Staff Profile
Dr Steven Masson
Associate Clinical Lecturer
- Email: steven.masson@ncl.ac.uk
- Telephone: 0191 244 8567
- Address: Liver Unit,
Freeman Hospital,
Newcastle upon Tyne,
NE7 7DN
Background
Area of expertise
- Hepatology
- Liver disease
- Liver transplant
- Alcohol
- Haemochromatosis
- Viral Hepatitis
Publications
- Forrest EH, Atkinson SR, Richardson P, Masson S, Ryder S, Thursz MR, Allison M. Application of prognostic scores in the STOPAH trial: Discriminant function is no longer the optimal scoring system in alcoholic hepatitis. Journal of Hepatology 2018, 68(3), 511-518.
- Whitfield JB, Masson S, Liangpunsakul S, Hyman J, Mueller S, Aithal G, Eyer F, Gleeson D, Thompson A, Stickel F, Soyka M, Daly AK, Cordell HJ, Liang T, Foroud T, Lumeng L, Pirmohamed M, Nalpas B, Bence C, Jacquet J-M, Louvet A, Moirand R, Nahon P, Naveau S, Perney P, Podevin P, Haber PS, Seitz HK, Day CP, Mathurin P, Morgan TM, Seth D. Evaluation of laboratory tests for cirrhosis and for alcohol use, in the context of alcoholic cirrhosis. Alcohol 2018, 66, 1-7.
- Boyle M, Masson S, Anstee QM. The bidirectional impacts of alcohol consumption and the metabolic syndrome: Cofactors for progressive fatty liver disease. Journal of Hepatology 2018, 68(2), 251-267.
- Houghton D, Hallsworth K, Thoma C, Cassidy S, Hardy T, Heaps S, Hollingsworth KG, Taylor R, Day CP, Masson S, McPherson S, Anstee QM, Trenell MI. Effects of Exercise on Liver Fat and Metabolism in Alcohol Drinkers. Clinical Gastroenterology and Hepatology 2017, 15(10), 1596-1603.e3.
- Vergis N, Atkinson SR, Knapp S, Maurice J, Allison M, Austin A, Forrest EH, Masson S, McCune A, Patch D, Richardson P, Gleeson D, Ryder SD, Wright M, Thursz MR. In Patients With Severe Alcoholic Hepatitis, Prednisolone Increases Susceptibility to Infection and Infection-Related Mortality, and Is Associated With High Circulating Levels of Bacterial DNA. Gastroenterology 2017, 152(5), 1068-1077.e4.
- Hardy T, Zeybel M, Day CP, Dipper C, Masson S, McPherson S, Henderson E, Tiniakos D, White S, French J, Mann DA, Anstee QM, Mann J. Plasma DNA methylation: A potential biomarker for stratification of liver fibrosis in non-alcoholic fatty liver disease. Gut 2017, 66(7), 1321-1328.
- Barbier-Torres L, Iruzubieta P, Fernández-Ramos D, Delgado TC, Taibo D, Guitiérrez-de-Juan V, Varela-Rey M, Azkargorta M, Navasa N, Fernández-Tussy P, Zubiete-Franco I, Simon J, Lopitz-Otsoa F, Lachiondo-Ortega S, Crespo J, Masson S, McCain MV, Villa E, Reeves H, Elortza F, Lucena MI, Hernández-Alvarez MI, Zorzano A, Andrade RJ, Lu SC, Mato JM, Anguita J, Rincon M, Martínez-Chantar ML. The mitochondrial negative regulator MCJ is a therapeutic target for acetaminophen-induced liver injury. Nature Communications 2017, 8, 2068.
- Johnson C, Todd S, McPherson S, Masson S. An Audit of Primary Prophylaxis Against Variceal Bleeding Amongst Patients with Cirrhosis. In: British Society of Gastroenterology Annual General Meeting. 2016, Liverpool: BMJ Publishing Group.
- O'Neill G, Masson S, Bewick L, Doyle J, McGovern R, Stoker E, Wright H, Newbury-Birch D. Can a theoretical framework help to embed alcohol screening and brief interventions in an endoscopy day-unit?. Frontline Gastroenterology 2016, 7(1), 47-53.
- Saunders R, Abou-Beih S, Masson S, Oakley F, Tiniakos D. Evaluation of centrilobular fibrosis in post-transplant liver: Preliminary results. In: 29th European Congress of Pathology. 2016, Amsterdam, Netherlands: Springer.
- Dyson JK, Rajasekhar P, Wetten A, Hamad AH, Ng S, Paremal S, Baqai MF, Lamb CA, Masson S, Hudson M, Dipper C, Cowlam S, Hussaini H, McPherson S. Implementation of a “care bundle” improves the management of patients admitted to hospital with decompensated cirrhosis. Alimentary Pharmacology and Therapeutics 2016, 44(10), 1030–1038.
- Welsh S, Valappil M, Miller C, Robinson E, Price A, Schmid M, Masson S, McPherson S. Increasing Access to Hepatitis C Treatment in The North East of England. In: British Society of Gastroenterology, Annual General Meeting. 2016, Liverpool: BMJ Group.
- Verma S, Hand F, Armstrong MJ, de Vos M, Thorburn D, Pan T, Klinck J, Westbrook RH, Auzinger G, Bathgate A, Masson S, Holt A, Houlihan DD, Ferguson JW. Portopulmonary Hypertension: Still an Appropriate Consideration for Liver Transplantation?. Liver Transplantation 2016, 22(12), 1637-1642.
- Abou-Beih SS, Masson S, Saunders R, Haugk B, Oakley F, Tiniakos D. Sinusoidal and pericellular fibrosis in adult post-transplant liver biopsies: Association with histological changes, hepatic stellate cell activation and impact on patient outcome. In: 67th Annual Meeting of the American Association for the Study of Liver Diseases: The Liver Meeting 2016. 2016, Washington DC: Wiley-Blackwell.
- Whitfield JB, Rahman K, Haber PS, Day CP, Masson S, Daly AK, Cordell HJ, Mueller S, Seitz HK, Liangpunsakul S, Westerhold C, Liang TB, Lumeng L, Foroud T, Nalpas B, Mathurin P, Stickel F, Soyka M, Botwin GJ, Morgan TR, Seth D, GenomALC Consortium. Brief Report: Genetics of Alcoholic Cirrhosis-GenomALC Multinational Study. Alcoholism: Clinical and Experimental Research 2015, 39(5), 836-842.
- Zeybel M, Hardy T, Robinson SM, Fox C, Anstee QM, Ness T, Masson S, Mathers JC, French J, White S, Mann J. Differential DNA methylation of genes involved in fibrosis progression in non-alcoholic fatty liver disease and alcoholic liver disease. Clinical Epigenetics 2015, 7(25).
- Dyson JK, Masson S, McPherson S, Manas DM, Hudson M. Experience of Using Advagraf in a Single Liver Transplant Centre in the United Kingdom. In: ILTS 21st Annual International Congress. 2015, Chicago, Illinois: Lippincott Williams & Wilkins.
- Marrow B, Clarkson J, Chapman CE, Masson S. Facilitation of blood donation amongst haemochromatosis patients. Transfusion Medicine 2015, 25(4), 239-242.
- Dyson JK, Latimer S, Robinson-Smith P, Masson S, McPherson S, Hudson M. Impact of a Nurse-Led Annual Review Clinic for Liver Transplant Recipients. In: ILTS 21st Annual International Congress. 2015, Chicago, Illinois, USA: Lippincott Williams & Wilkins.
- Dyson JK, Latimer S, Robinson-Smith P, McPherson S, Masson S, Hudson M. Importance of Health Education in an Annual Review Liver Transplant Clinic in the United Kingdom. In: ILTS 21st Annual International Congress. 2015, Chicago, Illinois, USA: Lippincott Williams & Wilkins.
- Verma S, Hand FM, Armstrong MJ, de Vos M, Thorburn D, Pan T, Klinck JR, Westbrook R, Auzinger G, Bathgate A, Masson S, Holt A, Houlihan DD, Ferguson JW. Liver Transplantation for Portopulmonary Hypertension (PoPH): Multi-centre UK experience over twenty years. In: 66th Annual Meeting of the American Association for the Study of Liver Diseases: The Liver Meeting 2015. 2015, San Francisco, CA, USA: Wiley.
- Thursz MR, Richardson P, Allison M, Austin A, Bowers M, Day CP, Downs N, Gleeson D, MacGilchrist A, Grant A, Hood S, Masson S, McCune A, Mellor J, O'Grady J, Patch D, Ratcliffe I, Roderick P, Stanton L, Vergis N, Wright M, Ryder S, Forrest EH, STOPAH Trial. Prednisolone or Pentoxifylline for Alcoholic Hepatitis. New England Journal of Medicine 2015, 372(17), 1619-1628.
- Thursz M, Forrest E, Roderick P, Day C, Austin A, O'Grady J, Ryder A, Allison M, Gleeson D, McCune A, Patch D, Wright M, Masson S, Richardson P, Hood S, MacGilchrist A, Grant A, Vale L, Mellor J, Stanton L, Bowers M, Ratcliffe I, Downs N, Kirkman S, Homer T, Ternent L, Deverill M. The clinical effectiveness and cost-effectiveness of STeroids or Pentoxifylline for Alcoholic Hepatitis (STOPAH): a 2x2 factorial, randomised controlled trial. Health Technology Assessment 2015, 19(102).
- John S, Burnell P, Robinson S, Masson S, Sen G, Hudson M, Manas D. Umbilical hernia repair in cirrhosis: outcomes and prognostic factors in a liver transplant unit. In: 2nd Digestive Disorders Federation Conference 2015. 2015, London, UK: BMJ Group.
- Dyson JK, Carter V, Hudson M, Manas DM, Masson S. A Positive Complement Dependent Cytotoxic (CDC) Crossmatch Does Not Impact on Patient Survival or Increase the Risk of Acute Cellular Rejection, or Biliary Strictures after Liver Transplantation. In: British Society of Gastroenterology Annual General Meeting. 2014, Manchester, UK: BMJ Publishing Group.
- Moles A, Murphy L, Wilson CL, Bagchi Chakraborty J, Fox C, Park EJ, Mann J, Oakley F, Howarth R, Brain J, Masson S, Karin M, Seki E, Mann DA. A TLR2/S100A9/CXCL-2 signaling network is necessary for neutrophil recruitment in acute and chronic liver injury in the mouse. Journal of Hepatology 2014, 60(4), 782-791.
- Masson S, Marrow B, Kendrick S, Elsharkawy AM, Latimer S, Hudson M. An 'alcohol contract' has no significant effect on return to drinking after liver transplantation for alcoholic liver disease. Transplant International 2014, 27(5), 475-481.
- Masson S, Emmerson I, Henderson E, Fletcher EH, Burt AD, Day CP, Stewart SF. Clinical but not histological factors predict long-term prognosis in patients with histologically advanced non-decompensated alcoholic liver disease. Liver International 2014, 34(2), 235-242.
- Thursz MR, Richardson P, Allison ME, Austin A, Bowers M, Day CP, Downs N, Gleeson D, MacGilchrist AJ, Grant A, Hood S, Masson S, McCune A, Mellor JM, O'Grady JG, Patch DW, Ratcliffe I, Roderick P, Stanton L, Vergis N, Wright M, Ryder SD, Forrest E. Steroids or Pentoxifylline for Alcoholic Hepatitis: Results of the STOPAH Trial. In: 65th Annual Meeting of the American Association for the Study of Liver Diseases: The Liver Meeting 2014. 2014, Boston, MA, USA: John Wiley & Sons, Inc.
- Hulley JL, Douglass A, White S, Masson S. Benefits of a Liver Transplant Outreach Clinic: Increased Referrals and Patient Satisfaction. In: British Society of Gastroenterology Annual General Meeting. 2013, Glasgow, UK: BMJ Publishing Group.
- Barrie T, Yeung S, Fathima S, Anstee QM, Masson S, Mcpherson S. Does the Pre-Bone Mineral Density Frax Score Predict Fracture Risk in Patients with Cirrhosis?. In: British Society of Gastroenterology Annual General Meeting. 2013, Glasgow, UK: BMJ Publishing Group.
- Elsharkawy AM, Schwab U, McCarron B, Burt AD, Daly AK, Hudson M, Masson S. Efavirenz induced acute liver failure requiring liver transplantation in a slow drug metaboliser. Journal of Clinical Virology 2013, 58(1), 331-333.
- Marrow B, Clarkson J, Chapman C, Masson S. Facilitation of Blood Donation amongst Haemochromatosis Patients: A UK Pilot. In: 48th Annual meeting of the European Association for the Study of the Liver. 2013, Amsterdam, Netherlands: Elsevier BV.
- Orr J, Bury Y, Hudson M, Masson S. Liver transplantation for acute liver failure caused by macrophage activation syndrome. Transplant International 2013, 26(11), e105-e108.
- Forrest E, Mellor J, Stanton L, Bowers M, Ryder P, Austin A, Day C, Gleeson D, O'Grady J, Masson S, McCune A, Patch D, Richardson P, Roderick P, Ryder S, Wright M, Thursz M. Steroids or pentoxifylline for alcoholic hepatitis (STOPAH): study protocol for a randomised controlled trial. Trials 2013, 14, 262.
- Brain J, Masson S, Burt A. Transplantation for ALD: Lessons from the Explant. In: 48th Annual meeting of the European Association for the Study of the Liver. 2013, Amsterdam, Netherlands: Elsevier.
- Hardy T, Wells C, Kendrick S, Hudson M, Day CP, Burt AD, Masson S, Stewart SF. White cell count and platelet count associate with histological alcoholic hepatitis in jaundiced harmful drinkers. BMC Gastroenterology 2013, 13(1), 55.
- Kendrick S, Elsharkawy A, Latimer S, Hudson M, Masson S. An “alcohol contract” has not reduced rates of post-transplant drinking following transplantation for alcoholic liver disease. In: Digestive Disorders Federation Meeting. 2012, Liverpool, UK: BMJ Group.
- Lee TJW, Samuel M, Bewick L, Rutherford H, Perez P, Gilvarry E, Cunningham M, Dipper C, Masson S. Benefits of introduction of a symptom triggered regimen for management of alcohol withdrawal in a large teaching hospital trust: reduced admission duration and cost savings. In: Digestive Disorders Federation Meeting. 2012, Liverpool, UK: BMJ Group.
- Masson S, Emmerson I, Henderson E, Fletcher E, Burt AD, Day CP, Stewart SF. Clinical but not histological factors predict long-term prognosis in patients with biopsy proven advanced alcoholic liver disease. In: 47th Annual Meeting of the European Association for the Study of the Liver (EASL). 2012, Barcelona, Spain: Elsevier BV.
- Masson S, Emmerson I, Henderson E, Fletcher E, Burt A, Day C, Stewart S. Clinical but not histological factors predict long-term prognosis in patients with biopsy proven advanced alcoholic liver disease. In: Digestive Disorders Federation Meeting. 2012, Liverpool, UK: BMJ Group.
- Elsharkawy AM, McPherson S, Masson S, Burt AD, Dawson RT, Hudson M. Lesson of the Week: Cholestasis secondary to anabolic steroid use in young men. British Medical Journal 2012, 344, e468.
- Zeybel M, Hardy T, Wong YK, Mathers JC, Fox CR, Gackowska A, Oakley F, Burt AD, Wilson CL, Anstee QM, Barter MJ, Masson S, Elsharkawy AM, Mann DA, Mann J. Multigenerational epigenetic adaptation of the hepatic wound-healing response. Nature Medicine 2012, 18(9), 1369-U110.
- Kendrick S, Elsharkawy A, Latimer S, Hudson M, Masson S. The effect of an 'alcohol contract' on ethanol consumption after transplantation for alcoholic liver disease. In: 47th Annual Meeting of the European Association for the Study of the Liver (EASL). 2012, Barcelona, Spain: Elsevier BV.
- Kendrick S, Elsharkaway A, Latimer S, Hudson M, Masson S. Transplantation for Alcoholic Liver Disease: Recidivism, Survival and the Effect of an 'Alcohol Contract'. In: 18th Annual International Congress on ILTS. 2012, San Francisco, California, USA: John Wiley & Sons, Inc.
- Masson S, Mardini HA, Rose JD, Record CO. Hepatic encephalopathy after transjugular intrahepatic portosystemic shunt insertion: A decade of experience. QJM 2008, 101(6), 493-501.
- Masson S, Chinn DJ, Tabaqchali MA, Waddup G, Dwarakanath AD. Is anaemia relevant in the referral and diagnosis of colorectal cancer?. Colorectal Disease 2007, 9(8), 736-739.
- Masson S, Mardini HA, Rose JD, Record CO. Minimal hepatic encephalopathy after tips insertion is associated with a reduced quality of life. Gut 2007, 56, A128-A129.
- Weatherhead M, Masson S, Bourke SJ, Gunn MC, Burns GP. Interstitial pneumonitis after infliximab therapy for Crohn's disease. Inflammatory Bowel Diseases 2006, 12(5), 427-428.
- Masson S, Harrison DJ, Plevris JN, Newsome PN. Potential of hematopoietic stem cell therapy in hepatology: A critical review. Stem Cells 2004, 22(6), 897-907.
- Newsome PN, Tsiaoussis J, Masson S, Buttery R, Livingston C, Ansell I, Ross JA, Sethi T, Hayes PC, Plevris JN. Serum from patients with fulminant hepatic failure causes hepatocyte detachment and apoptosis by a beta(1)-integrin pathway. Hepatology 2004, 40(3), 636-645.
- Forrest EH, Atkinson SR, Richardson P, Masson S, Ryder S, Thursz MR, Allison M. ACG Clinical Guideline for Alcoholic Liver Disease: The MELD Threshold for Corticosteroid Treatment has Yet to be Established. American Journal of Gastroenterology 2019, 114(1), 175-176.
- Forrest EH, Atkinson SR, Richardson P, Masson S, Ryder S, Thursz MR, Allison M. Reply to: “The long-term prognosis of alcoholic hepatitis is poor and independent of disease severity for patients surviving an acute episode”. Journal of Hepatology 2018, 68(6), 1332-1332.