Staff Profile

NIHR Newcastle Biomedical Research Centre Theme Lead, Precision Medicine, Genomics and Informatics

• Use of routinely collected data for research in multiple long-term conditions
• Development of clinical decision support tools to aid precision medicine delivery in clinical practice

Chief Clinical Information Officer, The Newcastle upon Tyne Hospitals NHS Foundation Trust

• Clinical lead for digital systems across the Trust and Great North Care Record

Consultant Cardiologist, The Newcastle upon Tyne Hospitals NHS Foundation Trust

• Clinical lead for cardio-oncology, MRI in patients with Cardiac Implanted Electronic Devices and co-lead for device lead extraction

Chair European Examination in Core Cardiology Board (2017 to date)

Vice President European Union of Medical Specialists Cardiology Section (2017 to date)

Member European Society of Cardiology Education Committee (2020 to date)

Member British Cardiovascular Society Council (2019 to date)

Nucleus Member European Society of Cardiology Council of Cardio-Oncology (2020 to date)

UK Representative European Union of Medical Specialists Cardiology Section (2017 to date)

European Examination in Core Cardiology question writing committee member (2008 to date)

Secretary British Cardio-Oncology Society (2012 to 2022)

Northern Region Cardiology Training Programme Director (2012-2016)

Cardiology ARCP chair Northern Deanery (2007-2012)

UK Cardiology Specialty Advisory Committee representative for ePortfolio and UEMS collaboration (2016 to date)

Medical student interviewer – Newcastle University (2002 to date)

Foundations of clinical practice course teacher (2002 to date)

MSc Clinical Science (Physiological Sciences - Cardiac Science) (2014 to date)

• Articles

  • Weiand D, Cullerton C, Oxley R, Plummer CJ. Impact of computerised provider order entry on the quality and quantity of clinical information included with investigation requests: an interrupted time series analysis. BMJ Open Quality 2023, 12(1), e002143.
  • Halford S, Veal GJ, Wedge SR, Payne GS, Bacon CM, Sloan P, Dragoni I, Heinzmann K, Potter S, Salisbury BM, Chenard-Poirier M, Greystoke A, Howell EC, Innes WA, Morris K, Plummer C, Rata M, Petrides G, Keun HC, Banerji U, Plummer R. A phase I dose-escalation study of AZD3965, an oral monocarboxylate transporter 1 inhibitor, in patients with advanced cancer. Clinical Cancer Research 2023, 29(8), 1429-1439.
  • van Dalen EC, Mulder RL, Suh E, Ehrhardt MJ, Aune GJ, Bardi E, Benson BJ, Bergler-Klein J, Chen MH, Frey E, Hennewig U, Lockwood L, Martinsson U, Muraca M, van der Pal H, Plummer C, Scheinemann K, Schindera C, Tonorezos ES, Wallace WH, Constine LS, Skinner R, Hudson MM, Kremer LCM, Levitt G, Mulrooney DA. Coronary artery disease surveillance among childhood, adolescent and young adult cancer survivors: A systematic review and recommendations from the International Late Effects of Childhood Cancer Guideline Harmonization Group. European Journal of Cancer 2021, 156, 127-137.
  • Earl H, Hiller L, Vallier A-L, Loi S, McAdam K, Hughes-Davies L, Rea D, Howe D, Raynes K, Higgins HB, Wilcox M, Plummer C, Mahler-Araujo B, Provenzano E, Chhabra A, Gasson S, Balmer C, Abraham JE, Caldas C, Hall P, Shinkins B, McCabe C, Hulme C, Miles D, Wardley AM, Cameron DA, Dunn JA. Six versus 12 months’ adjuvant trastuzumab in patients with HER2-positive early breast cancer: The PERSEPHONE non-inferiority RCT. Health Technology Assessment 2020, 24(40), 1-230.
  • Findlay SG, Gill JH, Plummer R, De-Santis C, Plummer C. Chronic cardiovascular toxicity in the older oncology patient population. Journal of Geriatric Oncology 2019, 10(5), P685-689.
  • Earl HM, Hiller L, Vallier A-L, Loi S, McAdam K, Hughes-Davies L, Harnett AN, Ah-See M-L, Simcock R, Rea D, Raj S, Woodings P, Harries M, Howe D, Raynes K, Higgins HB, Wilcox M, Plummer C, Mansi J, Gounaris I, Mahler-Araujo B, Provenzano E, Chhabra A, Abraham JE, Caldas C, Hall PS, McCabe C, Hulme C, Miles D, Wardley AM, Cameron DA, Dunn JA, Agarwal R, Algurafi H, Allerton R, Archer C, Armstrong A, Bale C, Barraclough L, Barthakur U, Bedi C, Benstead K, Bloomfield D, Bowen R, Bradley C, Brown J, Butt M, Churn M, Cleator S, Cliff J, Crellin P, Daly M, De Silva-Minor S, Dhadda A, Din O, Down S, Earl H, Eaton D, Eichholz A, Epurescu D, Goh C, Goodman A, Grieve R, Hadaki M, Harper-Wynne C, Hayward L, Humphreys A, Innes H, Jafri M, Jegannathen A, Kelleher M, Kristeleit H, Lee D, Lupton S, MacGregor C, Malik Z, Marshall J, McGolick T, Mehra R, Mithal N, Moss C, Moss A, Mukesh M, Neal A, Nelmes D, Neville-Webbe H, Newby J, O'Reilly S, Ostler P, Persic M, Pettit L, Raja F, Reed C, Rigg A, Roe H, Shah N, Simmonds P, Sims E, Smith S, Storey N, Taylor W, Thanvi N, Tipples K, Vaidya J, Varughese M, Vinayan A, Walji N, Waters S, Wright K, Yahya S. 6 versus 12 months of adjuvant trastuzumab for HER2-positive early breast cancer (PERSEPHONE): 4-year disease-free survival results of a randomised phase 3 non-inferiority trial. The Lancet 2019, 393(10191), 2599-2612.
  • Plummer CJ, Frank CM, Bari Z, Al Hebaishi YS, Klepfer RN, Stadler RW, Ghosh S, Liu S, Mittal S. A novel algorithm increases the delivery of effective cardiac resynchronization therapy during atrial fibrillation: The CRTee randomized crossover trial. Heart Rhythm 2018, 15(3), 369-375.
  • Mealing S, Woods B, Hawkins N, Cowie MR, Plummer CJ, Abraham WT, Beshai JF, Klein H, Sculpher M. Cost-effectiveness of implantable cardiac devices in patients with systolic heart failure. Heart 2016, 102(21), 1742-1749.
  • Raju D, Roysam C, Singh R, Clark SC, Plummer C. Unusual cause of hypoxemia after automatic implantable cardioverter-defibrillatorleads extraction. Annals of Cardiac Anaesthesia 2015, 18(4), 599-602.
  • Woods B, Hawkins N, Mealing S, Sutton A, Abraham WT, Beshai JF, Klein H, Sculpher M, Plummer CJ, Cowie MR. Individual patient data network meta-analysis of mortality effects of implantable cardiac devices. Heart 2015, 101(22), 1800-1806.
  • Fazal IA, Shepherd EJ, Tynan M, Plummer CJ, McComb JM. Comparison of Sprint Fidelis and Riata defibrillator lead failure rates. International Journal of Cardiology 2013, 168(2), 848-852.
  • Okines AFC, Langley RE, Thompson LC, Stenning SP, Stevenson L, Falk S, Seymour M, Coxon F, Middleton GW, Smith D, Evans L, Slater S, Waters J, Ford D, Hall M, Iveson TJ, Petty RD, Plummer C, Allum WH, Blazeby JM, Griffin M, Cunningham D. Bevacizumab with peri-operative epirubicin, cisplatin and capecitabine (ECX) in localised gastro-oesophageal adenocarcinoma: a safety report. Annals of Oncology 2013, 24(3), 702-709.
  • Smith LA, Cornelius VR, Plummer CJ, Levitt G, Verrill M, Canney P, Jones A. Cardiotoxicity of anthracycline agents for the treatment of cancer: Systematic review and meta-analysis of randomised controlled trials. BMC Cancer 2010, 10(1), 337.
  • McComb J, Plummer C. Recognition of ecg abnormalities associated with atrioventricular conduction defects. Heart 2007, 93(s1), A85-A85.
  • McComb J, Plummer C. Lack of knowledge of pacemaker indications at the front line. Heart 2007, 93, A46-A46.
  • McComb J, Plummer C, Charles R, Cunningham M, Cunningham A. Inequity of access to cardiac pacing: Results of a national survey. Heart 2007, 93, A46-A46.
  • Plummer C, Cunningham A, Cunningham M, Charles R, McComb J. An audit of pacing practice in the 33 cardiac networks serving England and Wales. Heart 2007, 93, A45-A46.
  • Plummer CJ, Irving RJ, McComb JM. The incidence of implantable cardioverter defibrillator indications in patients admitted to all coronary care units in a single district. Europace 2005, 7(3), 266-272.
  • Cunningham AD, Plummer CJ, McComb JM, Lord SW, Cunningham MW, Toussaint JM, Rickards AF. The implantable cardioverter-defibrillator: postcode prescribing in the UK 1998-2002. Heart 2005, 91(10), 1280-1283.
  • Plummer CJ, Irving RJ, McComb JM. Implications of national guidance for implantable cardioverter deibrillation implantation in the United Kingdom. Pacing and Clinical Electrophysiology 2003, 26(1, Part 2), 479-482.
  • Plummer CJ, McComb JM. Detection of atrial fibrillation by permanent pacemakers: observations from the STOP AF trial. Cardiac Electrophysiology Review 2003, 7(4), 333-340.
  • Plummer CJ, Henderson S, Gardener L, McComb JM. The use of permanent pacemakers in the detection of cardiac arrhythmias. Europace 2001, 3(3), 229-232.
  • Plummer CJ, Parry G, McComb J. Tachy-brady syndrome six years after cardiac transplantation. HeartWeb 1999, 4(10), U19-U23.

• Conference Proceedings (inc. Abstracts)

  • Fazal IA, Tynan M, Plummer CJ, Mccomb JM. Remote vs. conventional follow-up of implantable loop recorders; time to diagnosis and overall diagnostic yield is similar. In: ESC Congress 2014. 2014, Barcelona, Spain: Oxford University Press.
  • Matthews IG, Plummer CJ, Parry SW. Positive versus Negative Adenosine Tests in Unexplained Syncope Presenting to Acute Medical Services. In: British Geriatrics Society Spring Meeting. 2013, Belfast, Ireland: Oxford University Press.
  • Haney S, Cresti N, Verrill M, Plummer CJ. Cardiac troponin release following standard dose anthracycline-based adjuvant chemotherapy. In: European Society of Cardiology (ESC) Congress 2013. 2013, Amsterdam, Netherlands: Oxford University Press.
  • Fazal IA, Bhardwaj R, Tynan M, Plummer CJ, Mccomb JM. Remote monitoring of implantable loop recorders: high artefact in the early phase following implant. In: ESC Congress. 2012, Munchen, Germany: Oxford University Press.
  • Jones AL, Verrill M, Barrett-Lee P, Canney P, Wardley A, Barlow M, Robb S, Plummer C, Gilmour I. DEVELOPMENT AND IMPLEMENTATION OF NEW UK NATIONAL CANCER RESEARCH INSTITUTE (NCRI) GUIDELINES FOR PREVENTING AND MANAGING CARDIAC EVENTS WITH TRASTUZUMAB. In: 33rd European Society for Medical Oncology Congress. 2008, Stockholm, Sweden: Oxford University Press.
  • Cunnington M, Plummer C, McDiarmid A, McComb J. Delays to permanent pacemaker implantation: An explanation for low implantation rates in the United Kingdom?. In: Annual Scientific Conference of the British Cardiovascular Society. 2007, Glasgow: Heart, BMJ Group.
  • McComb JM, Plummer CJ, Charles RG, Cunningham MW, Cunningham AD. Inequity of access to pacemaker implantation for bradycardia in England. In: World Congress of Cardiology. 2006, Barcelona, Spain: European Heart Journal: Oxford University Press.
  • Plummer CJ, Cunningham AD. Implications of national guidance on pacing mode in the UK. In: World Congress of Cardiology. 2006, Barcelona, Spain: European Heart Journal: Oxford University Press.
  • Shepherd E, Tynan M, Plummer C, Zaman A, Lord S, McComb J. Mortality and symptom benefit with cardiac resynchronisation therapy (CRT) in severe heart failure. In: Heart: Annual Conference of the British Cardiac Society. 2004, Manchester, UK: BMJ Group.
  • Plummer CJ, Kieswetter C, Nath S, McComb JM. Impact of nice guidance on implantable cardioverter defibrillator (ICD) implantation an audit of ICD indications in a tertiary centre and a district hospital. In: Heart: Annual Scientific Conference of the British Cardiac Society. 2003, Glasgow, UK: BMJ Group.
  • Plummer CJ, Tynan M, McComb JM, Bexton RS. Impact of district hospital pacing centres on regional pacemaker implantation rates. In: Heart: Annual Scientific Conference of the British Cardiac Society. 2003, Glasgow, UK: BMJ Group.
  • Plummer CJ, Irving RJ, McComb JM. Implications of national guidance on the implantation of implantable cardioverter-defibrillators for arrhythmias. In: European Heart Journal: Congress of the European Society of Cardiology. 2002, Berlin, Germany: Oxford University Press.
  • Plummer CJ, McComb JM. Audit of potential implantable cardioverter defibrillator patients. In: European Heart Journal. 2001, Oxford University Press.
  • Plummer CJ, Furniss SS, Heslop PS, Walker DJ. Objective assessment of activity in heart disease. In: HEART. 1996.

• Editorials

  • Plummer CJ. What's in the CARDS?. Diabetic Medicine 2006, 23(7), 711-714.
  • Plummer CJ, McComb JM. An audit of the implications of implementing NICE guidance on the use of implantable cardioverter-defibrillators. Heart 2003, 89(7), 787-788.

• Letters

  • Rajan N, Brown S, Ward S, Hainsworth P, Hodgkinson P, Pieniazek P, Husain A, Plummer R. Mesenteric cysts in naevoid basal cell carcinoma syndrome: A mimic of metastatic disease. British Journal of Dermatology 2016, 174(3), 684-685.
  • Doherty L, Kumar P, Bexton R, Plummer C, Dark J, Black F, Lordan J. Aortic regurgitation and Churg-Strauss syndrome. QJM: An International Journal of Medicine 2005, 98(10), 772-773.

• Notes

  • Ooues G, Plummer C, Hall J, Lawson C, Price S, Smith R, Wilson I, Wright R, Bowater S. How to succeed in the EEGC: A guide for trainees and their trainers. Heart 2019, 105(13), 1044-1045.
  • Plummer C, Bowater S, Hall J, Lawson C, Ooues G, Price S, Smith R, Wilson I, Wright R. Behind the scenes of the European Examination in General Cardiology. Heart 2019, 105(11), 889-890.

• Reviews

  • Lowe MD, Plummer CJ, Manisty CH, Linker NJ. Safe use of MRI in people with cardiac implantable electronic devices. Heart 2015, 101(24), 1950-1953.
  • Barrett-Lee PJ, Dixon JM, Farrell C, Jones A, Leonard R, Murray N, Palmieri C, Plummer CJ, Stanley A, Verrill MW. Expert opinion on the use of anthracyclines in patients with advanced breast cancer at cardiac risk. Annals of Oncology 2009, 20(5), 816-827.