Staff Profile
Professor Jarka Glassey
Prof of Chemical Engineering Education
- Email: jarka.glassey@ncl.ac.uk
- Telephone: +44 (0) 191 208 7275
- Address: School of Engineering
Merz Court
Newcastle University
Newcastle upon Tyne
NE1 7RU
I am a Professor of Chemical Engineering Education in the School of Engineering at Newcastle University.
Roles and Responsibilities
- Immediate past Vice President Learned Society of IChemE
- Executive Vice President of the European Federation of Chemical Engineering
- Executive Vice President of the European Society of Biochemical Engineering Sciences
- UK representative of Working party on Education, EFCE
- Executive Member of the Education and Accreditation Forum of IChemE
- Editor in Chief, Education for Chemical Engineers
- Editor Journal of Applied Microbiology/Letters of Applied Microbiology
Area of expertise
- Bioprocess development
- Modelling (first principles, multivariate data analysis and hybrid modelling)
- Bioprocess optimisation
- Quality by design (QbD)
- Process analytical technologies (PAT)
- Chemical engineering education
- Immersive technologies (VR, AR, games, etc) in chemical engineering education
- Active learning
- Peer assisted learning
- Employability competencies
Qualifications
- Ing (1990) STU, Bratislava, Slovakia (equiv. to MEng Hons)
- PhD (1995) University of Newcastle upon Tyne
- Chartered Engineer (CEng, 2010)
Memberships
- 1994 IChemE
- 2006 MSfAM
Honours and Awards
- 2021 Fellow of Royal Academy of Engineering
- 2014 Principal Fellow HEA
- 2013 National Teaching Fellow
- 2010 VC Distinguished Teacher Award
- 2010 ExxonMobil Teaching Excellence Award
- 2010 Fellow IChemE
Languages
- Slovak - native
- Czech - native
- Hungarian, Russian - fluent
My research career as a biochemical engineer focused on delivering high-quality research at the interface of academia and industrial impact. My research outputs in the areas of bioprocess development, modelling, monitoring and control, Quality by design (QbD) and Process Analytical Technologies (PAT) have made significant contributions to R&D in the biopharmaceuticals, specialty chemicals and food & drink sectors both within and outside the UK.
My research approach is based on the fundamental understanding and monitoring of the biological processes using post genomic methodologies and combining it with engineering principles of scale-up and process intensification. Most recently my group is investigating the use of these methodologies in monoclonal antibody manufacture, cell gene therapy, viral production and ADC production. Specifically, my main interests stem from the area of advanced monitoring and control of processes and, over the years, I have developed and disseminated novel control strategies for the optimisation of recombinant protein production by integrating the physiological and engineering approaches.
Undergraduate Teaching
Biotechnology, Biochemical Engineering, Bioprocess Engineering, Design Project, Research project
Postgraduate Teaching
Control and Modelling of Bioprocesses
- Toyoda R, Russo Abegao F, Gill S, Glassey J. A Cross-Cultural Study on the Perception of the Use of Immersive Virtual Reality in Health and Safety Training for Professional Chemical Engineers. In: ChemEngDay 2020. 2021, Bradford, UK.
- Udeozor C, Russo Abegão F, Glassey J. An Evaluation of the Relationship between Perceptions and Performance of Students in a Serious Game. Journal of Educational Computing Research 2022, 60(2), 322-351.
- Udezor C, Russo Abegão F, Glassey J. Behaviour and Solution Patterns in Chemical Engineering Education Game Log Data. In: 15th European Conference on Games Based Learning. 2021, Brighton, UK: ECGBL.
- Emerson J, Glassey J. Bioprocess monitoring and control: challenges in cell and gene therapy. Current Opinion in Chemical Engineering 2021, 34, 100722.
- van Gerven T, Dumin M, Dominguez Alfaro J, Solmaz S, Santos P, Smets I, Bernaerts K, van Puyvelde P, Nasser R, van Loenen S, Adriaensen K, Haelterman K, Arztmann M, Hu Y, Gallagher T, Hornstra L, Slof B, Wouters P, Kester L, Croitoru N, Fornos S, Cermak-Sassenrath D, Udeozor C, Toyoda R, Russo Abegão F, Glassey J, Chan P, Guilpain G, Dubois J, Garcia Fracaro S, Wilk M, Tehreem Y, Pfeiffer T. Demonstration of Immersive Tools for Chemical Engineering Training. In: 13th European Congress of Chemical Engineering and 6th European Congress of Applied Biotechnology. 2021, Virtual Event: ECCE-ECAB.
- Toyoda R, Russo Abegão F, Gill S, Glassey J. Drivers of Immersive Reality Adoption Intention: A Multi-Group Analysis in Chemical Industry Settings. Virtual Reality 2021, Epub ahead of print.
- Bianchini LF, da Silva Ramos RCP, de Oliveira NS, de Paula RC, Rosa RT, Glassey J, Rosa EAR. Drug biotransformation process favored by fungal biofilms formed on a proposed fixed bed-airlift hybrid reactor. Journal of Chemical Technology and Biotechnology 2021, 96(4), 999-1006.
- Udeozor C, Russo Abegão F, Glassey J. Exploring Log Data for Behaviour and Solution Patter Analysis in a Serious Game. In: Bakan, U, ed. Gamification and Social Networks in Education. London: MacroWorld Ltd, 2021, pp.209-227.
- Udeozor C, Toyoda R, Russo Abegão F, Glassey J. Perceptions of the Use of Virtual Reality Games for Chemical Engineering Education and Professional Training. Higher Education Pedagogies 2021, 6(1), 175-194.
- Udeozor C, Russo Abegão F, Glassey J. Relationship Between Perceptions and Experiences on the Performance of Students in a Serious Game. In: 7th International Conference of the Immersive Learning Research Network. 2021.
- Garcia Fracaro S, Chan P, Gallagher T, Tehreem Y, Toyoda R, Bernaerts K, Glassey J, Pfeiffer T, Slof B, Wachsmuth S, Wilk M. Towards design guidelines for virtual reality training for the chemical industry. Education for Chemical Engineers 2021, 36, 12-23.
- Chan P, Guilpain G, Dubois J, Toyoda R, Russo Abegão F, Glassey J, Gallagher T, Kester L, Bernaerts K, van Gerven T. VR LaboSafe Game: A Virtual Reality Training Game for Chemical Engineering Laboratory Safety. In: 13th European Congress of Chemical Engineering and 6th European Congress of Applied Biotechnology. 2021, Virtual: IEEE.
- Udeozor C, Russo Abegão F, Glassey J. Evaluation of the Use of a Serious Game for Chemical Engineering Education. In: 14th European Conference in Games Based Learning (ECGBL 2020). 2020, Brighton, UK.
- Emerson J, Kara B, Glassey J. Multivariate data analysis in cell gene therapy manufacturing. Biotechnology Advances 2020, 45, 107637.
- Toyoda R, Russo Abegao F, Gill S, Glassey J. Perceptions of Professional Chemical Engineers Toward Immersive Virtual Reality in Health and Safety Training. In: The 8th European Conference on Education. 2020, London, UK (Online): The International Academic Forum (IAFOR).
- Fernandez Rivas D, Boffito DC, Faria-Albanese J, Glassey J, Afraz N, Akse H, Boodhoo KVK, Bos R, Cantin J, (Emily) Chiang YW, Commenge J-M, Dubois J-L, Galli F, de Mussy JPG, Harmsen J, Kalra S, Keil FJ, Morales-Menendez R, Navarro-Brull FJ, Noel T, Ogden K, Patience GS, Reay D, Santos RM, Smith-Schoettker A, Stankiewicz AI, van den Berg H, van Gerven T, van Gestel J, van der Stelt M, van de Ven M, Weber RS. Process intensification education contributes to sustainable development goals. Part 1. Education for Chemical Engineers 2020, 32, 1-14.
- Fernandez Rivas D, Boffito DC, Faria-Albanese J, Glassey J, Afraz N, Akse H, Boodhoo KVK, Bos R, Cantin J, Chiang YW, Commenge JM, Dubois JL, Galli F, de Mussy JPG, Harmsen J, Kalra S, Keil FJ, Morales-Menendez R, Navarro-Brull FJ, Noel T, Ogden K, Patience GS, Reay D. Process Intensification Education Contributes to Sustainable Development Goals. Part 2. Education for Chemical Engineers 2020, 32, 15-24.
- Karlberg M, de Souza JV, Fan L, Kizhedath A, Bronowska AK, Glassey J. Qsar implementation for hic retention time prediction of mabs using fab structure: A comparison between structural representations. International Journal of Molecular Sciences 2020, 21(21), 8037.
- Glassey J, Magalhaes FD. Virtual labs – love them or hate them, they are likely to be used more in the future. Education for Chemical Engineers 2020, 33, 76-77.
- Kizhedath A, Wilkinson S, Glassey J. Assessment of hepatotoxicity and dermal toxicity of butyl paraben and methyl paraben using HepG2 and HDFn in vitro models. Toxicology in Vitro 2019, 55, 108-115.
- Kizhedath A, Karlberg M, Glassey J. Cross-Interaction Chromatography-Based QSAR Model for Early-Stage Screening to Facilitate Enhanced Developability of Monoclonal Antibody Therapeutics. Biotechnology Journal 2019, 14(8), 1800696.
- Miguel CV, Moreira C, Alves MA, Campos JBLM, Glassey J, Schaer E, Kockmann N, Porjazoska Kujundziski A, Polakovic M, Madeira LM. Developing a framework for assessing teaching effectiveness in higher education. Education for Chemical Engineers 2019, 29, 21-28.
- Glassey J, Russo Abegão F, Gill S. Development of Academics Educating Future Generations of Chemical Engineers. In: The 12th European Congress of Chemical Engineering. 2019, Florence, Italy.
- Rosa EAR, Bianchini LF, da Silva Ramos RCP, Arantes AB, da Silva RF, Glassey J. Hydrodynamics of split-rectangle-internal loop airlift bioreactor with variations in riser and downcomer cross-sectional areas based on the golden ratio. Journal of Chemical Technology & Biotechnology 2019, 94(4), 1323-1329.
- Goldrick S, Sandner V, Cheeks M, Turner R, Farid SS, McCreath G, Glassey J. Multivariate Data Analysis Methodology to Solve Data Challenges Related to Scale-Up Model Validation and Missing Data on a Mirco-Bioreactor System. Biotechnology Journal 2019, 15(3), 1800684.
- Sandner V, Pybus LP, McCreath G, Glassey J. Scale-Down Model Development in ambr systems: An Industrial Perspective. Biotechnology Journal 2019, 14(4), 1700766.
- Glassey J. Tools for sharing with community - New article type in Education for Chemical Engineers. Education for Chemical Engineers 2019, 28, 66.
- Guerra A, von Stosch M, Glassey J. Toward biotherapeutic product real-time quality monitoring. Critical Reviews in Biotechnology 2019, 39(3), 289-305.
- Barone A, Glassey J, Montague G. Towards Online Near-Infrared Spectroscopy to Optimise Food Product Mixing. Journal of Food Engineering 2019, 263, 227-236.
- Russo-Abegao F, Glassey J. Advanced Chemical Engineering Professional Skills - Do We Teach Them Effectively?. In: 7th International Symposium of Engineering Education. 2018, University College London, London, UK.
- Karlberg M, von Stosch M, Glassey J. Exploiting mAb structure characteristics for a directed QbD implementation in early process development. Critical Reviews in Biotechnology 2018, 38(6), 957-970.
- Guerra AC, Glassey J. Machine learning in biopharmaceutical manufacturing. European Pharmaceutical Review 2018, 23(4), 62-65.
- Kizhedath A, Wilkinson S, Glassey J. Applicability of predictive toxicology methods for monoclonal antibody therapeutics: status Quo and scope. Archives of Toxicology 2017, 91(4), 1595-1612.
- Glassey J, Barone A, Montague GA, Sabou V. Case Studies in Modelling, Control in Food Processes. In: Hitzmann B, ed. Measurement, Modeling and Automation in Advanced Food Processing. Springer Science and Business Media Deutschland GmbH, 2017, pp.93-120.
- Glassey J, Abegão FR. E-assessment and tailored feedback - are they contributing to the effectiveness of chemical engineering education?. In: 7th World Engineering Education Forum. 2017, Kuala Lumpur, Malaysia.
- Glassey J, Russo Abegao F. E-assessment and tailored feedback - Are they contributing to the effectiveness of chemical engineering education?. In: 2017 7th World Engineering Education Forum, WEEF 2017- In Conjunction with: 7th Regional Conference on Engineering Education and Research in Higher Education 2017, RCEE and RHEd 2017, 1st International STEAM Education Conference, STEAMEC 2018. 2017, Kuala Lampur, Malaysia: IEEE.
- Ferreira GNM, Glassey J. Editorial: The European Symposium on Biochemical Engineering Sciences, Dublin 2016. Biotechnology Journal 2017, 12(7).
- Elrazak AER, Ward AC, Glassey J. The effect of inorganic salts on bacterial omega-3 pufa production. Preparative Biochemistry and Biotechnology 2017, 47(3), 291-298.
- Kizhedath A, Glassey J. The importance of critical quality attributes in Quality by Design for rapid bioprocess development strategies. European Pharmaceutical Review 2017, 22(6), 48-50.
- Glassey J, Kockmann N, Meshko V, Porjazoska Kujundziski A, Polakovic M, Madeira LM, Schaer E. iTeach: Evaluation of Teaching Efficiency in Chemical Engineering. Chemie-Ingenieur-Technik 2016, 88(9), 1226-.
- Glassey J, Kockmann N, Meshko V, Porjazoska Kujundziski A, Polakovic M, Madeira LM, Schaer E. Teaching efficiency in chemical engineering. In: 22nd International Congress of Chemical and Process Engineering (CHISA 2016) and 19th Conference on Process Integration, Modelling and Optimisation for Energy Saving and Pollution Reduction (PRES 2016). 2016, Prague, Czech Republic: Czech Society of Chemical Engineering.
- Haile S, Glassey J. Teaching of sustainability: Higher education (HE) case studies. In: Civil and Environmental Engineering: Concepts, Methodologies, Tools, and Applications. IGI Global, 2016, pp.1128-1139.
- Ndlovu TM, Ward AC, Glassey J, Eskildsen J, Akay G. Bioprocess intensification of antibiotic production by Streptomyces coelicolor A3(2) in micro-porous culture. Materials Science and Engineering: C 2015, 49, 799-806.
- Ndlovu TM, Ward AC, Glassey J, Eskildsen J, Akay G. Bioprocess intensification of antibiotic production by Streptomyces coelicolor A3(2) in micro-porous culture. Materials Science and Engineering C: Materials for Biological Applications 2015, 49, 799-806.
- Green A, Glassey J. Multivariate analysis of the effect of operating conditions on hybridoma cell metabolism and glycosylation of produced antibody. Journal of Chemical Technology and Biotechnology 2015, 90(2), 303-313.
- Hitzmann B, Hauselmann R, Niemoeller A, Sangi D, Traenkle J, Glassey J. Process analytical technologies in food industry - challenges and benefits: A status report and recommendations. Biotechnology Journal 2015, 10(8), 1095-1100.
- Glassey J, Ward AC. Solid state fermentation. In: Bora N; Dodd C; Desmasures N, ed. Diversity, Dynamics and Functional Role of Actinomycetes on European Smear Ripened Cheeses. Cham: Springer International Publishing, 2015, pp.217-225.
- Glassey J. Data Management Systems. In: O’Donnell CP; Fagan, C; Cullen, PJ, ed. Process Analytical Technology for the Food Industry. New York: Springer, 2014, pp.61-71.
- von Stosch M, Davy S, Francois K, Galvanauskas V, Hamelink JM, Luebbert A, Mayer M, Oliveira R, O'Kennedy R, Rice P, Glassey J. Hybrid modeling for quality by design and PAT - benefits and challenges of applications in biopharmaceutical industry. Biotechnology Journal 2014, 9(6), 719-726.
- Glassey J, Ottens M. Industrial biotechnology - Technologies and methods for rapid process development. Biotechnology Journal 2014, 9(6), 711-712.
- Glassey J. Industrialists - Listen up!. The Chemical Engineer 2014, (880), 34-36.
- El Razak AA, Ward AC, Glassey J. Process development of eicosapentaenoic acid production. Biochemical Engineering Journal 2014, 82, 53-62.
- Abd El Razak A, Ward AC, Glassey J. Screening of Marine Bacterial Producers of Polyunsaturated Fatty Acids and Optimisation of Production. Microbial Ecology 2014, 67(2), 454-464.
- Haile S, Glassey J. Teaching of sustainability: Higher education (HE) case studies. In: Handbook of Research on Pedagogical Innovations for Sustainable Development. IGI Global, 2014, pp.398-409.
- Glassey J, Novakovic K, Parr M. Enquiry based learning in chemical engineering curriculum supported by computer aided delivery. Education for Chemical Engineers 2013, 8(3), e87-e93.
- Glassey J. Multivariate Data Analysis for Advancing the Interpretation of Bioprocess Measurement and Monitoring Data. In: Measurement, Monitoring, Modelling and Control of Bioprocesses. Berlin: Springer-Verlag, 2013, pp.167-191.
- Glassey J. Peer assisted instruction and VLE in enquiry based learning in chemical engineering. In: 2nd Experiment@ International Conference (Exp.At'13). 2013, Coimbra, Portugal: IEEE.
- Abd Elrazak A, Ward AC, Glassey J. Polyunsaturated fatty acid production by marine bacteria. Bioprocess and Biosystems Engineering 2013, 36(11), 1641-1652.
- Abd Elrazak A, Ward AC, Glassey J. Response surface methodology for optimising the culture conditions for eicosapentaenoic acid production by marine bacteria. Journal of Industrial Microbiology & Biotechnology 2013, 40(5), 477-487.
- Rajarajan N, Ward AC, Burgess JG, Glassey J. Use of physiological information and process optimisation enhances production of extracellular nuclease by a marine strain of Bacillus licheniformis. Bioresource Technology 2013, 130, 552-558.
- Novakovic K, Parr M, Glassey J. Computer aided delivery of case-based learning activities in EBL within chemical engineering curriculum. Computer Aided Chemical Engineering 2012, 30, 1412-1416.
- Novakovic K, Parr M, Glassey J. Computer aided delivery of case-based learning activities in EBL within chemical engineering curriculum. In: 22 EUROPEAN SYMPOSIUM ON COMPUTER AIDED PROCESS ENGINEERING. 2012, SARA BURGERHARTSTRAAT 25, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS: ELSEVIER SCIENCE BV.
- Carrondo MJT, Alves PM, Carinhas N, Glassey J, Hesse F, Merten OW, Micheletti M, Noll T, Oliveira R, Reichl U, Staby A, Teixeira AP, Weichert H, Mandenius CF. How can measurement, monitoring, modeling and control advance cell culture in industrial biotechnology?. Biotechnology Journal 2012, 7(12), 1522-1529.
- Glassey J, Hopkins C, Joyce TJ. More ways than one: finding multiple ways to enhance the retention of students in their first year of two UK engineering degree programmes. Widening Participation and Lifelong Learning 2012, 14, 128-145.
- Luttmann R, Bracewell DG, Cornelissen C, Gernaey KV, Glassey J, Hass VC, Kaiser C, Lindström IM, Preusse C, Striedner G, Mandenius CM. Soft Sensors in Bioprocessing: A Status Report and Recommendations. Biotechnology Journal 2012, 7(8), 1040-1048.
- Glassey J, Haile SM. Sustainability in chemical engineering curriculum. International Journal of Sustainability in Higher Education 2012, 13(4), 354-364.
- Glassey J. Driving best practice in education. The Chemical Engineer 2011, (August), 3.
- Glassey J, Gernaey KV, Clemens C, Schulz TW, Oliveira R, Striedner G, Mandenius CF. Process analytical technology (PAT) for biopharmaceuticals. Biotechnology Journal 2011, 6(4), 369-377.
- Glassey J. Self-reflection and peer assessment – a way to effectively develop autonomous learners in HE?. In: Assessment in HE. 2011, Carlisle, UK.
- Gao Y, Kipling K, Glassey J, Willis M, Montague G, Zhou YH, Titchener-Hooker NJ. Application of Agent-Based System for Bioprocess Description and Process Improvement. Biotechnology Progress 2010, 26(3), 706-716.
- Glassey J. PAT methodologies in early process development. In: ESBES: EFB Section on Biochemical Engineering Science. 2010, Bologna, Italy.
- Abd El-Razak A, Glassey J. Process development for PUFA production using marine bacteria. In: ESBES: EFB Section on Biochemical Engineering Science. 2010, Bologna, Italy.
- Bracewell D, Gernaey KV, Glassey J, Hass VC, Heinzle E, Mandenius CF, Olsson IM, Racher A, Staby A, Titchener-Hooker N. Report and recommendation of a workshop on education and training for measurement, monitoring, modelling and control ((MC)-C-3) in biochemical engineering. Biotechnology Journal 2010, 5(4), 359-367.
- Glassey J. Sustainability: words or do we really teach the engineers effectively?. In: ISEE Educating Engineers for a Changing World. 2010, Cork, Ireland.
- Dawes N, Glassey J. Normalisation of multicondition cDNA macroarray data. Comparative and Functional Genomics 2007, 2007, Article ID 90578 (12 pages).
- Mohan P, Glassey J, Montague G. Pharmaceutical and Biotechnology - Manufacturing Lifecycle Analysis. McGraw Hill, 2005. In Press.
- Montague GA, Glassey J, Willis MJ. French fry quality improvement using advanced control techniques. Journal of Food Engineering 2003, 57(4), 357-365.
- Lau S, Willis MJ, Montague GA, Glassey J. Predictive scheduling of a bioprocess plant. In: Proceedings of the IASTED International Conference on Modelling, Simulation and Optimatization. 2003, Banff, Alberta, Canada: IASTED.
- Jha PP, Glassey J, Montague GA, Mohan P. Product cost management structures: a review and neural network modelling. Australasian Journal of Information Systems 2003, 11(1), 76-91.
- Glassey J, Cunha C, Ranjan A, Montague G. Addressing issues in bioprocess monitoring and control. In: Proceedings of the American Control Conference. 2002, Anchorage, Alaska.
- Cunha CCF, Glassey J, Montague GA, Albert S, Mohan P. An assessment of seed quality and its influence on productivity estimation in an industrial antibiotic fermentation. Biotechnology and Bioengineering 2002, 78(6), 658-669.
- Lennox B, Kipling K, Glassey J, Montague G, Willis M, Hiden H. Automated production support for the bioprocess industry. Biotechnology Progress 2002, 18(2), 269-275.
- Ranjan A, Glassey J, Montague G, Mohan P. From process experts to a real-time knowledge-based system. Expert Systems 2002, 19(2), 69-79.
- Glassey J, Montague G, Mohan P. Issues in the development of an industrial bioprocess advisory system. Trends in Biotechnology 2000, 18(4), 136-141.
- Ignova M, Montague GA, Ward AC, Glassey J. Fermentation seed quality analysis with self-organising neural networks. Biotechnology and Bioengineering 1999, 64(1), 82-91.
- Warnes MR, Glassey J, Montague GA, Kara B. Application of radial basis function and feedforward artificial neural networks to the Escherichia coli fermentation process. NEUROCOMPUTING 1998, 20(1-3), 67-82.
- J. Glassey,M. Ignova,A. C. Ward,G. A. Montague,A. J. Morris. Bioprocess supervision: Neural networks and knowledge based systems. Journal of Biotechnology 1997, 52(3), 201-205.
- Ignova M, Glassey J, Ward AC, Montague GA. Multivariate statistical methods in bioprocess fault detection and performance forecasting. TRANSACTIONS OF THE INSTITUTE OF MEASUREMENT AND CONTROL 1997, 19(5), 271-279.
- J. Glassey,G. A. Montague,A. C. Ward,B. V. Kara. Artificial Neural-Network-Based Experimental-Design Procedures for Enhancing Fermentation Development. Biotechnology and Bioengineering 1994, 44(4), 397-405.
- GLASSEY J, MONTAGUE GA, WARD AC, KARA BV. ARTIFICIAL NEURAL-NETWORK-BASED EXPERIMENTAL-DESIGN PROCEDURES FOR ENHANCING FERMENTATION DEVELOPMENT. BIOTECHNOLOGY AND BIOENGINEERING 1994, 44(4), 397-405.
- J. Glassey,G. A. Montague,A. C. Ward,B. V. Kara. Enhanced Supervision of Recombinant Escherichia-Coli Fermentations Via Artificial Neural Networks. Process Biochemistry 1994, 29(5), 387-398.