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Our Impact

See how our high-quality academic work is benefitting people across the globe.

Changing the world for the better

  • A new technique to prevent transmission of mitochondrial disease 
  • Approval of eculizumab and establishment of a national service to treat patients with Atypical Haemolytic Uraemic Syndrome
  • Ataluren: the first approved oral treatment for Duchenne muscular dystrophy
  • Human-derived limbal cell transplant to treat chemical burns of the eye
  • Erdafitinib, the first-in-class treatment of bladder cancer
  • Fibrofind, a stable human alternative for testing anti-fibrotic drugs
  • Aspirin to decrease the risk of colorectal cancer for patients with Lynch syndrome
  • Peptest, a quick and simple test for reflux
  • Skimune, a test for adverse immune reactions to compounds including chemical cosmetics and novel pharmaceuticals
Hyperfused mitochondria and DNA

Spin-out companies

We have an excellent track record for producing spin out companies from applied research with a significant role in the development of new products and services. Spin out companies also contribute to the development and vitality of the region through new jobs and revenue creation. 

Aelius Biotech

Aelius Biotech is a contract research company specialising in modelling the mucosal surfaces of the aerodigestive tract. Aelius' Integrated Model Gut System is a lab model stretching from the mouth to the large intestine which can be used to test drug delivery and absorption, screen formulations, develop and test functional foods and study pre- and pro- biotics. Aelius Biotech aim to help customers understand, develop and test formulations at the vital pre-clinical stages. Visit Aelius Biotech website. 

Atelerix

Atelerix offers a transformative hydrogel technology for the storage and transport of viable cells including stem cells and cell-based assays at ambient temperatures. This overcomes the barriers presented by the current need for cryo-shipping as it is simple, cell-friendly and offers immediate access to stem cell therapies. Visit the Atelerix website. 

3D Biotissues

3D Biotissues transplantable corneas using 3D bio-printing. The company is a leading provider of cutting-edge technologies in corneal 3D printing. Founded by Professor Che Connon at Newcastle University, using knowledge of corneal biology gained after 20 years of performing cutting edge research into a fundamental understanding of how the cornea works. Visit the 3D Biotissues website. 

Demuris (now part of Odyssey Therapeutics)

Demuris was set up as a drug discovery and development company employing state-of-the-art platform technologies in natural product discovery, design and production. The starting point for Demuris’ portfolio of new drug development often lies in a unique collection of Actinomycete bacteria. These organisms can manipulate the behaviour of surrounding organisms, including bacteria, fungi, plants and animals. Demuris is now part of Odyssey Therapeutics.

Newcells Biotech

Newcells Biotech’s expertise is in the production of induced pluripotent stem cells and their differentiation into a wide range of reliable and reproducible cell and tissue types. The company aims to provide customers engaged in drug discovery, pre-clinical development and disease mechanism investigation, with the best quality cells and services. Visit the Newcells Biotech’s website. 

FibroFind (sold in April 2025 to Parios Capital Limited)

FibroFind combines decades of research experience with our robust preclinical drug development testbeds to provide world-class research solutions in liver, kidney and lung disease. Visit the FibroFind website.

MarraBio

MarraBio started as a spinout at Newcastle University in 2023, with the goal of commercialising the Cytocaf technology that had been pioneered there. MarraBio’s proprietary engineered Cytocaf proteins provide an easy to use, ultra stable, scalable and xeno-free alternative to the extracellular matrix proteins and growth factors used in mammalian cell culture. Visit the MarraBio website.