Staff Profile
Dr Niraj Prasad
Research Associate
- Email: niraj.prasad@ncl.ac.uk
- Address: Office D.11A
School of Mathematics, Statistics and Physics
Herschel Building
Newcastle University
Newcastle upon Tyne
NE1 7RU
UK
Hello, I am a postdoctoral research associate at Newcastle University. Before that, I completed my PhD from the Indian Institute of Technology Guwahati. As an Experimental Fluid Dynamist, I explore patterns in the fluid motion ranging across broad length scales from internal solitary waves in oceans to microfluidic particles in biomedical systems. I also explore the computational methods to capture the dynamics of complex flows that theory alone cannot predict. I like hiking, camping, and motorcycle rides in the Himalayas.
My work as a postdoctoral research associate primarily involves experimental and computational investigation of mode-2 internal solitary waves (ISWs). So far, limited mathematical investigations have been made of multi-humped mode-2 waves. Thus I started performing experimental and numerical studies to investigate the physical generation of these exotic waves. For this, I developed expertise in generating internal solitary waves within a wave flume filled with triple stratified layers of water. I also developed a numerical model to mimic the experimental setup and generated the multi- humped waves using an open source solver, Spectral Parallel Incompressible Navier-Stokes solver (SPINS) .
During my Ph.D., much of my research involved designing an experimental and multiphase computational model for deciphering flow dynamics and deformation of drug carriers and cancer cells flowing through microchannels of minimum width 7 μm. Another significant portion of my research included fabricating constricted microchannels that mimic the confinement of blood capillary networks. In my research, I learned to operate sophisticated instruments like Mask Writer for fabricating microfluidic patterns on the silicon wafer, and conductivity probes for measuring the stratification of three-layer fluid in wave flume. In doing so, I got trained in handling equipment inside cleanroom. Additionally, I synthesized and characterized drug carriers such as hydrogels and nanovesicles for my experimental work and did high-speed visualization of the flow of these carriers via constricted microchannel. While performing experiments, I was trained in handling high-speed cameras, and gained elementary proficiency in instruments like Dynamic Light Scattering, Zetasizer, Flow Cytometry, and FESEM. My research also involved creating a two-phase viscoelastic drop model for these cells and carriers. The multiphase viscoelastic drop model was created to understand these drug carriers’ elastic and shear-thinning behavior, which is somewhat difficult to discern through experiments. I used a finite volume-based open-source solver Basilisk to simulate the two-phase Newtonian viscoelastic drop-matrix system. Furthermore, I was trained in open-source platforms like Matplotlib (Python), Image J and commercial software like Tecplot, Matlab for post-processing of the results obtained from experimental and numerical investigations. In addition, I helped expand my lab’s experimental capabilities to create PDMS-based microchannels. Furthermore, I also trained my colleagues to operate KLOE DILASE 250 Mask Writer for fabricating microchannel patterns on silicon wafers.
- Teaching Assistant for the course Computational Fluid Dynamics for Incompressible Flows and Fundamentals of Convective Heat Transfer by National Programme on Technology Enhanced Learning (NPTEL), IIT Guwahati (2020 - 2024)
- Teaching Assistant for the course Fundamentals of Conduction and Radiation by National Programme on Technology Enhanced Learning (NPTEL), IIT Guwahati (July - October, 2019 & 2022)
- Assistant Professor in the Department of Mechanical Engineering in Dr. A.P.J. Abdul Kalam Technical University Uttar Pradesh, India (2017-2018)
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Articles
- Prasad, NK, Arora, A, Ghosh, SS, Dalal, A. An Advanced Microfluidic Platform for Assessment of DOX Uptake by MCF-7 Cells Inside Microenvironment Mimicking Blood Capillary Networks. SSRN 2025, 27.
- Srikara VS, Prasad NK, Dalal A. A computational model for studying drug release by drug carrier flowing through constricted channel. Physics of Fluids 2025, 37(7), 073124.
- Neogi A, Prasad NK, Ghosh SS, Dalal A. A computational model for complete separation of circulating tumor cells inside grooved microchannel under the effect of dielectrophoretic forces. Physics of Fluids 2025, 37(5), 051901.
- Prasad NK, Ghosh SS, Dalal A. Understanding Deformation and Breakup Tendency of Shear-Thinning Viscoelastic Drops in Constricted Microchannels. Langmuir 2023, 39(34), 11975-11991.
- Agnihotry A, Prasad NK, Dalal A. Numerical study of bubble rise in a three-dimensional sinusoidal channel. Physics of Fluids 2023, 35(9), 092109.
- Prasad NK, Shome R, Biswas G, Ghosh SS, Dalal A. Transport Behavior of Commercial Anticancer Drug Protein-Bound Paclitaxel (Paclicad) in a Micron-Sized Channe. Langmuir 2022, 38(6), 2014-2025.
- Prasad NK, Shome R, Biswas G, Ghosh SS, Dalal A. Discerning the self-healing, shear-thinning characteristics and therapeutic efficacy of hydrogel drug carriers migrating through constricted microchannel resembling blood microcapillary. Colloids and Surfaces A: Physicochemical and Engineering Aspects 2021, 626, 127070.