Oral

ENHANCE_D - Recruiting

The ENHANCE-D Study – ENHANCing smoking cEssation interventions in Dentistry

• Study stage: Recruiting
• Sponsor: The Newcastle upon Tyne Hospitals NHS Foundation Trust
• Funder: NIHR HTA
• Therapeutic area: Oral
• Type of study: CTIMP

Aim:

To compare smoking abstinence at 6 months of Nicotine Replacement Therapy (NRT)  and  E-cigarette (EC) to usual care and to each other.

Primary Outcome:

Biochemically verified smoking abstinence at 6 months

• Clinical Phase: IIII
• Population: Adults
• Design: RCT
• Setting: Primary care (NHS Dental Care)
• Planned Sample Size: 1460

Fiction - Closed

Filling Children’s Teeth: Indicated or Not? 

• Study stage: Closed
• Sponsor:  University of Dundee
• Funder:  NIHR HTA
• Therapeutic area: Oral
• Type of study:  Clinical Intervention

Aim:

Compare these three treatment strategies, when applied over a period of up to three years to 3-7 year old children with caries in primary teeth, with respect to the clinical outcomes of incidence and number of episodes of dental pain and dental sepsis.

Primary Outcome:

Either pain or sepsis related to dental caries.

• Population: Paediatrics
• Design: RCT
• Setting: Primary care (NHS Dental Care)
• Planned Sample Size: 1113