Staff Profile

Introduction

I am a Principal Investigator in the Newcastle University Translational and Clinical Research Institute and a member of the Regenerative Medicine, Stem Cells and Transplantation Research Theme. My work covers basic, translational and clinical studies into the aetiology, mechanisms, prognosis and therapeutics of inflammatory and fibrotic lung diseases. Major research themes include a specific interest in the optimisation of donor organs prior to lung transplantation, early outcomes after transplantation and chronic lung allograft dysfunction (CLAD).

Roles and Responsibilities

Honorary Consultant Chest and Transplant Physician, Newcastle Upon Tyne Hospital NHS Foundation Trust 

Academic Director, Institute of Transplantation, Freeman Hospital, Newcastle Upon Tyne.

Deputy Director, NIHR Blood and Transplantation Research Unit in Organ Donation and Transplantation 

Board of Directors of International Society of Heart and Lung Transplantation 2013-2016

Past-President International Society for Heart and Lung Transplantation 2017-2018

Chair of the European Respiratory Society Lung Transplantation Group  Sept 2010- Sept 2013

Chair of the British Thoracic Society Science and Research Committee    Dec 2009- Dec 2012

Qualifications

BMedSci First Class

BMBS

FRCP (London)

FRCP (Edinburgh)

PhD

Memberships

Association of Physicians of UK and Ireland

British Thoracic Society

European Thoracic Society

International Society of Heart and Lung Transplantation

European Society for Organ Transplantation 

Honours and Awards

MRC Clinical Training Fellow 1996-1999

GSK Clinical Fellow 2005-2010

Research Interests

Acute Lung injury
Pulmonary Innate Immunity
COPD
Pulmonary Fibrosis
Cystic Fibrosis
Airway remodelling in chronic lung disease
Pulmonary Hypertension
Lung Transplantation

Collaborators

NIHR Blood and Transplant Research Unit 

Other Expertise

Honorary Consultant Respiratory Physician
Institute of Transplantation, Freeman Hospital

Esteem Indicators

Board of Directors and Past-President  ISHLT

Director British Thoracic Society Lung Transplant Course 2004-present

Co-director Wellcome 4ward North Clinical PhD Academy

Funding

Medical Research Council

Wellcome Trust

National Institute for Health Research 

• Articles

  • Pradere P, Le Pavec J, Bos S, Pozza A, Nair A, Meachery G, Lordan J, Humbert M, Mercier O, Fadel E, Savale L, Fisher AJ. Outcomes of listing for lung and heart–lung transplantation in pulmonary hypertension: comparative experience in France and the UK. ERJ Open Research 2024, 10(1), 00521.
  • Hunter B, Nicorescu I, Foster E, McDonald D, Hulme G, Fuller A, Thomson A, Goldsborough T, Hilkens CMU, Majo J, Milross L, Fisher A, Bankhead P, Wills J, Rees P, Filby A, Merces G. OPTIMAL: An OPTimized Imaging Mass cytometry AnaLysis framework for benchmarking segmentation and data exploration. Cytometry Part A 2024, 105(1), 36-53.
  • Milross L, Hunter B, McDonald D, Merces G, Thomson A, Hilkens CMU, Wills J, Rees P, Jiwa K, Cooper N, Majo J, Ashwin H, Duncan CJA, Kaye PM, Bayraktar OA, Filby A, Fisher AJ. Distinct lung cell signatures define the temporal evolution of diffuse alveolar damage in fatal COVID-19. eBioMedicine 2024, 99, 104945.
  • Chilvers NJS, Gilmour J, Brown ML, Bates L, Pang CY, Pauli H, Dark J, Fisher AJ. A Split-Lung Ex Vivo Perfusion Model for Time- and Cost-Effective Evaluation of Therapeutic Interventions to the Human Donor Lung. Transplant International 2024, 37, 12573.
  • Trotter PB, Dark J, Fisher AJ, Robb M, Watson C, Neuberger J. Transplantation of Organs From DCD and DBD Donors Who Died After Ligature Asphyxiation. Transplantation 2023, 107(2), 529-539.
  • Bos S, Majo J, Funston W, Fisher AJ, Meachery G. Silicone depositions: An unusual finding in the explanted and newly transplanted lungs. Thorax 2023, 79(1), 98-99.
  • Pither T, Wang L, Bates L, Morrison M, Charlton C, Griffiths C, Macdonald J, Bigley V, Mavridou M, Barsby J, Borthwick L, Dark J, Scott W, Ali S, Fisher AJ. Modeling the Effects of IL-1β-mediated Inflammation During Ex Vivo Lung Perfusion Using a Split Human Donor Model. Transplantation 2023, 107(10), 2179-2189.
  • Sabater L, Gossart JB, Hernandez I, Rico D, Blanchard A, Borthwick LA, Fisher AJ, Majo J, Jiwa K, Collins A, Abbate G, Oakley F, Mann DA, Mann J. miRNA Expression in Fibroblastic Foci within Idiopathic Pulmonary Fibrosis Lungs Reveals Novel Disease-Relevant Pathways. American Journal of Pathology 2023, 193(4), 417-429.
  • Leong SW, Bos S, Lordan JL, Nair A, Fisher AJ, Meachery G. Lung transplantation for interstitial lung disease: evolution over three decades. BMJ Open Respiratory Research 2023, 10(1), e001387.
  • Ashwin H, Milross L, Wilson J, Majo J, Hang Lee JT, Calder G, Hunter B, James S, Lagos D, Signoret N, Filby A, Bayraktar OA, Fisher AJ, Kaye PM. Identification of a protein expression signature distinguishing early from organising diffuse alveolar damage in COVID-19 patients. Journal of Clinical Pathology 2023, 76(8), 561-565.
  • Fabre T, Barron AMS, Christensen SM, Asano S, Bound K, Lech MP, Wadsworth MH, Chen X, Wang C, Wang J, McMahon J, Schlerman F, White A, Kravarik KM, Fisher AJ, Borthwick LA, Hart KM, Henderson NC, Wynn TA, Dower K. Identification of a broadly fibrogenic macrophage subset induced by type 3 inflammation. Science Immunology 2023, 8(82).
  • Dey S, Ashwin H, Milross L, Hunter B, Majo J, Filby AJ, Fisher AJ, Kaye PM, Lagos D. Downregulation of MALAT1 is a hallmark of tissue and peripheral proliferative T cells in COVID-19. Clinical and Experimental Immunology 2023, 212(3), 262-275.
  • Ferdinand JR, Morrison MI, Andreasson A, Charlton C, Chhatwal AK, Scott WE, Borthwick LA, Clatworthy MR, Fisher AJ. Transcriptional analysis identifies potential novel biomarkers associated with successful ex-vivo perfusion of human donor lungs. Clinical Transplantation 2022, 36(4), e14570.
  • Milross L, Majo J, Pulle J, Hoggard S, Cooper N, Hunter B, Duncan CJA, Filby A, Fisher AJ. The trajectory of COVID-19 cardiopulmonary disease: insights from an autopsy study of community-based, pre-hospital deaths. ERJ Open Research 2022, 8(4), 00303-2022.
  • Meng B, Abdullahi A, Ferreira IATM, Goonawardane N, Saito A, Kimura I, Yamasoba D, Gerber PP, Fatihi S, Rathore S, Zepeda SK, Papa G, Kemp SA, Ikeda T, Toyoda M, Tan TS, Kuramochi J, Mitsunaga S, Ueno T, Shirakawa K, Takaori-Kondo A, Brevini T, Mallery DL, Charles OJ, Bowen JE, Joshi A, Walls AC, Jackson L, Martin D, Smith KGC, Bradley J, Briggs JAG, Choi J, Madissoon E, Meyer KB, Mlcochova P, Ceron-Gutierrez L, Doffinger R, Teichmann SA, Fisher AJ, Pizzuto MS, de Marco A, Corti D, Hosmillo M, Lee JH, James LC, Thukral L, Veesler D, Sigal A, Sampaziotis F, Goodfellow IG, Matheson NJ, Sato K, Gupta RK. Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicity. Nature 2022, 603(7902), 706-714.
  • Guo-Parke H, Linden D, Mousnier A, Scott IC, Killick H, Borthwick LA, Fisher AJ, Weldon S, Taggart CC, Kidney JC. Altered Differentiation and Inflammation Profiles Contribute to Enhanced Innate Responses in Severe COPD Epithelium to Rhinovirus Infection. Frontiers in Medicine 2022, 9, 741989.
  • Guillotin D, Taylor AR, Plate M, Mercer PF, Edwards LM, Haggart R, Miele G, McAnulty RJ, Maher TM, Hynds RE, Jamal-Hanjani M, Marshall RP, Fisher AJ, Blanchard AD, Chambers RC. Transcriptome analysis of IPF fibroblastic foci identifies key pathways involved in fibrogenesis. Thorax 2021, 76(1), 73-82.
  • Hardman G, Sutcliffe R, Hogg R, Mumford L, Grocott L, Mead-Regan S-J, Nuttall J, Dunn S, Seeley P, Clark S, Quigley R, Al-Attar N, Booth K, Dark JH, Fisher AJ. The impact of the SARS-CoV-2 pandemic and COVID-19 on lung transplantation in the UK: Lessons learned from the first wave. Clinical Transplantation 2021, 35(3), e14210.
  • Bryant JM, Brown KP, Burbaud S, Everall I, Belardinelli JM, Rodriguez-Rincon D, Grogono DM, Peterson CM, Verma D, Evans IE, Ruis C, Weimann A, Arora D, Malhotra S, Bannerman B, Passemar C, Templeton K, MacGregor G, Jiwa K, Fisher AJ, Blundell TL, Ordway DJ, Jackson M, Parkhill J, Floto RA. Stepwise pathogenic evolution of Mycobacterium abscessus. Science 2021, 372(6541), eabb8699.
  • Wilkinson AL, John AE, Barrett JW, Gower E, Morrison VS, Man Y, Pun KT, Roper JA, Luckett JC, Borthwick LA, Barksby BS, Burgoyne RA, Barnes R, Fisher AJ, Procopiou PA, Hatley RJD, Barrett TN, Marshall RP, Macdonald SJF, Jenkins RG, Slack RJ. Pharmacological characterisation of GSK3335103, an oral αvβ6 integrin small molecule RGD-mimetic inhibitor for the treatment of fibrotic disease. European Journal of Pharmacology 2021, 913, 174618.
  • Thompson ER, Bates L, Ibrahim IK, Sewpaul A, Stenberg B, McNeill A, Figueiredo R, Girdlestone T, Wilkins GC, Tingle SJ, Scott WE, Lamos H, Mellor AL, Roobrouck VD, Ting AE, Hosgood SA, Nicholson ML, Fisher AJ, Ali S, Sheerin NS, Wilson CH. Novel delivery of cellular therapy to reduce ischaemia reperfusion injury in kidney transplantation. American Journal of Transplantation 2021, 21(4), 1402-1414.
  • Hardman G, Sutcliffe R, Hogg R, Mumford L, Grocott L, Jerrett L, Mead-Regan S-J, Nuttall J, Dunn S, Seeley P, Quigley R, Dalzell JR, Al-Attar N, Parameshwar J, Fisher AJ, Booth K, Dark JH. Heart transplantation in the UK during the first wave of the SARS-CoV-2 pandemic. Clinical Transplantation 2021, 35(5), e14261.
  • Lin JH, Taggart M, Borthwick L, Fisher A, Brodlie M, Sassano MF, Tarran R, Gray MA. Acute cigarette smoke or extract exposure rapidly activates TRPA1-mediated calcium influx in primary human airway smooth muscle cells. Scientific Reports 2021, 11(1), 9643.
  • John AE, Graves RH, Pun KT, Vitulli G, Forty EJ, Mercer PF, Morrell JL, Barrett JW, Rogers RF, Hafeji M, Bibby LI, Gower E, Morrison VS, Man Y, Roper JA, Luckett JC, Borthwick LA, Barksby BS, Burgoyne RA, Barnes R, Le J, Flint DJ, Pyne S, Habgood A, Organ LA, Joseph C, Edwards-Pritchard RC, Maher TM, Fisher AJ, Gudmann NS, Leeming DJ, Chambers RC, Lukey PT, Marshall RP, Macdonald SJF, Jenkins RG, Slack RJ. Translational pharmacology of an inhaled small molecule αvβ6 integrin inhibitor for idiopathic pulmonary fibrosis. Nature Communications 2020, 11(1), 4659.
  • Cunningham PS, Meijer P, Nazgiewicz A, Anderson SG, Borthwick LA, Bagnall J, Kitchen GB, Lodyga M, Begley N, Venkateswaran RV, Shah R, Mercer PF, Durrington HJ, Henderson NC, Piper-Hanley K, Fisher AJ, Chambers RC, Bechtold DA, Gibbs JE, Loudon AS, Rutter MK, Hinz B, Ray DW, Blaikley JF. The circadian clock protein REVERBα inhibits pulmonary fibrosis development. Proceedings of the National Academy of Sciences of the United States of America 2020, 117(2), 1139-1147.
  • Gardner AI, Haq IJ, Simpson AJ, Becker KA, Gallagher J, Saint-Criq V, Verdon B, Mavin E, Trigg A, Gray MA, Koulman A, McDonnell MJ, Fisher AJ, Kramer EL, Clancy JP, Ward C, Schuchman EH, Gulbins E, Brodlie M. Recombinant Acid Ceramidase Reduces Inflammation and Infection in Cystic Fibrosis. American Journal of Respiratory and Critical Care Medicine 2020, 202(8), 1133-1145.
  • Gilmour J, Griffiths C, Pither T, Scott WE, Fisher AJ. Normothermic machine perfusion of donor-lungs ex-vivo: promoting clinical adoption. Current Opinion in Organ Transplantation 2020, 25(3), 285-292.
  • Ball SL, Cockell SJ, Wilson JA, Mann DA, Fisher AJ. Microarray analysis of primary epithelial and fibroblast cells in chronic rhinosinusitis without nasal polyps. Rhinology 2020, 58(6), 581-587.
  • Hardman G, Hogg R, Rushton S, Booth K, Fisher AJ, Dark JH. Lung Transplantation and Utilisation Following Donation after Circulatory Death (DCD) in the UK. The Journal of Heart and Lung Transplantation 2020, 39(4), S139-S139.
  • Peacock AJ, Ling Y, Johnson MK, Kiely DG, Condliffe R, Elliot CA, Gibbs JSR, Howard LS, Pepke-Zaba J, Sheares KKK, Corris PA, Fisher AJ, Lordan JL, Gaine S, Coghlan JG, Wort SJ, Gatzoulis MA. Idiopathic pulmonary arterial hypertension and co-existing lung disease: is this a new phenotype?. Pulmonary Circulation 2020, 10(1).
  • Leslie J, Millar BJM, del Carpio Pons A, Burgoyne RA, Frost JD, Barksby BS, Luli S, Scott J, Simpson JA, Gauldie J, Murray LA, Finch DK, Carruthers AM, Ferguson J, Sleeman MA, Rider D, Howarth R, Fox C, Oakley F, Fisher AJ, Mann DA, Borthwick LA. FPR-1 is an important regulator of neutrophil recruitment and a tissue-specific driver of pulmonary fibrosis. JCI Insight 2020, 5(4), e125937.
  • Leslie J, Garcia Macia M, Luli S, Worrell JC, Reilly W, Paish HL, Knox A, Barksby BS, Gee LM, Zaki MYW, Collins A, Burgoyne RA, Cameron R, Bragg C, Xu X, Chung GW, Brown CDA, Blanchard AD, Nanthakumar CB, Karsdal M, Robinson SM, Manas DM, Sen G, French J, White SA, Murphy S, Trost M, Zakrzewski JL, Klein U, Schwabe RF, Mederacke I, Nixon C, Bird T, Teuwen LA, Schoonjans L, Carmeliet P, Mann J, Fisher AJ, Sheerin NS, Borthwick LA, Mann DA, Oakley F. c-Rel orchestrates energy-dependant epithelial and macrophage reprogramming in fibrosis. Nature Metabolism 2020, 2, 1350-1367.
  • Worrell J, Leslie J, Smith GR, Zaki M, Paish H, Knox A, James ML, Cartwright TN, OReily S, Kania G, Distler O, Distler J, Herrick A, Jeziorska M, Borthwick LA, Fisher AJ, Mann J, Mann DA, Oakley F. cRel expression regulates distinct transcriptional and functional profiles driving fibroblast matrix production in systemic sclerosis. Rheumatology 2020, 59(12), 3939-3951.
  • Ladak SS, Roebuck E, Powell J, Fisher AJ, Ward C, Ali S. The role of miR-200b-3p in modulating TGF-β1 induced injury in human bronchial epithelial cells. Transplantation 2019, 103(11), 2275-2286.
  • Woodcock HV, Eley JD, Guillotin D, Plate M, Nanthakumar CB, Martufi M, Peace S, Joberty G, Poeckel D, Good RB, Taylor AR, Zinn N, Redding M, Forty EJ, Hynds RE, Swanton C, Karsdal M, Maher TM, Fisher A, Bergamini G, Marshall RP, Blanchard AD, Mercer PF, Chambers RC. The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis. Nature Communications 2019, 10, 6.
  • Tji-JoongGan C, Ward C, Meachery G, Lordan J, Fisher AJ, Corris PA. Long-term effect of azithromycin in bronchiolitis obliterans syndrome. BMJ Open Respiratory Research 2019, 6(1), e000465.
  • McMeekin N, Chrysos AE, Vale L, Fisher AJ. Incorporating ex-vivo lung perfusion into the UK adult lung transplant service: an economic evaluation and decision analytic model. BMC Health Services Research 2019, 19, 326.
  • Akram AR, Avlonitis N, Scholefield E, Vendrell M, McDonald N, Aslam T, Craven TH, Gray C, Collie DS, Fisher AJ, Corris PA, Walsh T, Haslett C, Bradley M, Dhaliwal K. Enhanced avidity from a multivalent fluorescent antimicrobial peptide enables pathogen detection in a human lung model. Scientific Reports 2019, 9, 8422.
  • Kunadian V, Wilson N, Stocken D, Hani A, McColl E, Burns G, Howe N, Fisher A, De Soyza A. Antiplatelet therapy in the primary prevention of cardiovascular diseasein patients with chronic obstructive pulmonary disease: a randomised controlled proof-of-concept trial. ERJ Open Research 2019, 5(3).
  • Birch J, Sunny SS, Hester KLM, Parry G, Kate Gould F, Dark JH, Clark SC, Meachery G, Lordan J, Fisher AJ, Corris PA, De Soyza A. Outcomes of lung transplantation in adults with bronchiectasis. BMC Pulmonary Medicine 2018, 18, 82.
  • Pradere P, Tudorache I, Magnusson J, Savale L, Brugiere O, Douvry B, Reynaud-Gaubert M, Claustre J, Borgne AL, Holm AM, Schultz HH, Knoop C, Godinas L, Fisher AJ, Hirschi S, Gottlieb J, Le Pavec J. Lung transplantation for scleroderma lung disease: An international, multicenter, observational cohort study. Journal of Heart and Lung Transplantation 2018, 37(7), 903-911.
  • Greer M, Berastegui C, Jaksch P, Benden C, Aubert J, Roux A, Lhuillier E, Hirschi S, Reynaud-Gaubert M, Philit F, Claustre J, LePalud P, Stern M, Knoop C, Vos R, Verschuuren E, Fisher A, Riise G, Hansson L, Iversen M, Hämmäinen P, Wedel H, Smits J, Gottlieb J, Holm AM. Lung transplantation after allogeneic stem cell transplantation: a pan-European experience. European Respiratory Journal 2018, 51(2), 1701330.
  • Clifford RL, Fishbane N, Patel J, MacIsaac JL, McEwen LM, Fisher AJ, Brandsma C-A, Nair P, Kobor MS, Hackett T-L, Knox AJ. Altered DNA methylation is associated with aberrant gene expression in parenchymal but not airway fibroblasts isolated from individuals with COPD. Clinical Epigenetics 2018, 10(1), 32.
  • Andreasson ASI, Borthwick LA, Gillespie C, Jiwa K, Scott J, Henderson P, Mayes J, Romano R, Roman M, Ali S, Fildes JE, Marczin N, Dark JH, Fisher AJ, on behalf of the DEVELOP-UK Investigators. The role of interleukin-1β as a predictive biomarker and potential therapeutic target during clinical ex vivo lung perfusion. Journal of Heart and Lung Transplantation 2017, 36(9), 985-995.
  • Alfred A, Taylor PC, Dignan F, El-Ghariani K, Griffin J, Gennery AR, Bonney D, Das-Gupta E, Lawson S, Malladi RK, Douglas KW, Maher T, Guest J, Hartlett L, Fisher AJ, Child F, Scarisbrick JJ. The role of extracorporeal photopheresis in the management of cutaneous T-cell lymphoma, graft-versus-host disease and organ transplant rejection: a consensus statement update from the UK Photopheresis Society. British Journal of Haematology 2017, 177(2), 287-310.
  • Sithamparanathan S, Nair A, Thirugnanasothy L, Coghlan JG, Condliffe R, Dimopoulos K, Elliot CA, Fisher AJ, Gaine S, Gibbs JSR, Gatzoulis MA, E Handler C, Howard LS, Johnson M, Kiely DG, Lordan JL, Peacock AJ, Pepke-Zaba J, Schreiber BE, Sheares KKK, Wort SJ, Corris PA. Survival in portopulmonary hypertension: Outcomes of the United Kingdom National Pulmonary Arterial Hypertension Registry. Journal of Heart and Lung Transplantation 2017, 36(7), 770-779.
  • Andreasson ASI, Karamanou DM, Gillespie CS, Özalp F, Butt T, Hill P, Jiwa K, RWalden H, Green NJ, Borthwick LA, Clark SC, Pauli H, Gould KF, Corris PA, Ali S, Dark JH, Fisher AJ. Profiling inflammation and tissue injury markers in perfusate and bronchoalveolar lavage fluid during human ex vivo lung perfusion. European Journal of Cardio-thoracic Surgery 2017, 51(3), 577-586.
  • Dongre A, Clements D, Fisher AJ, Johnson SR. Cathepsin K in Lymphangioleiomyomatosis: LAM Cell-Fibroblast Interactions Enhance Protease Activity by Extracellular Acidification. The American Journal of Pathology 2017, 187(8), 1750-1762.
  • Haworth CS, Banks J, Capstick T, Fisher AJ, Gorsuch T, Laurenson IF, Leitch A, Loebinger MR, Milburn HJ, Nightingale M, Ormerod P, Shingadia D, Smith D, Whitehead N, Wilson R, Floto RA. British thoracic society guideline for the management of non-tuberculous mycobacterial pulmonary disease (NTM-PD). BMJ Open Respiratory Research 2017, 4(1), e000242.
  • Ruttens D, Verleden SE, Bijnens EM, Winckelmans E, Gottlieb J, Warnecke G, Meloni F, Morosini M, Van Der Bij W, Verschuuren EA, Sommerwerck U, Weinreich G, Kamler M, Roman A, Gomez-Olles S, Berastegui C, Benden C, Holm AM, Iversen M, Schultz HH, Luijk B, Oudijk E-J, Kwakkel-Van Erp JM, Jaksch P, Klepetko W, Kneidinger N, Neurohr C, Corris P, Fisher AJ, Lordan J, Meachery G, Piloni D, Vandermeulen E, Bellon H, Hoffmann B, Vienneau D, Hoek G, De Hoogh K, Nemery B, Verleden GM, Vos R, Nawrot TS, Vanaudenaerde BM. An association of particulate air pollution and traffic exposure with mortality after lung transplantation in Europe. European Respiratory Journal 2017, 49(1), 1600484.
  • Ball SL, Mann DA, Wilson JA, Fisher AJ. The Role of the Fibroblast in Inflammatory Upper Airway Conditions. American Journal of Pathology 2016, 186(2), 225-233.
  • Bartis D, Crowley LE, D'Souza VK, Borthwick L, Fisher AJ, Croft AP, Pongracz JE, Thompson R, Langman G, Buckley CD, Thickett DR. Role of CD248 as a potential severity marker in idiopathic pulmonary fibrosis. BMC Pulmonary Medicine 2016, 16, 51.
  • Fisher AJ, Yadegarfar ME, Collerton J, Small T, Kirkwood TBL, Davies K, Jagger C, Corris PA. Respiratory health and disease in a UK population-based cohort of 85 year olds: The Newcastle 85+ Study. Thorax 2016, 71(3), 255-266.
  • Sithamparanathan S, Thirugnanasothy L, Morley KE, Fisher AJ, Lordan JL, Meachery G, Parry G, Corris PA. Observational Study of Methotrexate in the Treatment of Bronchiolitis Obliterans Syndrome. Transplatation Proceedings 2016, 48(10), 3387-3392.
  • Sithamparanathan S, Thirugnanasothy L, Clark S, Dark JH, Fisher AJ, Gould KF, Hasan A, Lordan JL, Meachery G, Parry G, Corris PA. Observational study of lung transplant recipients surviving 20 years. Respiratory Medicine 2016, 117, 103-108.
  • Borthwick LA, Barron L, Hart KM, Vannella KM, Thompson RW, Oland S, Cheever A, Sciurba J, Ramalingam TR, Fisher AJ, Wynn TA. Macrophages are critical to the maintenance of IL-13-dependent lung inflammation and fibrosis. Mucosal Immunology 2016, 9(1), 38-55.
  • Fisher A, Andreasson A, Chrysos A, Lally J, Mamasoula C, Exley C, Wilkinson J, Qian J, Watson G, Lewington O, Chadwick T, McColl E, Pearce M, Mann K, McMeekin N, Vale L, Tsui S, Yonan N, Simon A, Marczin N, Mascaro J, Dark J. An observational study of Donor Ex Vivo Lung Perfusion in UK Lung Transplantation : DEVELOP-UK. Health Technology Assessment 2016, 20(85).
  • Borthwick LA, Suwara MI, Carnell SC, Green NJ, Mahida R, Dixon D, Gillespie CS, Cartwright TN, Horabin J, Walker A, Olin E, Rangar M, Gardner A, Mann J, Corris PA, Mann DA, Fisher AJ. Pseudomonas aeruginosa induced Airway Epithelial Injury Drives Fibroblast Activation: A Mechanism in Chronic Lung Allograft Dysfunction. American Journal of Transplantation 2016, 16(6), 1751-1765.
  • Wilson CL, Murphy LB, Leslie J, Kendrick S, French J, Fox CR, Sheerin NS, Fisher A, Robinson JH, Tiniakos DG, Gray DA, Oakley F, Mann DA. Ubiquitin C-terminal hydrolase 1: A novel functional marker for liver myofibroblasts and a therapeutic target in chronic liver disease. Journal of Hepatology 2015, 63(6), 1421-1428.
  • Church AC, Martin DH, Wadsworth R, Bryson G, Fisher AJ, Welsh DJ, Peacock AJ. The reversal of pulmonary vascular remodeling through inhibition of p38 MAPK-alpha: a potential novel anti-inflammatory strategy in pulmonary hypertension. American Journal of Physiology: Lung Cellular and Molecular Physiology 2015, 309(4), L333-L347.
  • Ball SL, Suwara MI, Borthwick LA, Wilson JA, Mann DA, Fisher AJ. How Reliable are Sino-Nasal Cell Lines for Studying the Pathophysiology of Chronic Rhinosinusitis?. Annals of Otology, Rhinology & Laryngology 2015, 124(6), 437-442.
  • Birch J, Anderson RK, Correia-Melo C, Jurk D, Hewitt G, Marques FM, Green NJ, Moisey E, Birrell MA, Belvisi MG, Black F, Taylor JJ, Fisher AJ, De Soyza A, Passos JF. DNA damage response at telomeres contributes to lung aging and chronic obstructive pulmonary disease. American Journal of Physiology: Lung Cellular and Molecular Physiology 2015, 309(10), L1124-L1137.
  • Corris PA, Ryan VA, Small T, Lordan J, Fisher AJ, Meachery G, Johnson G, Ward C. A randomised controlled trial of azithromycin therapy in Bronchiolitis Obliterans Syndrome (BOS) post lung transplantation . Thorax 2015, 70(5), 442-450.
  • Andreasson A, Karamanou DM, Perry JD, Perry A, Özalp F, Butt T, Morley KE, Walden HR, Clark SC, Prabhu M, Corris PA, Gould K, Fisher AJ, Dark JH. The effect of ex vivo lung perfusion on microbial load in human donor lungs. Journal of Heart and Lung Transplantation 2014, 33(9), 910-916.
  • Thakrar MV, Morley K, Lordan JL, Meachery G, Fisher AJ, Parry G, Corns PA. Pregnancy after lung and heart-lung transplantation. Journal of Heart and Lung Transplantation 2014, 33(6), 593-598.
  • Suwara MI, Vanaudenaerde BM, Verleden SE, Vos R, Green NJ, Ward C, Borthwick LA, Vandermeulen E, Lordan J, Van Raemdonck DE, Corris PA, Verleden GM, Fisher AJ. Mechanistic differences between phenotypes of chronic lung allograft dysfunction after lung transplantation. Transplant International 2014, 27(8), 857-867.
  • Suwara MI, Green NJ, Borthwick LA, Mann J, Mayer-Barber KD, Barron L, Corris PA, Farrow SN, Wynn TA, Fisher AJ, Mann DA. IL-1α released from damaged epithelial cells is sufficient and essential to trigger inflammatory responses in human lung fibroblasts. Mucosal Immunology 2014, 7(3), 684-693.
  • Jones AL, Fisher AJ, Mahida R, Gould K, Perry JD, Hannan MM, Judge EP, Brown R, Boagey K, Goodfellow M. Nocardia kroppenstedtii sp nov., an actinomycete isolated from a lung transplant patient with a pulmonary infection. International Journal of Systematic and Evolutionary Microbiology 2014, 64, 751-754.
  • Borthwick LA, Corris PA, Mahida R, Walker A, Gardner A, Suwara M, Johnson GE, Moisey EJ, Brodlie M, Ward C, Perry JD, de Soyza A, Mann DA, Fisher AJ. TNFα From Classically Activated Macrophages Accentuates Epithelial to Mesenchymal Transition in Obliterative Bronchiolitis. American Journal of Transplantation 2013, 13(3), 621-633.
  • Mackay LS, Dodd S, Dougall IG, Tomlinson W, Lordan J, Fisher AJ, Corris PA. Isolation and characterisation of human pulmonary microvascular endothelial cells from patients with severe emphysema. Respiratory Research 2013, 14, 23.
  • Borthwick LA, Gardner A, De Soyza A, Mann DA, Fisher AJ. Transforming Growth Factor-β1 (TGF-β1) Driven Epithelial to Mesenchymal Transition (EMT) is Accentuated by Tumour Necrosis Factor α (TNFα) via Crosstalk Between the SMAD and NF-κB Pathways. Cancer Microenvironment 2012, 5(1), 45-57.
  • Borthwick LA, Gardner A, De-Soyza A, Mann DA, Fisher AJ. Transforming Growth Factor-β1 (TGF-β1) Driven Epithelial to Mesenchymal Transition (EMT) is Accentuated by Tumour Necrosis Factor α (TNFα) via Crosstalk Between the SMAD and NF-κB Pathways. Cancer Microenvironment 2012, 5(1), 45-57.
  • Gardner A, Fisher AJ, Richter C, Johnson GE, Moisey EJ, Brodlie M, Ward C, Krippner-Heidenreich A, Mann DA, Borthwick LA. The Critical Role of TAK1 in Accentuated Epithelial to Mesenchymal Transition in Obliterative Bronchiolitis after Lung Transplantation. American Journal of Pathology 2012, 180(6), 2293-2308.
  • Haja Mydin H, Corris PA, Nicholson A, Perry JD, Meachery G, Marrs EC, Peart S, Fagan C, Lordan JL, Fisher AJ, Gould FK. Targeted Antibiotic Prophylaxis for Lung Transplantation in Cystic Fibrosis Patients Colonised with Pseudomonas aeruginosa Using Multiple Combination Bactericidal Testing. Journal of Transplantation 2012, 2012, 135738.
  • Gorowiec MR, Borthwick LA, Parker SM, Kirby JA, Saretzki GC, Fisher AJ. Free radical generation induces epithelial-to-mesenchymal transition in lung epithelium via a TGF-beta 1-dependent mechanism. Free Radical Biology & Medicine 2012, 52(6), 1024-1032.
  • Mahida RY, Wiscombe S, Fisher AJ. Current status of lung transplantation. Chronic Respiratory Disease 2012, 9(2), 131-145.
  • Ling Y, Johnson MK, Kiely DG, Condliffe R, Elliot CA, Gibbs JS, Howard LS, Pepke-Zaba J, Sheares KK, Corris PA, Fisher AJ, Lordan JL, Gaine S, Coghlan JG, Wort SJ, Gatzoulis MA, Peacock AJ. Changing demographics, epidemiology, and survival of incident pulmonary arterial hypertension: results from the pulmonary hypertension registry of the United Kingdom and Ireland. American Journal of Respiratory and Critical Care Medicine 2012, 186(8), 790-796.
  • Savelev S, Perry J, Bourke S, Taylor R, Fisher A, Corris P, Jary H, Petrie M, De Soyza A. Volatile biomarkers of Pseudomonas aeruginosa in cystic fibrosis and non cystic fibrosis bronchiectasis. Letters in Applied Microbiology 2011, 52(6), 610-613.
  • Lee WT, Kirkham N, Johnson MK, Lordan JL, Fisher AJ, Peacock AJ. Sitaxentan-related acute liver failure in a patient with pulmonary arterial hypertension. European Respiratory Journal 2011, 37(2), 472-474.
  • Brodlie M, McKean MC, Johnson GE, Anderson AE, Hilkens CM, Fisher AJ, Corris PA, Lordan JL, Ward C. Raised interleukin-17 is immunolocalised to neutrophils in cystic fibrosis lung disease. European Respiratory Journal 2011, 37(6), 1378-1385.
  • Borthwick LA, Botha P, Verdon B, Brodlie MJ, Gardner A, Bourn D, Johnson GE, Gray MA, Fisher AJ. Is CFTR-delF508 Really Absent from the Apical Membrane of the Airway Epithelium?. PLoS One 2011, 6(8).
  • Borthwick LA, Sunny SS, Oliphant V, Perry J, Brodlie M, Johnson GE, Ward C, Gould K, Corris PA, De Soyza A, Fisher AJ. Pseudomonas aeruginosa accentuates epithelial-to-mesenchymal transition in the airway. European Respiratory Journal 2011, 37(5), 1237-1247.
  • Brodlie M, McKean MC, Johnson GE, Perry JD, Nicholson A, Verdon B, Gray MA, Dark JH, Pearson JP, Fisher AJ, Corris PA, Lordan J, Ward C. Primary bronchial epithelial cell culture from explanted cystic fibrosis lungs. Experimental Lung Research 2010, 36(2), 101-110.
  • De Soyza A, Meachery G, Hester KLM, Nicholson A, Parry G, Tocewicz K, Pillay T, Clark S, Lordan JL, Schueler S, Fisher AJ, Dark JH, Gould FK, Corris PA. Lung transplantation for patients with cystic fibrosis and Burkholderia cepacia complex infection: A single-center experience. Journal of Heart and Lung Transplantation 2010, 29(12), 1395-1404.
  • Borthwick LA, McIlroy EI, Gorowiec MR, Brodlie M, Johnson GE, Ward C, Lordan JL, Corris PA, Kirby JA, Fisher AJ. Inflammation and Epithelial to Mesenchymal Transition in Lung Transplant Recipients: Role in Dysregulated Epithelial Wound Repair. American Journal of Transplantation 2010, 10(3), 498-509.
  • Rostron AJ, Cork DMW, Avlonitis VS, Fisher AJ, Dark JH, Kirby JA. Contribution of Toll-Like Receptor Activation to Lung Damage After Donor Brain Death. Transplantation 2010, 90(7), 732-739.
  • Brodlie M, McKean MC, Johnson GE, Gray J, Fisher AJ, Corris PA, Lordan JL, Ward C. Ceramide is Increased in the Lower Airway Epithelium of People with Advanced Cystic Fibrosis Lung Disease. American Journal of Respiratory and Critical Care Medicine 2010, 182(3), 369-375.
  • Borthwick LA, Parker SM, Brougham KA, Johnson GE, Gorowiec MR, Ward C, Lordan JL, Corris PA, Kirby JA, Fisher AJ. Epithelial to mesenchymal transition (EMT) and airway remodelling after human lung transplantation. Thorax 2009, 64(9), 770-777.
  • Ward C, Eger K, Diboll J, Jones D, Haniffa MA, Fisher A, Brodlie M, Lordan JL, Corris PA, Hilkens CM. Bronchial epithelial cells cultured from clinically stable lung allograft patients promote the development of macrophages from monocytes rather than dendritic cells. Thorax 2009, 64(5), 430-435.
  • Botha P, Archer L, Anderson RL, Lordan JL, Dark JH, Corris PA, Gould KA, Fisher AJ. Pseudomonas aeruginosa colonization of the allograft after lung transplantation and the risk of bronchiolitis obliterans syndrome. Transplantation 2008, 85(5), 771-774.
  • Meachery G, De Soyza A, Nicholson A, Parry G, Hasan A, Tocewicz K, Pillay T, Clark S, Lordan JL, Schueler S, Fisher AJ, Dark JH, Gould FK, Corris PA. Outcomes of lung transplantation for cystic fibrosis in a large UK cohort. Thorax 2008, 63(8), 725-731.
  • Murphy DM, Forrest IA, Corris PA, Johnson GE, Small T, Jones D, Fisher AJ, Egan JJ, Cawston TE, Lordan JL, Ward C. Azithromycin attenuates effects of lipopolysaccharide on lung allograft bronchial epithelial cells. The Journal of Heart and Lung Transplantation 2008, 27(11), 1210-6.
  • Anderson RL, Hiemstra PS, Ward C, Forrest IA, Murphy D, Proud D, Lordan J, Corris PA, Fisher AJ. Antimicrobial Peptides in Lung Transplant Recipients with Bronchiolitis Obliterans Syndrome. European Respiratory Journal 2008, 32(3), 670-677.
  • Parker SM, Goriwiec MR, Borthwick LA, Johnson G, Ward C, Lordan JL, Corris PA, Saretzki GC, Fisher AJ. Airway epithelial cell senescence in the lung allograft. American Journal of Transplantation 2008, 8(7), 1544-1549.
  • Mackay LS, Anderson RL, Parry G, Lordan J, Corris PA, Fisher AJ. Pulmonary fibrosis: Rate of disease progression as a trigger for referral for lung transplantation. Thorax 2007, 62(12), 1069-1073.
  • Murphy DM, Ward C, Forrest IA, Pritchard G, Jones D, Stovold R, Fisher AJ, Cawston TE, Lordan JL, Corris PA. The phosphodiesterase type IV inhibitor cilomilast decreases pro-inflammatory cytokine production from primary bronchial epithelial cells in lung transplantation patients. The Journal of Heart and Lung Transplantation 2006, 25(12), 1436-1440.
  • Fisher AJ, Rutherford RM, Bozzino J, Parry G, Dark JH, Corris PA. The safety and efficacy of total lymphoid irradiation in progressive bronchiolitis obliterans syndrome after lung transplantation. American Journal of Transplantation 2005, 5(3), 537-543.
  • Arcasoy SM, Fisher A, Hachem RR, Scavuzzo M, Ware LB. Report of the ISHLT Working Group on Primary Lung Graft Dysfunction part V: Predictors and outcomes. Journal of Heart and Lung Transplantation 2005, 24(10), 1483-1488.
  • Rutherford RM, Fisher AJ, Hilton C, Forty J, Hasan A, Gould FK, Dark JH, Corris PA. Functional status and quality of life in patients surviving 10 years after lung transplantation. American Journal of Transplantation 2005, 5(5), 1099-1104.
  • Yates B, Murphy DM, Forrest IA, Ward C, Rutherford RM, Fisher AJ, Lordan JL, Dark JH, Corris PA. Azithromycin reverses airflow obstruction in established bronchiolitis obliterans syndrome. American Journal of Respiratory and Critical Care Medicine 2005, 172(6), 772-775.
  • Ward C, De Soyza A, Fisher AJ, Pritchard G, Forrest I, Corris P. A descriptive study of small airway reticular basement membrane thickening in clinically stable lung transplant recipients. Journal of Heart and Lung Transplantation 2005, 24(5), 533-537.
  • Ward C, De Soyza A, Fisher AJ, Pritchard G, Forrest IA, Corris PA. Reticular basement membrane thickening in airways of lung transplant recipients is not affected by inhaled corticosteroids. Clinical and Experimental Allergy 2004, 34(12), 1905-1909.
  • Fisher AJ, Donnelly SC, Pritchard G, Dark JH, Corris PA. Objective evaluation of selection criteria to assess donor lung suitability show poor discrimination of infection or inflammation. Thorax 2004, 59(5), 434-438.
  • Fisher AJ, Donnelly SC, Pritchard G, Dark JH, Corris PA. Objective assessment of criteria for selection of donor lungs suitable for transplantation. Thorax 2004, 59(5), 434-437.
  • Fisher AJ, Wardle J, Dark JH, Corris PA. Non-immune acute graft injury after lung transplantation and the risk of subsequent bronchiolitis obliterans syndrome (BOS). Journal of Heart and Lung Transplantation 2002, 21(11), 1206-1212.
  • De Soyza A, Fisher AJ, Small T, Corris PA. Inhaled corticosteroids and the treatment of lymphocytic bronchiolitis following lung transplantation. American Journal of Respiratory and Critical Care Medicine 2001, 164(7), 1209-1212.
  • Fisher AJ, Donnelly SC, Hirani N, Haslett C, Strieter RM, Dark JH, Corris PA. Elevated levels of interleukin-8 in donor lungs is associated with early graft failure after lung transplantation. American Journal of Respiratory and Critical Care Medicine 2001, 163(1), 259-265.
  • Fisher AJ, Donnelly SC, Hirani N, Burdick MD, Strieter RM, Dark JH, Corris PA. Enhanced pulmonary inflammation in organ donors following fatal non-traumatic brain injury. Lancet 1999, 353(9162), 1412-1413.
  • A. J. Fisher, J. H. Dark and P. A. Corris. Improving donor lung evaluation: a new approach to increase organ supply for lung transplantation. Thorax 1998, 53, 818-820.
  • E. Gabbay, A. J. Fisher, T. Small, A. J. Leonard and P. A. Corris. Exhaled single-breath nitric oxide measurements are reproducible, repeatable and reflect levels of nitric oxide found in the lower airways. European Respiratory Journal 1998, 11, 467-472.
  • Gabbay E, Fisher AJ, Small T, Leonard AJ, Corris PA. Exhaled single-breath nitric oxide measurements are reproducible, repeatable and reflect levels of nitric oxide found in the lower airways. EUROPEAN RESPIRATORY JOURNAL 1998, 11(2), 467-472.
  • A. J. Fisher, E. Gabbay, T. Small, S. Doig, J. H. Dark and P. A. Corris. Cross sectional study of exhaled nitric oxide levels following lung transplantation. Thorax 1998, 53, 454-458.
  • Fisher AJ, Gabbay E, Small T, Doig S, Dark JH, Corris PA. Cross sectional study of exhaled nitric oxide levels following lung transplantation. THORAX 1998, 53(6), 454-458.

• Conference Proceedings (inc. Abstracts)

  • Marshall C, Still M, Hassenfuss J, Stoniute A, Crooks J, Craig D, Sniehotta F, Exley C, Fisher A, Beyer F. Barriers, facilitators and interventions concerning organ donation in people from minority ethnic backgrounds: updating the evidence base. In: British Transplant Society Congress 2020 “Collaboration in Transplantation”. 2020, Belfast.
  • Marshall C, Still M, Hassenfuss J, Stoniute A, Crooks J, Craig D, Sniehotta F, Exley C, Fisher A, Beyer F. Barriers and facilitators to organ donation in people from minority ethnic backgrounds: a logic model. In: British Transplant Society Congress 2020 “Collaboration in Transplantation”. 2020, Belfast.
  • Wang L, Wang T, Rushton SN, Fisher AJ, Sheerin NS, Dark JH. Severe acute kidney injury after cardiac transplantation is a marker of poor early outcome and impacts on late renal function -- a UK cohort study. In: 39th International Society for Heart and Lung Transplantation Annual Meeting. 2019, Orlando, Florida: Elsevier.
  • Wang L, Andreasson A, Straughan C, Sims AJ, Brennan KJ, Fisher AJ, Clark SC, Parry G, Booth KL, Dark JH. Developing DSA Post-Lung Transplant - Identifying Risk Factors. In: 39th International Society for Heart and Lung Transplantation Annual Meeting and Scientific Sessions. 2019, Orlando, Florida USA: Elsevier.
  • Yadegarfar ME, Fisher AJ, Corris PA, Jagger C. Understanding The Relationship Between Lung Function Measures And Mortality In The Very Old. In: American Thoracic Society 2016 International Conference. 2016, San Francisco: American Thoracic Society.
  • Andreasson A, Karamanou D, Gillespie C, Borthwick L, Jiwa K, Henderson P, Ozalp F, Butt T, Clark SC, Pauli H, Corris PA, Ali S, Dark JH, Fisher AJ. Treating Donor Lung Inflammation by Blocking Interleukin-1B-An In Vitro Therapy Testing Platform for Ex Vivo Lung Perfusion. In: International Society for Heart and Lung Transplantation 36th Annual Meeting and Scientific Sessions. 2016, Washington, DC: Elsevier.
  • Miller R, Hartog B, Frew J, Parry G, Fisher A, Corris P, Meachery G, Lordan J. Total Lymphoid Irradiation (TLI) for the Management of Bronchiolitis Obliterans Syndrome (BOS) Post Lung Transplant: A Single Centre Experience. In: 36th Annual Meeting of the International Society for Heart and Lung Transplantation. 2016, Washington, DC: Elsevier.
  • Andreasson A, Yonan N, Fildes JE, Mascaro J, Marczin N, Tsui S, Simon A, Dark JH, Fisher AJ, DEVELOP-UK Investigators. Profiling Biomarkers of Inflammation and Tissue Injury during Human Ex Vivo Lung Perfusion in the DEVELOP-UK Study. In: International Society for Heart and Lung Transplantation 36th Annual Meeting and Scientific Sessions. 2016, Washington, DC: Elsevier Inc.
  • Mayes JW, Jiwa K, Leaw B, Tan J, Lau S, Borthwick L, Andreasson A, Dark J, Jenkin G, Lim R, Fisher AJ. Potential therapeutic benefits of the human amniotic epithelium cell secretome during ex-vivo perfusion of donor lungs. In: British Thoracic Society Winter Meeting 2016. 2016, London: BMJ Group.
  • Thirugnanasothy L, Sithamparanathan S, Lordan J, Fisher AJ, MacGowan G, Parry G, Corris PA. Establishing The Effect Of Targeted Therapies On Diffusing Capacity In Patients With Pulmonary Arterial Hypertension (PAH). In: American Thoracic Society 2016 International Conference. 2016, San Francisco: American Thoracic Society.
  • Fisher AJ, Yonan N, Mascaro J, Marczin N, Tsui S, Simon A, Dark J, DEVELOP-UK Investigators. A Study of Donor Ex-Vivo Lung Perfusion in UK Lung Transplantation (DEVELOP-UK). In: International Society for Heart and Lung Transplantation Annual Meeting. 2016, Washington DC: Elsevier Inc.
  • Neil DA, Andreasson A, Roman M, Romano R, Mascaro J, Tsui S, Simon A, Yonan N, Marczin N, Dark J, Fisher AJ. Ultrastructural Changes in Epithelial and Endothelial Barriers During Ex-Vivo Lung Perfusion. In: ISHLT 35th Annual Meeting and Scientific Sessions. 2015, Nice, France: Elsevier.
  • Woolcock SC, De Soyza J, Crockett R, Day M, Fisher AJ, Lordan J, MacGowan G, Corris PA. The Role of Specialist Palliative Care Services in the Management of Patients with Pulmonary Arterial Hypertension; A Review of Current Practice. In: British Thoracic Society. 2014, London, UK: BMJ Publishing Group.
  • Verleden SE, Ruttens D, Bijnens E, Winckelmans E, Meloni F, Morosini M, Gottlieb J, Warnecke G, Verschuuren E, Van der Bij W, Weinreich G, Kamler M, Sommerwerck U, Hoffmann B, Roman A, Olles SG, Benden C, Rechsteiner T, Luijck B, Oudijk E, Van Kessel D, Kwakkel-Van Erp J, Iversen M, Schultz H, Jaksch P, Klepetko W, Lordan J, Corris P, Fisher A, Holm A, Vandermeulen E, Vos R, Kneidinger N, Neurohr C, Beelen R, Vienneau D, Hoek G, De Hoogh K, Nemery B, Verleden GM, Nawrot TS, Vanaudenaerde B. The Impact of Air Pollution on Outcome After Lung Transplantation in Europe. In: International Society for Heart and Lung Transplantation 34th Annual Meeting and Scientific Sessions. 2014, San Diego, California, USA: Elsevier.
  • Sithamparanathan S, Thirugnanasothy L, Fisher AJ, Lordan J, Meachery G, Dark JH, Hasan A, Clark SC, Gould K, MacGowan GA, Parry G, Corris PA. A Retrospective Observational Study of 20 Year Lung Transplant Survivors - A Single Centre Experience. In: British Thoracic Society Winter Meeting. 2014, London, UK: BMJ Publishing Group.
  • Crackett RM, Hall A, Day MB, Desoyza JR, Small T, Fisher AJ, Lordan JL, Mac Gowan G, Corris PA. Treatment Outcomes in Pulmonary Arterial Hypertension (PHA) Associated with Systemic Sclerosis (Sscl.) in Matched Groups Using Either Bosentan or Sildenafil Monotherapy. In: ISHLT 33rd Annual Meeting & Scientific Sessions. 2013, Montreal, Canada: Elsevier.
  • Thakrar MV, Morley K, Lordan JL, Meachery GJ, Fisher AJ, Parry G, Corris PA. Pregnancy after Lung Transplantation: A Single Center Experience. In: ISHLT 33rd Annual Meeting & Scientific Sessions. 2013, Montreal, Canada: Elsevier.
  • Ranasinghe AM, Clark S, Corris PA, Fisher AJ, Gould K, Hamilton L, Lordan JL, Meachery G, Morley K, Parry G, Perry A, Pillay T, Schueler S, Tocewicz K, Dark TH. Improving Outcomes in Lung Transplantation for Cystic Fibrosis - A Unified Approach. In: ISHLT 33rd Annual Meeting & Scientific Sessions. 2013, Montreal, Canada: Elsevier.
  • Thakrar MV, Hall A, Crackett R, Day M, Mac Gowan G, Lordan JL, Fisher AJ, Treacey C, Pepke-Zaba J, Corris PA. Functional and Quality of Life Improvements in Treated Patients with Chronic Thromboembolic Pulmonary Hypertension. In: ISHLT 33rd Annual Meeting & Scientific Sessions. 2013, Montreal, Canada: Elsevier.
  • Small TM, Ward C, Lordan JL, Fisher AJ, Corris PA, Gibson GJ. Static lung volumes in lung transplant recipients with bronchiolitis obliterans syndrome. In: IRISH JOURNAL OF MEDICAL SCIENCE. 2010, 236 GRAYS INN RD, 6TH FLOOR, LONDON WC1X 8HL, ENGLAND: SPRINGER LONDON LTD.
  • Searl CP, Butt TA, Samuel A, Wrightson N, Fisher AJ, Dark JH. Novalung Enables Protective Ventilation in Primary Graft Dysfunction. In: JOURNAL OF HEART AND LUNG TRANSPLANTATION. 2010, 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA: ELSEVIER SCIENCE INC.
  • Botha P, Wrightson N, Butt T, Corris PA, Dark JH, Fisher AJ, Schueler SVB. Safe extension of ischaemic time in lung transplantation - Where is the limit?. In: JOURNAL OF HEART AND LUNG TRANSPLANTATION. 2008, 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA: ELSEVIER SCIENCE INC.
  • Maxwell S, McCall A, Corris PA, Gibson GJ, Lordan JL, Ward A, Fisher AJ, Higgins BG, De Soyza A. CARELESS NOTE-TAKING COSTS MONEY: LESSONS FROM A CODING AUDIT OF RESPIRATORY HOSPITAL EPISODES. In: THORAX. 2008, BRITISH MED ASSOC HOUSE, TAVISTOCK SQUARE, LONDON WC1H 9JR, ENGLAND: B M J PUBLISHING GROUP.
  • Cooper D, Kerr J, Parry G, Dark JH, Lordan J, Corris PA, Fisher AJ. Lung transplantation for idiopathic pulmonary fibrosis: Recipient characteristics and survival outcomes in a single centre 1987-2007. In: THORAX. 2007, BRITISH MED ASSOC HOUSE, TAVISTOCK SQUARE, LONDON WC1H 9JR, ENGLAND: B M J PUBLISHING GROUP.
  • Mackay LS, Anderson RL, Lordan J, Corris PA, Fisher AJ. Factors influencing survival to lung transplantation in patients with idiopathic pulmonary fibrosis placed on the waiting list 1999-2004. In: JOURNAL OF HEART AND LUNG TRANSPLANTATION. 2006, 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA: ELSEVIER SCIENCE INC.
  • Fisher A. The role of pulmonary innate immunity after lung transplantation. In: Innovations in Lung Transplantation. 2005, University of Pavia, Italy.

• Editorials

  • Bos S, Fisher AJ. Is downregulation of liver kinase B1 the major factor driving epithelial-to-mesenchymal transition?. American Journal of Transplantation 2022, 22(3), 689-690.
  • Fisher AJ, Rogers JG. The Journal of Heart and Lung Transplantation: A golden age draws to a close and a new dawn begins. Journal of Heart and Lung Transplantation 2021, 40(1), 3-3.
  • Martinu T, Koutsokera A, Benden C, Cantu E, Chambers D, Cypel M, Edelman J, Emtiazjoo A, Fisher AJ, Greenland JR, Hayes D, Hwang D, Keller BC, Lease ED, Perch M, Sato M, Todd JL, Verleden S, von der Thusen J, Weigt SS, Keshavjee S. International Society for Heart and Lung Transplantation consensus statement for the standardization of bronchoalveolar lavage in lung transplantation. Journal of Heart and Lung Transplantation 2020, 39(11), 1171-1190.
  • Snell GI, Yusen RD, Weill D, Strueber M, Garrity E, Reed A, Pelaez A, Whelan TP, Perch M, Bag R, Budev M, Corris PA, Crespo MM, Witt C, Cantu E, Christie JD. Report of the ISHLT Working Group on Primary Lung Graft Dysfunction, part I: Definition and grading—A 2016 Consensus Group statement of the International Society for Heart and Lung Transplantation. Journal of Heart and Lung Transplantation 2017, 36(10), 1097-1103.
  • Gelman AE, Fisher AJ, Huang HJ, Baz MA, Shaver CM, Egan TM, Mulligan MS. Report of the ISHLT Working Group on Primary Lung Graft Dysfunction Part III: Mechanisms: A 2016 Consensus Group Statement of the International Society for Heart and Lung Transplantation. Journal of Heart and Lung Transplantation 2017, 36(10), 1114-1120.
  • Fisher AJ. Azithromycin and bronchiolitis obliterans syndrome after lung transplantation: is prevention better than cure?. European Respiratory Journal 2011, 37(1), 10-12.
  • Fisher AJ. Selecting Patients Suitable for Lung Transplantation: the art of balancing risks. Expert Review of Respiratory Medicine 2007, 1(3), 299-301.
  • Fisher AJ, Dark JH, Corris PA. Improving donor lung evaluation: a new approach to increase organ supply for lung transplantation. THORAX 1998, 53(10), 818-820.

• Letters

  • Andreasson ASI, Dark JH, Fisher AJ. Reply to Mohamed S.A. Mohamed. European Journal of Cardio-Thoracic Surgery 2017, 52(3), 607-608.
  • Birch J, Victorelli S, Rahmatika D, Anderson RK, Jiwa K, Moisey E, Ward C, Fisher AJ, De Soyza AJ, Passos JF. Telomere Dysfunction and Senescence-associated Pathways in Bronchiectasis. American Journal of Respiratory and Critical Care Medicine 2016, 193(8), 929-932.
  • Badalyan V, Thompson R, Addo K, Borthwick LA, Fisher AJ, Ort T, Myers TG, Wynn TA, Ramalingam TR. TNF- α/IL-17 synergy inhibits IL-13 bioactivity via IL-13Rα2 induction. Journal of Allergy and Clinical Immunology 2014, 134(4), 975-978.

• Notes

  • Fisher AJ, Dark JH. Ex vivo repair of human donor lungs for transplantation. Nature Medicine 2020, 26, 1015-1016.
  • Woodcock HV, Eley JD, Guillotin D, Plate M, Nanthakumar CB, Martufi M, Peace S, Joberty G, Poeckel D, Good RB, Taylor AR, Zinn N, Redding M, Forty EJ, Hynds RE, Swanton C, Karsdal M, Maher TM, Fisher A, Bergamini G, Marshall RP, Blanchard AD, Mercer PF, Chambers RC. Author Correction: The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis (Nature Communications, (2019), 10, 1, (6), 10.1038/s41467-018-07858-8). Nature Communications 2020, 11(1), 4680.
  • Fisher AJ. Clinical trials of immunosuppression in lung transplantation: A coming of age. Transplantation 2006, 81(7), 980-981.

• Report

  • Marshall C, Still M, Hasenfuss J, Stoniute A, Crooks J, Craig D, Sniehotta FF, Exley C, Fisher A, Beyer FR. Identifying interventions to increase organ donation rates in people from minority ethnic backgrounds. NIHR, 2019.

• Reviews

  • Barten MJ, Fisher AJ, Hertig A. The use of extracorporeal photopheresis in solid organ transplantation—current status and future directions. American Journal of Transplantation 2024, epub ahead of print.
  • Bos S, Pradere P, Beeckmans H, Zajacova A, Vanaudenaerde BM, Fisher AJ, Vos R. Lymphocyte Depleting and Modulating Therapies for Chronic Lung Allograft Dysfunction. Pharmacological Reviews 2023, 75(6), 1200-1217.
  • Milross L, Majo J, Cooper N, Kaye PM, Bayraktar O, Filby A, Fisher AJ. Post-mortem lung tissue: the fossil record of the pathophysiology and immunopathology of severe COVID-19. The Lancet Respiratory Medicine 2022, 10(1), 95-106.
  • Bos S, Milross L, Filby AJ, Vos R, Fisher AJ. Immune processes in the pathogenesis of chronic lung allograft dysfunction: identifying the missing pieces of the puzzle. European Respiratory Review 2022, 31(165), 220060.
  • Burgoyne RA, Fisher AJ, Borthwick LA. The role of epithelial damage in the pulmonary immune response. Cells 2021, 10(10), 2763.
  • Milross L, Griffiths C, Fisher AJ. Ex Vivo Lung Perfusion: A Platform for Donor Lung Assessment, Treatment and Recovery. Transplantology 2021, 2(4), 387-395.
  • Griffiths C, Scott III WE, Ali S, Fisher AJ. Normothermic machine perfusion: a platform to assess and treat donor organs ex-situ with novel therapeutics prior to transplantation. QJM: An International Journal of Medicine 2020. In Press.
  • Morrison MI, Pither TL, Fisher AJ. Pathophysiology and classification of primary graft dysfunction after lung transplantation. Journal of Thoracic Disease 2017, 9(10), 4084-4097.
  • Haworth CS, Banks J, Capstick T, Fisher AJ, Gorsuch T, Laurenson IF, Leitch A, Loebinger MR, Milburn HJ, Nightingale M, Ormerod P, Shingadia D, Smith D, Whitehead N, Wilson R, Floto RA. British Thoracic Society guidelines for the management of non-tuberculous mycobacterial pulmonary disease (NTM-PD). Thorax 2017, 72, ii1-ii64.
  • Andreasson ASI, Dark JH, Fisher AJ. Ex vivo lung perfusion in clinical lung transplantation-State of the art. European Journal of Cardio-Thoracic Surgery 2014, 46(5), 779-788.
  • Bayes HK, Church AC, Fisher AJ, BTS Sci Res Comm. Review of the British Thoracic Society Winter Meeting 2012, 5 to 7 December, London, UK. Thorax 2013, 68(3), 277-282.
  • Borthwick LA, Wynn TA, Fisher AJ. Cytokine mediated tissue fibrosis. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2013, 1832(7), 1049-1060.
  • Bayes HK, Church AC, Fisher AJ, BTS Sci Res Comm. Review of the British Thoracic Society Winter Meeting 2011, 7-9 December, London, UK. Thorax 2012, 67(3), 258-262.
  • Mydin HH, Fisher AJ. Pulmonary hypertension and lung transplantation: Thorax publication activity review 2008-2010. Thorax 2012, 67(9), 828-831.
  • Verleden GM, Fisher AJ. Lung Transplantation and Lung Cancer: Is There a Link?. Respiration 2011, 81(6), 441-445.
  • Church C, Bayes HK, Fisher AJ, BTS Sci Res Comm. A review of the British Thoracic Society scientific meeting 1-3 December 2010. Thorax 2011, 66(3), 253-258.
  • Gardner A, Borthwick L, Fisher A. Lung epithelial wound healing in health and disease. Expert Review of Respiratory Medicine 2010, 4(5), 647-660.
  • Botha P, Fisher AJ, Dark JH. Marginal lung donors: A diminishing margin of safety?. Transplantation 2006, 82(10), 1273-1279.
  • Avlonitis VS, Fisher AJ, Kirby JA, Dark JH. Pulmonary transplantation: The role of brain death in donor lung injury. Transplantation 2003, 75(12), 1928-1933.