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Personalised Medicine, Genomics & Informatics

Using multi-dimensional data to improve treatments and outcomes for cancer patients.

Precision medicine is the term given to current concepts of optimal delivery of health care to individuals and populations — personalised cancer medicine.

We aim to exploit multidimensional clinical, genetic, pathological, and molecular data. We do this to improve treatments and outcomes for cancer patients.

We work closely with NHS partners to deliver personalised cancer medicine. This enables advances to be translated into patient benefit quickly and efficiently. Example advances are:

  • including biomarkers for tailored cancer treatment
  • pharmacogenomic stratification to
    • optimise drug efficacy
    • improve the safety of chemotherapy and radiotherapy.

Precision medicine has had a great impact in oncology. Stratified approaches to cancer therapy are now part of routine clinical care for cancer patients across all age groups.

Personalised Medicine

Adult cancers

Our work in adult cancers such is being used to develop:

  • novel screening assays
  • prognosticion models
  • treatments to enhance both cancer prevention and patient management

We are developing these approaches for:

  • hepatocellular carcinoma
  • urological cancer
  • colorectal cancer
  • haematological cancers
  • melanoma
  • sarcoma
  • gastric and gynaecological cancer
Personalised Medicine

Paediatric cancers

We also have a strong international reputation in personalised cancer medicine of paediatric cancers including:

  • medulloblastoma
  • neuroblastoma
  • leukaemia
  • lymphoma

Our work on molecular classification is tailoring treatment, improving outcomes, and reducing late-effects.

Personalised Medicine

The importance of data

Fundamental to success in precision oncology is the ability to generate data. We integrate and mine complex data sets using the expertise we have in bioinformatics and high performance computing.

Data comes from a range of methodologies and platforms including:

  • cytogenetics
  • genetics
  • pharmacogenomics
  • toxicology
  • computational pathology

Find out more about our University's work in Precision Medicine, Genomics and Informatics

Personalised Medicine