Newcastle Clinical Trials Unit



ALTAR- Alternatives To prophylactic Antibiotics for the treatment of Recurrent urinary tract infection in women

  • Study stage: Closed
  • Sponsor: The Newcastle upon Tyne Hospitals NHS Foundation Trust
  • Funder: NIHR HTA
  • Therapeutic area: Renal and Urogenital
  • Type of study: CTIMP

Aim: A multicentre, pragmatic patient-randomised non-inferiority trial comparing two drugs for the prevention of recurrent urinary tract infection in women both during a 12-month period of use and in the subsequent 6-months following completion of the prophylactic medication. 

Primary outcome: To determine the relative clinical effectiveness and cost-effectiveness for the NHS of two types of licensed preventative treatments for women with recurrent uncomplicated urinary tract infection (rUTI) over a 12 month treatment period.

  • Population: Adult
  • Clinical Phase: Phase IV
  • Design: RCT, Qualitative and Health Economic
  • Setting: Secondary Care