CONFORM-OH
CONFORM-OH
Control, Fludrocortisone or Midodrine for the treatment of Orthostatic Hypotension: A Randomised Controlled Trial
• Status: Closedown/Analysis
• Sponsor: The Newcastle upon Tyne Hospitals NHS Foundation Trust
• Funder: NIHR HTA
• Therapeutic area: Cardiovascular
• Type of study: CTIMP
Aim: This trial will evaluate the clinical and cost effectiveness of three different treatment strategies for orthostatic hypotension.
Primary outcome:
To determine whether the treatment strategies of conservative management plus fludrocortisone, and conservative management plus midodrine improve symptoms of OH compared to conservative management alone.
• Clinical Phase: IV
• Population: Adults
• Design: RCT Adaptive
• Setting: Secondary Care
• Planned Sample Size: 366