Abstract

Synthetic biology has already revolutionized production paradigms in many different fields. These remarkable achievements have largely been ‘one-offs’ since each one is a special case and though they must be regarded as milestones in the respective field they do not provide a comprehensive and coherent engineering framework. Doulix aims at removing the barriers to the full exploitation of synthetic biology by offering a highly integrated toolkit based on computer aided design (CAD) tools and a comprehensive in vivo characterization of biological parts. I will present the ongoing efforts to the implementation of our web-based platform with a focus on a recently developed protocol for the fine characterization of genetic elements in E. coli, our chosen chassis, by means of a benchtop bioreactor.

Biography

Dario Cecchi is currently the head of the Synthetic Biology Laboratory at Doulix, a business unit of Explora Biotech S. r. l. After graduating as a Master of Science in 2012 in Molecular and Industrial Biotechnologies at the University of Bologna under the supervision of Prof. A. Danielli, he was hired as a graduate intern at the Centre for Genomic Regulation (Barcelona) under the supervision of Dr. R. Johnson. He obtained a PhD in Biomolecular Sciences in 2017 at the University of Trento under the supervision of Prof. S. Mansy and during that period he spent few months as a visiting PhD student at the Centre for Protolife Research (Bristol) under the supervision of Prof. S. Mann.