Centre for Synthetic Biology and the Bioeconomy

Staff Profile

Dr Wendy Smith

Senior Research Associate


Wendy is a member of the Interdisciplinary Computing and Complex Biosystems group and a senior research associate based in the Synthetic Biology wet lab in the Centre for Bacterial Cell Biology (CBCB), Newcastle University.

Wendy studied Medical Microbiology at Newcastle University and her PhD thesis was entitled ‘A functional genomic analysis of group A streptococcal virulence factors’. Her initial research involved investigating the mechanisms of pathogenicity utilized by the Gram-positive bacteria Streptococcus pyogenes, with specific emphasis on the structure, assembly and role of pili and sortases.

Wendy first encountered the concept of ‘Synthetic Biology’ at local seminars and recognised that this was a new and ‘exciting’ area which she wanted to be involved in. Wendy has now been working on projects in this field since June 2010. Her current work involves developing systems for monitoring and measuring the metabolic load imposed on Bacillus subtilis and Escherichia coli chassis when synthetic parts/systems are integrated into them. Recently, she has also worked on synthetic quorum peptide mediated communication systems in B. subtilis.