Staff Profile

Dr Simon Hill is a Consultant in Clinical Pharmacology & Therapeutics and Clinical Toxicologist with a specialist interest in drug misuse, particularly new psychoactive substances.

He is the Director of undergraduate medical education at Newcastle upon Tyne Hospitals working closely with Newcastle University Medical School to ensure excellence in medical education for students based in Newcastle Hospitals.

He is module lead for Drug Discovery and Development at Masters (MRes) level and has a particular interest in Chemical, Biological, Radiation and Nuclear medicine.

He is training programme director for Clinical Pharmacology & Therapeutics in the North East HEE region

• Hill SL, Dunn M, Cano C, Harnor SJ, Hardcastle IR, Grundlingh J, Dargan PI, Wood DM, Tucker S, Bartram T, Thomas SHL. Human Toxicity Caused by Indole and Indazole Carboxylate Synthetic Cannabinoid Receptor Agonists: From Horizon Scanning to Notification. Clinical Chemistry 2018, 64(2), 346-354.
• Tait RJ, Caldicott D, Mountain D, Hill SL, Lenton S. A systematic review of adverse events arising from the use of synthetic cannabinoids and their associated treatment. Clinical Toxicology 2016, 54(1), 1-13.
• Thomas S, Dunn M, Hill SL, Abouchedid R, Dargan P, Wood D, Acheampong P, Kamour A, Tucker S, Grundlingh J, Officer J, Eddleston M. Analytically confirmed exposure to novel psychoactive substances in patients presenting to hospital with severe clinical toxicity in the United Kingdom. Results from the Identification Of Novel psychoActive substances (IONA) study. In: North American Congress of Clinical Toxicology (NACCT) 2016. 2016, Boston, MA, USA: Taylor & Francis.
• Hill SL, Najafi J, Dunn M, Acheampong P, Kamour A, Grundlingh J, Blain PG, Thomas SHL. Clinical toxicity following analytically confirmed use of the synthetic cannabinoid receptor agonist MDMB-CHMICA. A report from the Identification Of Novel psychoActive substances (IONA) study. Clinical Toxicology 2016, 54(8), 638-643.
• Elamin MEMO, Dunn M, Hill SL, Thomas SHL. Convulsions associated with analytically confirmed phenibut ingestion. In: 36th International Congress of the European Association of Poisons Centres and Clinical Toxicologists (EAPCCT). 2016, Madrid, Spain: Taylor & Francis.
• Hill SL, Thomas SHL. Drugs of abuse. Medicine 2016, 44(3), 160-169.
• Waugh J, Najafi J, Hawkins L, Hill SL, Eddleston M, Vale JA, Thompson JP, Thomas SHL. Epidemiology and clinical features of toxicity following recreational use of synthetic cannabinoid receptor agonists: a report from the United Kingdom National Poisons Information Service. Clinical Toxicology 2016, 54(6), 512-518.
• Hill SL, Dunn M, Najafi J, Abouchedid R, Dargan PI, Wood DM, Thomas SHL. Identification of novel psychoactive substances in biological samples from patients with severe clinical toxicity in the UK: preliminary results from the Identification Of Novel psychoActive substances (IONA) study. In: 36th International Congress of the European Association of Poisons Centres and Clinical Toxicologists (EAPCCT). 2016, Madrid, Spain: Taylor & Francis Inc.
• Hawkins L, George NC, Hill SL, Thomas SHL, Eddleston M, Thompson JP, Vale JA. Paediatric battery ingestion: the experience of the UK National Poisons Information Service (NPIS). In: 36th International Congress of the European Association of Poisons Centres and Clinical Toxicologists (EAPCCT). 2016, Madrid, Spain: Taylor & Francis Inc.
• Hill SL, Hawkins L, Jackson G, Eddleston M, Thompson JP, Vale JA, Thanacoody HKR, Thomas SHL. Patterns of presentation and clinical toxicity after reported use of methiopropamine: a report from the UK National Poisons Information Service (NPIS). In: 36th International Congress of the European Association of Poisons Centres and Clinical Toxicologists (EAPCCT). 2016, Madrid, Spain: Taylor & Francis Inc.
• Najafi J, Dunn M, Hill SL, Thomas SHL. Severe clinical toxicity following analytically confirmed use of the synthetic cannabinoid receptor agonist MDMB-CHMICA: a report from the Identification Of Novel psychoActive substance study (IONA). In: 36th International Congress of the European Association of Poisons Centres and Clinical Toxicologists (EAPCCT). 2016, Madrid, Spain: Taylor & Francis.
• Najafi J, Waugh J, Hawkins L, Hill SL, Eddleston M, Vale JA, Thompson JP, Thomas SHL. Toxicity following recreational use of synthetic cannabinoid receptor agonists and the impact of legal control measures: a report from the UK's National Poisons Information Service. In: 36th International Congress of the European Association of Poisons Centres and Clinical Toxicologists (EAPCCT). 2016, Madrid, Spain: Taylor & Francis.
• Hill SL, Hawkins L, Jackson G, Eddleston M, Thompson JP, Vale JA, Thanacoody HKR, Thomas SHL. Toxicity of 2,4 dinitrophenol: impact of public health measures discouraging use on episodes of toxicity referred to the UK National Poisons Information Service. In: 36th International Congress of the European Association of Poisons Centres and Clinical Toxicologists (EAPCCT). 2016, Madrid, Spain: Taylor & Francis.
• Hill SL, Thomas SHL, Flecknell PA, Thomas AA, Morris CM, Henderson D, Dunn M, Blain PG. Rapid and equivalent systemic bioavailability of the antidotes HI-6 and dicobalt edetate via the intraosseous and intravenous routes. Emergency Medicine Journal 2015, 32(8), 626-631.
• Elamin MEMO, Peart LC, Hill SL, Thomas SHL. Impact of changes in UK management advice for paracetamol overdose on the numbers of adult patients admitted and treated in Newcastle upon Tyne?. In: XXXIV International Congress of the European Association of Poisons Centres and Clinical Toxicologists (EAPCCT). 2014, Brussels, Belgium: Informa Healthcare.
• Hill SL, Harbon S, Coulson J, Cooper GA, Jackson G, Lupton DJ, Vale JA, Thomas SHL. Methoxetamine toxicity reported to the National Poisons Information Service: clinical characteristics and patterns of enquiries (including the period of the introduction of the UK's first Temporary Class Drug Order). Emergency Medicine Journal 2014, 31(1), 45-47.
• Kamour A, James D, Lupton DJ, Cooper G, Eddleston M, Vale A, Thompson JP, Thanacoody R, Hill SL, Thomas SHL. Patterns of presentation and clinical features of toxicity after reported use of ([2-aminopropyl]-2,3-dihydrobenzofurans), the 'benzofuran' compounds. A report from the United Kingdom National Poisons Information Service. Clinical Toxicology 2014, 52(10), 1025-1031.
• Kamour A, James D, Spears R, Cooper G, Lupton DJ, Eddleston M, Thompson JP, Vale JA, Thanacoody HKR, Hill SL, Thomas SHL. Patterns of presentation and clinical toxicity after reported use of alpha methyltryptamine in the United Kingdom. A report from the UK National Poisons Information Service. Clinical Toxicology 2014, 52(3), 192-197.
• Kamour A, James D, Spears R, Cooper G, Lupton DJ, Eddleston M, Thompson JP, Vale JA, Thanacoody RHK, Hill S, Thomas SHL. Patterns of presentation and clinical toxicity after reported use of alpha methyltryptamine in the United Kingdom: A report from the UK National Poisons Information Service. In: XXXIV International Congress of the European Association of Poisons Centres and Clinical Toxicologists (EAPCCT). 2014, Brussels, Belgium: Informa Healthcare.
• Kamour A, Gwynnette D, George N, Cooper G, Lupton DJ, Eddleston M, Thompson JP, Vale JA, Thanacoody RHK, Hill S, Thomas SHL. Severe toxicity after use of 2,4-dinitrophenol reported to the UK National Poisons Information Service. In: XXXIV International Congress of the European Association of Poisons Centres and Clinical Toxicologists (EAPCCT). 2014, Brussels, Belgium: Informa Healthcare.
• Kamour A, James D, Lupton DJ, Cooper G, Eddleston M, Vale JA, Thompson JP, Thanacoody RHK, Hill SL, Thomas SHL. Toxicity after reported use of "benzofury" compounds ([2-aminopropyl]-2,3-dihydrobenzofurans) compared with mephedrone: A report from the UK National Poisons Information Service. In: XXXIV International Congress of EAPCCT. 2014, Brussels, Belgium: Informa Healthcare.
• Wood DM, Hill SL, Thomas SHL, Dargan PI. Using poisons information service data to assess the acute harms associated with novel psychoactive substances. Drug Testing and Analysis 2014, 6(7-8), 850-860.
• Hill SL, Harbon S, Cooper GA, Coulson JA, Thompson J, Jackson G, Lupton DJ, Vale JA, Thomas SHL. Methoxetamine toxicity reported to the National Poisons Information Service: Clinical characteristics and the effect of the UK's first Temporary Class Drug Order. In: XXXIII International Congress of the European Association of Poisons Centres and Clinical Toxicologists (EAPCCT). 2013, Copenhagen, Denmark: Informa Healthcare.
• Hill SL, Doris T, Gurung S, Katebe S, Lomas A, Dunn M, Blain P, Thomas SHL. Severe clinical toxicity associated with analytically confirmed recreational use of 25I–NBOMe: case series. Clinical Toxicology 2013, 51(6), 487-492.
• Hill SL, Cooper GA, Jackson G, Lupton DJ, Bradberry S, Thomas SHL. What's on the 'Spice' rack? Synthetic cannabinoid receptor agonist toxicity reported to the UK National Poisons Information Service. In: XXXIII International Congress of the European Association of Poisons Centres and Clinical Toxicologists (EAPCCT). 2013, Copenhagen, Denmark: Informa Healthcare.
• Hill SL, Thomas SHL. Clinical toxicology of newer recreational drugs. Clinical Toxicology 2011, 49(8), 705-719.
• Perera N, Eddleston M, Hill SL, Alldridge G, Thomas SH. Characteristics and Management of Poisoning with Ethylene Glycol and Methanol in the United Kingdom. In: International Congress of the European Association of Poisons Centres and Clinical Toxicologists. 2010, Bordeaux, France: Informa Healthcare.
• Hill SL, El-Khayat RH, Sandilands EA, Thomas SHL. Electrocardiographic effects of methylphenidate overdose. Clinical Toxicology 2010, 48(4), 342-346.
• Hill SL, El-Khayat R, Sandilands E, Thomas SHL. Methylphenidate Toxicity: A Study of Dose Dependent Adverse Drug Effects Using Patients with Methylphenidate Overdose. In: International Congress of the European Association of Poisons Centres and Clinical Toxicologists. 2010, Bordeaux, France: Clinical Toxicology, Informa Healthcare.
• Hill SL, Jefferson R, Thomas SHL. Neutropenia and Cardiac Enzyme Elevation Following Inhalational Aluminium Phosphide Exposure. In: International Congress of the European Association of Poisons Centres and Clinical Toxicologists. 2010, Bordeaux, France: Clinical Toxicology, Informa Healthcare.
• Al Banaa I, Hawkins L, Hill SL, Lupton DJ, Jackson G, Sandilands EA, Bradberry SM, Thompson JP, Rushton S, Thomas SHL. Effect of the UK Psychoactive Substances Act 2016 on episodes of toxicity related to new psychoactive substances as reported to the National Poisons Information Service. A time series analysis. International Journal of Drug Policy 2020, 77, 102672.
• Potts AJ, Cano C, Thomas SHL, Hill SL. Synthetic cannabinoid receptor agonists: classification and nomenclature. Clinical Toxicology 2020, 58(2), 82-98.
• White JC, Wood DM, Hill SL, Eddleston M, Officer J, Dargan PI, Dunn M, Thomas SHL. Acute toxicity following analytically confirmed use of the novel psychoactive substance (NPS) methiopropamine. A report from the Identification Of Novel psychoActive substances (IONA) study. Clinical Toxicology 2019, 57(7), 663-667.
• Hill SL, Dargan PI. Patterns of Acute Toxicity Associated with New Psychoactive Substances. In: Brandt SM; Maurer H, ed. Handbook of Experimental Pharmacology. Berlin, Heidelberg: Springer, 2018, pp.1-20.
• Kamour A, George N, Gwynette D, Cooper G, Lupton D, Eddleston M, Thompson JP, Vale JA, Thanacoody HK, Hill SL, Thomas SH. Increasing frequency of severe clinical toxicity after use of 2,4-dinitrophenol in the UK: a report from the National Poisons Information Service. Emergency Medicine Journal 2015, 32, 383-386.
• Blanco G, Vidler D, Roper C, Wood DM, Dargan PI, Keating L, Macfarlane R, Emmett S, Johnson G, Eddleston M, Hill SL, Thomas SHL. Acute toxicity from the synthetic cathinone N-ethylpentylone (ephylone) in the United Kingdom. Clinical Toxicology 2021, 59(12), 1270-1273.
• Hayden M, Cashman J, Ketchin A, Macfarlane R, Issa S, Eddleston M, Hines S, Hudson S, Hill SL, Thomas SHL. Detection of flubromazolam in patients with suspected non-medical drug use attending emergency departments in the United Kingdom. Clinical Toxicology 2022, 60(1), 33-37.