Staff Profile

Consultant in neonatal medicine in the Newcastle Neonatal Service since 2006.

Associate clinical lecturer at Newcastle

MD in neonatal immunology 

MD superviser: targeted screening for congenital CMV (2009-12) and neonatal microbiome (2013-)

Research interersts are neonatal infection/immunology, changing patterns of neonatal infectious mortality/morbidity, congenital CMV, neonatal microbiome (and other omics), prioritisation and delivery of neonatal research.

Deputy chair of neonatal MCRN CSG

Current portfolio contributions: 

Co-applicant on SIFT (speed of increased feeding trial) and ELFIN (emteral lactoferrin in neonates) trials  

PI of REDEXAM (reducing eye examinations in preterm infants)

• Williams EJ, Embleton ND, Bythell M, Platt MPW, Berrington JE. The changing profile of infant mortality from bacterial, viral and fungal infection over two decades. Acta Paediatrica 2013, 102(10), 999-1004.
• Williams EJ, Embleton ND, Clark JE, Bythell M, Platt MPW, Berrington JE. Viral Infections: Contributions to Late Fetal Death, Stillbirth, and Infant Death. Journal of Pediatrics 2013, 163(2), 424-428.
• Berrington JE, Hearn RI, Bythell M, Wright C, Embleton ND. Deaths in Preterm Infants: Changing Pathology Over 2 Decades. Journal of Pediatrics 2012, 160(1), 49-U94.
• Stewart CJ, Marrs ECL, Magorrian S, Nelson A, Lanyon C, Perry JD, Embleton ND, Cummings SP, Berrington JE. The preterm gut microbiota: changes associated with necrotizing enterocolitis and infection. Acta Paediatrica 2012, 101(11), 1121-1127.
• Atkinson E, George SM, Shafiq A, Clark JE, Ogjnanovic M, Berrington JE. Two high pressure conundrums and a possible congenital link. Archives of Disease in Childhood: Education and Practice Edition 2011, 96(6), 210-215.
• Embleton ND, Berrington J. Giving vancomycin as a continuous infusion. In: Archives of Disease in Childhood: Fetal and Neonatal Edition. 2009, BMJ Group.
• Berrington JE, Fenton AC, Arnaoutakis K, Zhang Q, Finn A. Avidity of Haemophilus influenzae type b antibody in UK infants. Archives of Disease in Childhood 2007, 92(9), 827-827.
• Berrington JE, Cant AJ, Matthews JNS, O'Keeffe M, Spickett GP, Fenton AC. Haemophilus influenzae type b immunization in infants in the United Kingdom: Effects of diphtheria/tetanus/acellular pertussis/Hib combination vaccine, significant prematurity, and a fourth dose. Pediatrics 2006, 117(4), e717-e724.
• Berrington JE, Fenton AC, Cant AJ, Spickett GP, O'Keeffe M, Matthews JNS. Reduced anti-PRP antibody response to Hib immunisation in preterm (<32 weeks) UK infants who received inactivated polio (eIPV). Vaccine 2007, 25(49), 8206-8208.
• Fenton AC, Berrington JE, Spickett GP, Cant AJ, O'Keeffe M, Matthews JN. Haemaphilus influenzaeType b (Hib) antibody response following pragmatic UK immunisation with mixed regimes of acellular and/or whole cell DTPHib combination vaccines. In: Annual Meeting of the Pediatric Academic Societies. 2004, San Francisco, CA: Pediatric Research: International Pediatric Research Foundation.
• Berrington JE, Fenton A. Interpreting immunogenicity data in UK studies. Archives of Disease in Childhood 2005, 90(11), 1205.
• Berrington J, Fenton A. Immunization responses in preterm infants who receive postnatal steroid treatment. Pediatrics 2004, 114(4), 1127-1128.
• Berrington JE, Barge D, Fenton AC, Cant AJ, Spickett GP. Lymphocyte subsets in term and significantly preterm UK infants in the first year of life analysed by single platform flow cytometry. Clinical and Experimental Immunology 2005, 140(2), 289-292.
• Berrington JE, Fenton AC, Spickett GP, Cant AJ. Haemophilus influenzae type b (Hib) antibody response in significantly preterm UK infants. In: Pediatric Research: Annual Meeting of the Pediatric Academic Society. 2003, Seattle, Washington, USA: Lippincott Williams & Wilkins.
• Hall CM, Milligan DWA, Berrington J. Probable adverse reaction to a pharmaceutical excipient. Archives of Disease in Childhood - Fetal and Neonatal Edition 2004, 89(2), F184-F184.
• Berrington JE, Flood TJ, Abinun M, Galloway A, Cant AJ. Unsuspected Pneumocystis carinii pneumonia at presentation of severe primary immunodeficiency. Archives of Disease in Childhood 2000, 82(2), 144-147.
• Zalewski S, Stewart CJ, Embleton ND, Berrington JE. Brief guide to the analysis, interpretation, and presentation of microbiota data. Archives of Disease in Childhood: Education and Practice Edition 2017, 103(6), 327-330.
• Stewart CJ, Embleton ND, Clements E, Luna PN, Smith DP, Fofanova TY, Nelson A, Taylor G, Orr CH, Petrosino JF, Berrington JE, Cummings SP. Cesarean or vaginal birth does not impact the longitudinal development of the gut microbiome in a cohort of exclusively preterm infants. Frontiers in Microbiology 2017, 8, 1008.
• Shillitoe BMJ, Berrington J, Athiraman N. Congenital pleural effusions: 15 years single-centre experience from North-East England. Journal of Maternal-Fetal and Neonatal Medicine 2018, 31(15), 2086-2089.
• Nguyen DN, Stensballe A, Lai JCY, Jiang P, Brunse A, Li Y, Sun J, Mallard C, Skeath T, Embleton ND, Berrington JE, Sangild PT. Elevated levels of circulating cell-free DNA and neutrophil proteins are associated with neonatal sepsis and necrotizing enterocolitis in immature mice, pigs and infants. Innate Immunity 2017, 23(6), 524-536.
• Stewart CJ, Embleton ND, Marrs ECL, Smith DP, Fofanova T, Nelson A, Skeath T, Perry JD, Petrosino JF, Berrington JE, Cummings SP. Longitudinal development of the gut microbiome and metabolome in preterm neonates with late onset sepsis and healthy controls. Microbiome 2017, 5(1), 75.
• Embleton ND, Berrington JE, Dorling J, Ewer AK, Juszczak E, Kirby JA, Lamb CA, Lanyon CV, McGuire W, Probert CS, Rushton SP, Shirley MD, Stewart CJ, Cummings SP. Mechanisms Affecting the Gut of Preterm Infants in Enteral Feeding Trials. Frontiers in Microbiology 2017, 4, 14.
• Young GR, Smith DL, Embleton ND, Berrington JE, Schwalbe EC, Cummings SP, van der Gast CJ, Lanyon C. Reducing Viability Bias in Analysis of Gut Microbiota in Preterm Infants at Risk of NEC and Sepsis. Frontiers in Cellular and Infection Microbiology 2017, 7, 237.
• Nguyen DN, Stensballe A, Lai J, Jiang P, Li Y, Sun J, Mallard C, Skeath T, Embleton N, Berrington J, Sangild P. Circulating neutrophil extracellular trap components are associated with sepsis and necrotizing enterocolitis in newborn, immature infants, pigs and mice. In: The 6th Congress of the European Academy of Paediatric Societies (EAPS). 2016, Geneva, Switzerland: Springer.
• Skeath T, Stewart CJ, Waugh S, Embleton ND, Cummings SP, Berrington JE. Cytomegalovirus and other common enteric viruses are not commonly associated with Necrotizing Enterocolitis. Acta Paediatrica 2016, 105(1), 50-52.
• Stewart CJ, Nelson A, Treumann A, Skeath T, Cummings SP, Embleton ND, Berrington JE. Metabolomic and proteomic analysis of serum from preterm infants with necrotising entercolitis and late-onset sepsis. Pediatric Research 2016, 79(3), 425-431.
• Embleton ND, Zalewski S, Berrington JE. Probiotics for prevention of necrotizing enterocolitis and sepsis in preterm infants. Current Opinion in Infectious Diseases 2016, 29(3), 256-261.
• Berrington J, Ward-Platt M. Recent advances in the management of infants born <1000 g. Archives of Disease in Childhood 2016, 101(11), 1053-1056.
• Abdulkadir B, Nelson A, Skeath T, Marrs ECL, Perry JD, Cummings SP, Embleton ND, Berrington JE, Stewart CJ. Routine use of probiotics in preterm infants: longitudinal impact on the microbiome and metabolome. Neonatology 2016, 109(4), 239-247.
• Abdulkadir B, Nelson A, Skeath T, Marrs ECL, Perry JD, Cummings SP, Embleton ND, Berrington JE, Stewart CJ. Stool bacterial load in preterm infants with necrotising enterocolitis. Early Human Development 2016, 95, 1-2.
• Stewart CJ, Embleton ND, Marrs ECL, Smith DP, Nelson A, Abdulkadir B, Skeath T, Petrosino JF, Perry JD, Berrington JE, Cummings SP. Temporal bacterial and metabolic development of the preterm gut reveals specific signatures in health and disease. Microbiome 2016, 4, 67.
• Kadambari S, Luck S, Davis A, Walter S, Agrup C, Atkinson C, Stimson L, Williams E, Berrington J, Griffiths P, Sharland M. Evaluating the feasibility of integrating salivary testing for congenital CMV into the Newborn Hearing Screening Programme in the UK. European Journal of Pediatrics 2015, 174(8), 1117-1121.
• Williams EJ, Gray J, Luck S, Atkinson C, Embleton ND, Kadambari S, Davis A, Griffiths P, Sharland M, Berrington JE, Clark JE. First estimates of the potential cost and cost saving of protecting childhood hearing from damage caused by congenital CMV infection. Archives of Disease in Childhood - Fetal and Neonatal Edition 2015, 100(6), F501-F506.
• Stewart CJ, Skeath T, Nelson A, Fernstad SJ, Marrs ECL, Perry JD, Cummings SP, Berrington JE, Embleton ND. Preterm gut microbiota and metabolome following discharge from intensive care. Scientific Reports 2015, 5, 17141.
• Williams EJ, Kadambari S, Berrington JE, Luck S, Atkinson C, Walter S, Embleton ND, James P, Griffiths P, Davis A, Sharland M, Clark JE. Feasibility and acceptability of targeted screening for congenital CMV-related hearing loss. Archives of Disease in Childhood: Fetal and Neonatal Edition 2014, 99(3), F230-F236.
• Berrington JE, Hearn RI, Hall C, Stewart CJ, Cummings SP, Embleton ND. Proportionate Reduction in Uncertainty of Late Onset Infection in Pre-term Infants by Neutrophil CD64 Measurement. Fetal & Pediatric Pathology 2014, 33(1), 16-22.
• Berrington JE, Cummings SP, Embleton ND. The Nasopharyngeal Microbiota: An Important Window of Opportunity. American Journal of Respiratory and Critical Care Medicine 2014, 190(3), 246-248.
• Berrington JE, Stewart CJ, Cummings SP, Embleton ND. The neonatal bowel microbiome in health and infection. Current Opinion in Infectious Diseases 2014, 27(3), 236-243.
• Stewart CJ, Nelson A, Scribbins D, Marrs ECL, Lanyon C, Perry JD, Embleton ND, Cummings SP, Berrington JE. Bacterial and fungal viability in the preterm gut: NEC and sepsis. Archives of Disease in Childhood - Fetal and Neonatal Edition 2013, 98(4), F298-F303.
• Kadambari S, Luck S, Davis A, Williams EJ, Berrington J, Griffiths PD, Sharland M. Clinically targeted screening for congenital CMV - potential for integration into the National Hearing Screening Programme. Acta Paediatrica 2013, 102(10), 928-933.
• Stewart CJ, Marrs ECL, Nelson A, Lanyon C, Perry JD, Embleton ND, Cummings SP, Berrington JE. Development of the Preterm Gut Microbiome in Twins at Risk of Necrotising Enterocolitis and Sepsis. PLoS ONE 2013, 8(8), e73465.
• Berrington JE, Stewart CJ, Embleton ND, Cummings SP. Gut microbiota in preterm infants: assessment and relevance to health and disease. Archives of Disease in Childhood - Fetal and Neonatal Edition 2013, 98(4), F286-F290.
• Embleton ND, Berrington JE, McGuire W, Stewart CJ, Cummings SP. Lactoferrin: Antimicrobial activity and therapeutic potential. Seminars in Fetal and Neonatal Medicine 2013, 18(3), 143-149.
• Embleton ND, Turnbull E, Turner S, Berrington JE. Successful blood salvaging from preterm infants: maximizing opportunities, minimizing interventions. Acta Paediatrica 2013, 102(11), e527-e529.
• Berrington JE, Stafford FW, Macphail S. Emergency EXIT for preterm labour after FETO. ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION 2010, 95(5), F376-F377.
• Tinnion RJ, Berrington JE. Flu vaccination for ex-preterms and infants under 6 months-are we getting it right?. ARCHIVES OF DISEASE IN CHILDHOOD 2010, 95(5).