Staff Profile

Qualifications

• PhD in Computational Neuroscience, Newcastle University, 2025.
• PGDip in Cloud Computing for Big Data, Newcastle University, 2020.
• BSc in Mathematics (First Class Honours), Lancaster University, 2014.

Areas of expertise: data science, brain imaging, epilepsy

Current research

My current projects focus on developing computational approaches to improve research and treatment of epilepsy. I use statistics and machine learning to identify epileptogenic (seizure-generating) brain regions, aiming to improve outcomes in epilepsy surgery.

Research interests

• Epilepsy
• Epilepsy surgery
• Normative modelling & statistics
• Machine learning & deep learning

• Articles

  • Taylor PN, Wang Y, Simpson C, Janiukstyte V, Horsley J, Leiberg K, Little B, Clifford H, Adler S, Vos SB, Winston GP, McEvoy AW, Miserocchi A, de Tisi J, Duncan JS. The Imaging Database for Epilepsy And Surgery (IDEAS). Epilepsia 2025, 66(2), 471-481.
  • Hall GR, Gascoigne SJ, Horsley JJ, Wang Y, Kozma C, De Tisi J, Vos SB, Winston GP, Duncan JS, Taylor PN. Superficial and deep white matter abnormalities in temporal lobe epilepsy. Brain Communications 2025, 7(5), fcaf305.
  • Horsley J, Hall G, Simpson C, Kozma C, Thomas R, Wang Y, de Tisi J, Miserocchi A, McEvoy A, Vos S, Winston G, Duncan J, Taylor PN. Seizure freedom after surgical resection of diffusion-weighted magnetic resonance imaging abnormalities. Epilepsia 2025, 66(9), 3480-3490.
  • Clifford HJ, Fenske S, Horsley J, Simpson C, Evans N, Wang Y, da Silva Costa T, Thomas RH, Iqbal S, Elliott CA, Duncan JS, Taylor PN. Hippocampal abnormality and response to vagus nerve stimulation in epilepsy. Epilepsia 2025, 66(12), e268-e275.
  • Simpson C, Horsley Jonathan, Janiukstyte V, Tisi J, Miserocchi A, McEvoy A, Wang Y, Duncan J, Taylor P. Do Larger Resections Cut It? Relating Temporal Lobe Epilepsy Surgery and Seizure Outcome. In: 47th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2025). 2025, Copenhagen, Denmark: IEEE.
  • Kozma C, Horsley J, Hall G, Simpson C, de Tisi J, Miserocchi A, McEvoy AW, Vos SB, Winston GP, Wang Y, Duncan JS, Taylor PN. Combined impact of gray and superficial white matter abnormalities: Implications for epilepsy surgery. Epilepsia 2025, 66(10), 3688-3699.
  • Horsley J, Wang Y, Simpson C, Janiukstyte V, Leiberg K, Little B, de Tisi J, Duncan J, Taylor PN. Status epilepticus and thinning of the entorhinal cortex. Epilepsy and Behavior 2024, 160, 110016.
  • Wang Y, Schroeder GM, Horsley JJ, Panagiotopoulou M, Chowdhury FA, Diehl B, Duncan JS, McEvoy AW, Miserocchi A, de Tisi J, Taylor PN. Temporal stability of intracranial electroencephalographic abnormality maps for localizing epileptogenic tissue. Epilepsia 2023, 64(8), 2070-2080.
  • Horsley JJ, Thomas RH, Chowdhury FA, Diehl B, McEvoy AW, Miserocchi A, de Tisi J, Vos SB, Walker MC, Winston GP, Duncan JS, Wang Y, Taylor PN. Complementary structural and functional abnormalities to localise epileptogenic tissue. eBioMedicine 2023, 97, 104848.
  • Horsley JJ, Schroeder GM, Thomas RH, de Tisi J, Vos SB, Winston GP, Duncan JS, Wang Y, Taylor PN. Volumetric and structural connectivity abnormalities co-localise in TLE. NeuroImage: Clinical 2022, 35, 103105.