Staff Profile

University Responsibilities 

• Degree Programme Director - MSc Clinical Science (Physiological Sciences & Medical Physics)
• Programme Director - Postgraduate Certificate Clinical Echocardiography

Qualifications

• PhD – University of Sheffield, 1997
• BSc (Hons) - University of Sheffield, 1993
• PG Cert Learning & Teaching in Higher Education - University of Teesside, 2005
• Newcastle Teaching Award, 2016

Accreditation / Professional Registration

• Registered Clinical Scientist (CS022047), Health & Care Professions Council (HCPC)
• British Society of Echocardiography Accreditation: Transthoracic Echocardiography - current
• Fellow of The Higher Education Academy

 Professional Body Membership 

• Fellow of the Society for Cardiological Science and Technology
• Associate Fellow of the Academy for Healthcare Science

External Roles

• External Examiner – Manchester University (DProf Healthcare Science)
• External Examiner - Plymouth University (PG Cert Clinical Echocardiography)
• Academic Member, National School of Healthcare Science Quality and Standards Committee
• Reviewer - 'Ultrasound' - Journal of the British Medical Ultrasound Society 

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Degree Programme Director - MSc Clinical Science (Physiological Sciences & Medical Physics)

Programme Director - Postgraduate Certificate Clinical Echocardiography

Board of Studies Chair - MSc Clinical Science

Module Leader

CVR8001 - Introduction to Cardiac Science

CVR8009 - Diagnosis and Management of Cardiac Rhythm Disorders

TTE8000 - Introduction to Echocardiography

Module Contributor

CVR8004 - Clinical Assessment & Investigations

CVR8007 - Diagnostic Approaches & Current Treatment of Cardiovascular Disorders

CVR8008 - Ultrasound Imaging in Cardiac Disease

TTE8001 - Ultrasound Imaging in Cardiac Disease

PSC2020 - Neural and hormonal control of the cardiovascular system ( 3 lectures / 1 seminar)

MSC8001 - Overview of cardiovascular and nervous system for Medical Physics students (2 lectures)

SPE1015 - Overview of cardiovascular system for Speech & Language Therapy students (2 lectures)

SES1000 - Blood (lecture) and Cardiac Function workshop

MBBS - MBBS Cardiac Physiology Tutorials and Cardiac Imaging workshop

MRes in Cardiovascular Science in Health and Disease (1 lecture)

Current projects

PhD Supervisor - Peter Luke (The Assessment of Cardiac Work in Severe Aortic Stenosis)

Providing echocardiographer expertise to SILIcoFCM trial investigating clinical and genetic determinants of disease progression and response to lifestyle interventions in patients with hypertrophic cardiomyopathy.  [Principal Investigator: Dr Djordje Jakovljevic].

Past projects

Providing echocardiographer expertise to a NIHR Newcastle Biomedical Research Centre for Chronic and/or Rare Diseases project:  Personalised home-based physical activity intervention in older adults with Heart Failure: advancing towards an effective clinical therapy  [Principal Investigator: Dr Djordje Jakovljevic].   

Providing echocardiography expertise for the RELAX trial ( A multicenter, randomized, double-blind, crossover placebo-controlled Phase II study to assess the effect of serelaxin versus placebo on high-sensitivity cardiac troponin I (hs-cTnI) release in patients with chronic heart failure after exercise when used in addition to standard of care)  [Principal Investigator: Dr Matthew Bates].   

• Articles

  • Alyahya AI, Charman SJ, Okwose NC, Fuller AS, Eggett C, Luke P, Bailey K, MacGowan GA, Jakovljevic DG. Heart rate variability and haemodynamic function in individuals with hypertrophic cardiomyopathy. Clinical Physiology and Functional Imaging 2023, 43(6), 421-430.
  • Fuller A, Okwose N, Scragg J, Eggett C, Luke P, Bandali A, Velicki R, Greaves L, MacGowan GA, Jakovljevic DG. The effect of age on mechanisms of exercise tolerance: Reduced arteriovenous oxygen difference causes lower oxygen consumption in older people. Experimental Gerontology 2021, 149, 111340.
  • Pandhita BAW, Okwose NC, Koshy A, Fernandez OG, Cruz NB, Eggett C, Velicki L, Popovic D, MacGowan GA, Jakovljevic DG. Noninvasive Assessment of Cardiac Output in Advanced Heart Failure and Heart Transplant Candidates Using the Bioreactance Method. Journal of Cardiothoracic and Vascular Anesthesia 2021, 35(6), 1776-1781.
  • Luke P, Booth K, Kindawi A, Eggett C. Type A aortic dissection: Why there is still a role for echocardiography when every second counts. SAGE Open Medical Case Reports 2020, 8.
  • Okwose NC, Zhang J, Chowdhury S, Houghton D, Ninkovic S, Jakovljevic S, Jevtic B, Ropret R, Eggett C, Bates M, MacGowan G, Jakovljevic D. Reproducibility of Inert Gas Rebreathing Method to Estimate Cardiac Output at Rest and During Cardiopulmonary Exercise Stress Testing. International Journal of Sports Medicine 2019, 40(2), 125-132.
  • Nathania M, Hollingsworth KG, Bates M, Eggett C, Trenell MI, Velicki L, Seferovic PM, MacGowan GA, Turnbull DM, Jakovljevic DG. Impact of age on the association between cardiac high-energy phosphate metabolism and cardiac power in women. Heart 2018, 104(2), 111-118.
  • Okwose NC, Chowdhury S, Houghton D, Trenell MI, Eggett C, Bates M, Macgowan GA, Jakovljevic DG. Comparison of cardiac output estimates by bioreactance and inert gas rebreathing methods during cardiopulmonary exercise testing. Clinical Physiology and Functional Imaging 2018, 38(3), 483-490.
  • Richley D, Eggett CJ. Advanced Techniques in ECG. British Journal of Cardiac Nursing 2018, 13(9), 440-445.
  • Luke P, Eggett C, Spyridopoulos I, Irvine T. A comparative analysis of British and American Society of Echocardiography recommendations for the assessment of left ventricular diastolic function. Echo Research and Practice 2018, 5(4), 139-147.
  • McCoy J, Bates M, Eggett C, Siervo M, Cassidy S, Newman J, Moore SA, Gorman G, Trenell MI, Velicki L, Seferovic PM, Cleland JGF, MacGowan GA, Turnbull DM, Jakovljevic DG. Pathophysiology of exercise intolerance in chronic diseases: the role of diminished cardiac performance in mitochondrial and heart failure patients. Open Heart 2017, 4, e000632.
  • Perkins RE, Hollingsworth KG, Eggett C, MacGowan GA, Bates MG, Trenell MI, Jakovljevic DG. Relationship between bioreactance and magnetic resonance imaging stroke volumes. British Journal of Anaesthesia 2016, 117(1), 134-136.
  • Njemanze H, Warren C, Eggett C, MacGowan GA, Bates MGD, Siervo M, Ivkovic S, Trenell MI, Jakovljevic DG. Age-related decline in cardiac autonomic function is not attenuated with increased physical activity. Oncotarget 2016, 7(47), 76390-76397.
  • Eggett CJ. Demystifying the cardiac action potential for nurses. British Journal of Cardiac Nursing 2015, 10(3), 140-144.
  • Richley D, Wolff A, Eggett C, Ashton J, Corrigan J. ECG recording in primary care:is it done correctly?. Primary Care Cardiovascular Journal 2013, 6(1), 25-27.
  • Cookson MR, Menzies FM, Manning P, Eggett CJ, Figlewicz DA, McNeil CJ, Shaw PJ. Cu/Zn superoxide dismutase (SOD1) mutations associated with familial amyotrophic lateral sclerosis (ALS) affect cellular free radical release in the presence of oxidative stress. Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders 2002, 3(2), 75-85.
  • Manning P, Cookson MR, Eggett CJ, Tolias CM, Read SJ, Hunter AJ, Tsatmali M, Thody AJ, Hillhouse EW, Shaw PJ, Mcneil CJ. Real-time measurement of free radical production using specific electrochemical sensors: New insight into the consequences of O2/- and NO flux. Analusis 2000, 28(6), 493-505.
  • Shaw PJ, Eggett CJ. Molecular factors underlying selective vulnerability of motor neurons to neurodegeneration in amyotrophic lateral sclerosis. Journal of Neurology 2000, 247((supp.1)), 117-127.
  • Eggett CJ, Crosier S, Manning P, Cookson MR, Menzies FM, McNeil CJ, Shaw PJ. Development and characterisation of a glutamate-sensitive motor neurone cell line. Journal of Neurochemistry 2000, 74(5), 1895-1902.
  • Eggett CJ, Crosier S, Manning P, Cookson MR, Menzies FM, McNeil CJ, Shaw PJ. Development and characterisation of a glutamate-sensitive motor neurone cell line. Journal of Neurochemistry 2000, 74(5), 1895-1902.
  • Shaw PJ, Williams TL, Slade JY, Eggett CJ, Ince PG. Low expression of GluR2 AMPA receptor subunit protein by human motor neurons. NeuroReport 1999, 10(2), 261-265.

• Book Chapters

  • Gu SZ, Gamal A, Eggett C, Ali H, Zaman A, Edwards R, Kunadian V. Percutaneous Coronary Intervention for Left Ventricular Systolic Dysfunction. In: Myat, A; Clarke, S; Curzen, N; Windecker, S; Gurbel, P, ed. The Interventional Cardiology Training Manual. Cham: Springer, 2018, pp.263-274.
  • Beska B, Eggett C, Kunadian V. Mitral Valvuloplasty for Mitral Stenosis. In: Patrizia Presbitero, Julinda Mehilli, Anna Sonia Petronio, ed. Percutaneous Treatment of Cardiovascular Diseases in Women. Springer, 2016, pp.127-13.

• Conference Proceedings (inc. Abstracts)

  • Duan W, Zheng D, Eggett C, Langley P, Murray A. Development of Techniques for Measurement of Left Ventricular Ejection Time. In: Computing in Cardiology Conference (CinC). 2014, Cambridge, MA: IEEE.
  • Duan W, Zheng D, Eggett C, Langley P, Murray A. Relationship between Cardiac Imaging Data and Simultaneous Physiological Measurements. In: Computing in Cardiology 2013. 2013, Zaragoza, Spain: IEEE.
  • Manning P, Cookson MR, Eggett CJ, Hunter AJ, Reed SJ, Shaw PJ, McNeil CJ. Real-time bioelectrochemical investigation of free radical flux in cellular models of pathology. In: 6th World Congress on Biosensors, San Diego. 2000.
  • Manning P, Cookson MR, Eggett CJ, Hunter AJ, Reed SJ, Shaw PJ, McNeil CJ. Real-time bioelectrochemical investigation of brain injury and neurodegeneration. In: Sensors for Brain Mapping 2000. 2000, Lund, Sweden.
  • Manning P, Cookson MR, Eggett CJ, Hunter AJ, Reed SJ, Shaw PJ, McNeil CJ. Real-time bioelectrochemical investigation of brain injury and neurodegeneration. 2000.
  • Eggett CJ, Crosier S, Cookson MR, Manning P, McNeil CJ, Shaw PJ. Motor neurones differ from cortical neurones in their response to AMPA stimulation: Furthering our understanding of selective vulnerability in motor neurone disease. In: EUROPEAN JOURNAL OF NEUROSCIENCE. 2000.
  • Menzies FM, Cookson MR, Manning P, Eggett CJ, Tomkins J, Illingworth J, Dong L, Figlewicz DA, McNeill CJ, Shaw PJ. Mechanisms leading to cell death associated with mutations in Cu/Zn superoxide dismutase (SOD1): Insights from cellular models. In: EUROPEAN JOURNAL OF NEUROSCIENCE. 2000.

• Editorial

  • Eggett C. Innovative technologies for the cardiac patient and their effects. British Journal of Cardiac Nursing 2015, 10(8), 370-370.

• Review

  • Ince PG, Eggett CJ, Shaw PJ. The role of excitotoxicity in neurological disease. Reviews in Contemporary Pharmacotherapy 1997, 8(4), 195-212.