Staff Profile

I am currently a Future Leaders Fellow in the School of Computing at Newcastle University. I am based in the Interdisciplinary Computing and Complex BioSystems research group.

The majority of my work is on mathematical/computational modelling and advanced data analytics in neurological disorders (primarily epilepsy).

My wider research interests currently also include neuroimaging and neuromorphology in health and disease.

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The majority of my work is on mathematical/computational modelling and advanced data analytics in neurological disorders (primarily epilepsy).

My wider research interests currently also include neuroimaging and neuromorphology in health and disease.

• Ramaraju S, Reichert S, Wang Y, Forsyth R, Taylor PN. Carbogen inhalation during Non-Convulsive Status Epilepticus: A quantitative exploratory analysis of EEG recordings. PLoS one 2021, 16(2), e0240507.
• Sinha N, Peternell N, Schroeder GM, deTisi J, Vos SB, Winston GP, Duncan JS, Wang Y, Taylor PN. Focal to bilateral tonic–clonic seizures are associated with widespread network abnormality in temporal lobe epilepsy. Epilepsia 2021, 62(3), 729-741.
• Wang Y, Leiberg K, Ludwig T, Little B, Necus JH, Winston G, Vos SB, Tisi JD, Duncan JS, Taylor PN, Mota B. Independent components of human brain morphology. NeuroImage 2021, 226, 117546.
• Owen TW, de Tisi J, Vos SB, Winston GP, Duncan JS, Wang Y, Taylor PN. Multivariate white matter alterations are associated with epilepsy duration. European Journal of Neuroscience 2021, 53(8), 2788-2803.
• Sinha N, Wang Y, da Silva NM, Miserocchi A, McEvoy AW, de Tisi J, Vos SB, Winston GP, Duncan JS, Taylor PN. Structural brain network abnormalities and the probability of seizure recurrence after epilepsy surgery. Neurology 2021, 96(5), e758-e771.
• Papasavvas CA, Schroeder GM, Diehl B, Baier G, Taylor PN, Wang Y. Band power modulation through intracranial EEG stimulation and its cross-session consistency. Journal of Neural Engineering 2020, 17(5), 054001.
• Papasavvas CA, Trevelyan AJ, Kaiser M, Wang Y. Divisive gain modulation enables flexible and rapid entrainment in a neocortical microcircuit model. Journal of Neurophysiology 2020, 123(3), 1133-1143.
• Wang Y, Sinha N, Schroeder GM, Ramaraju S, McEvoy AW, Miserocchi A, de Tisi J, Chowdhury FA, Diehl B, Duncan JS, Taylor PN. Interictal intracranial electroencephalography for predicting surgical success: The importance of space and time. Epilepsia 2020, 61(7), 1417-1426.
• Carmon J, Heege J, Necus JH, Owen TW, Pipa G, Kaiser M, Taylor PN, Wang Y. Reliability and comparability of human brain structural covariance networks. NeuroImage 2020, 220, 117104.
• Ramaraju S, Wang Y, Sinha N, McEvoy AW, Miserocchi A, de Tisi J, Duncan JS, Rugg-Gunn F, Taylor PN. Removal of Interictal MEG-Derived Network Hubs Is Associated With Postoperative Seizure Freedom. Frontiers in Neurology 2020, 11, 563847.
• Schroeder GM, Diehl B, Chowdhury FA, Duncan JS, de Tisi J, Trevelyan A, Forsyth R, Jackson A, Taylor PN, Wang Y. Seizure pathways change on circadian and slower timescales in individual patients with focal epilepsy. Proceedings of the National Academy of Sciences of the United States of America 2020, 117(20), 11048-11058.
• Uddin M, Wang Y, Woodbury-Smith MR. Artificial intelligence for precision medicine in neurodevelopmental disorders. npj Digital Medicine 2019, 2, 112.
• Sinha N, Wang Y, Dauwels J, Kaiser M, Thesene T, Forsyth R, Taylor PN. Computer modelling of connectivity change suggests epileptogenesis mechanisms in idiopathic generalised epilepsy. NeuroImage: Clinical 2019, 21, 101655.
• Taylor PN, da Silva NM, Blamire A, Wang Y, Forsyth RJ. Early deviation from normal structural connectivity: A novel intrinsic severity score for mild TBI. Neurology 2019, 94(10), e1021-e1026.
• Wang Y, Necus J, Peraza Rodriguez L, Taylor PN, Mota B. Human cortical folding across regions within individual brains follows universal scaling law. Communications Biology 2019, 2, 191.
• Necus J, Smith FE, Thelwall PE, Flowers CJ, Sinha N, Taylor PN, Blamire AM, Wang Y, Cousins DA. Quantification of brain proton longitudinal relaxation (T₁) in lithium‐treated and lithium‐naïve patients with bipolar disorder in comparison to healthy controls. Bipolar Disorders 2019, 23(1), 41-48.
• Necus J, Sinha N, Smith FE, Thelwall PE, Flowers CJ, Taylor PN, Blamire AM, Cousins DA, Wang Y. White matter microstructural properties in bipolar disorder in relationship to the spatial distribution of lithium in the brain. Journal of Affective Disorders 2019, 253, 224-231.
• França LGS, Miranda JGV, Leite M, Sharma NK, Walker MC, Lemieux L, Wang Y. Fractal and Multifractal Properties of Electrographic Recordings of Human Brain Activity: Toward Its Use as a Signal Feature for Machine Learning in Clinical Applications. Frontiers in Physiology 2018, 9, 1767.
• Cousins D, Smith F, Necus J, Thelwall P, Flowers C, Taylor P, Sinha N, Wang YJ, Blamire A. Imaging the distribution and effects of lithium in the brain in bipolar disorder. In: 73rd Annual Meeting of the Society of Biological Chemistry. 2018, New York: Elsevier.
• Taylor PN, Sinha N, Wang Y, Vos SB, deTisi J, Miserocchi A, McEvoy AW, Winston GP, Duncan JS. The impact of epilepsy surgery on the structural connectome and its relation to outcome. NeuroImage: Clinical 2018, 18, 202-214.
• Baier G, Rosch R, Taylor PN, Wang Y. Design principle for a population-based model of epileptic dynamics. In: Complexity and Synergetics. Berlin: Springer International Publishing, 2017, pp.333-347.
• Wang Y, Trevelyan AJ, Valentin A, Alarcon G, Taylor PN, Kaiser M. Mechanisms underlying different onset patterns of focal seizures. PLoS Computational Biology 2017, 13(5), e1005475.
• Sinha N, Dauwels J, Kaiser M, Cash SS, Westover MB, Wang Y, Taylor PN. Predicting neurosurgical outcomes in focal epilepsy patients using computational modelling. Brain 2017, 140(2), 319-332.
• Sinha N, Dauwels J, Kaiser M, Cash SS, Westover BM, Wang Y, Taylor PN. Reply: Computer models to inform epilepsy surgery strategies: Prediction of postoperative outcome. Brain 2017, 140(5), e31.
• Baier G, Taylor PN, Wang Y. Understanding Epileptiform After-Discharges as Rhythmic Oscillatory Transients. Frontiers in Computational Neuroscience 2017, 11, 25.
• Taylor PN, Wang Y, Kaiser M. Within brain area tractography suggests local modularity using high resolution connectomics. Scientific Reports 2017, 7, 39859.
• Wang Y, Necus J, Kaiser M, Mota B. Universality in human cortical folding in health and disease. Proceedings of the National Academy of Sciences of the USA 2016, 113(45), 12820-12825.
• Wang YJ, Hutchings F, Kaiser M. Computational modeling of neurostimulation in brain diseases. Progress in Brain Research 2015, 222, 191-228.
• Papasavvas CA, Wang Y, Trevelyan AJ, Kaiser M. Gain control through divisive inhibition prevents abrupt transition to chaos in a neural mass model. Physical Review E 2015, 92(3), 032723.
• Taylor PN, Wang Y, Goodfellow M, Dauwels J, Moeller F, Stephani U, Baier G. A Computational Study of Stimulus Driven Epileptic Seizure Abatement. PLoS ONE 2014, 9(12), e114316.
• Sinha N, Dauwels J, Wang Y, Cash SS, Taylor PN. An in silico approach for pre-surgical evaluation of an epileptic cortex. In: 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). 2014, Chicago, IL, USA: IEEE.
• Wang Y, Goodfellow M, Taylor PN, Baier G. Dynamic Mechanisms of Neocortical Focal Seizure Onset. PLoS Computational Biology 2014, 10(8), e1003787.
• Taylor PN, Baier G, Cash SS, Dauwels J, Slotine JJ, Wang Y. A model of stimulus induced epileptic spike-wave discharges. In: IEEE Computational Intelligence, Cognitive Algorithms, Mind, and Brain (CCMB). 2013, Singapore: IEEE.
• Wang Y, Taylor PN, Baier G. Computational modelling of micro-seizures and focal seizure onset. In: Twenty Second Annual Computational Neuroscience Meeting: CNS*2013. 2013, Paris, France: BioMed Central.
• Wang Y, Goodfellow M, Taylor PN, Garry D, Baier G. Computational modelling of microseizures and focal seizure onset. In: Recent Advances in Predicting and Preventing Epileptic Seizures. 2013.
• Taylor PN, Goodfellow M, Wang Y, Baier G. Towards a large-scale model of patient-specific epileptic spike-wave discharges. Biological Cybernetics 2013, 107(1), 83-94.
• Goodfellow M, Taylor PN, Wang Y, Garry DJ, Baier G. Modelling the role of tissue heterogeneity in epileptic rhythms. European Journal of Neuroscience 2012, 36(2), 2178-2187.
• Wang Y, Goodfellow M, Taylor PN, Baier G. Phase space approach for modeling of epileptic dynamics. Physical Review E 2012, 85(6), 061918.
• Baier G, Goodfellow M, Taylor PN, Wang Y, Garry DJ. The importance of modeling epileptic seizure dynamics as spatio-temporal patterns. Frontiers in Physiology 2012, 3, 281.