Solution-State Nuclear Magnetic Resonance Spectroscopy

Our nuclear magnetic resonance (NMR) spectrometers allow you to investigate the physical and chemical properties of atoms and molecules.

These facilities are managed by highly experienced researchers. The spectrometers are able to observe virtually all NMR-active nuclei and perform the most demanding NMR experiments.

The NMR facility underwent a major refurbishment in 2014 at a cost of more than £1.3m. It now hosts four NMR spectrometers including a 700 MHz equipped with a nitrogen-cooled cryoprobe for enhanced sensitivity.

This air-conditioned purpose-built laboratory also contains offices for personnel and additional computing provision.

Our particular expertise is in multinuclear NMR experiments over a wide temperature range.

Instruments

We currently have four spectrometers in the NMR facility.

Bruker AVANCE III HD 700 MHz

This spectrometer is equipped with a 24 position autosample changer and a triple-resonance nitrogen cooled CryoProbe Prodigy.

The probe is optimised for observation of ¹H/¹⁹F with enhanced sensitivity for ¹³C plus observation or decoupling of ¹⁵N. This probe is ideal for COSY, EXSY, NOESY, ROESY, HSQC, HMBC, TOCSY, DOSY and has a temperature range of 0 to +80 °C.

We also have a 5mm broadband multinuclear (BBO) probe for observation of nuclei in frequency range ¹⁰⁹Ag to ³¹P. This machine can decouple or observe 1H or 19F and has a temperature range of +/- 135 °C

Bruker AVANCE III HD 500 MHz

This is equipped with a 24 position autosample changer and a range of 5-10 mm probes covering virtually all NMR-active nuclei.

A triple-resonance probe on this machine allows us to observe the spectra of ¹³C and many other nuclei with simultaneous decoupling of ³¹P and ¹H.

This instrument is used by specially trained researchers for a wide range of studies in synthetic, mechanistic and catalytic chemistry, there being a special interest in dynamic systems.

Bruker AVANCE II 400 MHz

Equipped with a 60 position autosample changer and a 5mm auto-tuning broadband probe. This machine is automated using Topspin software and is available to all researchers on a walk-up basis.

Bruker AVANCE III 300 MHz

Equipped with a 60 position autosampler and a broadband multinuclear 5mm auto-tuning probe. This machine is automated to achieve high sample throughput and is available to all trained researchers on a walk-up basis.

Our staff

Dr Corinne Wills, NMR Officer
Dr Casey Dixon, Senior Analytical Technician (NMR)
Emeritus Professor William McFarlane, Emeritus Professor
Dr Keith Izod, Reader in Main Group Chemistry

Contact us

To request a quote, or ask us a question, you can complete our analytical services general enquiry form below.

If you’re a Newcastle University staff member or student, you can visit the internal Research and Analytical Services' intranet page.

General enquiry form

Nuclear magnetic resonance spectroscopy

Solid-state NMR