Staff Profile
Dr Alison Howard
Lecturer
- Telephone: +44 (0) 191 208 3476
- Address: Institute for Cell and Molecular Biosciences
Newcastle University
Medical School
Framlington Place
Newcastle upon Tyne
NE2 4HH
Qualifications
Senior Fellow of the Higher Education Academy
Professional Development Course for External Examiners (Advance HE)
Certificate in Advanced Studies in Academic Practice, Newcastle University
PhD - Gastroenterology Unit, Royal Postgraduate Medical School (RPMS), University of London
MSc - Clinical Biochemistry, Newcastle University
BSc (Hons) Medical Biochemistry -University of Surrey
Previous Positions
Teaching Fellow in Physiology (T & S) School of Biomedical Sciences, Newcastle University
Senior Scientific Specialist, Epithelial Research Group, ICAMB, Newcastle University
Research Associate, Epithelial Research Group, ICAMB, Newcastle University
Scientific Officer, Rowett Research Institute, Aberdeen
Post-doctoral Research Associate, Gastroenterology Unit, RPMS, London
Current Roles and Responsibilities
School
Senior Tutor (Bioscience Programmes)
Co-lead for EDI
Member Phase 1 Curriculum Committee
Member Physiological Sciences Curriculum Committee
Member of Board of Studies
Peer mentor coordinator
University
Member Support to Study/ Academic Progress Review working group
Member Senior Tutor Forum
Member Peer Mentor Staff coordinator forum
Member Student Experience Sub-Committee
Sexual Violence Liaison Officer (SVLO)
Student launchpad invited contributor
Member Faculty EDI Committee
Other
Member The Physiological Society Conferences Committee (2023-present)
Memberships
The Physiological Society
Senior Fellow of the Higher Education Academy
Member UKAT (UK Advising and Tutoring Association)
Since moving to a T&S role, I have incorporated my interest in transport physiology into my teaching practice, undergraduate project supervision and public engagement activities. I maintain my research interest and up-to-date subject knowledge through acting as assessment panel member and internal examiner for multiple PhD students each year (currently member on three panels).
I was the lead applicant and organiser of a successful bid to host the The Physiological Society 2026 Education and Teaching theme annual meeting at Newcastle University in April 2026: Fit For the Future: Physiology Education and Teaching in the UK
I have presented and co-presented oral and poster communications and local, national and international meetings. At the Europhysiology 2022 meeting, one of my peer-reviewed abstracts (co-authored with Dr Michele Sweeney and Dr Beth Lawry) was selected for special recognition with a Physiological Reports Abstract Award in the Education and Teaching category.
I have successfully applied for engagement activity funding from the Physiological Society to fund Physiology Friday and Physiology Week activities on multiple occasions, and following from these initiatives was awarded a Royal Society Partnership grant jointly with Dr Stephanie Bell, Durham Sixth Form centre) to develop further educational engagement activities (2025-2026).
I have reviewed abstracts, chaired sessions and judged poster and oral communications at multiple Physiological Society meetings.
I teach physiology and bioscience skills across a range of modules and degree programmes, as a lecturer, practical and seminar leader, assignment lead, assessment marker, and undergraduate project supervisor.
Module leader:
PSC1002/BSA1015 Physiology,
CMB1011 Professional and Practical Skills for Bioscientists (Assignment lead: semester 1 and 2 essays, semester 2 lab report; semester 2 oral presentation)
PSC2019 Renal and Respiratory Physiology
Other:
PSC2018 Human Anatomy for Physiologists
PSC3012 Integrated Physiology
DEN1103 Dental Physiology
PED3005 Advanced Pharmacogenetics
BMS3022 Bioethics
CMB3000
Internal Examiner and Assessor of PhD and Masters programmes.
Biomed+
Since 2016, I have organised and chaired Biomed+, an extracurricular lecture series connecting undergraduate students with leading researchers from the Faculty of Medical Sciences. The programme enriches the curriculum by exposing students to cutting-edge biomedical research and providing opportunities to engage directly with internationally recognised scientists. Over the years, contributors have included Professor Tracy Palmer FRS, Professor Martin Noble FRS, Professor Christine Harrison MBE and Professor Chris Stewart. Frequently cited as a programme highlight in student feedback and external examiner reports, the series has helped foster a stronger research culture within the undergraduate community. More recently, I have expanded the initiative to include early career researchers, providing valuable opportunities to develop their communication and teaching skills while showcasing a wider range of research and career pathways to students.
Teaching Developments
In 2023, as stage 1 curriculum chair, I led the development of a new 30-credit Stage 1 Professional and Practical Skills module designed to strengthen students’ transition into higher education and introduce professional scientific practice from the outset of their degree. The module embeds early engagement with primary scientific literature, bioinformatics, scientific writing, communication, and data analysis, providing a structured framework for longitudinal skills development. By integrating real-life research and professional practice throughout the academic year, the module provides students with the analytical, technical and transferable skills needed for success in later study, including stage 3 research projects, and their future careers.
As module lead, I led the redevelopment of PSC2019, modernising its curriculum and assessment strategy to better align with current physiological and clinical practice. By integrating clinical expertise into the teaching team, the module now provides students with stronger links between physiology and its application in healthcare. As Deputy Chair of the Physiological Sciences Curriculum Committee , I contributed to programme-level curriculum development and enhancement.
In 2025, I co-led a major review and redesign of the Stage 1 Biomedical Sciences curriculum, ensuring alignment with the Graduate Skills Framework and national sector benchmarks. As part of the new programmes (September 2026 rollout), I have developed and will co-lead a new Stage 1 core skills module that embeds teamwork, reflective practice, sustainability and research-engaged learning throughout the academic year. By introducing new pedagogical approaches and focusing on belonging, resilience and professional identity, the module provides students with a stronger foundation for academic and career success while strengthening links between teaching and research. I am also co-leading development of a new Stage 2 Physiology module, supporting coherent and progressive learning across the programme.
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Articles
- Bierhals CG, Howard A, Hirst BH. Reduction of Rapid Proliferating Tumour Cell Lines by Inhibition of the Specific Glycine Transporter GLYT1. Biomedicines 2021, 9(12), 1770.
- Ogo OA, Tyson J, Cockell SJ, Howard A, Valentine RA, Ford D. The zinc finger protein ZNF658 regulates the transcription of genes involved in zinc homeostasis and affects ribosome biogenesis through the zinc transcriptional regulatory element (ZTRE). Molecular and Cell Biology 2015, 35(6), 977-987.
- Bell S, Howard A, Wilson JA, Abbot EL, Smith WD, Townes CL, Hirst BH, Hall J. Streptococcus pyogenes infection of tonsil explants is associated with a human β-defensin 1 response from control but not recurrent acute tonsillitis patients. Molecular Oral Microbiology 2012, 27(3), 160-171.
- Howard A, Tahir I, Javed S, Waring SM, Ford D, Hirst BH. Glycine transporter GLYT1 is essential for glycine-mediated protection human intestinal epithelial cells against oxidative damage. Journal of Physiology 2010, 588(6), 995–1009.
- Howard A, Townes C, Milona P, Nile CJ, Michailidis G, Hall J. Expression and functional analyses of liver expressed antimicrobial peptide-2 (LEAP-2) variant forms in human tissues. Cellular Immunology 2010, 261(2), 128-133.
- Anderson CMH, Howard A, Walters JRF, Ganapathy V, Thwaites DT. Taurine uptake across the human intestinal brush-border membrane is via two transporters: H+-coupled PAT1 (SLC36A1) and Na+- and Cl--dependent TauT (SLC6A6). Journal of Physiology 2009, 587(4), 731-744.
- Hirst BH, Howard A, Javed S. [Meeting Abstract] Protection of intestinal cells against oxidative stress: A role for GLYT1-mediated transport. Journal of Physiological Sciences 2009, 59(s1), 247.
- Ball SL, Siou GP, Wilson JA, Howard A, Hirst BH, Hall J. Expression and immunolocalisation of antimicrobial peptides within human palatine tonsils. Journal of Laryngology and Otology 2007, 121(10), 973-978.
- Howard A, Goodlad RA, Walters JRF, Ford D, Hirst BH. Increased expression of specific intestinal amino acid and peptide transporter mRNA in rats fed by TPN is reversed by GLP-2. Journal of Nutrition 2004, 134(11), 2957-2964.
- Ball SL, Siou GP, Howard A, Hall J, Wilson JA, Hirst BH. Antimicrobial peptide expression in human tonsils. Clinical Otolaryngology & Allied Sciences 2004, 29(4), 427.
- Christie GR, Ford D, Howard A, Clark M Ann, Hirst BH. Glycine supply to human enterocytes mediated by high-affinity basolateral GLYT1. Gastroenterology 2001, 120(2), 439-448.
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Conference Proceedings (inc. Abstracts)
- Fultang L, Howard A, Hirst B. Expression of the glycine transporter type 1 (GlyT-1A) is upregulated by ATF-4 following physiological stress in human intestinal epithelial cells. In: Experimental Biology 2014. 2014, San Diego: Federation of American Societies for Experimental Biology.
- Howard A, Hirst BH. Regulation of GLYT1 and xCT in human intestinal cells by ATF4 but not XBP1 or ATF6. In: Experimental Biology Meeting 2011. 2011, Walter E Washington Convention Center, Washington, DC: Federation of American Societies for Experimental Biology.
- Mowbray CA, Howard A, Morsman J, Hirst BH. Differentiation of HepG2 and Huh7 cells using dimethyl sulfoxide. In: FASEB JOURNAL. 2010, 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 USA: FEDERATION AMER SOC EXP BIOL.
- Javed S, Howard A, Hirst B. Protection of intestinal cells against reactive oxygen species (ROS) by amino acids. In: Mutagenesis: 31st Annual Meeting of the United Kingdom Environmental Mutagen Society. 2009, University of Northumbria, Newcastle upon Tyne, UK: Oxford University Press.
- Tahir I, Howard A, Ford D, Hirst BH. Role of glycine pre-treatment and transport in intestinal cell protection. In: FASEB Journal: Experimental Biology 2005 Meeting. 2005, San Diego, California, USA: Federation of American Societies for Experimental Biology.
- Howard A, Goodlad RA, Ford D, Walters JRF, Hirst BH. Glucagon-like peptide 2 (GLP-2) abrogates the effect of total parenteral nutrition (TPN) on intestinal amino acid and peptide transporters in rats. In: Journal of Physiology: Conference of the Physiological Society. 2002, Liverpool: Wiley-Blackwell Publishing Ltd.
- Wilson V, Howard A, Ford D, Hirst BH. EGF enhanced transcription of the amino acid transporter hATB(0) in COS-7 cells. In: Journal of Physiology: Conference of the Physiological Society. 2002, Liverpool: Wiley-Blackwell Publishing Ltd.
- Howard A, Rugg-Gunn P, Goodlad RL, Walters JRF, Ford D, Hirst BH. Regional differences in small intestinal nutrient transporter transcript expression during total parenteral nutrition. In: FASEB Journal. 2001, Federation of American Societies for Experimental Biology.
- Howard A, Jordinson M, Goodlad RA, Walters JR, Ford D, Hirst BH. Changes in expression of intestinal peptide and amino acid transporters in rats fed by total parenteral nutrition. In: GASTROENTEROLOGY. 2000.
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Reviews
- Mowbray C, Howard A, Hirst BH. Quantitative PCR in the assessment of novel hepatic cell models. European Pharmaceutical Review 2015, 20(3), 8-14.
- Howard A, Hirst BH. The glycine transporter GLYT1 in human intestine: expression and function. Biological and Pharmaceutical Bulletin 2011, 34(6), 784-788.