Newcastle Clinical Trials Unit



THYRoxine in Acute Myocardial Infarction (ThyrAMI)

  • Study stage: Closed
  • Sponsor: Gateshead Health NHS Foundation Trust
  • Funder:  NIHR Fellowship
  • Therapeutic area: Cardiovascular
  • Type of study: CTIMP

Aim: To assess what proportion of individuals with AMI have thyroid dysfunction and whether thyroid function at the time of AMI is related to adverse vascular outcomes.

Primary Outcome:

The association between thyroid status at the time of AMI (within 24 hours of diagnosis) with vascular outcomes (another AMI, coronary revascularisation or death due to ischaemic heart disease) over 24 months.

  • Clinical Phase: IIII
  • Population: Adults
  • Design: Randomised Control Trial (RCT)
  • Setting: Secondary Care
  • Planned Sample Size: 100