trial managers: how can you help?. Trials 2025, 26, 436.