Staff Profile
Dr Jinju Chen
Senior Lecturer in Biointerface Engineering
- Email: jinju.chen@ncl.ac.uk
- Telephone: +44 (0) 191 208 5434
- Fax: +44(0) 191 208 8600
- Personal Website: http://www.staff.ncl.ac.uk/jinju.chen/
- Address: School of Engineering
Room M.2, Stephenson Building
Newcastle University
Newcastle Upon Tyne
NE1 7RU
Background
I am a Senior Lecturer (Equivalent to Associate Professor in USA) in Engineering. I currently leads a team of 9 researchers. Since 2016, her research group consists of 9-12 active researchers.
At Newcastle University, I have an established and growing international reputation in research as is evidenced by refereed journal papers (H-index=29), research income (£7.8M in total with £2.21M as PI from various funding agencies) and a range of external recognition from editorial roles to keynote/ invited conference talks. I have published over 70 refereed journal papers with a focus on top journals in computational modelling, bioengineering and materials engineering, including PLOS Computational Biology, ACS Applied Materials & Interfaces, Acta biomaterialia, Advanced Functional Materials, Applied Materials Today, npj Biofilms and Microbiomes.
I am Principal Editor of Journal of Materials Research (Springer Nature) and Editorial Board Member of Scientific Reports (Nature Publishing Group) . Her research is mainly funded by EPSRC with further funding from MRC, BBSRC and The Royal Society. She regularly reviews proposals for both RCUK and overseas research councils (e.g. Singapore, Isreal, France, Czech). She also examines PhD thesis nationally and internationally. She also sits in EPSRC Healthcare Technology panel and UKRI COVID panel. She is member EPSRC Peer Review College. Gained special Recognition in 2021 for my significant contribution (top 6% of EPSRC Peer Review College members) to EPSRC Peer Review.
I joined Newcastle as a lecturer in Sept. 2011. Shortly after that, I was invited to visit NTU (Singapore) to lead a project on computational cell mechanics which led to a paper published in Journal of Biomechanics. She resumed her teaching post at School of Mechanical & System Engineering in Jan 2012. She has 92 publications (73 journal papers, 2 bookchapters, 17 conference proceeding papers), with H-index of 29 and total citations exceeding 2,400 (googlescholar). In recent years, I have often been invited to give a keynote/invited talks on Biomechanics, Nanobiomechanics, antibiofilm surfaces and computational modelling at international conferences.
After obtaining my BEng, I moved to Newcastle to do PhD sponsored by various scholarships. Under the supervision of Prof. S.J. Bull (FREng), I completed Ph.D thesis within 2 years and 9 months in School of Chemical Engineering & Advanced Materials at Newcastle University. My PhD work involves mathematical modelling, computational modelling (FEM) and experimental characterisations of thin film materials. My PhD work has led to 8 first-authored journal papers and 3 first-authored conference papers. Then I worked as a Post-doc research associate at Newcastle (Nano Lab) & London (Cell & Tissue Engineering Lab, QMUL) to work on Multiscale Modelling of Functional Coatings and Multiscale Mechanobiology for Tissue Engineering, respectively. I was also an academic visitor at Max-Planck-Institut für Eisenforschung (Dusseldorf) to work on computational modelling crystal plasticity in collaboration with Prof. Dierk Raabe (Director).
I have worked on mechanics of advanced materials such as energy related materials, biomaterials, soft and hard biological tissues, finite element simulation, nanomechanics, nanotribology, and cell mechanics. I investigated the fracture and adhesion failure in ceramic coatings, creep in metallic coating, plastic deformation at submicro/nanoscale, viscoelastic behaviour of polymers, nonlinear elasticity in biomaterials etc. I am also very interested in fundamental nanoindentation mechanics, fracture mechanics and nonlinear elastic mechanics.
My current research covers : 1) cell and tissue mechanics (experimental and computational modelling); 2) mechanics of particles (including cells) using AFM; 3) rheology of hydrogels and biological materials ;4) antifouling surfaces; 5) nanofabrications and bio-inspired materials; 6) biofilm mechanics and modelling (continuum based model and particle based model); 7) multiscale mechanical testing of soft matter (incl. a new automated non-destructive testing approach developed in our team).
We welcome enthusiastic and talented researchers at all levels (UG to Post-doc researchers) to join us. We are also happy to sponsor the talented researchers (with PhD degree) to apply for external fellowship to be hosted at my lab.
External Postdoc Fellowships: Newton International Fellowships (open Jan-Mar); Marie Curie Individual Fellowships (Open Apr-Sep); EMBO Fellowships etc.
For the visiting students (UG, MSc or PhD), you need to be registered as occasional students and you need to have funding to cover the fee as occasional students.
ORCID
Congrats to the team! Our paper on ‘Nanostructured titanium surfaces exhibit recalcitrance towards Staphylococcus epidermidis biofilm formation’ made it to the top 100 most highly read materials science papers for Natures’ Scientific Reports journal in 2018, signifying its great value to the research community. https://www.nature.com/collections/fhacegjgia ; dated on 15 April 2019.
The research paper features the novel pocket-type surface nanostructures on titanium implant materials which enabled sustainable anti-biofilm effects. Such a pocket-like surface significantly outcompetes current pillar-based nanostructures in terms of anti-biofilm performance. The combined experimental and computational modelling approaches revealed new key mechanisms for antibiofilm characteristics of these structured surfaces. Such a chemical-free antibiofilm surface has the potential to tackle the antimicrobial resistance issues.
Read the paper here: https://www.nature.com/articles/s41598-018-19484-x
DOI: 10.1038/s41598-018-19484-x
Recent papers accepted in Biophysics, Biomechanics or structured surfaces related aspects:
Y Xia, PG Jayathilake, B Li, P Zuliani, D Deehan, J Longyear, P Stoodley, J. Chen. Coupled CFD-DEM modelling to predict how EPS affects bacterial biofilm deformation, recovery and detachment under flow conditions. Biotechnology and Bioengineering, accepted on 14 May, 2022.
SMA-based Soft Actuators with Electrically Responsive and Photoresponsive Deformations Applied in Soft Robots. Sensors and Actuators: A. Physical. accepted on 25 march 2022.
Slippery Liquid-Like Solid Surfaces with Promising Antibiofilm Performance in both Static and Flow Conditions. Y Zhu, G McHale, J Dawson, S Armstrong, G Wells, R Han, H Liu, W Vollmer, P Stoodley, NS Jakubovics, J. Chen. ACS Applied Materials & Interfaces, 2022, published online on 31 Jan 2022.
Thermal Diodes Based on Fractal Structures with Tunable Thermal Threshold, Tian Li,Weitao Jiang,Yue Zhang,Baotong Li,Lanlan Wang,Dong Niu,Hongzhong Liu,Lei Yin,Yongsheng Shi,Bangdao Chen,Jinju Chen,Xiaokang Liu,Donglin Peng, Advanced Functional Materials, published on 23 Dec 2021.
Crawling-Jumping Synergic Bioinspired robots Harnessing Electroactive Bistable Actuators by Adjusting Mechanical Response and Forces.Dachao Li, Dong Niu, Guoyong Ye, Biao Lei,JieHan, Weitao Jiang, Feng Luo, Jinju Chen, Hongzhong Liu,Bingheng Lu. Applied Materials Today, accepted on 8 June. 2021
Anti-wetting and anti-fouling performances of different lubricant-infused slippery surfaces, accepted in Langmuir, accepted on 20 Oct. 2020.
How Does Lubricant Viscosity Affect the Wear Behaviour of VitE-XLPE Articulated Against CoCr, accepted 25 Aug. 2020.
Intergrated Shape Memory Alloys Soft Actuators with Periodic and Inhomogeneous Deformations by Modulating Elastic Tendon Structures, Dachao Li; Dong Niu; Guoyong Ye; Biao Lei; Weitao Jiang; Feng Luo; Jinju Chen; Xin Li; Shaoxing Qu; Hongzhong Liu. ADVANCED ENGINEERING MATERIALS,DOI: 10.1002/adem.202000640, Sept. 2020
Bacterial nanotubes mediate bacterial growth on periodic nano-pillars, Yunyi Cao, Saikat Jana, Leon Bowen, Hongzhong Liu, Nicholas S. Jakubovics and Jinju Chen, Soft Matter, accepted on 20 July 2020.
Nonlinear rheological characteristics of single species bacterial biofilms , npj Biofilms and Microbiomes, npj Biofilms and Microbiomes volume 6, Article number: 19 (2020).
Muco-ciliary clearance: A review of modelling techniques, accepted on 15 Dec. 2019
NUFEB: A Massively Parallel Simulator for Individual-based Modelling of Microbial Communities, PLOS Computational Biology, accepted on 30 Oct. 2019.
Hierarchical rose-petal surfaces delay the early-stage bacterial biofilm growth, Langmuir, accepted on 21 Oct. 2019. DOI: 10.1021/acs.langmuir.9b02367
Modelling bacterial twitching in fluid flows: a CFD-DEM approach, Scientific Reports, accepted on 25 Sept. 2019,
Individual based model links thermodynamics, chemical speciation and environmental conditions to microbial growth, Valentina Gogulancea, Rebeca Gonzalez-Cabaleiro, Bowen Li, Denis Taniguchi, Pahala Gedara Jayathilake, Jinju Chen, Darren Wilkinson, David Swailes, Andrew Stephen McGough, Paolo Zuliani, Irina D Ofiteru, Thomas Curtis, Frontiers in Microbiology, accepted on 29 July 2019. Front. Microbiol. | doi: 10.3389/fmicb.2019.01871
Regulating, measuring and modelling the viscoelasticity of bacterial biofilms. Samuel Charlton, Michael White, Saikat Jana, Lucy Eland, Pahala Jayathilake, J. Burgess, Jinju Chen, Anil Wipat, and Thomas Curtis, Journal of Bacteriology, accepted on 5 June. 2019.
Formation of highly ordered micro fillers in polymeric matrix by electro-field-assisted aligning. Zhang Y, Zheng X, Jiang W, Han J, Pu J, Wang L, Lei B, Chen B, Shi Y, Yin L, Liu H, Luo F, Liu X, Chen J. RSC Advances 2019, 9(27), 15238-15245.
Mechanical interactions between bacteria and hydrogels, Nehir Kandemir, Waldmar Vollmer , Nick akubovics, Jinju Chen, Scientific Reports, accepted on 4 July 2018.
Finite Element Modelling of Nanoindentation Response of Elastic Fibre-Matrix Composites, Pengfei Duan, Yuqing Xia, Steve Bull and Jinju Chen; Journal of Materials Research, accepted on 26 June, 2018 ;
Modelling the nanomechanical responses of biofilms grown on the indenter probe, Yuqing Xia, Pengfei Duan, and Jinju Chen; Processes, accepted on 19 June, 2018 .
An Asymmetrical Dual Coating on the Stent Prepared by Ultrasonic Atomization, Wang, Jingjing; Huang, Yuhua; Ren, Yuzhen; Du, Ruolin; Xi, Yadong; Yin, Tieying; Wang, Yazhou; Zhang, Dechuan; Chen, Jinju; Wang, Guixue, Journal of Biomedical Materials Research: Part B - Applied Biomaterials, accepted on 28 May, 2018.
How cell culture conditions affect the microstructure and nanomechanical properties of extracellular matrix formed by immortalized human mesenchymal stem cells: an experimental and modelling study,,Pengfei Duan, Ria Toumpaniari, Simon Partridge, Mark Birch, Paul G Genever, Steve J. Bull, Kenny W Dalgarno, Andrew W McCaskie, Jinju Chen, Materials Science and Engineering-C, accepted on 26-MAR-2018 DOI information: 10.1016/j.msec.2018.03.027
Synthesis of bioinspired Collagen/Alginate/Fibrin based hydrogels for soft tissue engineering, G.Montalbano, S.Toumpaniari, A.Popov, P.Duan, J.Chen, K.Dalgarno, W.E.Scott, A.M.Ferreira, Materials Science and Engineering-C, 91 (2018) 236-246, accepted on 26-April-2018Nanostructured titanium surfaces exhibit recalcitrance towards Staphylococcus epidermidis biofilm formation, Yunyi Cao, Bo Su, Subash Chinnaraj, Saikat Jana, Leon Bowen, Sam Charlton, Pengfei Duan, Nicholas S. Jakubovics , and Jinju Chen , accepted in Scientific reports, 27 Dec 2017. DOI: 10.1038/s41598-018-19484-x. the top 100 most highly read materials science papers for Natures’ Scientific Reports journal in 2018
Pahala Gedara Jayathilake, Saikat Jana, Steve Rushton, David Swailes, Ben Bridgens, Tom Curtis, Jinju Chen, Extracellular polymeric substance production and aggregated bacteria colonization influence the competition of microbes in biofilms, Frontiers in Microbiology, accepted on 12 sept 2017.
Pahala Gedara Jayathilake, Prashant Gupta, Bowen Li, Curtis Madsen, Oluwole Oyebamiji, Rebeca González-Cabaleiro, Steve Rushton, Ben Bridgens, David Swailes, Ben Allen, Steve McGough, Paolo Zuliani, Irina Dana Ofiteru, Darren Wilkinson, Jinju Chen, Tom Curtis, A Mechanistic Individual-based Model of Microbial Communities, PLoS ONE 12(8): e0181965. https://doi.org/10.1371/journal.pone.0181965. : among the top 10% most cited PLOS ONE papers published in 2017. By chief-editor on 20 Nov. 2019.
Dan Zou, Wei Wang, Daoxi Lei, Ying Yin, Fei Fang, Peng Ren, Jinju Chen, Tieying Yin, Bochu Wang, Guixue Wang, Yazhou Wang*. Kill two birds with one stone:Penetrate blood-brain barrier and enable anti-tumor and nerve repair in glioma by DOX-loaded monosialoganglioside micelles system" has been accepted for publication in "International Journal of Nanomedicine", 7 June 2017
Effects of elemene on inhibiting proliferation of vascular smooth muscle cells and promoting reendothelialization at the stent implantation site, Biomaterials Science, Wenjie Sun, Yuhua Huang, Tieying Yin, Jingjing Wang, Ruolin Du, Juhui Qiu, Yuan Zhang, Yazhou Wang, Jinju Chen, Guixue Wang , Biomaterials Science, 2017, 5, 1144 - 1155, doi: 10.1039/C7BM00190H
Hunt NC, Hallam D, Karimi A, Mellough CB, Chen J, Steel DHW, Lako M. 3D culture of human pluripotent stem cells in RGD-alginate hydrogel improves retinal tissue development. Acta Biomaterialia 2017, 49, 329-343
Topical Review
- Jinju Chen, Indentation based methods to assess fracture toughness for thin coatings, Journal of Physics D: Applied Physics (2012) 45 203001 doi:10.1088/0022-3727/45/20/203001
Invited papers
- Chen J. Nanobiomechanics of Living Cells: a review, Royal Society Interface Focus, 2014, 4: 20130055. http://dx.doi.org/10.1098/rsfs.2013.0055
- Chen J, Wright KE, Birch MA. Nanoscale viscoelastic properties and adhesion of polydimethylsiloxane for tissue engineering, Acta Mechanica Sinica, 2014, DOI 10.1007/s10409-014-0022-0.
- Chen J, Bull SJ. Approaches to investigate delamination and interfacial toughness in coated systems: an overview. Journal of Physics D: Applied Physics 2011,44 3 034001.
- Chen J, Bull SJ. On the factors affecting the critical indenter penetration for measurement of coating hardness. Vacuum 2009. ,83 6 911-920.
- Chen J, Bull SJ. Indentation fracture and toughness assessment for thin optical coatings on glass. Journal of Physics D: Applied Physics 2007, 40(18), 5401-5417.
Bookchapter
- Jinju Chen, A non-destructive approach to determine fracture toughness of coating: Nanoindentation tests and analysis, Chapter 3, pp123-178,in Thin Films and Coatings: Toughening and Toughness Characterisation, edited by Sam Zhang, published on July 29, 2015 by CRC Press
- Jinju Chen, Chapter 7: Thin film coatings and the biological interface , Thin Film Coatings for Biomaterials and Biomedical Applications; Woodhead Publishing Series in Biomaterials: Number 110, 143-164, edited by Prof. Hans Griesser, published on March 15, 2016.
Journal Editor
- Guest Editor for Thin Solid Films, 2014-2015,
- Guest Editor for Surface and Coatings Technology, 2016-2017
- Appointed as a Principal Editor of Journal of Materials Research (Feb 2016- )
- Guest Editor for Special Issue "Physics and Mechanics of Biofilms: Modelling and Experimental Characterizations" in Processes
Editorial Board
Editorial Board Member of Scientific Reports (Nature Publishing Group) in the topic of Biological Physics
International Journal of Nanomedicine and Nanotechnology
Conference chair/society chair
* Co-Chair of Symposium E - Organic and Biological Coatings of TACT 2017 (International Thin Films Conference), Taiwan, 15-18Oct, 2017
* Session chair for Soft matters & MD/ab initio applications, 9TH INTERNATIONAL CONFERENCE ON MATERIALS FOR ADVANCED TECHNOLOGIES, Singapore, June 2017
Appointed as Chairperson of Tyne & Wear Materials Society (2016- ), IOM3, UK.
· Chairing a session in Nanoindentation Conference at Newcastle 2010.
* Co-chair of Symposium of Mechanical properties of thin films (MPF), ThinFilms2014.
* Co-chair topical session in 42nd Intl. Conf. Metallurgical Coatings and Thin Films (ICMCTF), 20–24 April 2015, San Diego, United States.
* Co-chair topical session in 43rd Intl. Conf. Metallurgical Coatings and Thin Films (ICMCTF), 25–29 April 2016, San Diego, United States.
Conference organization committee
· Conference organizing committee for Nanoindentation Conference at Newcastle 2008.
* Conference organizing committee for the 7th International Conference on Technological Advances of Thin Films & Surface Coatings, China 2014 .
* Conference co-organizer for THINFILMS2016 (8th International Conference on Technological Advances of Thin Films & Surface Coatings) ,12th-15th July 2016, SINGAPORE
* 42nd, 43rd, 44th Intl. Conf. Metallurgical Coatings and Thin Films (ICMCTF), USA, 2015, 2016, 2017
*
Reviewer for international and national funding bodies
· Czech Republic Science Foundation* (2009-present), National Research Foundation (NRF) Singapore (2016-present), ANR ( French National Research Agency), (2016-present) , Israel Science Foundation (2020) , Cyprus Research Promotion Foundation (RPF) , 2018.
* EPSRC* (2013-present), BBSRC (2014-present)*, MRC (2015-present)*, Cancer Research UK (2017-present), Dunhill Medical Trust (2017-present). : * frequently
External Ph.D examiner for the following University
University of Liverpool (Jan 2022)
Anna University, India (2021)
University of Bristol (2019)
University of London Queen Mary (2019)
Nanyang Technological University, Singapore (2012, 2018, 2020)
University of Groningen, Netherlands (2016)
External Examiner of MPhil for University of Manchester (2017)
Reviewer for the chapters in the technical book proposals for
Wiley (2012-present)
Reviewer for Journals
Manuscript reviewer for Advanced Functional Materials, Nano Today, Molecular Pharmaceutics, ACS Applied Materials & Interfaces, Acta Biomaterialia, Medicinal Research Reviews, Nanotechnology, Journal of Physics: Condensed Matter, Biomedical Materials, Biomechanics and Modeling in Mechanobiology, Journal of the Mechanical Behavior of Biomedical Materials*, Journal of Materials Research*, J. Phys. D: Appl. Phys.*, Biomacromolecules, Water Research, Applied Microbiology, Experimental Mechanics*, Acta Mechanica Sinica, Crystal Growth & Design, Materials & Design, Journal of Materials Science, Materials Science and Engineering C*, Physical Chemistry Chemical Physics, International Journal of Non-Linear Mechanics; Applied Physics A, Thin Solid Films*, Surface Coating & Technology*, Materials Research Express , Journal of Alloys and Compounds, Semiconductor Science and Technology, Tribology International, Nanoscience and Nanotechnology Letters, Wear, npj Biofilms and Microbiomes, Royal Society Interface, Journal of Materials Science and Technology, PLOS one, IScience, Scientific Reports .
*: frequently
Invited presentations and seminars
Biomaterials, biophysics , biomechanics or cell mechanics
keynote talk: 6th International Conference of Theoretical and Applied Nanoscience and Nanotechnology (TANN’22), Canada.
Keynote talk: AFM & SPM Meeting 2022, UK
Keynote talk: International Conference IEEE 3M-NANO 2022, China
Invited talk: International Conference on Frontier Materials 2021” (ICFM) , China. postponed to 2022 due to COVID
Sept. 2019: ETH Zurich
June 2019: Invited speaker in Symposium M: Biomechanics in Human Diseases – Research and Applications and Symposium FF: Computational Advanced Material Science and Application at 10th International Conference on Materials for Advanced Technologies (ICMAT 2019), Singapore
Jan. 2019: University of Leeds; Southeast University; Shanghai Jiaotong University, East China University of Science and Technology.
Dec. 2018: Chinese Academy of Sciences, Nanjing Tech University, Southern University of Science and Technology, Shenzhen University, Beijing institute of chemical technology, Hainan University.
Sept. 2018: University of Tennessee, USA
Dec.2017: Xi'an Jiao Tong University, China
Dec.2017: South China Normal University, China
Dec.2017: Jinan University, China
Dec.2017: South China University of Technology, China
18 - 23 June 2017: 9th International Conference on Materials for Advanced Technologies (ICMAT 2017), Suntec, Singapore
April 2017: Montana State University, USA.
Jan 2017: Chongqing University , China
Dec 2016: Invited guest lectures on Finite element modelling for University of Chinese Academic Of Science
Dec 2016: Perking University (Beida), China
Dec 2016: Beihang University , China
Dec 2016: Tsinghua University, China
Nov 2016: National Physical Lab, UK
July 2016: National University of Singapore
July 2016: University of Malaya, Malaysia
July 2016: Nanyang Technological University, Singapore
March 2016: Symposium of Biointerfaces, Advanced Materials Conference, Newcastle, UK
Jan 2016: Chinese Academic of Science, Beijing,China
Jan 2016: Hohai University , China
Dec 2015: Xi'an Jiao Tong University, China
Dec 2015: Chinese Academic of Science, Qingdao,China
Dec 2015: Tongji University, China
March 2015: Keynote speaker @ 5th Annual International Conference on Advances in Biotechnology (BioTech 2015) , India, http://www.advbiotech.org/
•Oct 2015: University of Manchester,UK
•Dec 2014: Sun Yat-Sen University , China
•Dec 2014: Zhejiang University , China
•Dec 2014: South China University of Technology, China
•Dec 2014: Soochow University, China
•May 2014: Glasgow University, UK
•Apr 2014: Columbia University, USA
•Apr 2014: Montana State University, USA
•Nov 2013: Nanyang Technological University, Singapore
•Dec. 2012: Chinese Academy of Science, Institute of Mechanics, China.
•Dec. 2012: Beihang University, China.
•Dec. 2012: Beijing Institute of Technology, China
•Apr. 2012: University of Kentucky, USA
•Apr. 2012: University of California, San Diego, USA
•Dec. 2011: Nanyang Technological University, Singapore
•Dec. 2010: Peking University, Beijing, China.
•Dec. 2010: Beijing Institute of Technology, Beijing, China.
•Sept. 2010: University of Cambridge, UK
•Aug. 2010: Symposium of Chondrocyte Mechanics in 6th World Congress on Biomechanics, Singapore.
•Aug.2010: Nanyang Technological University, Singapore .
Nanomechanics, Fracture Mechanics and Interface Adhesion
Dec 2016: Technical Institute of Physics and Chemistry, Chinese Academic of Science,
*July 2016: THINFILMS2016, SINGAPORE
•Dec 2014: Guangdong University of Technology , China
•Jul 2014: 7th International Conference on Technological Advances of Thin Films & Surface Coatings, China
•May 2014: Glasgow University, UK
•Apr. 2014: 41st International Conference on Metallurgical Coatings and Thin Films (ICMCTF), San Diego, USA.
•Mar.2013: National Physical Laboratory, Institute of Physics (IOP) Tribology Group Conference.
•June 2011: Materials Today Virtual Conference: Characterization Techniques and Analysis.
•Dec. 2010: The University of Hong Kong, Hong Kong, China.
•Dec. 2010: Peking University, Beijing, China.
•Dec. 2010: Beijing Institute of Technology, Beijing, China.
•Aug. 2008: Loughborough University, UK.
•May 2008: Institute of Physics One–Day Seminar on Nanoindentation and Nanotribology, National Physical Laboratory,UK
•May 2008: Nanomechanical Labortary, Hysitron Inc., Minneapolis, USA.
•May 2008: University of South Carolina, USA.
Academic Visitor
Nanyang Technological University, Singapore.
Loughborough University, UK.
Max-Planck-Institut für Eisenforschung, Dusseldorf, Germany.
Conference presentations
I have made more than 30 presentations in international conferences such as MRS Fall meeting, MS&T conference, International Conference on Metallurgical Coatings and Thin Films (ICMCTF), Congress of the European Society of Biomechanics,Tissue and Cell Engineering Society (TCES), International Conference on Cell & Stem Cell Engineering (ICCE).
Recent awards (after 2007)
· European Society of Biomechanics (ESB) Travel Award 2010
· International Travel Grant (The Royal Society) 2010
· The following article has been selected as one of the highlights in the year of 2007 in J. Phys. D: J. Chen and S J Bull, Indentation fracture and toughness assessment for thin optical coatings on glass, J. Phys. D: Appl. Phys. 40 (2007) 5401-5417
Industry consultancy experience
Stress analysis, Hardness and wear analysis of Coatings, Fracture and delamination analysis.
Professional membership
Materials Research Society; Europe Society of Biomechanics; Tissue and Cell Engineering Society;
Institute of Physics
Research
Selected funded projects
2012-2013: Industrial consultancy project with Metalysis , Ltd (Co-I)
2013-2019: A New Frontier in Design: The Simulation of Open Engineered Biological Systems, one of the only five prestigious Frontier Awards (~£5.56 millions) funded by EPSRC (EP/K039083/1), strategic Co- investigator and team leader for the theme of Biomechanics and Flow within the project.
2013: Using nanomechanical testing and modelling to understand the biophysics of cell-hydrogel Interactions, funded by EPSRC, Principal Investigator (PI)
2014-2018: Multiscale modelling and characterisation of biofilms (SAgE DTA award, PI)
2014-2017: Biomechanics of bacteria (school DTA award, PI)
2014-2015: Designing a new cannula and injection system for subretinal injections,MRC Confidence in Concept (CiC) Fund, Co-I.
2015-2019: Biophysics of biofilms in wastewater treatment (DPT award, PI)
2016-2020: Computational modelling to study cell-materials interactions for tissue engineering, Newcastle-Singapore Studentship, PI)
June-July 2016: Newton Fund and British council travel award to attend Vietnam-UK Young Scientist Networking Conference on Biomedical Engineering. (PI)
2017-2020: The biophysics for bacteria-materials interactions, Research Excellence Academy PhD studentship, PI.
2017-2021: EPSRC Industrial CASE Award in partnership with P & G (PI)
2017-2018: EPSRC Partnering for GCRF: Develop chemical-free anti-biofilm surface (PI)
2017-2018: High performance computational & microfluidic models of complex biofilm dynamics, Oak Ridge National Lab ( Co-I)
2018-2020: Multiscale characterization of complex materials using a combination of atomic force microscopy and optical coherence tomography funded by EPSRC (EP/R025606/1), £487k, PI).
2018-2019: Investigate how the architectures of nanostructured surfaces affect bacterial adhesion and biofilm formation, Oak Ridge National Lab (PI).
2019: EPSRC Soft Mech feasibility grant: Characterising the microstructure and mechanical properties of cells (PI)
2018-2022: Experimental Cell Mechanics to Understand Disease progression, EPSRC DTP studentship (PI, EP/R51309X/1)
2019-2023: EPSRC DTP studentship ( PI, EP/N509528/1 )
2019-2023: Chinese Scholarship Council ( CSC) studentship plus Newcastle Univ ( PI)
2019-2020: BBRSC NBIC on marine biofilms (PI)
2020-2022: The Royal Society -Newton Mobility Grant (PI)
2020-2021: BBRSC NBIC on biofilm mechanics and modelling (PI)
2021-2022: BBRSC NBIC on preventing biofilm formation (PI)
2022-2025: EPSRC on novel antibiofilm surfaces (PI)
2022-2026: EPSRC CASE project funded by EPSRC and AkzoNobel. (PI)
EPSRC or BBSRC funded post-doctoral research associates:
Dr. Yasmine Ammar (Mar 2014-May 2015, PhD from Newcastle), now got a permanent job as data analyst and modeller in public section.
Dr. Jaya PAHALA GEDARA (Oct 2014- Feb 2019, PhD from NUS (Singapore), post-doc at NUS), Now at University of Oxford as a PDRA in Computational biology
Dr. Saikat Jana (Aug 2015-Aug 2019, PhD from Virgin Tech, post-doc at MIT, Glasgow), Now at University of Leeds as a PDRA in biophysics and biomechanics
Dr. P. Duan (Feb-March 2018, PhD from Newcastle), Now work in China
Dr. Nehir Kandemir (March 2018, Feb 2019-May 2019,PhD from Newcastle), Now work in ANSYS, Cambridge.
Dr. Ben Allen (2020), BBSRC funded senior PDRA: PhD from Newcastle
Dr. Yuqing Xia (2021-2022), BBSRC funded PDRA, PhD from Newcastle.
Current PhD students supervised as the lead supervisor:
Mr. Luo Ma (joined in Jan 2018)
Mr. John Exton (joined in Sept. 2018)
Mr. Yufeng Zhu (joined in Jan. 2019)
Mr. Jack Dawson (joined in Sept. 2019)
Mr. Rui Han (joined in Sept. 2019)
Mr. Sam Coaster ( joined in Sept 2021)
MPhil student:
Mr. Zeshen Wang (joined in Jan 2022)
PGR students completed: 8 PhDs and 1 MPhil
Mr. Yunyi Cao: completed MPhil in 2017.
Dr. Pengfei Duan (started in Jan 2014 , submitted draft thesis in Sept. 2017, successfully defended thesis in Nov 2017, PhD awarded in March 2018). Now he works as KTP scientist in a Chinese Research Institute.
Dr. Nehir Kandemir (joined in Sept.2014, draft thesis submitted in May 2018, successfully defended her PhD thesis in July 2018), PhD awarded in Nov 2018. PDRA in my group in 2019. Now secured a permanent job in ANSYS, UK.
Dr. Subash Chinnaraj (joined in Nov. 2014, draft thesis submitted in Nov, successfully defended PhD thesis in Dec 2018, Awarded in Feb. 2019). secured an industrial job in the UK.
Dr. Sam Charlton (joined in Sept.2015), successfully defended his PhD thesis on 7 Oct 2019. He just started PDRA job at ETH, Zurich, Switzerland.
Dr. James Hood successfully defended his PhD thesis on 26 Nov. 2019. He started a project engineer in a company in the UK from Oct 2019. PhD awarded in Feb. 2020. secured an industrial job in the UK.
Dr. Yunyi Cao successfully defended his PhD thesis on 5 March 2020. PhD awarded in April 2020. He has secured an industrial R&D post in China.
Dr. Wenjian Yang successfully defended his PhD thesis on 17 Dec 2020. He secured a tenure tracked Assistant professor position in a leading university in China.
Dr. Yuqing Xia successfully defended her PhD thesis on 6 April 2021.
Visiting academic fellows : Associate Prof. Y Wang (now full professor); Associate Prof. T Yin ( Jan 2017- July 2017) from China, Associate Professor Tianyu Zhang (Nov-Dec 2017) from USA. Dr. S. Elatriby (July 2015-Jan 2016)from Egypt.
Previous group members : Dr. S. Elatriby (July 2015-Jan 2016); Dr Yasmine Ammar (2014-2015, funded by EPSRC), Dr. P. Duan (Feb-March 2018, funded by EPSRC), Dr. Wenbo Wang (Jan 2015-July 2015)
Group news (2016-present):
Dr. Chen, Dr Phahala, Mr Chinnaraj all gave oral presentations at 43rd ICMCTF at San Diego in April 2016.
Mr Duan gave an oral presentation at ThinFilms2016, Singapore in July 2016.
Congratulations to yunyi Cao and pengfei Duan who have a joint paper published in Nanotechlology (IF=3.82) in 2016 .
Summer internship student Mieszko Jaskiewicz in my group, who works on microfluidics, was the overall Faculty prize winner (£300) at the recent ‘Celebrating Student Research Scholarships and Expeditions’ annual poster and presentations evening 2016.
Mr Yunyi Cao and Sam Charlton were the Tyne & Wear Materials Society (TWMS) (associated with IOM3) young person lecture competition 2017 winner (£100) and runner-up (£50).
Mr Yunyi Cao and Sam Charlton were the runner-up in PGR conference in 2017.
Ms Nehir Kandemir was the winner for TCES scholarship, awarded in April 2017.
Prof. Yin and Prof. Wang just had a joint paper with us accepted in Biomaterials Science in April 2017. Well done !
Dr. Chen, Ms Kandemir, Mr Charlton, Mr Cao all gave oral presentations at 44th ICMCTF at San Diego in April 2017.
Prof. Wang and Prof. Yin just had a joint paper with us accepted in "International Journal of Nanomedicine", 7 June 2017. Well done !
Dr Chen, Ms. Kandemir presented papers at MRS fall meeting at Boston 2017 .
Congratulations to Pengfei Duan who successfully defended his thesis in Nov 2017 ! Now he becomes Dr. Duan.
Mr. Y. Cao, Mr. Chinnaraj and other members within the group just had a joint paper accepted in Scientific reports in Dec 2017. Well done !
Mr Ma LUO and Mr Yunyi Cao were the Tyne & Wear Materials Society (TWMS) (associated with IOM3) young person lecture competition 2018 winner (£100) and runner-up (£50), respectively.
Dr. Duan has just published a paper in Materials Science & Engineering C in march 2018. Well done !
Ms Nehir Kandemir, Ms yuqing Xia, and Dr. Duan published a joint paper in MRS Advances in 2018. well done!
Mr. Yunyi Cao and Mr. Sam Charlton have won first prizes in their sessions in PGR conference in march 2018. Well done.
Dr. Duan and Miss Xia just had a joint paper accepted in Journal of Materials Research in June 2018. Well done !
Miss Xia and Dr. Duan and just had a joint paper accepted in Processes in June 2018. Well done !
Miss Nehir Kandemir just had a paper (which covers most of her PhD work) accepted in Scientific Reports (nature publishing group) in July 2018. Well done !
Miss Nehir Kandemir successfully defended her PhD viva on 19 July 2018. Well done !
Mr Subash Chinnaraj successfully defended his PhD viva on 20 Dec 2018 (just before Christmas holiday). Well done !
Mr. Sam Charlton (joined in Sept.2015), successfully defended his PhD thesis on 7 Oct 2019. Well done ! He just started PDRA job at ETH, Zurich, Switzerland.
Mr. John Exton was he Tyne & Wear Materials Society (TWMS) (associated with IOM3) young person lecture competition 2019 runner-up.
Mr Jack Dawson and Miss yuqing Xia were the Tyne & Wear Materials Society (TWMS) (associated with IOM3) young person lecture competition 2020 winner (£100) and runner-up (£50).
Mr John Exton and Mr. Ma Luo were the Tyne & Wear Materials Society (TWMS) (associated with IOM3) young person lecture competition 2021 winner (£100) and runner-up (£50).
Mr John Exton was the runner up for Northeast YPLC Regional Final (associated with IOM3) 2021.
Mr. Rui Han just had a paper accepted in JMR on 5 April 2021.
My Expertise
Biomechanics, Fracture mechanics, Adhesion evaluation, Nano/Micromechanics, Surface analysis, Finite element simulation, 3D modelling for biomedical images.
Applied Mathematical Modelling ( I was selected to participate International Mathematical Contest in Modelling when I was an undergraduate. I still have strong interest in mathematical modelling. If you share the same interest, please feel free to contact me. )
Research area
Nanomechanics : Nanoindentation; Nanotribology
Rheology and microfludics: rheology of soft materials and solutions, Microfluidic device and characterisation and its applications
Bacterial Adhesion and Biofilm Mechanics
Multiscale biomechanics in both experimental and modelling techniques,
The physics of biofilm formation
Develop methods to inhibit biofilm formation or destroy biofilms
Droplet dynamics
Finite Element Analysis: Biomechanics; Modelling deformation in advanced materials; Modelling Interfacial crack initiation and evolution
Mechanics of Biomaterials: Tissue engineered bone; Cell-matrix interaction; Cell mechanics; Hydrogel scaffold, Soft tissues mechanics
Thin Film Mechanics: Energy related coatings (Anode Coatings & Solar Control Coatings); Polymeric coatings; Hard coatings; MEMS
Other major research projects I've worked on
*A multiscale Modelling Approach to Engineering Functional Coatings (EPSRC Materials Modelling Consortium *Multiscale Mechanobiology for Tissue Engineering (EPSRC Platform Grant)
Opportunities
Postgraduate research students (Ph.D, MPhil and MRes), visiting research students, summer internship or visiting scientists (or fellows) are welcome to join my group. In the past two years, I have hosted excellent summer students (sponsored by various councils) from Brazil , Germany, Jordan, France and China.
Other projects include:
Biomechanics and Mechanotransduction (priority area in my group)
1. Nanofabrication and bio-inspired materials
2. Multiscale modelling of soft tissue mechanics
3. Multiscale modelling of biofilms
4. Cell-materials interactions
5. Mechanics of Advanced Biomaterials
6. Cell Mechanics and biophysics
Previous work in Thin Film Mechanics
1. Multiscale modelling of mechanics of functional coatings
2. Predict mechanical durability and performance of battery materials
3. Cracking and delamination of coatings
Teaching
Teaching & supervising
Semester 1
Mechanical Engineering professional Skills
Materials Science (practical)
Mechanics II
Computational modelling
Nanomaterials
Tutor of Stage 1 students
Semester 2
Design for industry
Applied Mechanics (Module leader)
Mechanical Engineering professional Skills
Engineering Mathematics with Applications
Nanomaterials
Tutor of Stage 1 students
Individual supervision for BEng and MSc students
Sem1 -Sem 2: Supervision of Team project for Design for Industry and MEng project
MSc, and BEng students in Mechanical Engineering and Bioengineering, as well as excellent internship students fully sponsored by different organizations.
I also host government (or research council, home University) sponsored visiting research fellows and research students with strong track of record.
Publications
- Xia Y, Jayathilake PG, Li B, Zuliani P, Deehan D, Longyear J, Stoodley P, Chen J. Coupled CFD-DEM modelling to predict how EPS affects bacterial biofilm deformation, recovery and detachment under flow conditions. Biotechnology and Bioengineering 2022. In Press.
- Zhang Z, Lei B, Zhao G, Ban Y, Da Z, Wang Y, Ye G, Chen J, Liu H. Distance and depth modulation of Talbot imaging via specified design of grating structure. Optics Express 2022, 30(7), 10239-10250.
- Luo M, Yang W, Cartwright TN, Higgins JMG, Chen J. Simultaneous Measurement of Single-Cell Mechanics and Cell-to-Materials Adhesion Using Fluidic Force Microscopy. Langmuir 2022, epub ahead of print.
- Zhu Y, McHale G, Dawson J, Armstrong S, Wells G, Han R, Liu H, Vollmer W, Stoodley P, Jakubovics NS, Chen J. Slippery Liquid-Like Solid Surfaces with Promising Antibiofilm Performance in both Static and Flow Conditions. ACS Applied Materials & Interfaces 2022, 14(5), 6307-6317.
- Niu D, Li D, Chen J, Zhang M, Lei B, Jiang W, Chen J, Liu H. SMA-based Soft Actuators with Electrically Responsive and Photoresponsive Deformations Applied in Soft Robots. Sensors and Actuators: A. Physical 2022, epub ahead of print.
- Han R, Chen J. A modified Sneddon model for the contact between conical indenters and spherical samples. Journal of Materials Research 2021, 36, 1762-1771.
- Xia Y, Jayathilake P, Li B, Zuliani P, Chen J. CFD-DEM modelling of biofilm streamer oscillations and their cohesive failure in fluid flow. Biotechnology and Bioengineering 2021, 118(2), 918-929.
- Li D, Niu D, Ye G, Lei B, Han J, Jiang W, Luo F, Chen J, Liu H, Lu B. Crawling-Jumping Synergic Bioinspired robots Harnessing Electroactive Bistable Actuators by Adjusting Mechanical Response and Forces. Applied Materials Today 2021, 24, 101091.
- Chinnaraj SB, Jayathilake PG, Dawson J, Ammar Y, Portoles J, Jakubovics NJ, Chen J. Modelling the combined effect of surface roughness and topography on bacterial attachment. Journal of Materials Science & Technology 2021, 81, 151-161.
- Yang W, Lacroix D, Tan lLP, Chen J. Revealing the nanoindentation response of a single cell using a 3D structural finite element model. Journal of Materials Research 2021, epub ahead of print.
- Li T, Jiang W, Zhang Y, Li B, Wang L, Niu G, Liu H, Yin L, Shi Y, Chen B, Chen J, Liu X, Peng D. Thermal Diodes Based on Fractal Structures with Tunable Thermal Threshold. Advanced Functional Materials 2021, Epub ahead of print.
- Cao Y, Jana S, Tan X, Bowen L, Zhu Y, Dawson J, Han R, Exton J, Liu H, McHale G, Jakubovics NS, Chen J. Antiwetting and Antifouling Performances of Different Lubricant-Infused Slippery Surfaces. Langmuir 2020, 36(45), 13396–13407.
- Cao Y, Jana S, Bowen L, Liu H, Jakubovics NS, Chen J. Bacterial nanotubes mediate bacterial growth on periodic nano-pillars. Soft Matter 2020, 16(32), 7613-7623.
- Kandemir G, Smith S, Chen J, Joyce TJ. How does lubricant viscosity affect the wear behaviour of VitE-XLPE articulated against CoCr?. Journal of the Mechanical Behavior of Biomedical Materials 2020, 112, 104067.
- Li D, Niu D, Ye G, Lei B, Jiang W, Luo F, Chen J, Li X, Qu S, Liu H. Intergrated Shape Memory Alloys Soft Actuators with Periodic and Inhomogeneous Deformations by Modulating Elastic Tendon Structures. Advanced Engineering Materials 2020, 22(12), 2000640.
- Vanaki SM, Holmes D, Saha S, Chen J, Brown RJ, Jayathilake PG. Muco-ciliary clearance: A review of modelling techniques. Journal of Biomechanics 2020, 99, 109578.
- Jana S, Charlton SGV, Eland LE, Burgess JG, Wipat A, Curtis TP, Chen J. Nonlinear rheological characteristics of single species bacterial biofilms. npj Biofilms and Microbiomes 2020, 6, 19.
- Wang J, Ren Y, Huang Y, Du R, Xi Y, Yin T, Wang Y, Zhang D, Chen J, Wang G. An Asymmetrical Dual Coating on the Stent Prepared by Ultrasonic Atomization. Journal of Biomedical Materials Research Part B: Applied Biomaterials 2019, 107(3), 825-837.
- Zhang Y, Zheng X, Jiang W, Han J, Pu J, Wang L, Lei B, Chen B, Shi Y, Yin L, Liu H, Luo F, Liu X, Chen J. Formation of highly ordered micro fillers in polymeric matrix by electro-field-assisted aligning. RSC Advances 2019, 9(27), 15238-15245.
- Cao Y, Jana S, Bowen L, Tan X, Liu H, Rostami N, Brown J, Jakubovics NJ, Chen J. Hierarchical rose-petal surfaces delay the early-stage bacterial biofilm growth. Langmuir 2019, 35(45), 14670-14680.
- Gogulancea V, Gonzalez-Cabaleiro R, Li B, Taniguchi D, Jayathilake PG, Chen J, Wilkinson D, Swailes D, McGough S, Zuliani P, Ofiteru ID, Curtis T. Individual based model links thermodynamics, chemical speciation and environmental conditions to microbial growth. Frontiers in Microbiology 2019, 10, 1871.
- Jayathilake PG, Li B, Zuliani P, Curtis T, Chen J. Modelling bacterial twitching in fluid flows: a CFD-DEM approach. Scientific Reports 2019, 9, 14540.
- Li B, Taniguchi D, Pahala- Gedara J, Gogulancea V, Gonzalez-Cabaleiro R, Chen J, McGough AS, Ofiteru ID, Curtis TP, Zuliani P. NUFEB: A Massively Parallel Simulator for Individual-based Modelling of Microbial Communities. PLoS Computational Biology 2019, 15(2), e1007125.
- Charlton S, White M, Jana S, Eland L, Jayathilake P, Burgess J, Chen J, Wipat A, Curtis T. Regulating, Measuring, and Modeling the Viscoelasticity of Bacterial Biofilms. Journal of Bacteriology 2019, 201(18), e00101-19.
- Walters RJ, Gregory LC, Wedmore LNJ, Craig TJ, McCaffrey K, Wilkinson M, Chen J, Li Z, Elliott JR, Goodall H, Iezzi F, Livio F, Michetti AM, Roberts G, Vittori E. Dual control of fault intersections on stop-start rupture in the 2016 Central Italy seismic sequence. Earth and Planetary Science Letters 2018, 500, 1-14.
- Duan P, Xia Y, Bull S, Chen J. Finite Element Modeling of Nanoindentation Response of Elastic Fiber-Matrix Composites. Journal of Materials Research 2018, 33(17), 2494-2503.
- Duan P, Toumpaniari R, Partridge S, Birch M, Genever PA, Bull SJ, Dalgarno KW, McCaskie AW, Chen J. How cell culture conditions affect the microstructure and nanomechanical properties of extracellular matrix formed by immortalized human mesenchymal stem cells: An experimental and modelling study. Materials Science and Engineering: C 2018, 89, 149-159.
- Kandemir N, Vollmer W, Jakubovics NS, Chen J. Mechanical interactions between bacteria and hydrogels. Scientific Reports 2018, 8, 10893.
- Xia Y, Duan P, Chen J. Modelling the nanomechanical responses of biofilms grown on the indenter probe. Processes 2018, 6(7), 84.
- Cao Y, Su B, Chinnaraj S, Jana S, Bowen L, Charlton S, Duan P, Jakubovics NS, Chen J. Nanostructured titanium surfaces exhibit recalcitrance towards Staphylococcus epidermidis biofilm formation. Scientific Reports 2018, 8, 1071.
- Kandemir N, Xia Y, Duan P, Yang W, Chen J. Rheological Characterization of Agarose and Poloxamer 407 (P407) Based Hydrogels. MRS Advances 2018, 3(30), 1719-1724.
- Montalbano G, Toumpaniari S, Popov A, Duan P, Chen J, Dalgarno K, Scott III WE, Ferreira AM. Synthesis of bioinspired collagen/alginate/fibrin based hydrogels for soft tissue engineering. Materials Science & Engineering: C 2018, 91, 236-246.
- Hunt NC, Hallam D, Karimi A, Mellough CB, Chen J, Steel DHW, Lako M. 3D culture of human pluripotent stem cells in RGD-alginate hydrogel improves retinal tissue development. Acta Biomaterialia 2017, 49, 329-343.
- Jayathilake PG, Gupta P, Li B, Madsen C, Oyebamiji O, Gonzalez-Cabaleiro R, Rushton S, Bridgens B, Swailes D, Allen B, McGough AS, Zuliani P, Ofiteru ID, Wilkinson DJ, Chen J, Curtis TP. A mechanistic individual-based model of microbial communities. PLoS One 2017, 12(8), e0181965.
- Sun W, Huang Y, Yin T, Wang J, Du R, Qiu J, Zhang Y, Wang Y, Chen J, Wang G. Effects of elemene on inhibiting proliferation of vascular smooth muscle cells and promoting reendothelialization at the stent implantation site. Biomaterials Science 2017, 5(6), 1144-1155.
- Jayathilake P, Jana S, Rushton S, Swailes D, Bridgens B, Curtis T, Chen J. Extracellular Polymeric Substance Production and Aggregated Bacteria Colonization Influence the Competition of Microbes in Biofilms. Frontiers in Microbiology 2017, 8, 1-14.
- Zou D, Wang W, Lei D, Yin Y, Ren P, Chen J, Yin T, Wang B, Wang G, Wang Y. Penetration of blood–brain barrier and antitumor activity and nerve repair in glioma by doxorubicin-loaded monosialoganglioside micelles system. International Journal of Nanomedicine 2017, 12, 4879-4889.
- Duan P, Kandemir N, Wang J, Chen J. Rheological Characterization of Alginate Based Hydrogels for Tissue Engineering. MRS Advances 2017, 2(24), 1309-1314.
- Popov AA, Montalbano G, Scott WE, Chen J, Shaw JAM, Dalgarno K, Ferreira-Duarte AM. 3D manufactured islet micro-tissues for the treatment of type-1 diabetes. In: TERMIS-EU 2016 Conference. 2016, Uppsala, Sweden: eCM.
- Cao Y, Duan P, Chen J. Modelling the nanomechanical response of micro particle-matrix system for nanoindentation tests. Nanotechnology 2016, 27(19), 195703.
- Chen J. Thin film coatings and the biological interface. In: Griesser, A, ed. Thin Film Coatings for Biomaterials and Biomedical Applications. Cambridge: Woodhead, 2016, pp.143-164.
- Chen J. A non-destructive approach to determine fracture toughness of coating: Nanoindentation tests and analysis. In: Sam Zhang, ed. Thin Films and Coatings: Toughening and Toughness Characterisation. CRC Press, 2015, pp.123-178.
- Chen J, Bader DL, Lee DA, Knight MM. Finite element analysis of mechanical deformation of chondrocyte to 2D substrate and 3D scaffold. Journal of Mechanics in Medicine and Biology 2015, 15.
- Ammar Y, Swailes DC, Bridgens BN, Chen J. Influence of surface roughness on the initial formation of biofilm. Surface and Coatings Technology 2015, 284, 410-416.
- Duan P, Bull SJ, Chen J. Modeling the nanomechanical responses of biopolymer composites during the nanoindentation. Thin Solid Films 2015, 596, 277-281.
- Chen J. Nanoindentation for fracture toughness of coatings. In: Thin Films and Coatings: Toughening and Toughness Characterization. Boca Raton: CRC Press, 2015, pp.123-177.
- Duan P, Chen J. Nanomechanical and microstructure analysis of extracellular matrix layer of immortalized cell line Y201 from human mesenchymal stem cells. Surface Coating & Technology 2015.
- Chen J. Nanobiomechanics of living cells: a review. Interface Focus 2014, 4(2), 20130055.
- Chen J, Wright KE, Birch MA. Nanoscale viscoelastic properties and adhesion of polydimethylsiloxane for tissue engineering. Acta Mechanica Sinica 2014, 30(1), 2-6.
- Zhang MG, Chen J, Feng XQ, Cao YP. On the Applicability of Sneddon’s Solution for Interpreting the Indentation of Nonlinear Elastic Biopolymers. Journal of Applied Mechanics 2014, 81(9), 09101-1-091011-7.
- DeSilva RT, Pasbakhsh P, Goh KL, Chai SP, Chen J. Synthesis and characterisation of poly (lactic acid)/halloysite bionanocomposite films. Journal of Composite Materials 2014, 48(30), 3705-3717.
- Chen J, Stewart T. Finite element analysis of nanoindentation of chondrocytes. In: TCES. 2013, Cardiff, UK: Swiss Society for Biomaterials.
- Chen J, Bull SJ. Finite Element Modelling of Delamination in Multilayer Coatings. Nanoscience and Nanotechnology Letters 2013, 5(7), 795-800.
- Chen J, Capstick M. Spatial dependent mechanical properties of hydroxyapatite biopolymers composite for tissue engineering. In: Tissue and Cell Engineering Society (TCES) Annual Meeting. 2013, Cardiff, UK: AO Research Institute Davos.
- Chen J. Understanding the nanoindentation mechanisms of a microsphere for biomedical applications. Journal of Physics D: Applied Physics 2013, 46, 495303.
- Chen J, Irianto J, Inamdar S, Pravincumar P, Lee DA, Bader DL, Knight MM. Cell Mechanics, Structure, and Function Are Regulated by the Stiffness of the Three-Dimensional Microenvironment. Biophysical Journal 2012, 103(6), 1188-1197.
- Chen J, Lu GX. Finite element modelling of nanoindentation based methods for mechanical properties of cells. Journal of Biomechanics 2012, 45(16), 2810-2816.
- Chen JJ. Indentation-based methods to assess fracture toughness for thin coatings. Journal of Physics D: Applied Physics 2012, 45(20), 203001.
- Chen J. On the determination of coating toughness during nanoindentation. Surface and Coatings Technology 2012, 206(13), 3064-3068.
- Chen JJ, Bull SJ. Approaches to investigate delamination and interfacial toughness in coated systems: an overview. Journal of Physics D: Applied Physics 2011, 44(3), 034001.
- Chen J, Bader DL, Lee DA, Knight MM. Finite element modeling of cell deformation when chondrocyte seeded agarose is subjected to compression. In: 8th International Conference on Cell & Stem Cell Engineering (ICCE). 2011, Ireland: Springer.
- Chen JJ, Birch MA, Bull SJ. Nanomechanical characterization of tissue engineered bone grown on titanium alloy in vitro. Journal of Materials Science: Materials in Medicine 2010, 21(1), 277-282.
- Chen JJ, Lin ZS, Bull SJ, Phillips CL, Bristowe PD. Experimental and modelling techniques for assessing the adhesion of very thin coatings on glass. Journal of Physics D: Applied Physics 2009, 42(21), 214003.
- Chen JJ, Bull SJ. Finite element analysis of contact induced adhesion failure in multilayer coatings with weak interfaces. Thin Solid Films 2009, 517(13), 3704-3711.
- Chen J, Birch MA, Bull SJ, Roy S. Microstructure and nanomechanical characterization of tissue engineered bone deposited on titanium alloy scaffolds. European Cells and Materials Suppl. 2 2009, 18(s.2), 53-53.
- Chen JJ, Bull SJ. Modelling the limits of coating toughness in brittle coated systems. Thin Solid Films 2009, 517(9), 2945-2952.
- Chen J, Bull SJ, Roy S, Kapoor A, Mukaibo H, Nara H, Momma T, Osaka T, Shacham-Diamand Y. Nanoindentation and nanowear study of Sn and Ni-Sn coatings. Tribology International 2009, 42(6), 779-791.
- Chen J, Bull SJ. On the factors affecting the critical indenter penetration for measurement of coating hardness. Vacuum 2009, 83(6), 911-920.
- Chen J, Bull SJ. Relation between the ratio of elastic work to the total work of indentation and the ratio of hardness to Young's modulus for a perfect conical tip. Journal of Materials Research 2009, 24(3), 590-598.
- Chen J, Bull SJ. The investigation of creep of electroplated Sn and Ni-Sn coating on copper at room temperature by nanoindentation. Surface and Coatings Technology 2009, 203(12), 1609-1617.
- Chen J, Bull S. A modified model to determine limiting values of coating toughness by nanoindentation. Tribology - Materials, Surfaces and Interfaces 2008, 2(4), 219-224.
- Chen J, Bull SJ. Investigation of the relationship between work done during indentation and the hardness and Young's modulus obtained by indentation testing. International Journal of Materials Research 2008, 99(8), 852-857.
- Chen J, Bull SJ, Roy S, Mukaibo H, Nara H, Momma T, Osaka T, Shacham-Diamand Y. Mechanical analysis and in situ structural and morphological evaluation of Ni-Sn alloy anodes for Li ion batteries. Journal of Physics D: Applied Physics 2008, 41(2), 025302.
- Chen J, Bull SJ. Modelling of indentation damage in single and multilayer coatings. In: Proceeding of International Union of Theoretical and Applied Mechanics (IUTAM) Symposium on Modelling Nanomaterials and Nanosystems. 2008, Aalborg, Denmark.
- Chen J, Bull SJ. Multi-cycling nanoindentation study on thin optical coatings on glass. Journal of Physics D: Applied Physics 2008, 41(7), 074009.
- Chen J, Bull SJ. FEM Investigation of the relationship between the work done by indentation and the hardness and Young’s modulus obtained from indentation load-displacement curves. In: Proceedings of the 6th International Conference on materials Processing for Properties and Performance. 2007, Beijing, China.
- Chen J, Bull SJ. Indentation fracture and toughness assessment for thin optical coatings on glass. Journal of Physics D: Applied Physics 2007, 40(18), 5401-5417.
- Chen J, Bull SJ. Loading rate effects on the fracture behaviour of solar control coatings during nanoindentation. Thin Solid Films 2007, 516(2-4), 128-135.
- Chen J, Bull SJ. Modelling the limits of coating toughness during nanoindentation. In: Proc. 6th Int. Conf. on materials Processing for Properties and Performance. 2007, Beijing, China, Sept. 13–16 (2007).
- Chen J, Bull SJ. A critical examination of the relationship between plastic deformation zone size and Young's modulus to hardness ratio in indentation testing. Journal of Materials Research 2006, 21(10), 2617-2627.
- Chen J, Bull SJ. A new method based on work-displacement curve to assess the toughness of coated system. In: Surface Engineering for Manufacturing Applications. 2006, Boston, MA: Materials Research Society.
- Chen J, Bull SJ. An energy based model to estimate coating toughness in the case that there is no excursion in the load-displacement curve. In: Materials Science and Technology (MS&T) 2006. 2006, Duke Energy Center, Cincinnati, Ohio, USA: The Minerals, Metals & Materials Society.
- Chen J, Bull SJ. Assessment of the adhesion of ceramic coatings. In: CIMTEC. 2006, Acireale, Sicily: Trans Tech Publications Ltd.
- Chen J, Bull SJ. Assessment of the toughness of thin coatings using nanoindentation under displacement control. In: 32nd International Conference on Metallurgical Coatings and Thin Film. 2006, San Diego, CA: Thin Solid Films, Elsevier SA.
- Chen J, Bull SJ. On the relationship between plastic zone radius and maximum depth during nanoindentation. Surface and Coatings Technology 2006, 201(7), 4289-4293.
- Chen J, Bull SJ. A new method based on the work-displacement curve to asses the toughness of coated systems. In: Materials Research Society Symposium Proceedings. 2005, Boston, USA: Materials Research Society.